Subapical wall synthesis and wall thickening induced by cycloheximide in hyphae of Aspergillus nidulans.

Abstract:

:Hyphae of Aspergillus nidulans continued to synthesize all the major polysaccharide components of the cell wall when cycloheximide was added to cultures. In the presence of cycloheximide, hyphae did not elongate, but electron microscopy showed that the walls became thicker around the cell. The conclusion that cycloheximide changed wall synthesis from extension at the apex to subapical thickening was supported by grain distributions on radioautograms of mutant hyphae labeled with galactose. These findings are discussed in relation to the control of hyphal wall synthesis and are compared with the effects of protein synthesis inhibitors on wall formation in gram-positive bacteria.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Sternlicht E,Katz D,Rosenberger RF

doi

10.1128/JB.114.2.819-823.1973

subject

Has Abstract

pub_date

1973-05-01 00:00:00

pages

819-23

issue

2

eissn

0021-9193

issn

1098-5530

journal_volume

114

pub_type

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