Abstract:
:It has been known for some 50 years that birds use photoreceptors in or near the hypothalamus to mediate the photoperiodic responses that control seasonal breeding. So far, however, attempts to identify the photopigment by determining an action spectrum have failed. The problems stem from the selective filtering of light by the tissues surrounding the photoreceptors and the need to deliver defined amounts of light over the days or weeks required to induce a quantitative measure of photostimulation. Here we have developed a technique which produces a quantitative action spectrum for the photoperiodic response in the Japanese quail; the results indicate the presence of a rhodopsin photopigment with a peak sensitivity of approximately 492 nm. The photoreceptors exhibit a level of sensitivity comparable with that of vertebrate visual pigments. We conclude that the brain photoreceptors of birds are based on a rhodopsin/rhodopsin-like photopigment.
journal_name
Naturejournal_title
Natureauthors
Foster RG,Follett BK,Lythgoe JNdoi
10.1038/313050a0subject
Has Abstractpub_date
1985-01-03 00:00:00pages
50-2issue
5997eissn
0028-0836issn
1476-4687journal_volume
313pub_type
杂志文章相关文献
NATURE文献大全abstract::A thermal light-emitting source, such as a black body or the incandescent filament of a light bulb, is often presented as a typical example of an incoherent source and is in marked contrast to a laser. Whereas a laser is highly monochromatic and very directional, a thermal source has a broad spectrum and is usually qu...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/416061a
更新日期:2002-03-07 00:00:00
abstract::Haematopoietic stem cells drive blood production, but their population size and lifetime dynamics have not been quantified directly in humans. Here we identified 129,582 spontaneous, genome-wide somatic mutations in 140 single-cell-derived haematopoietic stem and progenitor colonies from a healthy 59-year-old man and ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-018-0497-0
更新日期:2018-09-01 00:00:00
abstract::The first event in the initiation of an immune response is the capture and presentation of antigen to T cells. Such presentation involves two distinct steps: (1) display of the antigen, which requires uptake, processing and re-expression of the antigen in association with MHC molecules on the presenting cell surface; ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/334253a0
更新日期:1988-07-21 00:00:00
abstract::Molecular cloning and DNA sequencing have yielded considerable structural information about proenkephalin. All previously characterized intermediate peptides of the enkephalin pathways in bovine adrenal medulla have now been aligned into an unambiguous primary structure. Two basic amino acid residues serve as processi...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/295206a0
更新日期:1982-01-21 00:00:00
abstract::Human behaviour is thought to spread through face-to-face social networks, but it is difficult to identify social influence effects in observational studies, and it is unknown whether online social networks operate in the same way. Here we report results from a randomized controlled trial of political mobilization mes...
journal_title:Nature
pub_type: 杂志文章,随机对照试验
doi:10.1038/nature11421
更新日期:2012-09-13 00:00:00
abstract::Mecsas and colleagues suggest that a deficiency in the chemokine receptor CCR5 in humans is unlikely to confer protection against plague, based on their study of Yersinia pestis infection in Ccr5-deficient mice. They were testing the hypothesis that a mutation in the CCR5 gene, frequently found in Caucasians, may have...
journal_title:Nature
pub_type: 评论,杂志文章
doi:10.1038/nature02822
更新日期:2004-07-22 00:00:00
abstract::Defects in insulin signalling are among the most common and earliest defects that predispose an individual to the development of type 2 diabetes. MicroRNAs have been identified as a new class of regulatory molecules that influence many biological functions, including metabolism. However, the direct regulation of insul...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature10112
更新日期:2011-06-08 00:00:00
abstract::Long-term synaptic potentiation (LTP) is thought to be a key process in cortical synaptic network plasticity and memory formation. Hebbian forms of LTP depend on strong postsynaptic depolarization, which in many models is generated by action potentials that propagate back from the soma into dendrites. However, local d...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature13664
更新日期:2014-11-06 00:00:00
abstract::Triton is Neptune's principal satellite and is by far the largest retrograde satellite in the Solar System (its mass is approximately 40 per cent greater than that of Pluto). Its inclined and circular orbit lies between a group of small inner prograde satellites and a number of exterior irregular satellites with both ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature04792
更新日期:2006-05-11 00:00:00
abstract::Galactose oxidase is an extracellular enzyme secreted by the fungus Dactylium dendroides. It is monomeric, with a relative molecular mass of 68,000, catalyses the stereospecific oxidation of a broad range of primary alcohol substrates and possesses a unique mononuclear copper site essential for catalysing a two-electr...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/350087a0
更新日期:1991-03-07 00:00:00
abstract::Lipid-bilayer membranes supported on solid substrates are widely used as cell-surface models that connect biological and artificial materials. They can be placed either directly on solids or on ultrathin polymer supports that mimic the generic role of the extracellular matrix. The tools of modern genetic engineering a...
journal_title:Nature
pub_type: 杂志文章,评审
doi:10.1038/nature04164
更新日期:2005-09-29 00:00:00
abstract::Granular superconductivity occurs when microscopic superconducting grains are separated by non-superconducting regions; Josephson tunnelling between the grains establishes the macroscopic superconducting state. Although crystals of the copper oxide high-transition-temperature (high-Tc) superconductors are not granular...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/415412a
更新日期:2002-01-24 00:00:00
abstract::Sea-level histories during the two most recent deglacial-interglacial intervals show substantial differences1-3 despite both periods undergoing similar changes in global mean temperature4,5 and forcing from greenhouse gases6. Although the last interglaciation (LIG) experienced stronger boreal summer insolation forcing...
journal_title:Nature
pub_type: 历史文章,杂志文章
doi:10.1038/s41586-020-1931-7
更新日期:2020-01-01 00:00:00
abstract::Macrophages and dendritic cells have key roles in viral infections, providing virus reservoirs that frequently resist antiviral therapies and linking innate virus detection to antiviral adaptive immune responses. Human immunodeficiency virus 1 (HIV-1) fails to transduce dendritic cells and has a reduced ability to tra...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature10195
更新日期:2011-06-29 00:00:00
abstract::Efficient long-distance quantum teleportation is crucial for quantum communication and quantum networking schemes. Here we describe the high-fidelity teleportation of photons over a distance of 600 metres across the River Danube in Vienna, with the optimal efficiency that can be achieved using linear optics. Our resul...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/430849a
更新日期:2004-08-19 00:00:00
abstract::The biological importance of DNA methylation for gene expression in eukaryotes is becoming increasingly evident, and a direct role of methylation in gene expression has been suggested by an analysis of the infectivity of integrated retroviral genomes in a transfection assay. These studies, however, did not address whe...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/304275a0
更新日期:1983-07-21 00:00:00
abstract::The colonization of a new habitat is a fundamental process in metapopulation biology, but it is difficult to study. The emigration of colonists from established populations might be induced by resource competition owing to high local population density. Migration distances are also important because they determine the...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/416424a
更新日期:2002-03-28 00:00:00
abstract::In contrast to protein-coding sequences, the significance of variation in non-coding DNA in human disease has been minimally explored. A great number of recent genome-wide association studies suggest that non-coding variation is a significant risk factor for common disorders, but the mechanisms by which this variation...
journal_title:Nature
pub_type: 杂志文章,评审
doi:10.1038/nature08451
更新日期:2009-09-10 00:00:00
abstract::Predation can be intense, creating strong direct and indirect effects throughout food webs. In addition, ecologists increasingly recognize that fluxes of organisms across ecosystem boundaries can have major consequences for community dynamics. Species with complex life histories often shift habitats during their life ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature03962
更新日期:2005-10-06 00:00:00
abstract::Fast radio bursts (FRBs) are millisecond-duration radio transients1,2 of unknown origin. Two possible mechanisms that could generate extremely coherent emission from FRBs invoke neutron star magnetospheres3-5 or relativistic shocks far from the central energy source6-8. Detailed polarization observations may help us t...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-020-2827-2
更新日期:2020-10-01 00:00:00
abstract::The chemical induction of malignant transformation in BHK cells seems to result from a somatic mutation. Stable transformants, whose frequency is significantly increased by mutagenic carcinogens, can revert to normal and often display temperature-restricted phenotypes indicative of an altered gene product. ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/264722a0
更新日期:1976-12-23 00:00:00
abstract::Valuable information about proto-oncogenes and their physiological function has been obtained by studying their expression in normal cells. However, expression of the c-mos gene, the cellular homologue of the transforming gene of Moloney murine sarcoma virus, has not been detected in normal mouse cells or tissues. The...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/315516a0
更新日期:1985-06-06 00:00:00
abstract::Enhancers are cis-acting control elements which can stimulate at a distance the activity of a variety of eukaryotic promoters. First identified as a repeated 72 base pair (bp) sequence upstream of the simian virus 40 (SV40) early gene promoter, enhancers have since been shown to be associated with numerous other viral...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/313711a0
更新日期:1985-02-21 00:00:00
abstract::Concern about the levels of lead in blood is widespread. There is uncertainty, however, about the relative importance of the various environmental sources. Lead in petrol is widely assumed to be one of the most important sources and air and dust have been identified as the main routes to man. Water is regarded as an i...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/310138a0
更新日期:1984-07-12 00:00:00
abstract::There is evidence to suggest that components of archaebacteria are evolutionarily related to cognates in the eukaryotic cytosol. We postulated that the major heat-shock protein of the thermophilic archaebacterium, Sulfolobus shibatae, is a molecular chaperone and that it is related to an as-yet unidentified chaperone ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/354490a0
更新日期:1991-12-12 00:00:00
abstract::Many small proteins seem to fold by a simple process explicable by conventional chemical kinetics and transition-state theory. This assumes an instant equilibrium between reactants and a high-energy activated state. In reality, equilibration occurs on timescales dependent on the molecules involved, below which such an...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature01609
更新日期:2003-05-08 00:00:00
abstract::Colorectal cancer (CRC) is a heterogeneous disease of the intestinal epithelium that is characterized by the accumulation of mutations and a dysregulated immune response. Up to 90% of disease risk is thought to be due to environmental factors such as diet, which is consistent with a growing body of literature that des...
journal_title:Nature
pub_type: 杂志文章,评审
doi:10.1038/s41586-020-2729-3
更新日期:2020-09-01 00:00:00
abstract::Exploiters (parasites and predators) are thought to play a significant role in diversification, and ultimately speciation, of their hosts or prey. Exploiters may drive sympatric (within-population) diversification if there are a variety of exploiter-resistance strategies or fitness costs associated with exploiter resi...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature01164
更新日期:2002-12-05 00:00:00
abstract::The cell adhesion molecules L1, N-CAM and Ng-CAM have been implicated in cell-cell interactions among developing neural cells. L1 and N-CAM are structurally and functionally distinct molecular entities and act synergistically in mediating Ca2+-independent adhesion between re-aggregating early postnatal cerebellar cell...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/316728a0
更新日期:1985-08-22 00:00:00
abstract::Mechanical milling is an effective technique for the preparation of fine metallic and ceramic powders and can also be used to drive a wide range of chemical reactions. Milling devices include planetary machines, attritors and vibrational mills; products include amorphous, nanocrystalline and quasicrystalline materials...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature00985
更新日期:2002-09-12 00:00:00