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Host specificity of DNA produced by Escherichia coli. XI. In vitro modification of phage fd replicative form.

Abstract：

:An enzymatic activity, having the properties expected of a B-specific host-controlled modification enzyme, has been purified from an extract of Escherichia coli strain B. This activity renders the unmodified replicative form of phage fd resistant to B-specific restriction and is only present in strains carrying intact genes for type B modification. In phosphate buffer, the enzyme acts optimally at pH 6 and is dependent upon a single cofactor, S-adenosylmethionine.

journal_name

Proc Natl Acad Sci U S A

journal_title

Proceedings of the National Academy of Sciences of the United States of America

authors

Kühnlein U,Linn S,Arber W

doi

10.1073/pnas.63.2.556

subject

Has Abstract

pub_date

1969-06-01 00:00:00

pages

556-62

issue

2

eissn

0027-8424

issn

1091-6490

journal_volume

63

pub_type

杂志文章

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