The quantitative distribution of percutaneously applied caffeine in the human skin.

abstract：:T Cells from 14 patients in the active stage of bullous pemphigoid and 10 patients in the inactive stage of the disease were studied with Leu-1, Leu-2, and Leu-3 monoclonal antibodies. The proportions of total T cells and T cells expressing either helper or suppressor phenotype in the peripheral blood of patients were...

journal_title：Archives of dermatological research

authors： Ahmed AR

更新日期：1985-01-01 00:00:00

abstract：:As the main nitrogen source in Malassezia furfur, tryptophan induces the formation of fluorochromes and pigments, which make the yeast less sensitive to UV light. To detect a chemical UV filter, M. furfur (CBS 1878) was incubated at 30 degrees C for 14 days on a pigment-inducing medium and agar extracts were purified ...

journal_title：Archives of dermatological research

authors： Mayser P,Schäfer U,Krämer HJ,Irlinger B,Steglich W

更新日期：2002-05-01 00:00:00

abstract：:Solar radiation in the UVB range is absorbed primarily by the epidermal DNA where characteristic photodamage results in altered immune responses and mutagenic lesions. UVB exposure of the skin results in a profound upregulation of the anti-inflammatory cytokine, IL-10 and suppression of contact hypersensitivity (CHS)....

journal_title：Archives of dermatological research

authors： Ma LJ,Guzmán EA,DeGuzman A,Walter B,Muller HK,Walker AM,Owen LB

更新日期：2006-03-01 00:00:00

abstract：:Fingernail growth was studied in 28 patients who were receiving systemic treatment with the aromatic retinoid, Ro 10-9359 known as Tigason (etretinate; AR). A group of 15 patients with psoriasis was compared with a group of 13 patients with other dermatoses which are known to have a good response to AR therapy. In the...

journal_title：Archives of dermatological research

authors： Galosi A,Plewig G,Braun-Falco O

更新日期：1985-01-01 00:00:00

abstract：:All-trans retinoic acid (ATRA) is known to have beneficial effects on skin. It has been used extensively for the treatment of photodamaged skin. To assess the effects of all-trans retinoic acid on the dermis, specifically its effect on hyaluronate (hyaluronic acid, HA) synthesis and inhibition, tissue-engineered human...

journal_title：Archives of dermatological research

authors： Deshpande M,Papp S,Schaffer L,Pouyani T

更新日期：2014-09-01 00:00:00

abstract：:Wound healing could be categorized as a chronic disorder which needs a prompt and effective medication. Nowadays, vascular problems and wound-healing progression studies relay on the role of metformin; however, the exact mechanisms for its beneficial effects are still not completely understood. The aim of the present ...

journal_title：Archives of dermatological research

authors： Tawfeek HM,Abou-Taleb DAE,Badary DM,Ibrahim M,Abdellatif AAH

更新日期：2020-03-01 00:00:00

abstract：:Epidermolytic hyperkeratosis (EH) is a genetic disorder of keratins associated with epidermal differentiation. Affected individuals carry gene mutations for conserved sequences of keratins K1 or K10. The structural alterations of tonofilaments in EH seem to be a direct consequence of the keratin gene mutations. EH epi...

journal_title：Archives of dermatological research

authors： Ishida-Yamamoto A,Iizuka H,Manabe M,O'Guin WM,Hohl D,Kartasova T,Kuroki T,Roop DR,Eady RA

更新日期：1995-01-01 00:00:00

abstract：:The stratum corneum, which is the outermost layer of the skin, functions as an important barrier to maintain biological homeostasis. The multilamellar structures formed by intercellular lipids present in the stratum corneum are considered to play an important role in barrier function. Most intercellular lipids are unb...

journal_title：Archives of dermatological research

authors： Meguro S,Arai Y,Masukawa Y,Uie K,Tokimitsu I

更新日期：2000-09-01 00:00:00

abstract：:Bradykinin has long been postulated to have a major role in physiologic human pain production. We have developed a method to systematically quantify the algogenic response to bradykinin in human skin by the direct application of bradykinin to suction blister bases. After determination of the pain threshold to bradykin...

journal_title：Archives of dermatological research

authors： Schneider BK,Morelli JG,Vavrek RJ,Stewart JM,Weston WL

更新日期：1992-01-01 00:00:00

abstract：:The cellular origin of Merkel cell carcinoma (MCC) is controversial. We previously hypothesized that MCC originates from hair follicle stem cells or Merkel cell (MC) progenitors residing within the hair follicle bulge. Examination of three cases of combined MCC led to the unexpected discovery that numerous keratin 20 ...

journal_title：Archives of dermatological research

authors： Narisawa Y,Inoue T,Nagase K

更新日期：2019-01-01 00:00:00

abstract：:Heparin-binding EGF-like growth factor (HB-EGF) and amphiregulin (AREG) are the members of EGF family that bind to common EGF receptor (EGFR) in the epidermis. However, the role of these two growth factors in epidermal hyperplasia of psoriasis has not been established. On the other hand, CD4+ T cells are responsible f...

journal_title：Archives of dermatological research

authors： Yoshida A,Kanno H,Watabe D,Akasaka T,Sawai T

更新日期：2008-01-01 00:00:00

abstract：:Melanoma incidence in Australia remains the highest in the world; hence understanding its causation is paramount for future therapeutic developments. Multiple primary melanomas are also common occurrences among the Australian population with identified risk factors such as personal and family history of melanoma, fair...

journal_title：Archives of dermatological research

authors： Sinnya S,Jagirdar K,De'Ambrosis B,McMeniman E,Sturm RA,Soyer HP

更新日期：2015-10-01 00:00:00

abstract：:Epstein-Barr virus (EBV) can infect epithelial cells as well as B lymphocytes. Infection of the male and female genital tracts has recently been demonstrated, and it has been suggested that the virus may be sexually transmissible. In our study we investigated whether EBV can be found in the anal region of sexually act...

journal_title：Archives of dermatological research

authors： Näher H,Lenhard B,Wilms J,Nickel P

更新日期：1995-01-01 00:00:00

abstract：:This study probes the extent of coupling between the reversal of epidermal hyperproliferation induced by essential fatty acid (EFA) deficiency in guinea pigs, the hydrolysis of epidermal phosphatidylinositol 4,5-bisphosphate (PtdIns4,5P2), and the rapid formation of inositol triphosphate (InsP3). Our data revealed tha...

journal_title：Archives of dermatological research

authors： Tang W,Ziboh VA

更新日期：1988-01-01 00:00:00

abstract：:Genetic abnormalities for different subtypes of epidermolysis bullosa (EB) have been described. In dominant simplex type EB, mutations of the K5 or K14 gene lead to disruption of basal cells and the formation of bullae. The recessive simplex types include EB with muscular dystrophy due to abnormal plectin, EB without ...

journal_title：Archives of dermatological research

authors： Mitsuhashi Y,Hashimoto I

更新日期：2003-04-01 00:00:00

abstract：:Psoriasis, a chronic inflammatory skin disease, is associated with oxidative stress of serum lipoproteins. In psoriatic children we evaluated the activity and levels of myeloperoxidase, the activity of paraoxonase-1 (PON1) and biochemical markers of lipid peroxidation, to investigate wether an unbalance between oxidan...

journal_title：Archives of dermatological research

authors： Bacchetti T,Simonetti O,Ricotti F,Offidani A,Ferretti G

更新日期：2020-01-01 00:00:00

abstract：:Dendritic cell (DC) maturation is essential for the initiation of T-dependent immune responses. Nuclear factor kappa B (NF-kappaB) transcription factors are ubiquitously expressed signalling molecules, known to regulate the transcription of a large number of genes involved in immune responses, including cytokines and ...

journal_title：Archives of dermatological research

authors： Cruz MT,Duarte CB,Gonçalo M,Figueiredo A,Carvalho AP,Lopes MC

更新日期：2002-12-01 00:00:00

abstract：:In this study, a new procedure for the cultivation of dermal vascular endothelial cells from guinea pig ear lobe was established, and specific binding of [3H]mepyramine to the cultured cell membranes was demonstrated. The vascular endothelial cells were successfully isolated from the dermis of guinea pig ear lobes by ...

journal_title：Archives of dermatological research

authors： Noso N,Hide M,Nakamura K,Yamamoto S

更新日期：1990-01-01 00:00:00

abstract：:Comparative measurements of collagen synthesis as a portion of total protein synthesis were performed with fragments of peripheral neurofibromas, of skin adjacent to the tumors, and of unaffected skin from patients with neurofibromatosis (NF). No significant difference was found among these various samples. Collagen s...

journal_title：Archives of dermatological research

authors： Mühleck O,Krone W,Mao R,Weber L

更新日期：1986-01-01 00:00:00

abstract：:Hand warts were studied in 160 butchers. Clinical and histological studies were performed in 190 warts and virological studies in 165 warts from 104 butchers. Since we found almost perfect correlation between the histological pattern and the type of infecting virus, it was possible to evaluate the virus types in a fur...

journal_title：Archives of dermatological research

authors： Jablońska S,Obalek S,Favre M,Golebiowska A,Croissant O,Orth G

更新日期：1987-01-01 00:00:00

abstract：:To find novel depigmenting agents, a new synthetic compound, N-adamantyl-3,4-dihydroxybenzamide (NADB) was produced and the effects on melanogenesis were investigated. Our results showed that NADB reduced melanin synthesis in a dose-dependent manner in melan-a cells. Tyrosinase activity was also reduced by NADB treatm...

journal_title：Archives of dermatological research

authors： Rho HS,Ahn SM,Hwang JS

更新日期：2011-04-01 00:00:00

abstract：:Bromodeoxyuridine (BrdU) has commonly been used for detecting of label-retaining cells (LRCs). To determine if there are LRCs and the distributions of LRCs in eccrine sweat glands, 20 newborn SD rats within 24 h after birth were injected intraperitoneally with 50 mg/kg/time BrdU four consecutive times at 2-h intervals...

journal_title：Archives of dermatological research

authors： Chen L,Zhang M,Li H,Tang S,Fu X

更新日期：2014-03-01 00:00:00

abstract：:The beta-adrenergic receptors, previously shown to be present on the membranes of cultured human epidermal keratinocytes, were found to be functionally coupled to membrane-bound adenylate cyclase. Using membrane preparations, the enzyme could be activated by guanosine triphosphate (GTP), the stable GTP analog GPP(HN)p...

journal_title：Archives of dermatological research

authors： Cavey MT,Cavey D,Shroot B,Reichert U,Gazith J

更新日期：1986-01-01 00:00:00

abstract：:The hair cycling pattern differs between humans and mice: for the former it is mosaic, while the latter show a wave pattern. We focused on the presence or absence of synchronization of the hair cycle based on the distribution of Merkel cells. The three-dimensional distribution and number of Merkel cells in the skin at...

journal_title：Archives of dermatological research

authors： Tanaka T,Narisawa Y

更新日期：2000-04-01 00:00:00

abstract：:The treatment of epidermolysis bullosa acquisita (EBA) is difficult and often disappointing. We report on the successful treatment of two EBA patients with colchicine. The drug was administered orally at an initial dose of 2 mg/day. After 2 weeks of therapy a dramatic improvement was observed. Most of the cutaneous an...

journal_title：Archives of dermatological research

authors： Megahed M,Scharffetter-Kochanek K

更新日期：1994-01-01 00:00:00

abstract：:As congenital nevocytic nevi have an increased risk of malignant degeneration, nevus-cell involvement in blood vessels and lymphatics is of particular interest. The present histological and ultrastructural studies revealed nevus-cell nests in the walls of venules in 1 out of 11 patients with medium-sized nevi, and in ...

journal_title：Archives of dermatological research

authors： Schneider BV,Maie O

更新日期：1985-01-01 00:00:00

abstract：:Topical vitamin D3 has relatively recently been introduced for the treatment of psoriasis. Synthetic vitamin D3 analogues with a high potential for inducing differentiation of cells, but with a low hypercalcemic effect have recently been developed. One such synthetic analogue of 1,25-dihydroxyvitamin D3 (calcitriol), ...

journal_title：Archives of dermatological research

authors： Komine M,Watabe Y,Shimaoka S,Sato F,Kake K,Nishina H,Ohtsuki M,Nakagawa H,Tamaki K

更新日期：1999-09-01 00:00:00

abstract：:Reactive oxygen species (ROS) play important roles in the process of ultraviolet-induced skin damage or photoaging. Although many enzymatic and chemical methods have been developed for evaluating ROS, evaluation methods for ROS generation in living systems are quite limited. Here we propose a unique system to visualiz...

journal_title：Archives of dermatological research

authors： Hakozaki T,Date A,Yoshii T,Toyokuni S,Yasui H,Sakurai H

更新日期：2008-04-01 00:00:00

abstract：:Eighteen patients with atopic dermatitis were randomly chosen for a clinical trial to compare the action of the H2 receptor antagonist cimetidine in combination with the H1 receptor antagonist chorpheniramine against the chlorpheniramine alone and against placebo. Each treatment period lasted for 4 weeks. Intensity of...

journal_title：Archives of dermatological research

authors： Frosch PJ,Schwanitz HJ,Macher E

更新日期：1984-01-01 00:00:00

abstract：:Medical innovation is crucial to advancing our field, and physicians have the potential to play a leading role due to their daily patient care experiences. The objective of this study was to evaluate the interest in, and barriers to participating in innovation. Two surveys were conducted; the first cross-sectional sur...

journal_title：Archives of dermatological research

authors： Lee KC,Lee I,Okhovat JP,Ko J,Powers JG,Ellis DL,Cheeley J,Garibyan L

更新日期：2020-08-09 00:00:00