当前位置： SCI文献检索 > PSYCHONEUROENDOCRINOLOGY期刊下所有文献 > Adolescent caffeine consumption increases adulthood anxiety-related behavior and modifies neuroendocrine signaling.

Adolescent caffeine consumption increases adulthood anxiety-related behavior and modifies neuroendocrine signaling.

Abstract：

:Caffeine is a commonly used psychoactive substance and consumption by children and adolescents continues to rise. Here, we examine the lasting effects of adolescent caffeine consumption on anxiety-related behaviors and several neuroendocrine measures in adulthood. Adolescent male Sprague-Dawley rats consumed caffeine (0.3g/L) for 28 consecutive days from postnatal day 28 (P28) to P55. Age-matched control rats consumed water. Behavioral testing for anxiety-related behavior began in adulthood (P62) 7 days after removal of caffeine. Adolescent caffeine consumption enhanced anxiety-related behavior in an open field, social interaction test, and elevated plus maze. Similar caffeine consumption in adult rats did not alter anxiety-related behavior after caffeine removal. Characterization of neuroendocrine measures was next assessed to determine whether the changes in anxiety were associated with modifications in the HPA axis. Blood plasma levels of corticosterone (CORT) were assessed throughout the caffeine consumption procedure in adolescent rats. Adolescent caffeine consumption elevated plasma CORT 24h after initiation of caffeine consumption that normalized over the course of the 28-day consumption procedure. CORT levels were also elevated 24h after caffeine removal and remained elevated for 7 days. Despite elevated basal CORT in adult rats that consumed caffeine during adolescence, the adrenocorticotropic hormone (ACTH) and CORT response to placement on an elevated pedestal (a mild stressor) was significantly blunted. Lastly, we assessed changes in basal and stress-induced c-fos and corticotropin-releasing factor (Crf) mRNA expression in brain tissue collected at 7 days withdrawal from adolescent caffeine. Adolescent caffeine consumption increased basal c-fos mRNA in the paraventricular nucleus of the hypothalamus. Adolescent caffeine consumption had no other effects on the basal or stress-induced c-fos mRNA changes. Caffeine consumption during adolescence increased basal Crf mRNA in the central nucleus of the amygdala, but no additional effects of stress or caffeine consumption were observed in other brain regions. Together these findings suggest that adolescent caffeine consumption may increase vulnerability to psychiatric disorders including anxiety-related disorders, and this vulnerability may result from dysregulation of the neuroendocrine stress response system.

journal_name

Psychoneuroendocrinology

journal_title

Psychoneuroendocrinology

authors

O'Neill CE,Newsom RJ,Stafford J,Scott T,Archuleta S,Levis SC,Spencer RL,Campeau S,Bachtell RK

doi

10.1016/j.psyneuen.2016.01.030

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

40-50

eissn

0306-4530

issn

1873-3360

pii

S0306-4530(16)30029-4

journal_volume

67

pub_type

杂志文章

相关文献

PSYCHONEUROENDOCRINOLOGY文献大全
  • Role of stress in the exacerbation of chronic illness: effects of clonidine administration on blood pressure and plasma norepinephrine, cortisol, growth hormone and prolactin concentrations.

    abstract：:Systolic blood pressure (SBP), diastolic blood pressure (DBP), and plasma norepinephrine (NE), cortisol (CRT), growth hormone (GH) and prolactin (PRL) were studied before and after clonidine (2.5 micrograms/kg i.m.) administration in 193 chronic severely ill patients and 193 normal subjects matched by age and sex. Dur...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(87)90042-4

    authors： Lechin F,van der Dijs B,Jackubowicz D,Camero RE,Lechin S,Villa S,Reinfeld B,Lechin ME

    更新日期：1987-01-01 00:00:00

  • Maternal cortisol output in pregnancy and newborn telomere length: Evidence for sex-specific effects.

    abstract：:Newborn telomere length is a potential biomarker of the effects of maternal-fetal processes on offspring long-term health. A number of maternal psychosocial and environmental factors in pregnancy (e.g., stress, health, socioeconomic status) have been associated with shortened telomere length at birth. The physiologica...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2018.12.222

    authors： Bosquet Enlow M,Sideridis G,Bollati V,Hoxha M,Hacker MR,Wright RJ

    更新日期：2019-04-01 00:00:00

  • Cortisol circadian rhythms and response to stress in children with autism.

    abstract：BACKGROUND:Autism is a severe neurodevelopmental disorder characterized by impairment in communication, social interaction, repetitive behaviors and difficulty adapting to novel experiences. The Hypothalamic-Pituitary-Adrenocortical (HPA) system responds consistently to perceived novel or unfamiliar situations and can ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2005.05.011

    authors： Corbett BA,Mendoza S,Abdullah M,Wegelin JA,Levine S

    更新日期：2006-01-01 00:00:00

  • Psychological stress and cortisol during pregnancy: An ecological momentary assessment (EMA)-Based within- and between-person analysis.

    abstract：BACKGROUND:Although the linkage between psychological stress and cortisol is believed to mediate the association of stress with health outcomes, several studies have been unable to demonstrate this association. We suggest this inability may be a consequence of limitations in the measurement approach and/or reliance on ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2020.104848

    authors： Lazarides C,Ward EB,Buss C,Chen WP,Voelkle MC,Gillen DL,Wadhwa PD,Entringer S

    更新日期：2020-11-01 00:00:00

  • Hypertonic saline infusion increases plasma norepinephrine concentrations in normal men.

    abstract：:We recently demonstrated in patients with panic disorder that hypertonic saline infusion induces acute panic with the same frequency and intensity as the standard hypertonic sodium lactate infusion. We now report the effects in normal men of hypertonic saline infusion on neuroendocrine systems possibly relevant to pan...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(93)90061-o

    authors： Peskind ER,Radant A,Dobie DJ,Hughes J,Wilkinson CW,Sikkema C,Veith RC,Dorsa DM,Raskind MA

    更新日期：1993-01-01 00:00:00

  • Childhood adversity and cortisol habituation to repeated stress in adulthood.

    abstract：BACKGROUND:Childhood adversity is a robust predictor of poor health outcomes in adulthood and hypothalamic-pituitary-adrenocortical (HPA) axis dysfunction may be a key mechanism explaining this association. However, little is known about the influence childhood adversity may exhibit on adult HPA axis habituation (i.e.,...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2020.105118

    authors： Appelmann HM,Manigault AW,Shorey RC,Zoccola PM

    更新日期：2020-12-24 00:00:00

  • Testosterone shifts the balance between sensitivity for punishment and reward in healthy young women.

    abstract：:Animal research has demonstrated reductions in punishment sensitivity and enhanced reward dependency after testosterone administration. In humans, elevated levels of testosterone have been associated with violent and antisocial behavior. Interestingly, extreme forms of violent and antisocial behavior can be observed i...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.psyneuen.2003.08.007

    authors： van Honk J,Schutter DJ,Hermans EJ,Putman P,Tuiten A,Koppeschaar H

    更新日期：2004-08-01 00:00:00

  • Interleukin-1 receptor type 1-deficient mice fail to develop social stress-associated glucocorticoid resistance in the spleen.

    abstract：:Frequent or chronic stress as a result of repeated or persistent exposure to social challenges has been shown to affect the glucocorticoid (GC) responsiveness of immune cells in mice. Lipopolysaccharide-stimulated splenocytes of mice that were repeatedly subjected to social disruption were less sensitive to the anti-i...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2007.10.007

    authors： Engler H,Bailey MT,Engler A,Stiner-Jones LM,Quan N,Sheridan JF

    更新日期：2008-01-01 00:00:00

  • Maternal serum concentrations of BDNF and depression in the perinatal period.

    abstract：:There is accumulating evidence that a deficiency in brain-derived neurotrophic factor (BDNF) plays a critical role in the pathophysiology of depression. This is in line with the postulate that low BDNF levels in serum are associated with depression. However, the regulation of maternal BDNF serum levels in the perinata...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2005.09.003

    authors： Lommatzsch M,Hornych K,Zingler C,Schuff-Werner P,Höppner J,Virchow JC

    更新日期：2006-04-01 00:00:00

  • Salivary alpha-amylase as a non-invasive biomarker for the sympathetic nervous system: current state of research.

    abstract：:Development of new biomarkers is a constantly evolving field of research endeavor in psychoneuroendocrinology. Salivary biomarkers have received special attention since they are readily accessible and easily obtained. Salivary alpha-amylase (sAA) has been proposed as a sensitive biomarker for stress-related changes in...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/j.psyneuen.2009.01.014

    authors： Nater UM,Rohleder N

    更新日期：2009-05-01 00:00:00

  • Oxytocin sharpens self-other perceptual boundary.

    abstract：:Recent cross-species research has demonstrated that the neurohormone oxytocin plays a key role in social interaction and cognitive processing of others' emotions. Whereas oxytocin has been shown to influence social approach, trust, and bond formation, a potential role of the oxytocinergic system in blurring or enhanci...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2013.08.010

    authors： Colonnello V,Chen FS,Panksepp J,Heinrichs M

    更新日期：2013-12-01 00:00:00

  • Latent trait cortisol (LTC) during pregnancy: Composition, continuity, change, and concomitants.

    abstract：:Individual differences in the activity of the hypothalamic pituitary adrenal (HPA) axis are often operationalized using summary measures of cortisol that are taken to represent stable individual differences. Here we extend our understanding of a novel latent variable approach to latent trait cortisol (LTC) as a measur...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2015.08.009

    authors： Giesbrecht GF,Bryce CI,Letourneau N,Granger DA,APrON study Team.

    更新日期：2015-12-01 00:00:00

  • Influence of marital status on testosterone levels-A ten year follow-up of 1113 men.

    abstract：:Based on a large population of 1113 men aged 30-60 at baseline (mean: 44.1 years, standard deviation: 10.5), we investigated whether intra-individual changes in testosterone (T) and related reproductive hormones during a ten year period were dependent of marital status at baseline and follow-up. The studied men were p...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2017.03.010

    authors： Holmboe SA,Priskorn L,Jørgensen N,Skakkebaek NE,Linneberg A,Juul A,Andersson AM

    更新日期：2017-06-01 00:00:00

  • Immobilization-induced stress decreases lipogenesis in sebaceous glands as well as plasma testosterone levels in male Syrian hamsters.

    abstract：:The effects of immobilization-induced stress on plasma testosterone levels and lipogenesis in the sebaceous gland were examined in male Syrian hamsters. To induce immobilization stress, the animals were placed in the prone position and wrapped with flexible steel wire gauze at room temperature. Plasma testosterone lev...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(94)00055-f

    authors： Tsuchiya T,Horii I

    更新日期：1995-01-01 00:00:00

  • Multiple hormonal responses to morphine: relationship to diagnosis and dexamethasone suppression.

    abstract：:Plasma cortisol, prolactin (PRL), growth hormone (GH), and thyroid stimulating hormone (TSH) responses to intravenous morphine (0.1 mg/kg body weight) were investigated in five healthy women and 22 female psychiatric inpatients (eight with major depression, 12 with schizophrenia and two with personality disorders) dur...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(87)90016-3

    authors： Banki CM,Arato M

    更新日期：1987-01-01 00:00:00

  • Blunted basal corticosterone pulsatility predicts post-exposure susceptibility to PTSD phenotype in rats.

    abstract：:The basal activity of the hypothalamic-pituitary-adrenal axis is highly dynamic and is characterized by both circadian and ultradian (pulsatile) patterns of hormone secretion. Pulsatility of glucocorticoids has been determined to be critical for optimal transcriptional, neuroendocrine, and behavioral responses. We use...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2017.09.023

    authors： Danan D,Matar MA,Kaplan Z,Zohar J,Cohen H

    更新日期：2018-01-01 00:00:00

  • Influence of pimozide on hypothalamo-pituitary function in children with behavioral disorders.

    abstract：:Hypothalamo-pituitary functions were examined in thirteen children with behavioral disorders (six with hyperkinesia, four with autism, two with tic and one with schizophrenia) before and during treatment with pimozide, an antidopaminergic drug. The mean (+/- S.E.M.) basal serum PRL level (24.5 +/- 4.2 ng/ml) during pi...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(84)90020-9

    authors： Suwa S,Naruse H,Ohura T,Tsuruhara T,Takesada M,Yamazaki K,Mikuni M

    更新日期：1984-01-01 00:00:00

  • Prenatal SSRI exposure alters neonatal corticosteroid binding globulin, infant cortisol levels, and emerging HPA function.

    abstract：BACKGROUND:Serotonin influences the development of the hypothalamic-pituitary-adrenal (HPA) system; therefore prenatal exposure to selective serotonin reuptake inhibitor antidepressants (SSRIs) may alter HPA axis development and function. To address this, prenatal exposure to SSRIs and maternal mood were examined in re...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.psyneuen.2011.11.011

    authors： Pawluski JL,Brain UM,Underhill CM,Hammond GL,Oberlander TF

    更新日期：2012-07-01 00:00:00

  • Stress management, leukocyte transcriptional changes and breast cancer recurrence in a randomized trial: An exploratory analysis.

    abstract：PURPOSE:Cognitive behavioral stress management (CBSM) is an empirically-validated group-based psychosocial intervention. CBSM is related to decreased self-reported indicators of psychological adversity during breast cancer treatment and greater disease-free survival (DFS) vs. a control condition. This study examined re...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.psyneuen.2016.09.012

    authors： Antoni MH,Bouchard LC,Jacobs JM,Lechner SC,Jutagir DR,Gudenkauf LM,Carver CS,Lutgendorf S,Cole SW,Lippman M,Blomberg BB

    更新日期：2016-12-01 00:00:00

  • Chronic anabolic-androgenic steroid treatment during adolescence increases anterior hypothalamic vasopressin and aggression in intact hamsters.

    abstract：:The present study examines the hypothesis that exposure to anabolic-androgenic steroids (AAS) during adolescent development predisposes hamsters to heightened levels of aggressive behavior by influencing the anterior hypothalamic-arginine vasopressin (AH-AVP) neural system. To test this, adolescent male hamsters (Meso...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/s0306-4530(99)00057-8

    authors： Harrison RJ,Connor DF,Nowak C,Nash K,Melloni RH Jr

    更新日期：2000-05-01 00:00:00

  • Cognitive effects and antipsychotic treatment.

    abstract：:Cognitive impairment has long been recognized as central to the abnormalities that occur in schizophrenia, since neurocognitive deficits are predictive of a number of outcome indices, and they pose a significant obstacle to any attempts at social rehabilitation. This raises the possibility that treatments producing im...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/s0306-4530(02)00115-4

    authors： Kasper S,Resinger E

    更新日期：2003-01-01 00:00:00

  • Differential responses in prolactin levels induced by naloxone in humans.

    abstract：:The plasma prolactin (PRL) response to the opiate antagonist naloxone was tested in drug-free healthy volunteers (10 men, 18 regularly menstruating women who were in the late follicular phase of their ovarian cycles, and seven post-menopausal women). Naloxone hydrochloride (2 mg intravenous bolus) and placebo (normal ...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/0306-4530(85)90058-7

    authors： Steardo L,Monteleone P,Tamminga CA,Canonico PL,Denman D,Scapagnini U,Chase TN

    更新日期：1985-01-01 00:00:00

  • Neuroanatomical pathways linking vision and olfaction in mammals.

    abstract：:Retinal projections to several telencephalic structures have been demonstrated in a wide range of mammalian species following intraocular injections of tritiated amino acids and cholera toxin subunit-B conjugated to horseradish peroxidase. Since these regions are also innervated by olfactory fibers, we investigated th...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(94)90046-9

    authors： Cooper HM,Parvopassu F,Herbin M,Magnin M

    更新日期：1994-01-01 00:00:00

  • Seasonal variation in salivary cortisol but not symptoms of depression and trait anxiety in pregnant women undergoing an elective caesarean section.

    abstract：OBJECTIVES:Seasonal changes in mood and behaviour are commonly reported in the general population but considerably less is known regarding seasonality and pregnancy. This study investigated the relationship between seasons and depression and anxiety symptoms, salivary cortisol concentrations, custom birthweight centile...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2019.05.029

    authors： Garay SM,Savory KA,Sumption LA,Penketh RJA,Jones IR,Janssen AB,John RM

    更新日期：2019-10-01 00:00:00

  • Early childhood adversity and HPA axis activity in adulthood:The importance of considering minimal age at exposure.

    abstract：:Early adversity (EA) modulates stress hormone secretion in mixed directions. The Accumulation Model suggests that the number of EA predicts patterns of cortisol dysregulations, while the Life Cycle Model of Stress highlights the importance of considering the timing at which EA began, given that brain regions sensitive...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2020.105042

    authors： Raymond C,Marin MF,Wolosianski V,Journault AA,Longpré C,Leclaire S,Cernik R,Juster RP,Lupien SJ

    更新日期：2020-11-22 00:00:00

  • Autoimmune thyroid disease, left-handedness, and developmental dyslexia.

    abstract：:Autoimmune thyroid disease (ATD) (Graves' disease and Hashimoto's thyroiditis) has been one of a number of autoimmune diseases possibly associated with left-handedness, mixed dominance, and learning disability. In the present study, 74 men with ATD were compared to 24 control men with non-ATD. An increased frequency o...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(92)90080-q

    authors： Wood LC,Cooper DS

    更新日期：1992-01-01 00:00:00

  • Stress-induced release of matrix metalloproteinase-9 in patients with coronary artery disease: The possible influence of cortisol.

    abstract：:Stress and inflammation are both important risk factors for coronary artery disease (CAD). However, the susceptibility to stress-induced inflammation and its determinants have been little explored in patients with CAD. Here, our aim was to study the stress-induced inflammatory response, more precisely the early releas...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2016.07.219

    authors： Lundberg AK,Jönsson S,Stenmark J,Kristenson M,Jonasson L

    更新日期：2016-11-01 00:00:00

  • Cerebrospinal fluid and plasma testosterone levels in post-traumatic stress disorder and tobacco dependence.

    abstract：BACKGROUND:Little is known about the relationship between endogenous central nervous system (CNS) testosterone and any psychiatric syndrome. The goal of this study was to screen for potential abnormalities in CNS testosterone levels in patients with post-traumatic stress disorder (PTSD) and/or tobacco dependence. METH...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0306-4530(00)00052-4

    authors： Mulchahey JJ,Ekhator NN,Zhang H,Kasckow JW,Baker DG,Geracioti TD Jr

    更新日期：2001-04-01 00:00:00

  • Emerging role of the P2X7-NLRP3-IL1β pathway in mood disorders.

    abstract：:The science of neuroimmunopsychiatry has evolved rapidly in the last few years with the hope of tackling the unmet need in mood disorders. This article focuses on an inflammatory pathway, highly conserved in myeloid cells that may play a role in neuroinflammatory disorders including depression. Within the brain tissue...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/j.psyneuen.2018.08.015

    authors： Bhattacharya A,Jones DNC

    更新日期：2018-12-01 00:00:00

  • Effects of clozapine and olanzapine on cytokine systems are closely linked to weight gain and drug-induced fever.

    abstract：:The second generation antipsychotics clozapine and olanzapine are known to cause weight gain. However, only clozapine is associated with drug-induced fever. Cytokines have been linked to the induction of both weight gain and drug-induced fever. We investigated these potential side effects of clozapine and olanzapine a...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.psyneuen.2008.08.016

    authors： Kluge M,Schuld A,Schacht A,Himmerich H,Dalal MA,Wehmeier PM,Hinze-Selch D,Kraus T,Dittmann RW,Pollmächer T

    更新日期：2009-01-01 00:00:00