Abstract:
:The ultrastructure of the optic and trigeminal nerves of the rat, cryofixed by use of a liquid nitrogen-propane jet, was examined, paying special attention to the myelin sheath and the cytoskeleton of the axoplasm. The cytoskeleton of the axoplasm is formed by a meshwork of neurofilaments and microtubules connected both to each other and also to the cell organelles and axolemma. These cross-linkers are fixed to the longitudinal neurofilaments in a helical arrangement, which could be a morphological substrate for the diverse axonal transport phenomena. The myelin sheath is formed by concentrically apposed membrane pairs, which are not fused together. The corresponding major and intraperiod lines seen using classical electron microscopy are in fact fissures that are obscured by the pattern of the selective deposition of osmium at certain sites and cannot be interpreted as specific structures. The cryofixed myelin membranes have the appearance of predominantly globular subunits arranged in an asymmetrical bilayer. The globular particles are of diverse diameter and occupy varying positions within the membrane. The tight junctions or zonulae occludentes of the myelin are formed by arrays of isolated particles, and consequently the fibril formation seems to be a result of the chemical fixation.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Meller Kdoi
10.1007/BF00214541subject
Has Abstractpub_date
1985-01-01 00:00:00pages
289-300issue
2eissn
0302-766Xissn
1432-0878journal_volume
242pub_type
杂志文章abstract::Beta-defensin 103 (DEFB103) shares little homology with 8 other members of the bovine beta-defensin family and in other species DEFB103 protein has diverse functions, including antimicrobial activity, a chemoattractant for dendritic cells, enhancing epithelial wound repair and regulating hair colour. Expression of the...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-015-2258-9
更新日期:2016-02-01 00:00:00
abstract::The present immunocytochemical study concerns the distribution of four neuropeptides, FMRF-amide, vasotocin, leu-enkephalin and neurotensin, and of the bioamine serotonin in the plerocercoid larva of Diphyllobothrium dendriticum. Anti-FMRF-amide and vasotocin-reactivity occurs in perikarya and nerve fibres in the CNS ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222332
更新日期:1985-01-01 00:00:00
abstract::The prolactin-producing cells are the first hormone-producing cells of the pars distalis to be differentiated within Ambystoma gracile. They first appear when the larvae attain a length of approximately 3.0 cm snout to vent length (SVL). Thyrotropes are observed as the next chromophilic cells to appear, and they occur...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00223121
更新日期:1978-05-18 00:00:00
abstract::Previous studies have revealed a remarkable capacity of intracerebral grafts of embryonic brain tissue to establish extensive axonal connections with denervated areas in the brains of adult rats. In the present study we have explored the possibilities of using grafts in the spinal cord to substitute for the loss of no...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216024
更新日期:1983-01-01 00:00:00
abstract::Mast cells (MCs) and airway nerves play an important role in allergic asthma. However, little is known about the MCs and their interaction with airway nerves during allergic airway inflammation. This study aims to investigate the distribution and proliferation of MC populations in different lung compartments, along wi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-017-2597-9
更新日期:2017-08-01 00:00:00
abstract::Subsurface cisterns (SSC's) and less frequent lamellar bodies (LB's) were identified in the granule cells of the guinea-pig fascia dentata. Both structures, composed of flattened or collapsed agranular cisterns, are continuous with the regular rough endoplasmic reticulum and occasionally connected with each other form...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF01258502
更新日期:1982-01-01 00:00:00
abstract::The distribution of neuronal elements immunoreactive for gamma-aminobutyric acid (GABA) and glycine in the cochlear nucleus of the mustached bat Pteronotus parnellii has been studied by means of the postembedding technique on serial semithin sections. Our goal has been to identify similarities and differences in the o...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050773
更新日期:1997-02-01 00:00:00
abstract::More than twenty different enzyme activities of fractions containing dictyosome-like structures (DLS) as a dominant cell component were monitored. Plasma membrane vesicles were a major contaminant of the DLS fractions, which, presumably as a consequence, were enriched somewhat in plasma membrane markers. The lysosomal...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217555
更新日期:1985-01-01 00:00:00
abstract::Interstitial cells of Cajal (ICCs) are believed to be a major element in generating the spontaneous rhythm of the gastrointestinal tract. A prominent problem in the study of these cells has been the difficulty in observing them in intact tissues. We used the lipophilic dye DiI to stain ICCs in the submucosal-circular ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051058
更新日期:1998-05-01 00:00:00
abstract::The freshwater polyp Hydra magnipapillata has a primitive nervous system that produces at least three distinct classes of neuropeptides: various peptides having the C-terminal sequence Arg-Phe-NH2 (the Hydra-RFamide family), Leu-Trp-NH2 (the Hydra-LWamide family), and a single peptide having the C-terminal sequence Ly...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000240
更新日期:2000-08-01 00:00:00
abstract::Mlh1 is a member of DNA mismatch repair (MMR) machinery and is also essential for the stabilization of crossovers during the first meiotic division. Recently, we have shown that zebrafish mlh1 mutant males are completely infertile because of a block in metaphase I, whereas females are fertile but have aneuploid progen...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0550-z
更新日期:2008-04-01 00:00:00
abstract::The application of autologous dermal fibroblasts has been shown to improve burn wound healing. However, a major hurdle is the availability of sufficient healthy skin as a cell source. We investigated fetal dermal cells as an alternative source for cell-based therapy for skin regeneration. Human (hFF), porcine fetal (p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-015-2293-6
更新日期:2016-04-01 00:00:00
abstract::This report describes a phenotyping study of differentiating human skeletal muscle cells in tissue culture. Satellite cells (adult myoblasts), isolated from biopsy material, showed a proliferative behaviour in high-nutrition medium, but fused to form myotubes when grown in low-nutrition medium. The expression and stru...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00381893
更新日期:1992-10-01 00:00:00
abstract::The fate of the major connective tissue polysaccharide hyaluronan, as it appears after release from the matrix, was studied in the Atlantic cod by use of subcutaneous administration of hyaluronan conjugated with fluorescein isothiocyanate (FITC) and labelled with 125I. After administration, the ligand was transported ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050912
更新日期:1997-10-01 00:00:00
abstract::In order to compare the functional state of the anterior pituitary of spontaneously hypertensive rats (SHR) with that of nonmotensive Wistar Kyoto rats (WKR), the anterior pituitary was examined by morphometry and autoradiography at the level of electron microscopy. The relative number and the relative volume of thyro...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00237005
更新日期:1979-10-01 00:00:00
abstract::Human endothelial progenitor cells (EPCs) were isolated from cord blood samples and enriched by magnetic activated cell sorting method based on the CD133 marker. Cells were incubated with different doses of bacterial lipopolysaccharide, ranging from 2, 5, 10, 50, 100, 200, 250, 500, to 1000 µg/ml, for 48 h. The cell s...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03405-4
更新日期:2021-01-18 00:00:00
abstract::The innervation of the uterus in the ovoviviparous urodele Salamandra salamandra was studied. In whole mount preparations of the thin-walled uterus of pregnant females, a dense adrenergic network was demonstrated using a modified glyoxylic acid fluorescence technique. Based on vesicle type and cytochemical reactivity ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213797
更新日期:1983-01-01 00:00:00
abstract::Rat endometrial explants were cultured in a three-dimensional collagen/endothelial cell matrix to measure angiogenic activity, as represented by migration of vascular endothelial cells towards the explants. Minimal endothelial cell migratory activity was observed with endometrial explants taken during the four-day oes...
journal_title:Cell and tissue research
pub_type: 历史文章,杂志文章
doi:10.1007/BF00300706
更新日期:1995-01-01 00:00:00
abstract::Rat blood monocytes contain granules of two types, primary and secondary granules, which can be distinguished on morphological grounds. Secondary granules have a halo between the limiting membrane and the matrix; primary granules have no halo and are generally more elongate than the secondary granules. In addition, th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00226665
更新日期:1977-11-30 00:00:00
abstract::In developing bioassays for estrogenic effects, vitellogenin (Vtg) induction and zona radiata protein (Zr-protein) induction in males and juveniles of oviparous vertebrates have been used as sensitive biomarkers for estrogenicity. Nonylphenol (NP) produces similar and parallel expression patterns of Vtg and Zr-protein...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0543-y
更新日期:2008-03-01 00:00:00
abstract::The oxyntic mucosa of the mammalian stomach is rich in endocrine cells, such as ECL cells, A-like cells, somatostatin cells, D1/P cells and, in some species, enterochromaffin cells. The various endocrine cell types can be distinguished on the basis of their characteristic cytoplasmic granules and vesicles. The ECL cel...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050707
更新日期:1996-12-01 00:00:00
abstract::The pineal organ of the eel, Anguilla anguilla was studied light-and electron-microscopically. The tissue consists predominantly of glia-like supporting cells and photoreceptor-like sensory cells, which establish synaptic contacts with pineal nerve cells. Histochemically, a positive acetylcholinesterase (AchE) reactio...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00238650
更新日期:1981-01-01 00:00:00
abstract::Four groups of male rats were exercised for periods of 2, 4, 6, and 8 weeks with controls in each group. As a result of chronic exercise there was an increase in the width of the zona fasciculata of the adrenal cortex. Also, there was an increase in the number and size of the mitochondria, and an increase in the quant...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215882
更新日期:1976-05-06 00:00:00
abstract::The globiferous pedicellariae of Psammechinus miliaris are described. Two fixation methods giving minimal distortion and rapid tissue hardening were adapted for soft tissue preparation for scanning electron microscopy. The pedicellarial valves are covered by a microvillous epithelium. The outer valve epithelial microv...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220184
更新日期:1975-10-13 00:00:00
abstract::Numerous nerve fibres containing acetylcholinesterase and noradrenaline, as well as avian pancreatic polypeptide-, vasoactive intestinal peptide-, or substance P-like immunoreactivity are observed around arteries in the external carotid rete of the cat. The nerves are located in the adventitial layer close to the medi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218360
更新日期:1982-01-01 00:00:00
abstract::Adult white-footed mice, Peromyscus leucopus, were kept either in long photoperiod (LP; LD 16:8) or in short photoperiod (SP; LD 8:16) for six weeks. Ovaries were serially sectioned and examined histologically. Preantral follicles were observed to release their oocyte into the ovarian stroma. This phenomenon is termed...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218373
更新日期:1982-01-01 00:00:00
abstract::The ultrastructural immunohistochemical localization of gamma aminobutyric acid (GABA) and its regulating enzymes, L-glutamate decarboxylase (GAD) and gamma aminobutyrate-alpha-ketoglutarate transaminase, was determined utilizing an immunogold post-embedding protocol in pancreatic exocrine tissue. Within the acinar ce...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213841
更新日期:1988-04-01 00:00:00
abstract::The distribution of neuropeptide Y (NPY)-like immunoreactivity in the brain of the bichir, Polypterus senegalus, was examined immunohistochemically. NPY-like immunoreactivity was distributed widely in the brain, with the highest density in the diencephalon. NPY-positive perikarya were found in various areas, including...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050874
更新日期:1997-08-01 00:00:00
abstract::The ultrastructural localisation of acid phosphatases (AcPhs) during the normal daily breakdown of rhabdomere membrane in Dinopis has been examined using beta-glycerophosphate and p-nitrophenyl phosphate as substrates. Results are related to the classification of organelles in the receptors given by Blest, Powell and ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236082
更新日期:1979-07-17 00:00:00
abstract::Corneal fibroblasts, major cellular components of the corneal stroma, are loosely arrayed between collagen lamellae. They play an important role in the metabolic and physiological homeostasis mechanisms by which the cornea is kept transparent. This paper deals with the demonstration of the gap junctions between the co...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215533
更新日期:1987-08-01 00:00:00