Failure of a synthetic, anti-inflammatory compound to alter the efficiency of the IUD.

Abstract:

:Holtzman, female rats with a plastic or copper IUD were maintained on either a dexamethasone solution (9.4 or 28 micrograms/rat/day) in the drinking water or on water alone. Animals were caged with males of proven fertility and subsequently killed at day 14 of pregnancy and the number of implantation sites counted. Both types of IUDs were effective in preventing implantation. Implantation sites were not increased in dexamethasone-treated animals. In addition, proestrous gonadotropin levels and follicular development did not differ between treated and nontreated animals. Thus, the data demonstrate that the efficacy of the IUD is not decreased with the use of anti-inflammatory drugs.

journal_name

Gynecol Obstet Invest

authors

Peppler RD,Molony T,Bast JD

doi

10.1159/000299826

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

88-94

issue

2

eissn

0378-7346

issn

1423-002X

journal_volume

11

pub_type

杂志文章
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