Abstract:
:We have isolated and sequenced the complete murine I-E alpha immune response gene of the H-2db haplotype. The I-E alpha d gene consists of 5300 basepairs and is organized into five or possibly six exons that correspond to different domains of the alpha chain. The amino acid sequence deduced from the I-E alpha gene shows 75% homology to its human counterpart, the HLA-DR alpha chain. The absence of I-E antigen in H-2 mice is due to lack of E alpha chain synthesis. We show here that this defect is caused by a deletion in the 5' end of the I-E alpha b gene.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Hyldig-Nielsen JJ,Schenning L,Hammerling U,Widmark E,Heldin E,Lind P,Servenius B,Lund T,Flavell R,Lee JS,Trowsdale J,Schreier PH,Zablitzky F,Larhammar D,Peterson PA,Rask Ldoi
10.1093/nar/11.15.5055subject
Has Abstractpub_date
1983-08-11 00:00:00pages
5055-71issue
15eissn
0305-1048issn
1362-4962journal_volume
11pub_type
杂志文章abstract::Eukaryotic gene expression is regulated by enhancer-promoter interactions but the molecular mechanisms that govern specificity have remained elusive. Genome-wide studies utilizing STARR-seq identified two enhancer classes in Drosophila that interact with different core promoters: housekeeping enhancers (hkCP) and deve...
journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkw1114
更新日期:2017-02-28 00:00:00
abstract::The polymerase encoded by human hepatitis B virus, which has reverse transcriptase and RNase H activity, binds to its pregenomic RNA template in a two-step process involving a terminal redundancy. Both first strand and second strand DNA synthesis involve primer translocation and second strand synthesis involves a temp...
journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/24.17.3295
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkq410
更新日期:2010-10-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gks395
更新日期:2012-09-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkq364
更新日期:2010-10-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/17.23.10047
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2008-01-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/16.9.3771
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/21.15.3513
更新日期:1993-07-25 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2001-12-15 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2014-02-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkm889
更新日期:2008-01-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkw1254
更新日期:2017-03-17 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gky378
更新日期:2018-07-02 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:1986-04-25 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkh957
更新日期:2004-12-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2002-01-01 00:00:00
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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更新日期:2004-06-17 00:00:00
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/23.5.835
更新日期:1995-03-11 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2001-07-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:1977-08-01 00:00:00
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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更新日期:1995-08-11 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkq050
更新日期:2010-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/nar/27.10.2175
更新日期:1999-05-15 00:00:00