Abstract：
:We have studied the effects of ketanserin, a specific 5-HT2 antagonist, and zimelidine, a selective inhibitor of 5-HT re-uptake into central nervous system presynaptic terminals, upon basal and TRH stimulated serum TSH and prolactin levels in euthyroid individuals. Ten normal volunteers were studied (five male and five female), each receiving oral ketanserin and oral zimelidine during respective seven day periods, separated by an interval of at least two weeks. A standard TRH test (200 micrograms i.v.) was carried out before and after each period of drug administration, serum samples being obtained for TSH and prolactin estimation. We were unable to demonstrate any modification of basal or TRH-stimulated TSH and prolactin levels by the oral administration of either ketanserin or zimelidine, suggesting that 5-HT has no significant role in the physiological release of either TSH or prolactin.
journal_name
Psychoneuroendocrinologyjournal_title
Psychoneuroendocrinologyauthors
O'Malley BP,Jennings PE,Cook N,Barnett DB,Rosenthal FDdoi
10.1016/0306-4530(84)90017-9subject
Has Abstractpub_date
1984-01-01 00:00:00pages
13-9issue
1eissn
0306-4530issn
1873-3360journal_volume
9pub_type
杂志文章abstract：:We injected ovariectomized female rats with estrogen and progesterone. Some of the injection regimens used are known to induce estrus, while other do not. The effects of these treatments on operant behavior were evaluated. Operant behavior was maintained under a reinforcement schedule, one segment of which involved ex...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/0306-4530(84)90008-8
更新日期：1984-01-01 00:00:00
abstract：:Previous research links contemplative practices, such as meditation, with stress reduction. However, little is known about the psychological mechanisms underlying this relationship. This study compares the physiological stress response (reactivity and recovery) measured by changes in salivary cortisol, heart rate, hea...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2019.02.026
更新日期：2019-06-01 00:00:00
abstract：:IQ change in association with change of environment occurred in a sample of 34 patients with a diagnosis of abuse dwarfism. Low and persistent impairment of IQ was associated with abuse. By contrast, IQ elevation was associated with rescue. Multiple regression analysis revealed that duration of rescue was the primary ...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/0306-4530(83)90005-7
更新日期：1983-01-01 00:00:00
abstract：:A wealth of evidence has linked individual differences in testosterone (T) to social, cognitive, and behavioral processes related to human dominance. Moreover, recent evidence indicates that a single administration of T reduces interpersonal trust in healthy young women. Here, in a sample of men and women (n=96), we i...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2014.06.011
更新日期：2014-11-01 00:00:00
abstract：:The TSH response to TRH has been reported to be blunted in endogenous depression. We compared two radioimmunoassay (RIA) techniques of TSH in 21 subjects (7 psychiatric inpatients, 14 normal controls) to determine whether differences in assay could account for discrepancies in the reported prevalence rates of blunted ...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/0306-4530(83)90027-6
更新日期：1983-01-01 00:00:00
abstract：:Caffeine is a commonly used psychoactive substance and consumption by children and adolescents continues to rise. Here, we examine the lasting effects of adolescent caffeine consumption on anxiety-related behaviors and several neuroendocrine measures in adulthood. Adolescent male Sprague-Dawley rats consumed caffeine ...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2016.01.030
更新日期：2016-05-01 00:00:00
abstract：:Prenatal exposure to testosterone has been shown to affect fetal brain maturation as well as postnatal cognition and behavior in animal studies. Although there are well-established sex-differences in the use of social communication (or 'pragmatic language') in humans, there has been limited investigation of the associ...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2010.02.007
更新日期：2010-09-01 00:00:00
abstract：:In humans, oxytocin nasal administration reduces social-threat perception and improves processes involved in communication and the encoding of positive social cues. The aim of this study was to determine whether oxytocin given as an adjunct to exposure therapy improves treatment for social anxiety disorder (SAD) as in...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psyneuen.2009.01.005
更新日期：2009-07-01 00:00:00
abstract：BACKGROUND:While enhanced cortisol suppression in response to dexamethasone is one of the most consistent biological findings in posttraumatic stress disorder (PTSD), the relative contribution of trauma exposure to this finding remains unclear. METHODS:Assessment of diurnal salivary cortisol levels and 1600 h salivary...
journal_title：Psychoneuroendocrinology
pub_type： 临床试验,杂志文章
doi：10.1016/j.psyneuen.2006.12.009
更新日期：2007-04-01 00:00:00
abstract：:The nature of hormonal involvement in pubertal brain development has attracted wide interest. Structural changes within the brain that occur during pubertal development appear mainly in regions closely linked with emotion, motivation and cognitive functions. Using a sheep model, we have previously shown that peri-pube...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2013.09.011
更新日期：2013-12-01 00:00:00
abstract：:Acute stress is known to increase prosocial behavior in men via a "tend-and-befriend" pattern originally proposed as a specifically female stress response alongside the fight-or-flight response. However, the direct effects of acute stress on women's social behavior have not been investigated. Applying the Trier Social...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2018.08.031
更新日期：2019-01-01 00:00:00
abstract：:Stress is thought to alter motivational processes by increasing dopamine (DA) secretion in the brain's "reward system", and its key region, the nucleus accumbens (NAcc). However, stress studies using functional magnetic resonance imaging (fMRI), mainly found evidence for stress-induced decreases in NAcc responsiveness...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psyneuen.2013.10.005
更新日期：2014-01-01 00:00:00
abstract：:The effects of pregnancy on cognition and mood were examined using a repeated-measures design. Nineteen women, average age 33, were tested with a comprehensive neuropsychological battery during their last 2 months of pregnancy and again within 2 months of delivery. Blood samples were obtained from all subjects and ass...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/s0306-4530(98)00044-4
更新日期：1999-01-01 00:00:00
abstract：:Depression is characterized by hypothalamo-pituitary-adrenocortical (HPA) axis hyperactivity. In this major mood disorder, neurosteroids and neurotrophins, particularly brain-derived neurotrophic factor (BDNF), seem to be implicated and have some antidepressant effects. BDNF is highly involved in regulation of the HPA...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2007.09.002
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVE:There is evidence that microRNA-195 (miR-195) is associated with schizophrenia (SZ) and cognition, but the relationship between miR-195 and cognitive impairment in SZ is still unknown. Sex differences in both microRNA (miRNA) expression and cognition were found in SZ. We aim to investigate whether sex moderat...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2020.104748
更新日期：2020-09-01 00:00:00
abstract：:The peptide hormone oxytocin (OT) plays an important role in social behaviors, including social bond formation. In different contexts, however, OT is also associated with aggression, social selectivity, and reduced affiliation. Female meadow voles form social preferences for familiar same-sex peers under short, winter...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2016.02.025
更新日期：2016-06-01 00:00:00
abstract：:In previous studies it was shown that the tricyclic antidepressant desimipramine (DMI) had different stimulatory effects on growth hormone (GH), prolactin (PRL), ACTH and cortisol secretion in healthy subjects, depending on the mode of administration. The present study examined the effects following i.v. administratio...
journal_title：Psychoneuroendocrinology
pub_type： 临床试验,杂志文章
doi：10.1016/0306-4530(85)90042-3
更新日期：1985-01-01 00:00:00
abstract：:The association between SES and health is well established; however, only a handful of studies have investigated the relationship between SES and daily cortisol parameters. Further, within this small literature, virtually no studies have looked at psychological factors that might mitigate this relationship. In this st...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2015.06.010
更新日期：2015-10-01 00:00:00
abstract：:In a controlled cross-over design study performed with 14 female subjects, serum hormone levels, the EEG and a number of performance tests were recorded during spontaneous and oral contraceptive-controlled menstrual cycles. The mean alpha-frequency showed cyclic changes, i.e. slower alpha-waves during the follicular p...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/0306-4530(82)90057-9
更新日期：1982-01-01 00:00:00
abstract：:Cardiometabolic diseases are the main contributor of reduced life expectancy in patients with schizophrenia. It is now widely accepted that antipsychotic treatment plays an important role in the development of obesity and its consequences. However, some intrinsic mechanisms need to be taken into consideration. One of ...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章,评审
doi：10.1016/j.psyneuen.2020.104744
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:The main aim of this exploratory study was to assess whether salivary α-amylase (sAA) and salivary cortisol levels would be positively modulated by sleep-focused mind-body interventions in female and male cancer survivors. METHODS:We conducted a randomized controlled trial in which 57 cancer survivors with s...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psyneuen.2012.12.021
更新日期：2013-09-01 00:00:00
abstract：:Sex differences in self-control become apparent during preschool years. Girls are better able to delay their gratification and show less attention problems and overactive behavior than boys. In this context, organizational effects of gonadal steroids affecting the neural circuitry underlying self-control could be resp...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2019.02.014
更新日期：2019-06-01 00:00:00
abstract：:Anorexia nervosa is mostly seen in adolescent females, although the gender-differentiation mechanism is unclear. Corticotropin-releasing factor (CRF), a key peptide for stress responses such as inhibition of food intake, increases in arousal and locomotor activity, and gonadal dysfunction, is thought to be involved in...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2008.09.003
更新日期：2009-02-01 00:00:00
abstract：:Inconsistent findings have been found on the relation between oxytocin levels and psychopathy or callous-unemotional (CU) traits in humans, potentially because the role of trauma in oxytocin secretion and the distinction between primary and secondary psychopathy have been overlooked so far. Primary psychopathy has a s...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2018.11.040
更新日期：2019-04-01 00:00:00
abstract：:Since hypnosis was popularly recognized in the nineteenth century, the phenomenon of hypnotizability has remained poorly understood. The capacity to increase hypnotizability has important implications because it may increase the number of people who can benefit from hypnotic interventions for psychological and medical...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/j.psyneuen.2011.05.010
更新日期：2012-01-01 00:00:00
abstract：:The possible participation of the endogenous opioid system (EOS) in the negative feedback of the hypothalamic-pituitary-adrenal axis (HPA-a) activated by low doses (1 mg) of dexamethasone (Dex) was investigated. Ten male healthy subjects (mean age 31.5 +/- 1.9 SEM) were studied on 2 separate days, in a double-blind, c...
journal_title：Psychoneuroendocrinology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0306-4530(98)00002-x
更新日期：1998-05-01 00:00:00
abstract：:There is limited information on the relation between age-related changes in pituitary-gonadal function and sleep physiology in older men. In this cross-sectional study of 67 healthy volunteers free from sleep complaints, aged 45-75 yr, we (1) assessed peak fluctuations and hourly variations in plasma testosterone, LH ...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/0306-4530(92)90018-3
更新日期：1992-11-01 00:00:00
abstract：:The time course of hormone concentrations in response to a stimulus can be characterized with kinetic methods to express rates of hormone release and elimination, total amount of hormone release and expected best times for blood sampling. Routine application of kinetic methods should increase the sensitivity and appli...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/0306-4530(87)90066-7
更新日期：1987-01-01 00:00:00
abstract：:Changes in blood pressure (BP), plasma norepinephrine (NE), serum prolactin (PRL), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) associated with infusions of two thyrotropin-releasing hormone (TRH) doses (0.1 mg, 0.5 mg) were examined in 10 men with early-onset Alzheimer's disease (AD) and nine norm...
journal_title：Psychoneuroendocrinology
pub_type： 杂志文章
doi：10.1016/0306-4530(89)90033-4
更新日期：1989-01-01 00:00:00
abstract：:The cortisol rise after awakening (CAR) is a frequently applied measure of pituitary-adrenal activity. This measure seems to reflect the acrophase of the diurnal cycle and can easily be assessed in saliva samples, collected by the proband or patient under real life conditions. Since different state and trait factors a...
journal_title：Psychoneuroendocrinology
pub_type： 临床试验,杂志文章
doi：10.1016/j.psyneuen.2006.10.005
更新日期：2007-01-01 00:00:00
