Multiplicity of opiate receptors in different species.

Abstract:

:Three populations of opiate binding sites (mu, delta and kappa) could be distinguished by displacement studies with the mu-agonist (D)-Ala2-MePhe4-Glyol5-enkephalin and the kappa-agonist [3H](-)-bremazocine in brain membranes of different species. Whereas brain membranes from pig or guinea-pig and human cortical membranes had a proportion of approximately 35-50% kappa-, 29-40% mu-, and 21-30% delta-binding sites, rat membranes contained much less kappa-sites (12% kappa, 62% mu and 25% delta).

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Maurer R

doi

10.1016/0304-3940(82)90417-7

subject

Has Abstract

pub_date

1982-06-30 00:00:00

pages

303-7

issue

3

eissn

0304-3940

issn

1872-7972

pii

0304-3940(82)90417-7

journal_volume

30

pub_type

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