Abstract:
:Glomeruli isolated from rat kidney cortex were incubated with adenosine in the presence or absence of verapamil and calcium and their change in cross-sectional area was recorded. Adenosine induced a 10% decrease in glomerular cross-sectional area. This decrease was blocked by verapamil or a calcium-free medium. The results suggest that the effect of adenosine in the kidney could be due to glomerular constriction, and that this constriction depends on the entry of calcium into glomerular cells.
journal_name
Eur J Pharmacoljournal_title
European journal of pharmacologyauthors
López-Novoa JM,de Arriba G,Barrio V,Rodriguez-Puyol Ddoi
10.1016/0014-2999(87)90371-2subject
Has Abstractpub_date
1987-02-24 00:00:00pages
365-7issue
3eissn
0014-2999issn
1879-0712pii
0014-2999(87)90371-2journal_volume
134pub_type
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