Are diagnostic orphans at risk of developing cannabis abuse or dependence? Four-year follow-up of young adult cannabis users not meeting diagnostic criteria.

Abstract:

OBJECTIVE:To examine the characteristics of "diagnostic orphans" among cannabis users - those who report one or two symptoms of DSM-IV dependence but do not meet diagnostic criteria for DSM-IV abuse or dependence - 4 years post-assessment. METHOD:Data were collected from a representative population cohort of young Australian adults. Those who reported that they had used cannabis at least weekly at some point within the past year were assessed for symptoms of DSM-IV cannabis abuse and dependence using the Composite International Diagnostic Interview at age 20-21 years. The entire sample was followed up 4 years later. At age 24-25 years, cannabis use and cannabis diagnostic category were examined according to diagnostic category at age 20-21 years. RESULTS:Diagnostic orphans at age 20-21 years were more likely than non-problem cannabis users at that age to be using cannabis, and to meet criteria for cannabis abuse or dependence 4 years later. Those who had met criteria for cannabis abuse or dependence, however, appeared to be at greater risk relative to non-problematic users and diagnostic orphans of meeting criteria for cannabis abuse and dependence at follow-up. CONCLUSIONS:Young adult diagnostic orphans for cannabis use appear to be at lower risk of meeting full (or partial) diagnostic criteria after a 4-year follow-up, compared to those who had met criteria for cannabis abuse or dependence. This suggests that there is prognostic diagnostic utility in the threshold for dependence symptoms among young adult cannabis users. Diagnostic orphans did appear to be at greater risk than non-problem users for developing dependent and daily cannabis use, however, suggesting that clinicians would do well to intervene with this group.

journal_name

Drug Alcohol Depend

authors

Degenhardt L,Coffey C,Carlin JB,Swift W,Patton GC

doi

10.1016/j.drugalcdep.2007.07.003

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

86-90

issue

1-3

eissn

0376-8716

issn

1879-0046

pii

S0376-8716(07)00273-6

journal_volume

92

pub_type

杂志文章
  • Naltrexone shortened opioid detoxification with buprenorphine.

    abstract::This double-blind, randomized, placebo-controlled clinical trial evaluated the impact on withdrawal symptoms of (i) combining naltrexone with a 4-day buprenorphine taper for short opioid detoxification (NB Group), compared to (ii) using a 4-day buprenorphine taper alone, followed by naltrexone on day 8 (PB Group). Sub...

    journal_title:Drug and alcohol dependence

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0376-8716(99)00033-2

    authors: Umbricht A,Montoya ID,Hoover DR,Demuth KL,Chiang CT,Preston KL

    更新日期:1999-10-01 00:00:00

  • Latent class analysis of polysubstance use, sexual risk behaviors, and infectious disease among South African drug users.

    abstract:BACKGROUND:HIV transmission risk among non-injection drug users is high due to the co-occurrence of drug use and sexual risk behaviors. The purpose of the current study was to identify patterns of drug use among polysubstance users within a high HIV prevalence population. METHODS:The study sample included 409 substanc...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2013.03.004

    authors: Trenz RC,Scherer M,Duncan A,Harrell PT,Moleko AG,Latimer WW

    更新日期:2013-10-01 00:00:00

  • Genetic factors in substance abuse based on studies of Tourette syndrome and ADHD probands and relatives. I. Drug abuse.

    abstract::There have been relatively few studies of genetic factors in drug abuse. Childhood Attention Deficit Hyperactivity Disorder (ADHD) has been implicated as a risk factor, and pedigree studies of Tourette Syndrome (TS), a hereditary impulse disorder closely related to ADHD, show an increased prevalence of substance abuse...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(94)90104-x

    authors: Comings DE

    更新日期:1994-03-01 00:00:00

  • Mechanisms of change in extended cognitive behavioral treatment for tobacco dependence.

    abstract:AIM:To evaluate potential mediators of an extended cognitive behavioral smoking cessation intervention. DESIGN:Analysis of data from a randomized clinical trial of smoking cessation. SETTING:The Habit Abatement Clinic, University of California, San Francisco. PARTICIPANTS:Participants were older cigarette smokers (>...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2009.12.021

    authors: Hendricks PS,Delucchi KL,Hall SM

    更新日期:2010-06-01 00:00:00

  • Michigan Alcoholism Screening Test (MAST)--its possibilities and shortcomings as a screening device in a pre-selected non-clinical population.

    abstract::A statistical analysis of the MAST scores obtained by its administration to industrial workers, hospitalized alcoholics and persons arrested driving while intoxicated has been performed. The author discusses the modalities and possibilities of improving the test reliability which will increase its efficiency in the sc...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(89)90064-1

    authors: Tulevski IG

    更新日期:1989-12-01 00:00:00

  • Changes in short-term prognosis-a comparison between Swedish amphetamine and opiate abusers.

    abstract::Drug usage patterns among patients admitted to a Swedish clinic specialized in the treatment of drug dependence have undergone significant changes during the last fifteen years. During this period there has been a decline in amphetamine taking and a rise in opiate abuse. Yearly cohorts of drug abusers were subjected t...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(80)90188-x

    authors: Frykholm B

    更新日期:1980-02-01 00:00:00

  • Socio-ecological factors associated with depression, suicidal ideation and suicidal attempt among female injection drug users who are sex workers in China.

    abstract:OBJECTIVE:Female injection drug users who are also sex workers (FSW-IDUs) occupy a pivotal population in HIV transmission, whereas their mental health problems are largely overlooked. We aimed to investigate prevalence and associated socio-ecological factors of depression, suicidal ideation and suicidal attempts among ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2014.08.011

    authors: Gu J,Lau JT,Li M,Li H,Gao Q,Feng X,Bai Y,Hao C,Hao Y

    更新日期:2014-11-01 00:00:00

  • Recreational marijuana legalization and prescription opioids received by Medicaid enrollees.

    abstract:OBJECTIVES:Medical marijuana use may substitute prescription opioid use, whereas nonmedical marijuana use may be a risk factor of prescription opioid misuse. This study examined the associations between recreational marijuana legalization and prescription opioids received by Medicaid enrollees. METHODS:State-level qua...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2018.09.016

    authors: Shi Y,Liang D,Bao Y,An R,Wallace MS,Grant I

    更新日期:2019-01-01 00:00:00

  • Carisoprodol tolerance and precipitated withdrawal.

    abstract:AIMS:Carisoprodol is a muscle relaxant that acts at the GABA(A) receptor. Concerns about the abuse liability of carisoprodol are increasing, but evidence that carisoprodol produces tolerance and a significant withdrawal syndrome has yet to be established. The purpose of the current study was to determine if repeated ad...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2011.10.010

    authors: Gatch MB,Nguyen JD,Carbonaro T,Forster MJ

    更新日期:2012-06-01 00:00:00

  • Pragmatic randomized controlled trial of a web-based intervention for alcohol use among Brazilian college students: Motivation as a moderating effect.

    abstract:BACKGROUND:Web-based personalized normative feedback (PNF) interventions are less effective than their laboratory versions. Participant motivation may account for this reduced effect, but there is only a limited amount of research into the influence of motivation on PNF effectiveness. We evaluated the effectiveness of ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2019.02.021

    authors: Bedendo A,Ferri CP,de Souza AAL,Andrade ALM,Noto AR

    更新日期:2019-06-01 00:00:00

  • Evaluation of TSPO PET imaging, a marker of glial activation, to study the neuroimmune footprints of morphine exposure and withdrawal.

    abstract:INTRODUCTION:A growing area of research suggests that neuroimmunity may impact the pharmacology of opioids. Microglia is a key component of the brain immunity. Preclinical and clinical studies have demonstrated that microglial modulators may improve morphine-induced analgesia and prevent the development of tolerance an...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2016.10.037

    authors: Auvity S,Goutal S,Thézé B,Chaves C,Hosten B,Kuhnast B,Saba W,Boisgard R,Buvat I,Cisternino S,Tournier N

    更新日期:2017-01-01 00:00:00

  • Patterns and correlates of attempted suicide by heroin users over a 3-year period: findings from the Australian treatment outcome study.

    abstract::In order to determine patterns and correlates of attempted suicide amongst heroin users across 3 years, a cohort of 387 heroin users (134 entering maintenance treatment, 134 entering detoxification, 81 entering residential rehabilitation and 38 not entering treatment) were interviewed about suicide attempts at baselin...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.drugalcdep.2006.08.010

    authors: Darke S,Ross J,Williamson A,Mills KL,Havard A,Teesson M

    更新日期:2007-03-16 00:00:00

  • Screening for current drug use disorders in alcoholics: an application of receiver operating characteristic analysis.

    abstract::The major objectives of the present study were 2-fold: (1) to demonstrate the superiority of receiver operating characteristic (ROC) methodology in the comparison of screening tests that yield continuous values; and (2) to identify the best screening indicator of current drug use disorders in alcoholics. We evaluated ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(88)90056-7

    authors: Grant BF,Hasin DS,Harford TC

    更新日期:1988-05-01 00:00:00

  • Maternal alcohol use during pregnancy and offspring trajectories of height and weight: A prospective cohort study.

    abstract:BACKGROUND:Previous studies have examined associations between alcohol use in pregnancy and offspring birth size but evidence on whether associations persist during childhood is limited. METHODS:We examined the association between maternal drinking during pregnancy and trajectories of offspring weight and height from ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2015.02.035

    authors: O'Keeffe LM,Kearney PM,Greene RA,Zuccolo L,Tilling K,Lawlor DA,Howe LD

    更新日期:2015-08-01 00:00:00

  • Factors associated with history of non-fatal overdose among young nonmedical users of prescription drugs.

    abstract:OBJECTIVES:The current study examines the prevalence and correlates of lifetime non-fatal overdose (OD) involving the nonmedical use of prescription opioids and tranquilizers among a sample of high-risk young adults in New York, NY and Los Angeles, CA. METHODS:Data were derived from a cross-sectional study of 16-25 ye...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2012.08.014

    authors: Silva K,Schrager SM,Kecojevic A,Lankenau SE

    更新日期:2013-02-01 00:00:00

  • Lower rates of consistent urine drug tests for prescribed psychotropic medications among patients on opioid replacement therapy.

    abstract:BACKGROUND:Patients on opioid replacement therapy (ORT) to treat opioid use disorder are frequently monitored for these medications, but it is not known if they are also adhering to their psychotropic medications. This is an analysis of measure of potential adherence to psychotropic medications by patients on ORT. MET...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2016.08.632

    authors: Hassan AN

    更新日期:2016-11-01 00:00:00

  • Perceived risk of harm and intentions of future inhalant use among adolescent inhalant users.

    abstract:OBJECTIVE:To identify predictors of perceived (a) risk of harm associated with inhalant use and (b) intention to use inhalants among adolescent inhalant users. METHOD:Participants were 279 lifetime inhalant users (M(age)=15.5, 84% male) identified in a statewide survey of 723 adolescents in Missouri Division of Youth ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2008.04.005

    authors: Perron BE,Howard MO

    更新日期:2008-09-01 00:00:00

  • A randomized trial of contingency management for adolescent marijuana abuse and dependence.

    abstract::An initial efficacy test of an innovative behavioral outpatient treatment model for adolescents with problematic use of marijuana enrolled 69 adolescents, aged 14-18, and randomly assigned them to one of two treatment conditions. Both conditions received individualized Motivational Enhancement and Cognitive Behavioral...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2009.07.009

    authors: Stanger C,Budney AJ,Kamon JL,Thostensen J

    更新日期:2009-12-01 00:00:00

  • Propylhexdrine.

    abstract::Propylhexedrine, a sympathomimetic with varied medicinal uses, is one of the compounds to be reviewed by the Expert Committee convened by the World Health Organization (WHO) to determine whether the compound should be scheduled under the Convention on Psychotropic Substances. This paper reviews the pharmacology, medic...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(86)90013-x

    authors: Wesson DR

    更新日期:1986-06-01 00:00:00

  • Comparison of categorical alcohol dependence versus a dimensional measure for predicting weekly alcohol use in heavy drinkers.

    abstract:BACKGROUND:The DSM specifies categorical criteria for psychiatric disorders. In contrast, a dimensional approach considers variability in symptom severity and can significantly improve statistical power. The current study tested whether a categorical, DSM-defined diagnosis of Alcohol Dependence (AD) was a better fit th...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2013.12.020

    authors: Fazzino TL,Rose GL,Burt KB,Helzer JE

    更新日期:2014-03-01 00:00:00

  • High rates of police detention among recently released HIV-infected prisoners in Ukraine: implications for health outcomes.

    abstract:BACKGROUND:Ukraine's HIV epidemic, primarily affecting people who inject drugs (PWID), is expanding and transitioning despite free opioid substitution therapy (OST) and antiretroviral therapy (ART), two effective ways to reduce HIV transmission. Police detention of PWID not resulting in a formal charge or imprisonment ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2013.05.018

    authors: Izenberg JM,Bachireddy C,Soule M,Kiriazova T,Dvoryak S,Altice FL

    更新日期:2013-11-01 00:00:00

  • Opioid-related overdose mortality in the era of fentanyl: Monitoring a shifting epidemic by person, place, and time.

    abstract:BACKGROUND:With the emergence of illicit fentanyl, fentanyl-involved overdose rates increased from 2013 to 2017 in the United States (US). We describe US trends in opioid-related overdose mortality rates by race, age, urbanicity, and opioid type before and after the emergence of fentanyl. METHODS:Using the Centers for...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2020.108321

    authors: Althoff KN,Leifheit KM,Park JN,Chandran A,Sherman SG

    更新日期:2020-11-01 00:00:00

  • Detecting smoking following smoking cessation treatment.

    abstract::Our study compared the results of self-report (SR) plus breath carbon monoxide (CO) monitoring to SR plus urine cotinine (COT) analysis of recent tobacco use for a recently completed smoking cessation study that compared the efficacy of different intensities of psychosocial treatments coupled with 8 weeks of patch tre...

    journal_title:Drug and alcohol dependence

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0376-8716(01)00162-4

    authors: Gariti P,Alterman AI,Ehrman R,Mulvaney FD,O'Brien CP

    更新日期:2002-01-01 00:00:00

  • The drug problem in the Federal Republic of Germany.

    abstract::The new 'Betäubungsmittelgesetz' (Narcotic drugs law) of the Federal Republic of Germany is analyzed from the viewpoint of punishment vs. treatment. ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(85)90010-9

    authors: Müller B

    更新日期:1985-08-01 00:00:00

  • Early-onset of illicit substance use is associated with greater axis-II comorbidity, not with axis-I comorbidity.

    abstract::In the present study the relationship between early-onset (

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/s0376-8716(99)00132-5

    authors: Franken IH,Hendriks VM

    更新日期:2000-06-01 00:00:00

  • Effects of acute combined serotonin and dopamine depletion on cue-induced drinking intention/desire and cognitive function in patients with alcohol dependence.

    abstract:BACKGROUND:Alcohol cues can precipitate the desire to drink and cause relapse in recovering alcohol-dependent patients. Serotonin and dopamine may play a role in alcohol cue-induced craving. Acute combined tryptophan (Trp), tyrosine (Tyr), and phenylalanine (Phe) depletion (CMD) in the diet attenuates the synthesis of ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2012.01.006

    authors: Sun HQ,Liu Y,Li P,Bao YP,Sheng LX,Zhang RL,Cao YJ,Di XL,Yang FD,Wang F,Luo YX,Lu L

    更新日期:2012-08-01 00:00:00

  • Metabolic phenotype of rats exposed to heroin and potential markers of heroin abuse.

    abstract:BACKGROUND:Metabolomics allows the high-throughput analysis of low molecular mass compounds in biofluids, which can reflect the metabolic response of the body to heroin exposure and potentially reveal biomarkers of heroin abuse. METHODS:Heroin was administered to Sprague-Dawley rats in increasing doses from 3 to 16.5 ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2012.06.031

    authors: Zheng T,Liu L,Aa J,Wang G,Cao B,Li M,Shi J,Wang X,Zhao C,Gu R,Zhou J,Xiao W,Yu X,Sun R,Zhou Y,Zuo Y,Zhu X

    更新日期:2013-01-01 00:00:00

  • Development and psychometric properties of the Verona Service Satisfaction Scale for methadone-treated opioid-dependent patients (VSSS-MT).

    abstract::We adapted the 32-item Verona Service Satisfaction Scale (VSSS-32) to assess opioid-dependent patient satisfaction with services received from methadone treatment centres. The preliminary version of the VSSS for methadone treatment (VSSS-MT) was filled out anonymously and completed by 516 randomly recruited patients. ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/s0376-8716(02)00196-5

    authors: de los Cobos J,Valero S,Haro G,Fidel G,Escuder G,Trujols J,Valderrama JC

    更新日期:2002-10-01 00:00:00

  • The Network for the Improvement of Addiction Treatment (NIATx): enhancing access and retention.

    abstract::The Network for the Improvement of Addiction Treatment (NIATx) teaches participating treatment centers to use process improvement strategies. A cross-site evaluation monitored impacts on days between first contact and first treatment and percent of patients who started treatment and completed two, three and four units...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.drugalcdep.2006.10.009

    authors: McCarty D,Gustafson DH,Wisdom JP,Ford J,Choi D,Molfenter T,Capoccia V,Cotter F

    更新日期:2007-05-11 00:00:00

  • Oral fluid as an alternative matrix to monitor opiate and cocaine use in substance-abuse treatment patients.

    abstract::Interest in oral fluid as an alternative matrix for monitoring drug use is due to its ease-of-collection and non-invasiveness; however, limited data are available on the disposition of drugs into oral fluid. The objective of this research was to provide data on the presence and concentrations of heroin, cocaine and mu...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2006.08.020

    authors: Dams R,Choo RE,Lambert WE,Jones H,Huestis MA

    更新日期:2007-03-16 00:00:00