Abstract:
:The concentrations of pregnanediol-3-glucuronide (PGD) and pregnanolone (PN) were measured in daily morning urine specimens from 66 infertile women (40 with varying degrees of endometriosis and 26 control subjects) and correlated with daily changes in basal body temperature (BBT) and with midluteal levels of serum progesterone (P). PN and BBT rose at midcycle in women with endometriosis, as expected, indicating secretion of some P at that time. However, PGD, the major endpoint of P metabolism, was delayed in its excretion. Endometrial biopsies were similarly delayed (out of phase) in women with endometriosis, and a significantly higher incidence of follicular luteinization was seen. It appears that while P secretion begins at midcycle, the bulk of P secretion is delayed, perhaps because of the process of follicular luteinization, and that a shortened functional luteal phase thus exists in women with endometriosis.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Cheesman KL,Cheesman SD,Chatterton RT Jr,Cohen MRsubject
Has Abstractpub_date
1983-11-01 00:00:00pages
590-5issue
5eissn
0015-0282issn
1556-5653pii
S0015-0282(16)47414-5journal_volume
40pub_type
杂志文章abstract:OBJECTIVE:To assess the potential effect of bisphenol A (BPA), triclosan (TCS), and phthalates on women's fecundity, as measured by time to pregnancy (TTP). DESIGN:Pregnancy-based retrospective TTP study. SETTING:Not applicable. PATIENT(S):A total of 2,001 women during the first trimester of pregnancy recruited betw...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.01.005
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:To test the effects of steroid-containing media such as follicular fluid (FF) and serum and of steroid-free but human protein-rich medium on hyperactivation (HA) of human spermatozoa with and without a preincubation period. DESIGN:Analysis of HA using a computer-aided sperm analysis system. SETTING:Academic...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)57191-x
更新日期:1994-12-01 00:00:00
abstract::Websites for Society for Assisted Reproductive Technology-affiliated clinics fail to meet most American Medical Association health information guidelines. Professional organizations in reproductive medicine need to standardize the accuracy and appropriateness of online reproductive health information. ...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2004.11.024
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:Mutation within androgen receptor (AR) can be seen. Presently, prediction of protein nanostructure and function is a great challenge in the proteomics and structural genomics era. To identify the points vulnerable to mutation is a new trend to expand the knowledge on disorders in genomic and proteomic level o...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.06.089
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To provide an up-to-date comprehensive review of published data on laparoscopic methods of ovulation induction in the polycystic ovary syndrome (PCOS). Areas to be considered include the historical background of these procedures, their outcomes as reported in the literature, and their potential adverse effect...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(16)57408-1
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between female cystic fibrosis (CF) carrier status and in vitro fertilization (IVF) response and outcomes. The presence of cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations in male carriers has been associated with infertility, yet possible adverse effects o...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2014.07.1234
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To evaluate endometrial adhesion and invasion of peritoneal mesothelium. DESIGN:Descriptive study using confocal laser-scanning microscopy. SETTING:University-based laboratory. PATIENT(S):Women undergoing surgery for benign conditions. INTERVENTION(S):Fluorescence-labeled peritoneal mesothelial cells (PMC...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(02)04834-3
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:To achieve maximum post-thaw survival of frozen embryos. DESIGN:Historical controlled study. SETTING:Hospital-based fertility center. PATIENT(S):One hundred forty-five patients whose embryos were frozen and thawed according to the standard method, and 56 patients whose embryos were frozen and thawed accord...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.04.054
更新日期:2005-11-01 00:00:00
abstract::In an attempt to improve the motility of thawed spermatozoa after 1 week of its being frozen, we treated ten normal semen samples with 16.7 nmol relaxin and 6 mmol caffeine. Motility and grade of forward progression were examined after thawing. Caffeine significantly improved motility of spermatozoa. Relaxin, when add...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)48868-0
更新日期:1985-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the ovarian reserve changes after laparoscopic cystectomy, we prospectively evaluated pre- and postoperative serum anti-Müllerian hormone (AMH) level, and ovarian volumes. DESIGN:Prospective longitudinal study. SETTING:University Hospital. PATIENT(S):Twenty women with benign ovarian masses part...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.02.022
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the potential clinical application of Raman spectroscopy (RS) as a tool that may identify spermatogenesis within human seminiferous tubules. DESIGN:RS scanning of human testicular tissue at different maturational stages; immunohistochemistry study and metabolomic analysis of nonobstructive azoosp...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2014.03.035
更新日期:2014-07-01 00:00:00
abstract::With advances in cancer therapies, survival rates in prepubescent patients have steadily increased. However, a number of these surviving patients have been rendered sterile owing to their rigorous oncologic treatment regimens. In addition to cancer treatments, men and women, who are genetically fertile, can become inf...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2013.11.025
更新日期:2014-01-01 00:00:00
abstract::This study was conducted to investigate the effects of unilateral cryptorchidism on androgen production and testicular maturation. Experimental cryptorchidism was produced in small and large prepuberal guinea pigs by forcing the testis to remain in the abdomen for a period of 30 days. Small prepuberal animals, which d...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1975-07-01 00:00:00
abstract:OBJECTIVE:To obtain proof-of-concept that locally produced anti-inflammatory steroids suppress ovulation-associated extracellular matrix proteases in human ovarian surface epithelial (OSE) cells. DESIGN:Primary OSE cell cultures treated with interleukin-1alpha (IL-1alpha) (500 pg/mL) as proxy for inflammation, with/wi...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.06.040
更新日期:2009-08-01 00:00:00
abstract::Nonsurgical recovery of a preimplantation conceptus from the uterus of a fertile donor woman with transfer to an infertile recipient woman and subsequent pregnancy has been described previously. In this report, we describe the performance of 56 nonsurgical uterine lavages, recovery of 23 ova, and transfer of 17 ova wi...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:To report the successful and feasible use of transperineal fine needle aspiration of seminal vesicles (FNASV) for sperm retrieval in obstructive azoospermia. DESIGN:Case report. SETTING:Outpatient care in institutional clinic. PATIENT(S):A 31-year-old man with obstructive azoospermia due to a middle prosta...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.03.069
更新日期:2006-12-01 00:00:00
abstract::We have examined the effects of prolactin (PRL) on progesterone (P) and estradiol (E2) synthesis by cells obtained from human corpora lutea of early and midluteal phases. The cells were cultured in the presence or absence of low (200 mIU/l) or high levels (1000 mIU/l) of PRL. Basal P, but not E2 was significantly (P l...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1987-06-01 00:00:00
abstract:OBJECTIVE:To review the association between autoimmunity and reproductive failure. DESIGN:A MEDLINE search done from 1965 to 1996. More than 300 original and review articles were evaluated, from which the most relevant were selected. RESULT(S):Autoimmune processes now are accepted widely as one of the possible mechan...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(97)81351-9
更新日期:1997-04-01 00:00:00
abstract::Although fibroids are common benign tumors, their impact on women's quality of life can be considerable. The most frequent symptoms are uterine bleeding, resulting in anemia, and pelvic pain. Fibroids can be of genetic or hormonal origin or arise from intrauterine events. Current options for medical treatment include ...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2014.07.1238
更新日期:2014-09-01 00:00:00
abstract::The effectiveness of antiestrogens and progestins in the inhibition of capacitation in the rabbit uterus and oviduct was studied. The agents tested were 8 mg/day nafoxidine HCL (NHCL), 4 mg/day fluoxymesterone (FM), 4 and 20 mg/day clomiphene citrate (CC), 8 mg/day testosterone (T), 8 mg/day dydrogesterone (D) 4 and ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1972-03-01 00:00:00
abstract::This study was undertaken to determine whether women with endometriosis have altered protein, progesterone (P), and protease inhibitor concentrations in their uterine fluid and peritoneal fluid (PF) compared with controls at different phases of the menstrual cycle. Uterine flushings (UFs), PF, and blood were obtained ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)49994-2
更新日期:1987-02-01 00:00:00
abstract::Danazol and gestrinone are effective drugs in the treatment of endometriosis. Their mechanism of action remains uncertain, but may be related to their androgenic activity. The authors examined the effect of danazol on human endometrial cells cultured in vitro, its two major metabolites, ethisterone and 2 hydroxymethyl...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)59706-4
更新日期:1988-02-01 00:00:00
abstract::The glycolytic enzymes, lactate dehydrogenase (LDH), glucose-6-phosphate dehydrogenase, and hexokinase in cervical mucus of 96 ovulatory women were serially measured daily during the menstrual cycle. Among all of the enzymes, the cyclic changes in LDH activity were the most significant, being high during the prolifera...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)44533-4
更新日期:1980-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the predictive value of seminal inhibin B and anti-Müllerian hormone (AMH) on the outcome of testicular sperm extraction (TESE) in patients with nonobstructive azoospermia. DESIGN:Prospective study. SETTING:Reproductive biology department. PATIENT(S):Forty-seven normospermic, 28 oligozoospermic...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.03.032
更新日期:2008-02-01 00:00:00
abstract::In a qualitative interview study of 77 families with stored frozen embryos, we found that while embryo disposition decision making was influenced by individual life circumstances, embryo quantity/quality, personal values, embryo conceptualization, and clinic information, it was a stepwise process that could be represe...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.06.027
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:To compare the pregnancy outcomes of twin pregnancies following early transvaginal multifetal pregnancy reduction (MPR) with nonreduced twin gestations. DESIGN:Prospective cohort study. SETTING:Two tertiary medical centers. PATIENT(S):A cohort of 77 multiple pregnancies after reduction to twins and 78 dich...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
doi:10.1016/j.fertnstert.2014.01.032
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:Both pronuclear morphology and early zygote cleavage have been used in combination with day 3 criteria to predict implantation and pregnancy. However, in routine practice, it is impractical to use both these criteria to select embryos on day 3. The objective of the present study was to find which of the two c...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2005.07.1319
更新日期:2006-02-01 00:00:00
abstract::Human testes, removed in treating patients for prostatic carcinoma, were used. Tissues were homogenized and incubated in vitro with labeled progesterone and 2 different antiovulatories, lynestrenol (17alpha-ethin yl-17beta-hydroxy-estr-4-one) and MK 665 (17alpha-chloroethinyl-19-nor-4 ,9(10)-androstadiene-17beta-ol-...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)36309-9
更新日期:1967-05-01 00:00:00
abstract::The presence of ovarian cysts may compromise the success of in vitro fertilization (IVF) and gamete intrafallopian transfer (GIFT). We prospectively studied 212 consecutive ovulation induction cycles in 120 patients for IVF and/or GIFT. A baseline cyst was defined as any intraovarian cystic structure greater than or e...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54123-5
更新日期:1991-02-01 00:00:00
abstract::Several studies have shown a decrease in uterine and/or leiomyoma volume when treated with leuprolide acetate (LA), a widely used gonadotropin-releasing hormone agonist. The mechanism by which these changes occur is unknown. In this study, the histopathological slides of 31 women of reproductive age who underwent hyst...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53937-5
更新日期:1990-11-01 00:00:00