The stimulation of prolactin secretion by taurine: studies on the site of action.

Abstract:

:Taurine's site of action within the central nervous system was localized by studying its effect on prolactin secretion following the microinfusion of 125 nmoles of this amino acid into discrete regions of the brain. Taurine was found to stimulate prolactin secretion only when microinfused into the arcuate nucleus of the hypothalamus. Taurine was not effective in other areas of the hypothalamus or in several extra-hypothalamic sites. Mannitol infusions (125 nmoles) into the arcuate nucleus, used as a control, were without effect on prolactin secretion. These studies extend previous observations on the prolactin-releasing action of centrally administered taurine and suggest further that the arcuate nucleus is one target site for this action.

journal_name

Brain Res Bull

journal_title

Brain research bulletin

authors

Scheibel J,Elsasser T,Brown B,Dom R,Ondo JG

doi

10.1016/0361-9230(84)90007-8

subject

Has Abstract

pub_date

1984-07-01 00:00:00

pages

49-52

issue

1

eissn

0361-9230

issn

1873-2747

pii

0361-9230(84)90007-8

journal_volume

13

pub_type

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