Bacteriophage Mu-induced modification of DNA is dependent upon a host function.

Abstract:

:The DNA of bacteriophage Mu, extracted from induced lysates, is partially resistant to digestion by the endonuclease BalI. This modification of DNA is controlled by the Mu modification function (mom), which acts in conjunction with the dam (DNA-adenine methylation) function of Escherichia coli. Since the BalI recognition site is apparently different from the dam recognition site, these results imply that either the specificity of the dam function is changed by the mom function or the mom function requires the dam function for its activity.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Khatoon H,Bukhari AI

doi

10.1128/JB.136.1.423-428.1978

subject

Has Abstract

pub_date

1978-10-01 00:00:00

pages

423-8

issue

1

eissn

0021-9193

issn

1098-5530

journal_volume

136

pub_type

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