Suppressor of cytokine signaling 2 (SOCS2) contributes to encephalitis in a model of Herpes infection in mice.

abstract：:Reserpine depletes dopamine (DA) levels and increases tyrosine hydroxylase (TH) activity in the rat corpus striatum. TH is activated not only by enhancement of DA neuronal impulse flow, but also by cessation of impulse flow. To assist in the understanding of the relative contribution of impulse flow to the regulation ...

journal_title：Brain research bulletin

authors： German DC,McMillen BA,Sanghera MK,Saffer SI,Shore PA

更新日期：1981-02-01 00:00:00

abstract：:Previous studies suggest that hypnotizability represents a protective factor against the cardiac effects of cognitive stress and that hypnosis prevents vascular stress-induced modifications in highly hypnotizable individuals. The aim of the experiment was to investigate whether a similar effect at vascular level is pr...

journal_title：Brain research bulletin

authors： Jambrik Z,Santarcangelo EL,Ghelarducci B,Picano E,Sebastiani L

更新日期：2004-04-30 00:00:00

abstract：:Microtubule associated proteins are a heterogeneous group of proteins that have been implicated in regulating microtubule stability. They play an important role in the organisation of the neuronal cytoskeleton during neurite outgrowth, plasticity and regeneration. The fish visual system presents a considerable degree ...

journal_title：Brain research bulletin

authors： Vecino E,Avila J

更新日期：2001-09-15 00:00:00

abstract：:The susceptibility of the developing brain to hypoxia should depend on the lipid composition of the brain cell membrane; the rate of lipid peroxidation; the presence of antioxidant defenses; and the development and modulation of the excitatory neurotransmitter receptors such as the N-methyl-D-aspartate (NMDA) receptor...

journal_title：Brain research bulletin

authors： Mishra OP,Delivoria-Papadopoulos M

更新日期：1999-02-01 00:00:00

abstract：:Specific angiotensin II (Ang II) binding sites are present in the dorsal medulla of several species, and dose-related cardiovascular effects are produced by microinjection of the peptide into this region. Because the anatomical location of Ang II binding sites in the area postrema (ap), nucleus tractus solitarii (nTS)...

journal_title：Brain research bulletin

authors： Diz DI,Barnes KL,Ferrario CM

更新日期：1986-10-01 00:00:00

abstract：:A newly developed technique employing the retrograde transport of horseradish peroxidase combined with immunocytochemistry is used to identify the cells of origin of descending spinal pathways and their putative neurotransmitters. With this technique the brainstem origins of descending serotonergic (5HT) pathways to t...

journal_title：Brain research bulletin

authors： Bowker RM,Westlund KN,Coulter JD

更新日期：1982-07-01 00:00:00

abstract：:Although neural occlusion has been suggested to occur between the central and reflex mechanisms increasing arterial pressure, evidence consistent with this phenomenon is lacking. To assess the possibility of neural occlusion we recorded, in chloralose-anesthetized cats, the pressor responses to statically contracting ...

journal_title：Brain research bulletin

authors： Rybicki KJ,Stremel RW,Iwamoto GA,Mitchell JH,Kaufman MP

更新日期：1989-02-01 00:00:00

abstract：:Endogenous pyrogen (EP), injected systemically or intracerebrally, evokes fever and certain changes in plasma trace metal and glycoprotein levels which are characteristic of the acute-phase reaction. It is generally assumed that EP enters the brain from the blood, although it has not yet been demonstrated that EP cros...

journal_title：Brain research bulletin

authors： Blatteis CM,Bealer SL,Hunter WS,Llanos-Q J,Ahokas RA,Mashburn TA Jr

更新日期：1983-11-01 00:00:00

abstract：:High dietary salt intake activates the brain renin-angiotensin system in spontaneously hypertensive rats (SHR) and Dahl S rats, resulting in sympathetic hyperactivity and hypertension. Increases of sodium concentration in cerebrospinal fluid (CSF) and/or enhanced responses to CSF sodium are considered to be involved i...

journal_title：Brain research bulletin

authors： Kubo T,Hagiwara Y

更新日期：2006-01-30 00:00:00

abstract：:To clarify the role of febrile temperatures on the immune system, rats were immunized with sheep erythrocytes and their core temperature was then changed by continuously cooling or heating the preoptic area for five days. Core temperatures of up to 2 degrees C above or below normal were associated with a high titre of...

journal_title：Brain research bulletin

authors： Brandt S,Banet M

更新日期：1984-08-01 00:00:00

abstract：:Nicotinic acetylcholine (ACh) and dopamine (DA) receptor activation has been found to be important for working memory. The regional distribution of these receptors in the brain has been well characterized. However, the relationship of the region-specific nicotinic ACh and DA binding density to memory performance has n...

journal_title：Brain research bulletin

authors： Levin ED,Torry D,Christopher NC,Yu X,Einstein G,Schwartz-Bloom RD

更新日期：1997-01-01 00:00:00

abstract：:The development of morphine-induced antinociceptive tolerance limits its therapeutic efficacy in pain management. Atorvastatin, or competitive inhibitor of 3-hydroxy-methyl-glutaryl coenzyme A (HMG-CoA) reductase, is mainstay agent in hypercholesterolemia treatment. Beyond the cholesterol-lowering activity, exploratio...

journal_title：Brain research bulletin

authors： Hassanipour M,Amini-Khoei H,Shafaroodi H,Shirzadian A,Rahimi N,Imran-Khan M,Rezayat SM,Dehpour A

更新日期：2016-07-01 00:00:00

abstract：:The present study examined the changes of extracellular concentration of dopamine and its metabolite homovanillic acid in the striatum, the periaqueductal gray and the dorsal horn of lumbar spinal cord following intraplantar injection of carrageenan. In vivo microdialysis and high-performance liquid chromatography wit...

journal_title：Brain research bulletin

authors： Gao X,Zhang YQ,Zhang LM,Wu GC

更新日期：2001-03-01 00:00:00

abstract：:Calcitonin, a peptide hormone expressed in C-cells of the thyreoid gland, as well as capsaicin, isolated from chili, both, modify intracellular signalling in nociceptive neurones. The pathways triggered by the activation of either of these receptors results in a modulation of the intracellular calcium ([Ca(2+)](i)) co...

journal_title：Brain research bulletin

authors： Hagenacker T,Ledwig D,Büsselberg D

更新日期：2011-04-25 00:00:00

abstract：:Binary mixtures of acid with salt were observed to produce enhancing effects on oral chemoreceptor responses by recording the activity of the whole glossopharyngeal nerve of the clawed toad (Xenopus laevis). The mixtures of HCl with various inorganic salts elicited responses larger than the sum of the responses to ind...

journal_title：Brain research bulletin

authors： Yamashita S,Hisadome K,Yotsumata Y,Kiyohara S

更新日期：1997-01-01 00:00:00

abstract：:The present study investigated whether the raphe neurons which give rise to the transient serotonergic fibers in the visual cortex of neonatal rats persist or disappear as the rats mature. Three experiments were performed employing the WGA-apoHRP-Au retrograde transport technique in conjunction with 5-HT or WGA-HRP im...

journal_title：Brain research bulletin

authors： Koh T,Nakazawa M,Kani K,Maeda T

更新日期：1991-11-01 00:00:00

abstract：:Comparative studies on developmental gene expression suggest that the ancestral chordate central nervous system comprised anterior, midbrain-hindbrain boundary (MHB) and posterior regions. The most anterior region consists of both forebrain and midbrain in vertebrates. It remains, however, unresolved when or how the v...

journal_title：Brain research bulletin

authors： Takahashi T

更新日期：2005-09-15 00:00:00

abstract：:The forebrain is characterized by a dense, localized dopamine (DA) innervation pattern, a diffuse, widespread norepinephrine (NE) innervation pattern, and a serotonin (5-HT) innervation intermediate between the DA and NE patterns. These innervation patterns have implied that basic differences exist in the way DA, NE a...

journal_title：Brain research bulletin

authors： Fallon JH,Loughlin SE

更新日期：1982-07-01 00:00:00

abstract：:In a previous study, it was shown that the lateral entorhinal cortex (LEC) in the left hemisphere contains higher concentration of glutamate than in the right hemisphere. The purpose of the present study was to examine potential relationship between this neurochemical asymmetry and behavior. Rats with either left, rig...

journal_title：Brain research bulletin

authors： Myhrer T,Iversen EG

更新日期：1990-08-01 00:00:00

abstract：:Rats received bilateral intracerebroventricular (ICV) infusions of either AF64A (1.5 nmol/ventricle; n = 9) or vehicle (3.0 microliters/ventricle; n = 7). Four weeks later, the animals were anesthetized and their brains processed to visualize and quantify choline acetyltransferase (ChAT) immunoreactive (IR) and parval...

journal_title：Brain research bulletin

authors： Dong XW,Hanin I,Lorens SA

更新日期：1994-01-01 00:00:00

abstract：:Neonatal hippocampal lesions in rats produce behavioral and neurochemical abnormalities post-puberty that are used in animal models for developmentally linked pathology in schizophrenia. In one model, adult rats exhibit enhanced sensitivity to the locomotor-activating effects of amphetamine, if they had sustained exci...

journal_title：Brain research bulletin

authors： Swerdlow NR,Halim N,Hanlon FM,Platten A,Auerbach PP

更新日期：2001-05-01 00:00:00

abstract：:Every year, a large number of infants and young children worldwide are administered general anesthesia. Whether general anesthesia adversely affects the intellectual development and cognitive function of children at a later date remains controversial. Many animal experiments have shown that general anesthetics can cau...

journal_title：Brain research bulletin

authors： Yang F,Zhao H,Zhang K,Wu X,Liu H

更新日期：2020-11-01 00:00:00

abstract：:Chronic brain implants are accompanied by a tissue response that causes the loss of neurons in the vicinity of the implant and the formation of a glial scar that is also referred to as foreign body response. Despite immense progress in the field of brain-computer interface (BCI) research the biocompatibility of chroni...

journal_title：Brain research bulletin

authors： Hayn L,Koch M

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:Parkinson's disease (PD) is a frequent degenerative disease of the nervous system with undefined pathogenesis. This study explored the protective effect of microRNA (miR)-218-5p on dopaminergic neuron injury in substantia nigra (SN) of rats with PD through the regulation of LIM and SH3 domain protein 1 (LASP1...

journal_title：Brain research bulletin

authors： Ma X,Zhang H,Yin H,Geng S,Liu Y,Liu C,Zhao J,Liu Y,Wang X,Wang Y

更新日期：2021-01-01 00:00:00

abstract：:According to recently published papers acylated-ghrelin (A-Ghr) modifies memory and learning. The basolateral nucleus of amygdala (ABL) participates in the regulation of memory and learning mechanisms. Previously we verified A-Ghr responsive neurons in the ABL by electrophysiological methods. In male Wistar rats effec...

journal_title：Brain research bulletin

authors： Tóth K,László K,Lénárd L

更新日期：2010-01-15 00:00:00

abstract：:Our previous results showed that neurochemical destruction of the amygdaloid terminal field of the mesolimbic dopaminergic system caused disturbances in body weight regulation and feeding. In the present experiments, it was studied whether 6-hydroxydopamine (6-OHDA)-induced bilateral lesions of the mesolimbic dopamine...

journal_title：Brain research bulletin

authors： Lénárd L,Karádi Z,Jandó G,Yoshimatsu H,Hajnal A,Sándor P,Oomura Y

更新日期：1991-09-01 00:00:00

abstract：:Complex interactions between genetic and environmental factors exert a sustained influence on the pathogenesis of schizophrenia (SCZ). Adolescent social isolation is regarded as a typical paradigm for SCZ. However, the underlying pathological mechanisms are not fully understood. In this study, adolescent Sprague-Dawle...

journal_title：Brain research bulletin

authors： Sun L,Min L,Li M,Shao F,Wang W

更新日期：2018-09-01 00:00:00

abstract：:Transcription factor Pbx4 is recruited to form dimeric or trimeric complexes with Hox and/or Meis homeodomain proteins and participates in patterning the hindbrain and retina during vertebrate CNS development. We characterized a Pbx4 cDNA isolated from a Gekko japonicus brain and spinal cord cDNA library. Northern blo...

journal_title：Brain research bulletin

authors： Wang Y,Jiang X,Liu Y,Gu X,Huan Y,Ren L,Ding F,Gu X

更新日期：2009-12-16 00:00:00

abstract：:Autophagy is the lysosome-mediated bulk degradation of cellular components for material recycling to maintain cellular homeostasis. Autophagy was initially regarded as a nonselective process, however, recent evidence indicates that this process can in fact be highly selective, especially for targeting and degrading or...

journal_title：Brain research bulletin

authors： Wu MY,Song JX,Wang SF,Cai CZ,Li M,Lu JH

更新日期：2018-03-01 00:00:00

abstract：:Evidence concerning the presence or absence of common neuronglia lineages in the postnatal mammalian central nervous system is still a matter of speculation. We address this problem using optic nerve explants, which show an extremely long survival in culture. Morphological, immunocytochemical and immunochemical method...

journal_title：Brain research bulletin

authors： Omlin FX,Riederer BM

更新日期：1992-01-01 00:00:00