Abstract：
:Using immunohistological techniques, class 1 products of the major histocompatibility complex (MHC) have been demonstrated on various forms of human extra-villous trophoblast in placental tissues taken from first, second and third trimester pregnancies. This contrasts with the absence of class 1 MHC antigens on all forms of villous trophoblast. The extra-villous trophoblast which reacted with antibodies to monomorphic class 1 MHC antigens consistently failed to bind HLA-A or HLA-B antibodies specific for the foetal phenotype. This suggests, but does not prove, that the MHC antigen expression of trophoblast may be restricted to HLA-C or some other undefined class 1 antigen.
journal_name
Immunologyjournal_title
Immunologyauthors
Redman CW,McMichael AJ,Stirrat GM,Sunderland CA,Ting Asubject
Has Abstractpub_date
1984-07-01 00:00:00pages
457-68issue
3eissn
0019-2805issn
1365-2567journal_volume
52pub_type
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