Abnormal muscle mitochondria in ischemic claudication.

Abstract:

:The gastrocnemius and quadriceps muscles findings in 18 patients with chronic arterial insufficiency were reviewed with regard to mitochondrial changes. Prominent mitochondrial alterations were present in eight out of 18 patients. The comparison of clinical data between patients with and without mitochondrial changes revealed that in this latter group all patients were at stage IV, whereas the degree of ischemic disease was milder in the other group: the difference in distribution of patients at stage IV between the two groups was statistically significant. This supports the view that mitochondrial changes are expression of adaptive modification rather than damage.

journal_name

Acta Neurol Belg

journal_title

Acta neurologica Belgica

authors

Marbini A,Gemignani F,Scoditti U,Rustichelli P,Bragaglia MM,Govoni E

subject

Has Abstract

pub_date

1986-11-01 00:00:00

pages

304-10

issue

5

eissn

0300-9009

issn

2240-2993

journal_volume

86

pub_type

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