[Mezlocillin in the antibiotic therapy of severe bacterial infections in visceral surgery].

Abstract:

:Fifty-six patients suffering from severe and very severe bacterial infections received additional antibacterial treatment with mezlocillin following abdominal or chest surgery. There were 18 intestinal-peritoneal infections, 15 pleuropulmonary infections, seven patients with sepsis, six localized abscesses and ten patients receiving perioperative application. In 36 patients treatment had to be initiated before the pathogens had been identified. Twenty patients received mezlocillin alone and 37 in combination with an aminoglycoside. The clinical course and laboratory data were recorded while the patients were receiving antibiotic therapy. In 43 of the 56 patients, most of whom were suffering from mixed infections caused by anaerobes and aerobes or from fecal infections, a cure without complications could be achieved. In six patients a generalized infection was reduced to a local one which could be cured. Eight patients died, six of their surgical primary disease and two of septic complications. Apart from four instances of phlebitis at the site of the infusion, no side-effects resulted from our antibiotic therapy.

journal_name

Infection

journal_title

Infection

authors

Amgwerd R,Rauh G,Sonnabend W

doi

10.1007/BF01640656

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

S131-7

eissn

0300-8126

issn

1439-0973

journal_volume

10 Suppl 3

pub_type

杂志文章
  • Secretory non-pancreatic phopholipase A2 in severe sepsis: relation to endotoxin, cytokines and thromboxane B2.

    abstract::Circulatory secretory non-pancreatic phospholipase A2 (snp-PLA2) was measured prospectively at the onset (day 0) of severe sepsis in 52 patients as well as on day 1 and 2 in 25 patients, in order to answer two questions: 1) does the snp-PLA2 plasma concentration differ according to the type and severity of infection? ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01713312

    authors: Guidet B,Piot O,Masliah J,Barakett V,Maury E,Bereziat G,Offenstadt G

    更新日期:1996-03-01 00:00:00

  • Correction to: Mucormycosis in hospitalized patients at a tertiary care center in Lebanon: a case series.

    abstract::The spelling of the name "Ali Bazarbachi" was incorrect. ...

    journal_title:Infection

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s15010-018-1203-8

    authors: El Zein S,El-Sheikh J,Zakhem A,Ibrahim D,Bazarbachi A,Kanj SS

    更新日期:2018-12-01 00:00:00

  • Prevalence rates of viral hepatitis infections in refugee Kurds from Iraq and Turkey.

    abstract:BACKGROUND:Since little is known about the burden of viral hepatitis in Kurds, the prevalence of infection with hepatitis A virus (HAV), hepatitis E virus (HEV), hepatitis B virus (HBV) and hepatitis C virus (HCV) was investigated in a sample of refugee Kurds from Iraq and Turkey. PATIENTS AND METHODS:A cross-sectiona...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-002-3100-3

    authors: Chironna M,Germinario C,Lopalco PL,Carrozzini F,Barbuti S,Quarto M

    更新日期:2003-03-01 00:00:00

  • Mortality after bloodstream infections in allogeneic haematopoietic stem cell transplant (HSCT) recipients.

    abstract:PURPOSE:Bloodstream infections (BSIs) are frequent after allogeneic haematopoietic stem cell transplantation (HSCT). The aim of this study was to identify predictors of mortality after BSI in patients who undergo HSCT. METHODS:Patients who underwent HSCT between 1 January 2004 and 31 January 2008 and developed BSI dur...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0229-y

    authors: Mikulska M,Del Bono V,Bruzzi P,Raiola AM,Gualandi F,Van Lint MT,Bacigalupo A,Viscoli C

    更新日期:2012-06-01 00:00:00

  • TT virus infection and genotype distribution in blood donors and a group of patients from Turkey.

    abstract:BACKGROUND:TT virus (TTV) DNA has been found in a large proportion of patients with different forms of non-A-G hepatitis, however the clinical importance is unclear. We aimed to determine the genotypes of TTV isolates found in blood donors and different patient groups from the western part of Turkey. MATERIALS AND MET...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-002-2185-z

    authors: Erensoy S,Sayiner AA,Türkoğlu S,Canatan D,Akarca US,Sertöz R,Ozacar T,Batur Y,Badur S,Bilgiç A

    更新日期:2002-10-01 00:00:00

  • New fluoroquinolones in lower respiratory tract infections and emerging patterns of pneumococcal resistance.

    abstract::The increasing resistance of Streptococcus pneumoniae, the most important community respiratory pathogen, to beta-lactams and other first-line antimicrobial agents usually employed for the empirical treatment of lower respiratory tract infections has led to the inclusion, in several current guidelines, of a fluoroquin...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-005-4102-8

    authors: Ferrara AM

    更新日期:2005-06-01 00:00:00

  • Four-year experience with a recombinant hepatitis B vaccine.

    abstract::Three hundred and forty-three healthy adults were vaccinated with five different lots of recombinant hepatitis B vaccine. Three hundred and forty (99.1%) individuals produced antibodies against hepatitis B surface antigen (anti-HBs). Peak anti-HBs concentrations were significantly higher in females and younger individ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01646879

    authors: Jilg W,Schmidt M,Deinhardt F

    更新日期:1989-03-01 00:00:00

  • Incidence of Helicobacter pylori infection in a cohort of Italian military students.

    abstract::Prevalence and incidence of Helicobacter pylori infection among 250 Italian military students were studied using specific IgG antibodies. Subjects susceptible at enrollment were evaluated during a 10-month follow-up period, when two serum samples were collected after 5 and 10 months, respectively. Samples were also an...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF02561526

    authors: Biselli R,Fortini M,Matricardi PM,Stroffolini T,D'Amelio R

    更新日期:1999-05-01 00:00:00

  • Benefit and advantage to clinicians of a computer-assisted microbiological diagnosis and database system.

    abstract::Computer-assisted diagnostic systems may accelerate transmission of microbiological reports and facilitate evaluation of the epidemiological situation and thus improve the collaboration between microbiologists and clinicians. This possible benefit is demonstrated by four examples. It became evident that incidences of ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01646938

    authors: Manncke K,Heizmann W

    更新日期:1988-01-01 00:00:00

  • Cefotaxime: efficacy and tolerance in lower respiratory tract infections caused by gram-positive cocci.

    abstract::Cefotaxime is an effective antibiotic in lower respiratory tract infection caused by streptococci and staphylococci. There is a limited tendency to superinfections with Pseudomonas aeruginosa (1.5%) and there is a low incidence of side-effects. It is questionable whether there is really an urgent need for cefotaxime i...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644213

    authors: Lode H,Glatzel PD

    更新日期:1985-01-01 00:00:00

  • The effects of pretransplant conditioning, graft-versus-host disease and sepsis on the CRP levels in bone marrow transplantation.

    abstract::To evaluate the diagnostic utility of C-reactive protein (CRP) for the detection of sepsis in bone marrow transplantation, CRP levels were analyzed after pretransplant conditioning and variably combined in septic, focal or viral infections with graft-versus-host disease (GvHD) in 64 bone marrow recipients. The CRP lev...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01740812

    authors: Rintala E,Remes K,Salmi TT,Koskinen P,Nikoskelainen J

    更新日期:1997-11-01 00:00:00

  • Effectiveness of a multidimensional approach for prevention of ventilator-associated pneumonia in 11 adult intensive care units from 10 cities of Turkey: findings of the International Nosocomial Infection Control Consortium (INICC).

    abstract:PURPOSE:To evaluate the impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional approach on the reduction of ventilator-associated pneumonia (VAP) in adult patients hospitalized in 11 intensive care units (ICUs), from 10 hospitals, members of the INICC, in 10 cities of Turkey. METH...

    journal_title:Infection

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s15010-013-0407-1

    authors: Leblebicioglu H,Yalcin AN,Rosenthal VD,Koksal I,Sirmatel F,Unal S,Turgut H,Ozdemir D,Ersoz G,Uzun C,Ulusoy S,Esen S,Ulger F,Dilek A,Yilmaz H,Turhan O,Gunay N,Gumus E,Dursun O,Yýlmaz G,Kaya S,Ulusoy H,Cengiz M

    更新日期:2013-04-01 00:00:00

  • Ventriculitis caused by Klebsiella pneumoniae successfully treated with pefloxacin in a neonate.

    abstract::Pefloxacin was applied to a newborn suffering from ventriculitis caused by Klebsiella pneumoniae after failure of routine antibiotics. Treatment was successful. Blood and CSF levels were high, thus documenting good CSF penetration. In addition to this case report, a review of the literature regarding seven neonates wi...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01716707

    authors: Linder N,Dagan R,Kuint J,Keler N,Keren G,Reichman B

    更新日期:1994-05-01 00:00:00

  • Combination therapy with an aminoglycoside for Staphylococcus aureus endocarditis and/or persistent bacteremia is associated with a decreased rate of recurrent bacteremia: a cohort study.

    abstract:PURPOSE:Although limited data exist on the efficacy and potential risk of synergistic aminoglycoside therapy for persistent Staphylococcus aureus bacteremia and endocarditis, aminoglycosides are frequently used in clinical practice. METHODS:As our study population, we included subjects fulfilling the modified Duke cri...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0189-2

    authors: Lemonovich TL,Haynes K,Lautenbach E,Amorosa VK

    更新日期:2011-12-01 00:00:00

  • Socioeconomic impact on device-associated infections in limited-resource neonatal intensive care units: findings of the INICC.

    abstract:PURPOSE:To evaluate the impact of country socioeconomic status and hospital type on device-associated healthcare-associated infections (DA-HAIs) in neonatal intensive care units (NICUs). METHODS:Data were collected on DA-HAIs from September 2003 to February 2010 on 13,251 patients in 30 NICUs in 15 countries. DA-HAIs ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0136-2

    authors: Rosenthal VD,Lynch P,Jarvis WR,Khader IA,Richtmann R,Jaballah NB,Aygun C,Villamil-Gómez W,Dueñas L,Atencio-Espinoza T,Navoa-Ng JA,Pawar M,Sobreyra-Oropeza M,Barkat A,Mejía N,Yuet-Meng C,Apisarnthanarak A,International N

    更新日期:2011-10-01 00:00:00

  • Hepatitis with fibrin-ring granulomas.

    abstract::We describe a 66-year-old woman hospitalized with fever, fatigue and hepatopathy. In her medical history arterial hypertension (treated with propranolol and lisinopril), diabetes mellitus type 2 (no treatment before admission) and a gout arthropathy were noted wherefore a therapy with allopurinol 300 mg per day has be...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-007-6365-8

    authors: Khanlari B,Bodmer M,Terracciano L,Heim MH,Fluckiger U,Weisser M

    更新日期:2008-08-01 00:00:00

  • Anti-V3 loop spectrotype in HIV-infected individuals during zidovudine therapy.

    abstract::In order to investigate the role played by zidovudine (ZDV) as immune modulator, particularly on B-cell response, the anti-V3 loop spectrotype in 115 sera from 26 HIV-infected individuals was evaluated, prior to and during treatment with ZDV, by isoelectric focusing and reverse blotting (IEF-RB), a technique useful fo...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01781097

    authors: Biselli R,Del Bono V,Anselmo M,Canessa A,Mazzarello G,D'Amelio R,Bassetti D

    更新日期:1996-05-01 00:00:00

  • [In vitro effect of acylureido penicillins and mezlocillin on anaerobic sporeless gram-negative rods of genus Bacteroides].

    abstract::313 anaerobic gram-negative rods of the Bacteroides genus isolated from 295 clinical specimens were tested for their sensitivity to azlocillin and mezlocillin using the dilution method with agar plates. 25 mg/l of azlocillin inhibited 80.2% of the strains and the same concentration of mezlocillin inhibited 86.9%. The ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01640681

    authors: Höhne C

    更新日期:1982-01-01 00:00:00

  • Effect of 17 beta-estradiol on adherence of Escherichia coli to human endometrial stromal cells.

    abstract::The effect of 17 beta-estradiol on in vitro adherence of six strains of uropathic Escherichia coli to human endometrial stromal cells was examined. In contrast to the findings of earlier investigations using murine urogenital cells and malignant human urogenital cell lines, our studies showed no significant effect of ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01646885

    authors: Mackowiak PA,Goggans ML

    更新日期:1989-03-01 00:00:00

  • Comparative trial of trimethoprim and co-trimoxazole in recurrent urinary infections.

    abstract::Eighty-nine patients with a history of recurrent urinary infection who required immediate treatment for significant bacteriuria were treated with either trimethoprim (300 mg at night) or with the standard course of co-trimoxazole (two tablets 12-hourly) for seven days. Cure rates one week after the end of treatment we...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01640874

    authors: Brumfitt W,Hamilton-Miller JM,Ludlam H,Damjanovic V,Gargan R

    更新日期:1982-09-01 00:00:00

  • Susceptibility to HIV/AIDS: an individual characteristic we can measure?

    abstract::Susceptibility to HIV-1 infections is, beside other factors, determined by individual host genetic variants like HLA class I alleles, CCR5 and CCR2 variants and levels of CCR5 binding chemokines. A new approach to determine the individual risk of acquiring an HIV infection or to estimate the disease progression could ...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-005-6305-4

    authors: Jülg B,Goebel FD

    更新日期:2005-06-01 00:00:00

  • Promoting Global Research Excellence in Severe Sepsis (PROGRESS): lessons from an international sepsis registry.

    abstract:BACKGROUND:The PROGRESS Registry (Promoting Global Research Excellence in Severe Sepsis) was designed to provide comparative data reflecting everyday clinical practice, thereby allowing participating institutions to explore and benchmark medical interventions in severe sepsis. MATERIALS AND METHODS:PROGRESS was an int...

    journal_title:Infection

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s15010-008-8203-z

    authors: Beale R,Reinhart K,Brunkhorst FM,Dobb G,Levy M,Martin G,Martin C,Ramsey G,Silva E,Vallet B,Vincent JL,Janes JM,Sarwat S,Williams MD,PROGRESS Advisory Board.

    更新日期:2009-06-01 00:00:00

  • Anaerobic microbiology in the NASA space program.

    abstract::After briefly reviewing the earlier methods used to monitor the microbial load of returned lunar material, the author reports the more accurate research on the ability of terrestrial organisms to grow under simulated Martian environments. The possible importance of anaerobic microbiology can readily be seen because of...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01639903

    authors: Brewer JH

    更新日期:1980-01-01 00:00:00

  • Procalcitonin in patients with and without immunosuppression and sepsis.

    abstract::High serum levels of procalcitonin (PCT) are observed in patients with sepsis or severe infection. In a prospective study of 122 hospitalised adult medical patients with sepsis, serum PCT was determined on admission and for 9 days thereafter. Patients with no alteration in their immune system showed high PCT values up...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01713044

    authors: al-Nawas B,Shah PM

    更新日期:1996-11-01 00:00:00

  • Management of superficial and deep-seated Staphylococcus aureus skin and soft tissue infections in sub-Saharan Africa: a post hoc analysis of the StaphNet cohort.

    abstract:PURPOSE:The incidence of Staphylococcus aureus skin and soft tissue infection (SSTI) is high in sub-Saharan Africa. This is fueled by a high prevalence of Panton-Valentine leukocidin (PVL), which can be associated with necrotizing disease. The aim was to describe the clinical presentation and the treatment of SSTI in t...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-018-1140-6

    authors: Alabi A,Kazimoto T,Lebughe M,Vubil D,Phaku P,Mandomando I,Kern WV,Abdulla S,Mellmann A,Peitzmann L,Bischoff M,Peters G,Herrmann M,Grobusch MP,Schaumburg F,Rieg S

    更新日期:2018-06-01 00:00:00

  • Interaction between levothyroxine and indinavir in a patient with HIV infection.

    abstract::Drug interactions are an important and emerging problem in the treatment of HIV-infected patients. Protease inhibitors, like nonnucleoside reverse transcriptase inhibitors, are metabolized by the cytochrome P-450 enzyme system and each of these antiretroviral agents may interact with other drugs metabolized by this sy...

    journal_title:Infection

    pub_type: 信件

    doi:10.1007/s15010-002-2092-3

    authors: Lanzafame M,Trevenzoli M,Faggian F,Marcati P,Gatti F,Carolo G,Concia E

    更新日期:2002-01-01 00:00:00

  • Factors indicative of outcome in a comparative trial of acyclovir and vidarabine for biopsy-proven herpes simplex encephalitis.

    abstract::A total of 208 patients underwent brain biopsy for presumptive herpes simplex encephalitis and were randomized to receive either vidarabine, vira-A, at 15 mg/kg/day, or acyclovir, at 30 mg/kg/day for ten days. 69 patients (33%) had biopsy-proven disease; 37 received vira-A and 32 acyclovir. With the exception of age, ...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01650104

    authors: Whitley RJ,Alford CA,Hirsch MS,Schooley RT,Luby JP,Aoki FY,Hanley D,Nahmias AJ,Soong SJ

    更新日期:1987-01-01 00:00:00

  • Invasive listeriosis in a patient with several episodes of antibiotic associated colitis presumably due to Clostridium difficile.

    abstract::A 62-year-old man developed a blood stream infection and meningitis due to Listeria monocytogenes, 20 days after an episode of pseudo-membranous colitis. The patient, hospitalized for the first time for transurethral prostatectomy, was readmitted 20 days later with watery diarrhea. Pseudo-membranous colitis was diagno...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-017-1013-4

    authors: Carannante N,Pagliano P,Rossi M,Attanasio V,Rescigno C,Corte L,Tascini C,Cardinali G

    更新日期:2017-06-01 00:00:00

  • Implementation of multidrug-resistant tuberculosis (MDR-TB) treatment in Gabon: lessons learnt from the field.

    abstract:PURPOSE:Since May 2016, WHO recommended a 9-12 month short-treatment regimen for multidrug-resistant tuberculosis (MDR-TB) treatment known as the 'Bangladesh Regimen'. However, limited data exist on the appropriateness thereof, and its implementation in low- and middle-income countries (LMIC). We report here on the pil...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-019-01314-5

    authors: Ateba-Ngoa U,Edoa JR,Adegbite BR,Rossatanga EG,Madiou D,Mfoumbi A,Mevyann C,Achimi Agbo P,Mahoumbou J,Gould S,Lell B,Adegnika AA,Köhler C,Kremsner PG,Massinga-Loembe M,Alabi A,Grobusch MP

    更新日期:2019-10-01 00:00:00

  • Occurrence of methicillin-resistant Staphylococcus aureus infections in German intensive care units.

    abstract:BACKGROUND:This study aims to describe the occurrence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infections and the relation between endemic and epidemic nosocomial MRSA infections in intensive care units (ICUs) in Germany. METHODS:The ICU component within the German national nosocomial infection...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-002-2043-z

    authors: Gastmeier P,Sohr D,Geffers C,Nassauer A,Dettenkofer M,Rüden H

    更新日期:2002-08-01 00:00:00