Hepatic infarction and diabetic ketoacidosis.

abstract：BACKGROUND & AIMS:Lamivudine inhibits hepatitis B virus replication. This study investigated 6 months of lamivudine treatment at three doses. METHODS:Fifty-one patients (43% white, 49% Asian) with chronic hepatitis B were randomly assigned to receive 25, 100, or 300 mg of lamivudine orally once daily for 24 weeks with...

journal_title：Gastroenterology

authors： Nevens F,Main J,Honkoop P,Tyrrell DL,Barber J,Sullivan MT,Fevery J,De Man RA,Thomas HC

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND & AIMS:Tumors that develop in patients with Crohn's disease tend be multifocal, so field cancerization (the replacement of normal cells with nondysplastic but tumorigenic clones) might contribute to intestinal carcinogenesis. We investigated patterns of tumor development from pretumor intestinal cell clones....

journal_title：Gastroenterology

authors： Galandiuk S,Rodriguez-Justo M,Jeffery R,Nicholson AM,Cheng Y,Oukrif D,Elia G,Leedham SJ,McDonald SA,Wright NA,Graham TA

更新日期：2012-04-01 00:00:00

abstract：:Heterogeneity of colonic mucin glycoprotein was examined in rectal mucosal biopsy specimens from a variety of primate species (Saguinus oedipus, n = 18; Macaca mulatta, n = 2; Macaca fascicularis, n = 2; Aotus trivirgatus, n = 2; Saimiri sciureus, n = 2; and Callithrix jacchus, n = 2). After initial separation of radi...

journal_title：Gastroenterology

authors： Podolsky DK,Madara JL,King N,Sehgal P,Moore R,Winter HS

更新日期：1985-01-01 00:00:00

abstract：:To characterize gastric mucosal perfusion in cirrhotic patients with portal hypertensive gastropathy, 34 cirrhotics with this lesion and 24 noncirrhotics were studied by reflectance spectrophotometry and laser-Doppler flowmetry during endoscopy. A significant correlation was observed between the hemoglobin content of ...

journal_title：Gastroenterology

authors： Panés J,Bordas JM,Piqué JM,Bosch J,García-Pagán JC,Feu F,Casadevall M,Terés J,Rodés J

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND & AIMS:The role of the gallbladder in gallstone pathogenesis is still unclear. We examined the effects of gallbladder mucosal lipid absorption on lipid composition and cholesterol crystallization in bile. METHODS:The in vitro-isolated, intra-arterially perfused gallbladder model was used (1) to compare the ...

journal_title：Gastroenterology

authors： Corradini SG,Elisei W,Giovannelli L,Ripani C,Della Guardia P,Corsi A,Cantafora A,Capocaccia L,Ziparo V,Stipa V,Chirletti P,Caronna R,Lomanto D,Attili AF

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND AIMS:CD4+CD25+Foxp3+ T-regulatory (Treg) cells control immune responses and maintain immune homeostasis. However, under inflammatory conditions, Treg cells produce cytokines that promote inflammation. We investigated production of tumor necrosis factor (TNF) by Treg cells in patients with acute hepatitis...

journal_title：Gastroenterology

authors： Choi YS,Jung MK,Lee J,Choi SJ,Choi SH,Lee HW,Lee JJ,Kim HJ,Ahn SH,Lee DH,Kim W,Park SH,Huh JR,Kim HP,Park JY,Shin EC

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND & AIMS:Studies on the early steps in the life cycle of hepatitis B virus have been hampered by the lack of readily available target cells. In this study, we mapped a defined virus attachment site to primary hepatocytes that is essential for infection. METHODS:We used purified virus particles from human carr...

journal_title：Gastroenterology

authors： Glebe D,Urban S,Knoop EV,Cag N,Krass P,Grün S,Bulavaite A,Sasnauskas K,Gerlich WH

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND & AIMS:Diarrheal disease is a major cause of morbidity and mortality in infants and children worldwide. Evidence has indicated immature human enterocytes and their interaction with bacteria and enterotoxins may account for the noted increased susceptibility of neonates to diarrhea. Our aim was to characteriz...

journal_title：Gastroenterology

authors： Lu L,Bao Y,Khan A,Goldstein AM,Newburg DS,Quaroni A,Brown D,Walker WA

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND & AIMS:Crohn's disease (CD) usually recurs after intestinal resection; postoperative endoscopic monitoring and tailored treatment can reduce the chance of recurrence. We investigated whether monitoring levels of fecal calprotectin (FC) can substitute for endoscopic analysis of the mucosa. METHODS:We analyze...

journal_title：Gastroenterology

authors： Wright EK,Kamm MA,De Cruz P,Hamilton AL,Ritchie KJ,Krejany EO,Leach S,Gorelik A,Liew D,Prideaux L,Lawrance IC,Andrews JM,Bampton PA,Jakobovits SL,Florin TH,Gibson PR,Debinski H,Macrae FA,Samuel D,Kronborg I,Radfor

更新日期：2015-05-01 00:00:00

abstract：:A patient with gastric outlet syndrome (Bouveret's syndrome) caused by a large gallstone impacted in the duodenal bulb was successfully treated by extracorporeal shock-wave lithotripsy. Thus, open abdominal surgery could be avoided. For disintegration of the stone, three consecutive lithotripsy procedures were necessa...

journal_title：Gastroenterology

authors： Holl J,Sackmann M,Hoffmann R,Schüssler P,Sauerbruch T,Jüngst D,Paumgartner G

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND & AIMS:Although restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) substantially reduces the risk of colorectal cancer in patients with inflammatory bowel disease (IBD), subsequent pouch neoplasia can develop. There are few data on the incidence of and risk factors for neoplasia, so there i...

journal_title：Gastroenterology

authors： Derikx LA,Kievit W,Drenth JP,de Jong DJ,Ponsioen CY,Oldenburg B,van der Meulen-de Jong AE,Dijkstra G,Grubben MJ,van Laarhoven CJ,Nagtegaal ID,Hoentjen F,Dutch Initiative on Crohn and Colitis.

更新日期：2014-01-01 00:00:00

abstract：:The published world literature on the efficacy of cimetidine, a histamine H2-receptor antagonist, in the treatment of duodenal ulcer is reviewed. In eight prospective randomized double blind placebo-controlled studies, cimetidine was administered to 348 duodenal ulcer patients with an incidence of endoscopically verif...

journal_title：Gastroenterology

authors： Winship DH

更新日期：1978-02-01 00:00:00

abstract：:Canine ileal segments were luminally perfused with known amounts of polyethylene glycol (PEG), and samples obtained were freed of protein by a cold acetone (CA) method and assayed for PEG by trichloroacetic acid in the presence of calcium cations. This procedure was compared to the Barium salt (BaS) protein precipitat...

journal_title：Gastroenterology

authors： Buxton TB,Crockett JK,Moore WL 3rd,Moore WL Jr,Rissing JP

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND & AIMS:Little is known about the prevalence of nonalcoholic fatty liver disease (NAFLD) among severely obese adolescents or factors that determine its development. We investigated the prevalence of NAFLD in a multicenter cohort of adolescents undergoing bariatric surgery and the factors associated with it. ...

journal_title：Gastroenterology

authors： Xanthakos SA,Jenkins TM,Kleiner DE,Boyce TW,Mourya R,Karns R,Brandt ML,Harmon CM,Helmrath MA,Michalsky MP,Courcoulas AP,Zeller MH,Inge TH,Teen-LABS Consortium.

更新日期：2015-09-01 00:00:00

abstract：:Neuron specific enolase, the most acidic isoenzyme of the glycolytic enzyme enolase, was first believed to be present exclusively in central neurons. More recently, it has been found in peripheral autonomic nerves and in a number of endocrine cells. An immunocytochemical study was carried out concerning the distributi...

journal_title：Gastroenterology

authors： Bishop AE,Polak JM,Facer P,Ferri GL,Marangos PJ,Pearse AG

更新日期：1982-10-01 00:00:00

abstract：:We have prospectively evaluated 41 patients who ingested acid for location, extent, severity, and outcome of the injury to the upper gastrointestinal tract. The injury was assessed within 36 h of acid intake by endoscopy or surgery, or at autopsy. Symptoms and signs were unreliable in predicting the extent and severit...

journal_title：Gastroenterology

authors： Zargar SA,Kochhar R,Nagi B,Mehta S,Mehta SK

更新日期：1989-09-01 00:00:00

abstract：:Thyrotropin-releasing hormone transiently increased resting tension and spontaneous contraction amplitude more potently in longitudinal muscle than in circular muscle. The frequency of the contraction did not change. Excitation was enhanced by eserine, and blocked by atropine and tetrodotoxin; this excitation was, the...

journal_title：Gastroenterology

authors： Oouchi M,Ichikawa S

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Endogenous nitric oxide has been implicated in the control of mesenteric circulation, but its role in the control of pancreatic blood flow and exocrine pancreatic secretion has not been studied. METHODS:Secretory studies were performed on conscious dogs with chronic pancreatic fistulas, and changes in pancr...

journal_title：Gastroenterology

authors： Konturek SJ,Bilski J,Konturek PK,Cieszkowski M,Pawlik W

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND & AIMS:MicroRNAs (miRNAs) can promote or inhibit tumor growth and are therefore being developed as targets for cancer therapies. They are diverse not only in the messenger RNAs (mRNA) they target, but in their production; the same hairpin RNA structure can generate mature products from each strand, termed 5p...

journal_title：Gastroenterology

authors： Almeida MI,Nicoloso MS,Zeng L,Ivan C,Spizzo R,Gafà R,Xiao L,Zhang X,Vannini I,Fanini F,Fabbri M,Lanza G,Reis RM,Zweidler-McKay PA,Calin GA

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND & AIMS:Colonic crypt elongation occurs during both chronic colitis and in the recovery phase of acute colitis. The impact of these alterations on epithelial cell functions is not fully defined. METHODS:DNA microarray analysis of freshly isolated colonic epithelial cells (CECs) from acute and chronic colitis...

journal_title：Gastroenterology

authors： Mizoguchi E,Xavier RJ,Reinecker HC,Uchino H,Bhan AK,Podolsky DK,Mizoguchi A

更新日期：2003-07-01 00:00:00

abstract：:A patient with post-traumatic seizure disorder developed lymphadenopathy, exfoliative dermatitis, and hepatic failure while on diphenylhydantoin therapy and died in hepatic coma. Autopsy disclosed massive hepatic necrosis. The clinical and pathological pictures are similar to the six previously reported cases of diphe...

journal_title：Gastroenterology

authors： Lee TJ,Carney CN,Lapis JL,Higgins T,Fallon HJ

更新日期：1976-03-01 00:00:00

abstract：:Gastrointestinal symptoms occur in a large number of patients with food allergies. Immediate hypersensitivity mechanisms may give rise to the nausea, vomiting, abdominal pain, and diarrhea experienced by these patients. However, there are limited human data about the pathophysiological basis for these symptoms. Most o...

journal_title：Gastroenterology

authors： Crowe SE,Perdue MH

更新日期：1992-09-01 00:00:00

abstract：:The noninvasive assessment of intestinal permeability in humans has a 20-year history. Because the tests are increasingly used in clinical practice and research and because there is much controversy, we reviewed the literature and outlined the potential and possible shortcomings of these procedures. Data was obtained ...

journal_title：Gastroenterology

authors： Bjarnason I,MacPherson A,Hollander D

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND & AIMS:Knowledge of the placebo outcomes and understanding specific study features that influence these outcomes is important for designing future clinical trials evaluating therapy of ulcerative colitis (UC). The aims of this study were to estimate the placebo rates of remission and response in placebo-cont...

journal_title：Gastroenterology

authors： Su C,Lewis JD,Goldberg B,Brensinger C,Lichtenstein GR

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND & AIMS:An increased duodenal expression of the iron transporters, divalent-metal-transporter-1, and ferroportin is observed in patients with iron deficiency or hereditary hemochromatosis. Two oxidoreductases, termed duodenal cytochrome b and hephaestin, are proposed to co-operate with divalent-metal-transpor...

journal_title：Gastroenterology

authors： Zoller H,Theurl I,Koch RO,McKie AT,Vogel W,Weiss G

更新日期：2003-09-01 00:00:00

abstract：:A monoclonal antibody to bromodeoxyuridine was used in tissue specimens previously incubated with bromodeoxyuridine to show S-phase cells by immunohistochemical technique. Biopsy specimens of normal mucosa (n = 10), hyperplastic polyps (n = 10), adenomas with low-grade dysplasia (n = 20), adenomas with high-grade dysp...

journal_title：Gastroenterology

authors： Risio M,Coverlizza S,Ferrari A,Candelaresi GL,Rossini FP

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND & AIMS:The basic mechanisms of food allergies are still unknown. The aims of this study were to investigate whether endothelins (ETs) in the intestinal mucosa are involved in the pathogenesis of intestinal anaphylaxis. METHODS:Sprague-Dawley rats were sensitized to chicken egg albumin (EA) by intraperitonea...

journal_title：Gastroenterology

authors： Shigematsu T,Miura S,Hirokawa M,Hokari R,Higuchi H,Tsuzuki Y,Kimura H,Nakatsumi RC,Serizawa H,Saito H,Ishii H

更新日期：1998-08-01 00:00:00

abstract：:Low residue, chemically defined diets containing all essential nutrients in a readily assimilated form, require minimal digestion and are almost entirely absorbed in the upper gastrointestinal tract. Within the past decade, these diets have been reported to provide nutritional support in a variety of clinical situatio...

journal_title：Gastroenterology

authors： Young EA,Heuler N,Russell P,Weser E

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND & AIMS:Although patients with inflammatory bowel disease (IBD) have reduced bone mass, there is controversy whether there is an increased risk of fracture. This study examines the risk of fracture and its predictors in patients with IBD. METHODS:In a primary care- based nested case-control study, 231,778 fr...

journal_title：Gastroenterology

authors： van Staa TP,Cooper C,Brusse LS,Leufkens H,Javaid MK,Arden NK

更新日期：2003-12-01 00:00:00

abstract：:Using an in vivo canine chambered stomach preparation, the clearance of [14C]aminopyrine across mucosa when intravenously infused and the back-diffusion of this substance from gastric lumen to mucosa when topically applied to gastric epithelium were evaluated in aspirin-damaged gastric epithelium. In mucosa damaged by...

journal_title：Gastroenterology

authors： Miller TA,Henagan JM,Loy TM

更新日期：1983-09-01 00:00:00