Desipramine treatment of cocaine-dependent patients with depression: a placebo-controlled trial.

abstract：BACKGROUND:We previously reported that when long-term abstinent alcoholics (LTAA; with no drug comorbidity) are compared to controls, they show increased resting state synchrony (RSS) in the executive control network and reduced RSS in the appetitive drive network suggestive of compensatory mechanisms that may facilita...

journal_title：Drug and alcohol dependence

authors： Camchong J,Stenger VA,Fein G

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Homelessness and substance use often coexist, resulting in high morbidity. Emergency department (ED) patients have disproportionate rates of both homelessness and substance use, yet little research has examined the overlap of these issues in the ED setting. We aimed to characterize alcohol and drug use in a ...

journal_title：Drug and alcohol dependence

authors： Doran KM,Rahai N,McCormack RP,Milian J,Shelley D,Rotrosen J,Gelberg L

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Buprenorphine/naloxone (BUP/NX), an effective treatment for opioid dependence, has been implicated in hepatic toxicity. However, as persons taking BUP/NX have multiple hepatic risk factors, comparative data are needed to quantify the risk of hepatoxicity with BUP/NX. METHODS:We compared rates of alanine ami...

journal_title：Drug and alcohol dependence

authors： Lucas GM,Young A,Donnell D,Richardson P,Aramrattana A,Shao Y,Ruan Y,Liu W,Fu L,Ma J,Celentano DD,Metzger D,Jackson JB,Burns D,HPTN 058 study group.

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The U.S. prevalence of misuse of prescription opioid analgesics has increased substantially over the past decade but research on the factors influencing misuse of these medications remains preliminary. In the literature on alcohol, marijuana and stimulants, substance-related expectancies have been found to p...

journal_title：Drug and alcohol dependence

authors： Ilgen MA,Roeder KM,Webster L,Mowbray OP,Perron BE,Chermack ST,Bohnert AS

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:There is some debate whether smoking during pregnancy causes or is only a risk factor for negative academic outcomes and increased risk of psychopathology in offspring. This study evaluated whether maternal smoking cessation would reduce the risk of adverse outcomes in school-aged children. METHODS:Women co...

journal_title：Drug and alcohol dependence

authors： Piper BJ,Gray HM,Birkett MA

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:With the emergence of illicit fentanyl, fentanyl-involved overdose rates increased from 2013 to 2017 in the United States (US). We describe US trends in opioid-related overdose mortality rates by race, age, urbanicity, and opioid type before and after the emergence of fentanyl. METHODS:Using the Centers for...

journal_title：Drug and alcohol dependence

authors： Althoff KN,Leifheit KM,Park JN,Chandran A,Sherman SG

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Patients with prescription opioid use disorder commonly report relief of chronic pain as the chief reason for first opioid use; indeed, the prevalence of chronic pain is high in this population. Understanding the association between pain severity and subsequent opioid use is crucial for understanding how to ...

journal_title：Drug and alcohol dependence

authors： Griffin ML,McDermott KA,McHugh RK,Fitzmaurice GM,Jamison RN,Weiss RD

更新日期：2016-06-01 00:00:00

abstract：:This paper aims to outline some of the caveats inherent in studies on first and second messengers in the central nervous system as related to tolerance and dependence. Analysis of systems based on measures of first and second messengers may be an over-simplification, since the actual molecular consequences of neurotra...

journal_title：Drug and alcohol dependence

authors： Siggins GR

更新日期：1979-05-01 00:00:00

abstract：INTRODUCTION:Exposure to child maltreatment is associated with elevated risk for behavioral disorders in adulthood. One explanation for this life-course association is that child maltreatment increases vulnerability to the effects of subsequent stressors; however, the extent to which maltreatment increases sensitivity ...

journal_title：Drug and alcohol dependence

authors： Keyes KM,McLaughlin KA,Koenen KC,Goldmann E,Uddin M,Galea S

更新日期：2012-04-01 00:00:00

abstract：:Drug usage patterns among patients admitted to a Swedish clinic specialized in the treatment of drug dependence have undergone significant changes during the last fifteen years. During this period there has been a decline in amphetamine taking and a rise in opiate abuse. Yearly cohorts of drug abusers were subjected t...

journal_title：Drug and alcohol dependence

authors： Frykholm B

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:There is growing recognition regarding the clinical importance of integrating smoking cessation services, such as nicotine replacement therapy (NRT), within programs that treat substance use disorders (SUDs) since the majority of individuals receiving treatment also smoke. Previous research has not examined ...

journal_title：Drug and alcohol dependence

authors： Knudsen HK,Studts JL

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Concurrent alcohol use and waterpipe (WP) smoking is common among young adults. WP smokers are more than twice as likely to use alcohol as non-users and frequently consume alcohol immediately before and during a WP smoking session. It is unclear what impact alcohol has on WP smoking patterns and res...

journal_title：Drug and alcohol dependence

authors： Leavens EL,Brett EI,Frank S,Shaikh RA,Leffingwell TR,Croff JM,Wagener TL

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Females exhibit more rapid escalation of cocaine use and enhanced cocaine-taking behavior as compared to males. While ovarian hormones likely play a role in this increased vulnerability, research has yet to examine the role of estradiol in affecting the behavioral and neurological response to cocaine in a br...

journal_title：Drug and alcohol dependence

authors： Cummings JA,Jagannathan L,Jackson LR,Becker JB

更新日期：2014-02-01 00:00:00

abstract：:To determine whether differences in life styles and patterns of drug use may help to account for willingness to try heroin and/or likelihood of becoming addicted, personal history interviews were conducted with 15 young heroin addict, 15 experimenters who used the drug but did not become addicts, and 15 nonusers who n...

journal_title：Drug and alcohol dependence

authors： Crawford GA

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:Few studies have examined clinical trial participation rates and treatment outcomes among underserved young adults who are dependent on marijuana, the most commonly abused illicit drug. METHOD:The present study was a secondary analysis of a trial of court-referred marijuana-dependent young adults (ages 18-2...

journal_title：Drug and alcohol dependence

authors： Montgomery L,Petry NM,Carroll KM

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:In order to successfully address excessive alcohol consumption it is essential to have a means of measuring the drinking patterns of a nation. Owing to the multi-dimensional nature of drinking patterns, usual survey methods have their limitations. The aim of this study was to make use of extremely detailed d...

journal_title：Drug and alcohol dependence

authors： Hill-McManus D,Angus C,Meng Y,Holmes J,Brennan A,Sylvia Meier P

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Men who have sex with men (MSM) who use crystal methamphetamine (CM) are at increased risk for HIV infection. Post-exposure prophylaxis (PEP) is a useful HIV prevention strategy if individuals are able to identify high-risk exposures and seek timely care, however to date there has been limited data on the us...

journal_title：Drug and alcohol dependence

authors： Oldenburg CE,Jain S,Mayer KH,Mimiaga MJ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:North Carolina, like much of the U.S. South, is disproportionately affected by HIV and hepatitis. This persistently high disease burden may be driven in part by laws that criminalize the possession and distribution of syringes for illicit drug use. Legal change to decriminalize syringes may reduce infection ...

journal_title：Drug and alcohol dependence

authors： Davis CS,Johnston J,de Saxe Zerden L,Clark K,Castillo T,Childs R

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The ability to predict potential for relapse to substance use following treatment could be very useful in targeting aftercare strategies. Recently, a number of investigators have focused on using neural activity measured by fMRI to predict relapse propensity. The purpose of the present study was to use fMRI ...

journal_title：Drug and alcohol dependence

authors： Prisciandaro JJ,Myrick H,Henderson S,McRae-Clark AL,Brady KT

更新日期：2013-07-01 00:00:00

abstract：:A series of beta-carbolines were prepared and their affinities for imidazoline (I(1) and I(2)) sites evaluated. Selected compounds were also examined at alpha(2)-adrenoceptors. Some of the beta-carbolines were found to bind with high affinity to I(2)-sites and this affinity was dependent on both the planarity of the m...

journal_title：Drug and alcohol dependence

authors： Husbands SM,Glennon RA,Gorgerat S,Gough R,Tyacke R,Crosby J,Nutt DJ,Lewis JW,Hudson AL

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Contingency management (CM) is efficacious for reducing drug use, but it has rarely been applied to patients with severe and persistent mental health problems. This study evaluated the efficacy of CM for reducing cocaine use in psychiatric patients treated at a community mental health center. METHODS:Ninete...

journal_title：Drug and alcohol dependence

authors： Petry NM,Alessi SM,Rash CJ

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Few studies have assessed the temporal association between homelessness and injection drug use, and injection-related risk behavior. METHODS:Among a cohort of 1405 current and former injection drug users in follow-up from 2005 to 2009, we used random intercept models to assess the temporal association betwe...

journal_title：Drug and alcohol dependence

authors： Linton SL,Celentano DD,Kirk GD,Mehta SH

更新日期：2013-10-01 00:00:00

abstract：:Sprague-Dawley rats were intoxicated with alcohol or morphine, by ingestion in a fluid diet. Alcohol or morphine preference was studied in two-bottle choice tests. Preference increased up to a certain level with increasing time of intoxication at one dose level. Some 10% of the animals had an extremely high preference...

journal_title：Drug and alcohol dependence

authors： Rönnbäck L

更新日期：1988-07-01 00:00:00

abstract：:Little is known about the relative severity or typical sequence of Diagnostic and Statistical Manual (DSM-IV) symptoms of nicotine dependence. Using data from the National Comorbidity Study (NCS), the current study used a Rasch logistic item response model to assess the unidimensionality of the construct of nicotine d...

journal_title：Drug and alcohol dependence

authors： Strong DR,Kahler CW,Ramsey SE,Brown RA

更新日期：2003-11-24 00:00:00

abstract：BACKGROUND:Cross-sectional studies have demonstrated gender-related differences in the associations between problem-gambling severity and substance-use disorders; however, these associations have not been examined longitudinally. We aimed to examine the prospective associations between problem-gambling severity and inc...

journal_title：Drug and alcohol dependence

authors： Pilver CE,Libby DJ,Hoff RA,Potenza MN

更新日期：2013-11-01 00:00:00

abstract：:A sample of 175 individuals were interviewed and divided in three subgroups of couples: (1) the husband was in an Anonymous Alcoholics program, (2) the husband had been diagnosed as alcoholic and (3) the husband had a regular pattern of high alcohol consumption. In personal interviews by specialized personnel the foll...

journal_title：Drug and alcohol dependence

authors： Natera G,Herrejón ME,Casco M

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Smoking of synthetic cannabinoid-enhanced "herbal incense" is an emerging substance abuse problem. The indole-derived cannabinoids identified in these products were originally developed as research tools and are structurally distinct from cannabinoids in the cannabis plant. Although abused by humans, most pu...

journal_title：Drug and alcohol dependence

authors： Wiley JL,Marusich JA,Martin BR,Huffman JW

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Prior research shows that cannabis use during treatment for Alcohol Use Disorders (AUD) is related to fewer abstinent days from alcohol, although only among those who use cannabis 1-2x/month. Here we extend prior research by assessing the relationship between the frequency of cannabis use during AUD treatmen...

journal_title：Drug and alcohol dependence

authors： Subbaraman MS,Metrik J,Patterson D,Stout RL

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:As a response to mounting overdose fatalities, cross-agency outreach efforts have emerged to reduce future risk among overdose survivors. We aimed to characterize such programs in Massachusetts, with focus on team composition, approach, services provided, and funding. METHODS:We conducted a two-phase cross-...

journal_title：Drug and alcohol dependence

authors： Formica SW,Waye KM,Benintendi AO,Yan S,Bagley SM,Beletsky L,Carroll JJ,Xuan Z,Rosenbloom D,Apsler R,Green TC,Hunter A,Walley AY

更新日期：2021-02-01 00:00:00

abstract：:The pharmaceutical industry has made substantial innovations in the area of targeted drug delivery and optimization of pharmacokinetics for existing drugs to try to maximize therapeutic effect while simultaneously minimizing adverse consequences of medication abuse. These innovations, however, have not come without a ...

journal_title：Drug and alcohol dependence

authors： McCormick CG

更新日期：2006-06-01 00:00:00