Subchronic treatment of rats with nicotine: effects on tolerance and on [3H]acetylcholine and [3H]nicotine binding in the brain.

abstract：:While current psychiatric taxonomies recognise a classification of amphetamine dependence, derived from the notion of an alcohol dependence syndrome, little research has validated that such a condition exists for this drug. Current amphetamine users (N = 331), were interviewed using the World Health Organization opera...

journal_title：Drug and alcohol dependence

authors： Topp L,Darke S

更新日期：1997-11-25 00:00:00

abstract：OBJECTIVES:Point-of-care drug checking services, wherein individuals can check the content and purity of their drugs, have emerged as a public health intervention to address the fentanyl crisis; however, there have been no rigorous evaluations of the technologies against reference standard laboratory techniques. METHO...

journal_title：Drug and alcohol dependence

authors： Ti L,Tobias S,Lysyshyn M,Laing R,Nosova E,Choi J,Arredondo J,McCrae K,Tupper K,Wood E

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Despite increasing rates of opioid misuse and hospitalizations, rates of treatment for those with opioid use disorder (OUD) are very low. This study examined the impact of the Patient Protection and Affordable Care Act's (ACA) insurance expansion on improving rates of insurance, health care access, and tre...

journal_title：Drug and alcohol dependence

authors： McKenna RM

更新日期：2017-10-01 00:00:00

abstract：:Diagnostic concordance of DSM-III, DSM-IV and ICD-10 was tested in a heterogeneous unrestricted sample of 370 clinical cases drawn from a regional consortium. Agreement for abuse/harmful use, dependence, and the collapsed category of 'any diagnosis' was studied across eight drug classes. A probabilistic approach to th...

journal_title：Drug and alcohol dependence

authors： Langenbucher J,Morgenstern J,Labouvie E,Nathan PE

更新日期：1994-12-01 00:00:00

abstract：:A group of adolescent drug "experimenters" as defined by the frequency of use (N = 496) were compared to non-users (N = 2417) and to "regular" users (N = 125) on a number of variables. These covered the patterns of use, attitudes to drug use, exposure to drugs and to drug use, and other behavioural correlates. Experim...

journal_title：Drug and alcohol dependence

authors： Swadi H

更新日期：1990-10-01 00:00:00

abstract：:Social context may be an important determinant of drug and alcohol consumption and HIV-related behaviors. To assess the influence of peers on drug users' risk behaviors this study examined the association between individual level and group level behaviors. This analysis reports on the prospective association between b...

journal_title：Drug and alcohol dependence

authors： Latkin CA,Mandell W,Vlahov D

更新日期：1996-11-01 00:00:00

abstract：AIMS:The Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) is a screening instrument to detect substance use in primary care (PC). To screen for illicit substances (excluding tobacco and alcohol), the ASSIST consists of 8-57 questions and requires complicated scoring. To improve the efficiency of scree...

journal_title：Drug and alcohol dependence

authors： Tiet QQ,Leyva Y,Moos RH,Smith B

更新日期：2016-07-01 00:00:00

abstract：INTRODUCTION:Exposure to child maltreatment is associated with elevated risk for behavioral disorders in adulthood. One explanation for this life-course association is that child maltreatment increases vulnerability to the effects of subsequent stressors; however, the extent to which maltreatment increases sensitivity ...

journal_title：Drug and alcohol dependence

authors： Keyes KM,McLaughlin KA,Koenen KC,Goldmann E,Uddin M,Galea S

更新日期：2012-04-01 00:00:00

abstract：:There is a considerable disparity between the number of individuals who need substance abuse treatment and the number who actually receive it. This is partly due to the fact that many individuals with substance use disorders do not perceive a need for formal treatment. Another contributing factor, however, is a discre...

journal_title：Drug and alcohol dependence

authors： McCollister KE,French MT,Pyne JM,Booth B,Rapp R,Carr C

更新日期：2009-10-01 00:00:00

abstract：:Halazepam administered chronically to dogs in oral doses of 180 and 450 mg/kg/day produced physical dependence which was revealed by a flumazenil precipitated abstinence syndrome and measured by the Nordiazepam Precipitated Abstinence Scale score (NPAS) (McNicholas et al., 1988; Sloan et al., 1990). This abstinence as...

journal_title：Drug and alcohol dependence

authors： Sloan JW,Martin WR,Wala E,Dickey KM

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:To examine the characteristics of "diagnostic orphans" among cannabis users - those who report one or two symptoms of DSM-IV dependence but do not meet diagnostic criteria for DSM-IV abuse or dependence - 4 years post-assessment. METHOD:Data were collected from a representative population cohort of young Aus...

journal_title：Drug and alcohol dependence

authors： Degenhardt L,Coffey C,Carlin JB,Swift W,Patton GC

更新日期：2008-01-01 00:00:00

abstract：:There have been relatively few studies of genetic factors in drug abuse. Childhood Attention Deficit Hyperactivity Disorder (ADHD) has been implicated as a risk factor, and pedigree studies of Tourette Syndrome (TS), a hereditary impulse disorder closely related to ADHD, show an increased prevalence of substance abuse...

journal_title：Drug and alcohol dependence

authors： Comings DE

更新日期：1994-03-01 00:00:00

abstract：:What contributes to sustained abstinence from injection drug use by those who participate in community-based Narcotics Anonymous (NA) and Alcoholics Anonymous (AA) is not well understood. We know that sponsorship is a central element in these programs. To investigate the relationship between sponsorship and abstinence...

journal_title：Drug and alcohol dependence

authors： Crape BL,Latkin CA,Laris AS,Knowlton AR

更新日期：2002-02-01 00:00:00

abstract：:Interest in oral fluid as an alternative matrix for monitoring drug use is due to its ease-of-collection and non-invasiveness; however, limited data are available on the disposition of drugs into oral fluid. The objective of this research was to provide data on the presence and concentrations of heroin, cocaine and mu...

journal_title：Drug and alcohol dependence

authors： Dams R,Choo RE,Lambert WE,Jones H,Huestis MA

更新日期：2007-03-16 00:00:00

abstract：:Impulsivity appears to play an important role in suicidal behaviors and drug abuse, which are two psychiatric problems that may interact with one another. Interpretation of the literature on impulsivity in these behaviors may be complicated by the variety of measurement techniques for the assessment of impulsivity. Th...

journal_title：Drug and alcohol dependence

authors： Dougherty DM,Mathias CW,Marsh DM,Moeller FG,Swann AC

更新日期：2004-12-07 00:00:00

abstract：:Flunitrazepam was evaluated in several procedures that have been used extensively to study the behavioral effects and abuse potential of positive GABA(A) modulators. One group of monkeys (n=3) responded to receive injections of methohexital or saline (i.v.) while other groups (n=2-4/group) discriminated vehicle from e...

journal_title：Drug and alcohol dependence

authors： Gerak LR,Woolverton WL,Nader MA,Patrick GA,Harris LS,Winger G,Woods JH,France CP

更新日期：2001-06-01 00:00:00

abstract：:Administrative data provide a rich resource for improving our understanding of individuals with substance use disorders. The validation of administrative proxies for moderate or high risk alcohol or drug (AOD) use could enhance the ability to carry out rigorous observational research (for example, for use in the const...

journal_title：Drug and alcohol dependence

authors： Sears JM,Krupski A,Joesch JM,Estee SL,He L,Shah MF,Huber A,Dunn C,Ries R,Roy-Byrne PP

更新日期：2010-09-01 00:00:00

abstract：:Heroin is an illicit narcotic abused by millions of people worldwide. In our earlier studies we have shown that heroin intoxication changes the antioxidant status in human brain. In the present work we continued our studies by estimating the effect of heroin abuse on reduced glutathione (GSH) and enzymes related to th...

journal_title：Drug and alcohol dependence

authors： Gutowicz M,Kaźmierczak B,Barańczyk-Kuźma A

更新日期：2011-01-01 00:00:00

abstract：:Background Psychiatry inpatients frequently have co-occurring substance use and mental health disorders, which are related to poor post-discharge outcomes. Telephone monitoring is effective in specialty substance use disorder treatment settings in increasing continuing care and 12-step program utilization and improvin...

journal_title：Drug and alcohol dependence

authors： Timko C,Harris AHS,Jannausch M,Ilgen M

更新日期：2019-01-01 00:00:00

abstract：AIM:To assess whether substance-abusing people have a higher risk of dying from unintentional acute intoxication in specific periods of the year. METHODS:A total of 15,792 deaths (males=14,259; females=1533) were ascertained to be due to unintentional acute intoxication by illicit drugs in Italy in the study period (1...

journal_title：Drug and alcohol dependence

authors： Rocchi MB,Miotto P,Preti A

更新日期：2003-10-24 00:00:00

abstract：BACKGROUND:Adolescents tend to overestimate the prevalence of substance use among their peers and these perceived norms are associated with their current and future use. However, little is known about how perceived norms change over time during middle school, a developmental period when adolescents are at-risk for init...

journal_title：Drug and alcohol dependence

authors： Pedersen ER,Miles JN,Ewing BA,Shih RA,Tucker JS,D'Amico EJ

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To examine the characteristics of 'diagnostic orphans' among cannabis users-those who report one or two symptoms of DSM-IV dependence but do not meet diagnostic criteria for DSM-IV abuse or dependence. METHOD:Data were collected from a representative population cohort of 1601 young adults aged 20-21 years. T...

journal_title：Drug and alcohol dependence

authors： Degenhardt L,Lynskey M,Coffey C,Patton G

更新日期：2002-07-01 00:00:00

abstract：:In this discussion of contributed papers for the special issue of DAD, the author draws attention to early American laws concerning cannabis and to statements made about the epidemiology of cannabis smoking and other drug use between 1858 and the contemporary scene, with coverage of opium, heroin, tobacco, alcohol, co...

journal_title：Drug and alcohol dependence

authors： Anthony JC

更新日期：2012-06-01 00:00:00

abstract：:The purpose of this study was to clarify the extent of neuropsychological impairment previously found among amphetamine users (McKetin and Mattick, 1997) by comparing them with a non-drug-using control group. Amphetamine users who were classified as low dependence (n = 15) or high dependence (n = 11) according to the ...

journal_title：Drug and alcohol dependence

authors： McKetin R,Mattick RP

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:As part of a randomized controlled trial, problem drinkers who recently initiated natural recovery on their own were offered access to an interactive voice response (IVR) self-monitoring (SM) system as a sobriety maintenance tool during early recovery when relapse risk is high. Because observed IVR utilizati...

journal_title：Drug and alcohol dependence

authors： Simpson CA,Huang J,Roth DL,Chandler SD,Tucker JA

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to test the hypothesis that desipramine would be an effective treatment in cocaine abusers with current depressive disorders. METHOD:This was a randomized, 12-week, double-blind, 'placebo-controlled trial of outpatients (N = 111) meeting DSM-III-R criteria for cocaine dependence and...

journal_title：Drug and alcohol dependence

authors： McDowell D,Nunes EV,Seracini AM,Rothenberg J,Vosburg SK,Ma GJ,Petkova E

更新日期：2005-11-01 00:00:00

abstract：:Diagnostic interviews for substance use disorders tend to have high reliability among adults. We examined the inter-rater reliability of the substance use disorders section of the Structured Clinical Interview for the DSM, using 46 male and 25 female adolescent drinkers recruited from community and treatment sources. ...

journal_title：Drug and alcohol dependence

authors： Martin CS,Pollock NK,Bukstein OG,Lynch KG

更新日期：2000-05-01 00:00:00

abstract：:Contingency management (CM) is an evidence-based treatment, and clinicians are beginning to implement this intervention in practice. However, little research exists on methods for assuring appropriate implementation of CM. This study describes the development and psychometric properties of the 12-item CM Competence Sc...

journal_title：Drug and alcohol dependence

authors： Petry NM,Alessi SM,Ledgerwood DM,Sierra S

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:American Indians and Alaska Natives (AI/ANs) have high rates of tobacco use compared to the general population. AI/ANs also have elevated rates of psychiatric and substance use disorders associated with nicotine dependence. However, very few studies have examined the comorbidity between nicotine dependence a...

journal_title：Drug and alcohol dependence

authors： Moghaddam JF,Dickerson DL,Yoon G,Westermeyer J

更新日期：2014-11-01 00:00:00

abstract：:This paper has three foci. First, it examines the developing area of clinical sociology. Second, it demonstrates how, in reality, deviants in general and drug addicts in particular should be treated using theories of deviance and symbolic interactionism. The treatment itself is based on group experiences and is geared...

journal_title：Drug and alcohol dependence

authors： Ben-Yehuda N

更新日期：1984-05-01 00:00:00