Abstract:
:Granular superconductivity occurs when microscopic superconducting grains are separated by non-superconducting regions; Josephson tunnelling between the grains establishes the macroscopic superconducting state. Although crystals of the copper oxide high-transition-temperature (high-Tc) superconductors are not granular in a structural sense, theory suggests that at low levels of hole doping the holes can become concentrated at certain locations resulting in hole-rich superconducting domains. Granular superconductivity arising from tunnelling between such domains would represent a new view of the underdoped copper oxide superconductors. Here we report scanning tunnelling microscope studies of underdoped Bi2Sr2CaCu2O8+delta that reveal an apparent segregation of the electronic structure into superconducting domains that are approximately 3 nm in size (and local energy gap <50 meV), located in an electronically distinct background. We used scattering resonances at Ni impurity atoms as 'markers' for local superconductivity; no Ni resonances were detected in any region where the local energy gap Delta > 50 +/- 2.5 meV. These observations suggest that underdoped Bi2Sr2CaCu2O8+delta is a mixture of two different short-range electronic orders with the long-range characteristics of a granular superconductor.
journal_name
Naturejournal_title
Natureauthors
Lang KM,Madhavan V,Hoffman JE,Hudson EW,Eisaki H,Uchida S,Davis JCdoi
10.1038/415412akeywords:
subject
Has Abstractpub_date
2002-01-24 00:00:00pages
412-6issue
6870eissn
0028-0836issn
1476-4687pii
415412ajournal_volume
415pub_type
杂志文章相关文献
NATURE文献大全abstract::It has been established that many eukaryotic mRNAs contain poly(adenylic acid) tracts at their 3'-termini. The polyadenylation of mRNA occurs post-transcriptionally in the nucleus as a rapid, initial addition of 100-200 adenylate residues to the pre-mRNA (ref. 1). Subsequently, a slower chain extension (6-8 bases) of ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/267178a0
更新日期:1977-05-12 00:00:00
abstract::Valuable information about proto-oncogenes and their physiological function has been obtained by studying their expression in normal cells. However, expression of the c-mos gene, the cellular homologue of the transforming gene of Moloney murine sarcoma virus, has not been detected in normal mouse cells or tissues. The...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/315516a0
更新日期:1985-06-06 00:00:00
abstract::Non-insulin-dependent diabetes mellitus (NIDDM) is a major health problem, affecting 5% of the world population. Genetic factors are important in NIDDM, but the mechanisms leading to glucose intolerance are unknown. Genetic linkage has been investigated in multigeneration families to localize, and ultimately identify,...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/356162a0
更新日期:1992-03-12 00:00:00
abstract::Angiotensin II is an important effector molecule controlling blood pressure and volume in the cardiovascular system. Its importance is manifested by the efficacy of angiotensin-converting enzyme inhibitors in the treatment of hypertension and congestive heart failure. Angiotensin II interacts with two pharmacologicall...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/351233a0
更新日期:1991-05-16 00:00:00
abstract::Haptic (touch) perception normally entails an active exploration of object surfaces over time. This is called active touch. When exploring the shape of an object, we experience both geometrical and force cues. For example, when sliding a finger across a surface with a rigid bump on it, the finger moves over the bump w...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35086588
更新日期:2001-07-26 00:00:00
abstract::The spindle checkpoint prevents chromosome mis-segregation by delaying sister chromatid separation until all chromosomes have achieved bipolar attachment to the mitotic spindle. Its operation is essential for accurate chromosome segregation, whereas its dysregulation can contribute to birth defects and tumorigenesis. ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature05694
更新日期:2007-04-19 00:00:00
abstract::Devices that convert information from one form into another according to a definite procedure are known as automata. One such hypothetical device is the universal Turing machine, which stimulated work leading to the development of modern computers. The Turing machine and its special cases, including finite automata, o...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35106533
更新日期:2001-11-22 00:00:00
abstract::The observations that atherosclerosis often occurs in non-smokers without elevated levels of low-density lipoprotein cholesterol, and that most atherosclerosis loci so far identified in mice do not affect systemic risk factors associated with atherosclerosis, suggest that as-yet-unidentified mechanisms must contribute...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature03527
更新日期:2005-05-26 00:00:00
abstract::The sequencing of ancient DNA has enabled the reconstruction of speciation, migration and admixture events for extinct taxa1. However, the irreversible post-mortem degradation2 of ancient DNA has so far limited its recovery-outside permafrost areas-to specimens that are not older than approximately 0.5 million years (...
journal_title:Nature
pub_type: 历史文章,杂志文章
doi:10.1038/s41586-019-1555-y
更新日期:2019-10-01 00:00:00
abstract::Mice of the AKR strain are characterised by a high incidence of spontaneous thymic lymphomas. AKR chromosomes contain the genomes of ecotropic murine leukaemia virus (MuLV) at two loci, termed Akv-1 and Akv-2 (refs 2-6). Shortly after birth, the normal tissues of AKR mice begin to produce high levels of this XC-positi...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/282753a0
更新日期:1979-12-13 00:00:00
abstract::The cyc- variants of S49 lymphoma cells have served as powerful tools for studying the components and mechanisms of hormone-induced adenylate cyclase stimulation, as these cells are deficient in the guanine nucleotide regulatory site (Ns) mediating hormone, guanine nucleotide, cholera toxin and fluoride-induced stimul...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/303177a0
更新日期:1983-05-12 00:00:00
abstract::The potential use of smallpox as a biological weapon has led to the production and stockpiling of smallpox vaccine and the immunization of some healthcare workers. Another public health goal is the licensing of a safer vaccine that could benefit the millions of people advised not to take the current one because they o...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature02331
更新日期:2004-03-11 00:00:00
abstract::Arid ecosystems, which occupy about 20% of the earth's terrestrial surface area, have been predicted to be one of the most responsive ecosystem types to elevated atmospheric CO2 and associated global climate change. Here we show, using free-air CO2 enrichment (FACE) technology in an intact Mojave Desert ecosystem, tha...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35040544
更新日期:2000-11-02 00:00:00
abstract::Sex differences in behaviour extend to cognitive-like processes such as learning, but the underlying dimorphisms in neural circuit development and organization that generate these behavioural differences are largely unknown. Here we define at the single-cell level-from development, through neural circuit connectivity,...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature15700
更新日期:2015-10-15 00:00:00
abstract::Interstellar dust plays a crucial role in the evolution of the Universe by assisting the formation of molecules, by triggering the formation of the first low-mass stars, and by absorbing stellar ultraviolet-optical light and subsequently re-emitting it at infrared/millimetre wavelengths. Dust is thought to be produced...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature02930
更新日期:2004-09-30 00:00:00
abstract::Mutations in the p53 tumour-suppressor gene are the most frequently observed genetic lesions in human cancers. To investigate the role of the p53 gene in mammalian development and tumorigenesis, a null mutation was introduced into the gene by homologous recombination in murine embryonic stem cells. Mice homozygous for...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/356215a0
更新日期:1992-03-19 00:00:00
abstract::Combined analyses of gene networks and DNA sequence variation can provide new insights into the aetiology of common diseases that may not be apparent from genome-wide association studies alone. Recent advances in rat genomics are facilitating systems-genetics approaches. Here we report the use of integrated genome-wid...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature09386
更新日期:2010-09-23 00:00:00
abstract::Animal microRNAs (miRNAs) regulate gene expression by inhibiting translation and/or by inducing degradation of target messenger RNAs. It is unknown how much translational control is exerted by miRNAs on a genome-wide scale. We used a new proteomic approach to measure changes in synthesis of several thousand proteins i...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature07228
更新日期:2008-09-04 00:00:00
abstract::Y chromosomes underlie sex determination in mammals, but their repeat-rich nature has hampered sequencing and associated evolutionary studies. Here we trace Y evolution across 15 representative mammals on the basis of high-throughput genome and transcriptome sequencing. We uncover three independent sex chromosome orig...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature13151
更新日期:2014-04-24 00:00:00
abstract::The spatial organization of the genome is intimately linked to its biological function, yet our understanding of higher order genomic structure is coarse, fragmented and incomplete. In the nucleus of eukaryotic cells, interphase chromosomes occupy distinct chromosome territories, and numerous models have been proposed...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature11082
更新日期:2012-04-11 00:00:00
abstract::Graphene oxide membranes-partially oxidized, stacked sheets of graphene-can provide ultrathin, high-flux and energy-efficient membranes for precise ionic and molecular sieving in aqueous solution. These materials have shown potential in a variety of applications, including water desalination and purification, gas and ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature24044
更新日期:2017-10-19 00:00:00
abstract::Since the discovery of superconductivity in the high-transition-temperature (high-T(c)) copper oxides two decades ago, it has been firmly established that the CuO(2) plane is essential for superconductivity and gives rise to a host of other very unusual properties. A new family of superconductors with the general comp...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature07081
更新日期:2008-06-26 00:00:00
abstract::The complete knowledge of a quantum state allows the prediction of the probability of all possible measurement outcomes, a crucial step in quantum mechanics. It can be provided by tomographic methods which have been applied to atomic, molecular, spin and photonic states. For optical or microwave photons, standard tomo...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature13821
更新日期:2014-10-30 00:00:00
abstract::Bacterial pathogens trigger specialized virulence factor secretion systems on encountering host cells. The ESX-1 protein secretion system of Mycobacterium tuberculosis-the causative agent of the human disease tuberculosis-delivers bacterial proteins into host cells during infection and is critical for virulence, but h...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature07219
更新日期:2008-08-07 00:00:00
abstract::When present in single-stranded DNA, palindromic or quasi-palindromic sequences have the potential to form complex secondary structures, including hairpins, which may facilitate interstrand misalignment of direct repeats and be responsible for diverse types of replication-based mutations, including deletions, addition...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/352544a0
更新日期:1991-08-08 00:00:00
abstract::Cloning and sequencing of the complementary DNA for platelet-derived endothelial cell growth factor indicates that it is a novel factor distinct from previously characterized proteins. The factor, a protein with a relative molecular mass of about 45,000, stimulates endothelial cell growth and chemotaxis in vitro and a...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/338557a0
更新日期:1989-04-13 00:00:00
abstract::XX female mammals undergo transcriptional silencing of most genes on one of their two X chromosomes to equalize X-linked gene dosage with XY males in a process referred to as X-chromosome inactivation (XCI). XCI is an example of epigenetic regulation. Once enacted in individual cells of the early female embryo, XCI is...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature08161
更新日期:2009-07-30 00:00:00
abstract::Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis largely owing to inefficient diagnosis and tenacious drug resistance. Activation of pancreatic stellate cells (PSCs) and consequent development of dense stroma are prominent features accounting for this aggressive biology1,2. The reciprocal interplay betwe...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-019-1130-6
更新日期:2019-05-01 00:00:00
abstract::The growth cycle in nutrient-rich, aquatic environments starts with a diatom bloom that ends in mass sinking of ungrazed cells and phytodetritus. The low grazing pressure on these blooms has been attributed to the inability of overwintering copepod populations to track them temporally. We tested an alternative explana...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature02526
更新日期:2004-05-27 00:00:00
abstract::The enzyme complex nitrogenase, which reduces N2 to NH+4, involves two redox proteins, both irreversibly damaged by O2 (ref. 1). Enzyme activity therefore requires anaerobic conditions, a source of reductant and a large amount of ATP (approximately 16 ATPs per N2). In both aerobic and facultative anaerobic N2-fixing b...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/290424a0
更新日期:1981-04-02 00:00:00