Solubilization and characterization of surface antigenic components of Erysipelothrix rhusiopathiae T28.

abstract：:Peptide 9 (TDAYNQKLSERRAN) and peptide 10 (NATAEGRAINRRVE) represent surface-exposed epitopes of outer membrane protein F of Pseudomonas aeruginosa. Rats immunized with four intramuscular inoculations on days 0, 14, 28, and 42 with either peptide 9 or peptide 10 conjugated to keyhole limpet hemocyanin were afforded pr...

journal_title：Infection and immunity

authors： Gilleland LB,Gilleland HE Jr

更新日期：1995-06-01 00:00:00

abstract：:A battery of lymphoid and nonlymphoid cells was examined for susceptibility to lysis by natural killer cells of chickens. Several susceptible targets were recognized, and most susceptible among these were cells of line LSCC-RP9, derived from a lymphoid tumor induced by Rous-associated virus 2. The natural killer react...

journal_title：Infection and immunity

authors： Sharma JM,Okazaki W

更新日期：1981-03-01 00:00:00

abstract：:Humoral immune responses in experimental African trypanosomiasis were assessed in rabbits infected with Trypanosoma rhodesiense. Immune complexes as measured by a Clq binding assay or a Clq solid-phase assay were detected by day 10 and increased progressively through day 28. Immune complexes analyzed by double diffusi...

journal_title：Infection and immunity

authors： Lindsley HB,Janecek LL,Gilman-Sachs AM,Hassanein KM

更新日期：1981-08-01 00:00:00

abstract：:Phase 1 and 2 clinical trials of group B streptococcal (GBS) capsular polysaccharide (CPS)-protein conjugate vaccines in healthy adults have demonstrated their safety and improved immunogenicity compared with uncoupled CPSs. Two recent trials sought to determine (i) whether adsorption of conjugate vaccine to aluminum ...

journal_title：Infection and immunity

authors： Paoletti LC,Rench MA,Kasper DL,Molrine D,Ambrosino D,Baker CJ

更新日期：2001-11-01 00:00:00

abstract：:In this study, we examined the binding of Candida albicans synchronized yeast-phase cells to plastic, immobilized amino acids and bovine serum albumin (BSA) and quantified the binding by using an XTT tetrazolium salt assay and absorbance determination. Our results show that C. albicans binds efficiently and specifical...

journal_title：Infection and immunity

authors： Hawser SP,Islam K

更新日期：1998-01-01 00:00:00

abstract：:Thirty percent of Streptococcus pneumoniae isolates contain pilus islet 1, coding for a pilus composed of the backbone subunit RrgB and two ancillary proteins, RrgA and RrgC. RrgA is the major determinant of in vitro adhesion associated with pilus 1, is protective in vivo in mouse models, and exists in two variants (c...

journal_title：Infection and immunity

authors： Moschioni M,Emolo C,Biagini M,Maccari S,Pansegrau W,Donati C,Hilleringmann M,Ferlenghi I,Ruggiero P,Sinisi A,Pizza M,Norais N,Barocchi MA,Masignani V

更新日期：2010-12-01 00:00:00

abstract：:Mice were vaccinated with plasmid DNA (pDNA) encoding antigen 85A (Ag85A), Ag85B, or PstS-3 from Mycobacterium tuberculosis either in saline or formulated for intramuscular injections in VC1052:DPyPE (aminopropyl-dimethyl-myristoleyloxy-propanaminium bromide-diphytanoylphosphatidyl-ethanolamine) (Vaxfectin; Vical, Inc...

journal_title：Infection and immunity

authors： D'Souza S,Rosseels V,Denis O,Tanghe A,De Smet N,Jurion F,Palfliet K,Castiglioni N,Vanonckelen A,Wheeler C,Huygen K

更新日期：2002-07-01 00:00:00

abstract：:Vaccination with native full-length merozoite surface protein 1 (MSP1) or with recombinant C-terminal peptides protects mice against lethal challenge with virulent malaria parasites. To determine whether other regions of MSP1 can also induce protection, Plasmodium yoelii MSP1 was divided into four separate regions. Ea...

journal_title：Infection and immunity

authors： Tian JH,Kumar S,Kaslow DC,Miller LH

更新日期：1997-08-01 00:00:00

abstract：:By using the powerful separation technique of capillary gas chromatography combined with the selectivity of mass spectrometric detection, muramic acid was not detectable in purified elementary bodies of Chlamydia psittaci Cal 10 (less than or equal to 0.006%) or C. trachomatis serovar E (less than or equal to 0.02%). ...

journal_title：Infection and immunity

authors： Fox A,Rogers JC,Gilbart J,Morgan S,Davis CH,Knight S,Wyrick PB

更新日期：1990-03-01 00:00:00

abstract：:Placenta-sequestering Plasmodium falciparum involved in the pathogenesis of pregnancy-associated malaria (PAM) in otherwise clinically immune women expresses particular variant surface antigens (VSA(PAM)) on the surface of infected erythrocytes that differ from VSA found in parasitized nonpregnant individuals (non-PAM...

journal_title：Infection and immunity

authors： Megnekou R,Staalsoe T,Taylor DW,Leke R,Hviid L

更新日期：2005-07-01 00:00:00

abstract：:Seven antigens of Borrelia hermsii, B. parkeri, and B. turicatae with isoelectric points in the range of 4.4 to 5.0 and molecular masses of 40 to 43 kilodaltons played a role in the relapse phenomenon of relapsing fever. Based upon location of the antigens in the outer envelope, the molecular weight, and Western blot ...

journal_title：Infection and immunity

authors： Kehl KS,Farmer SG,Komorowski RA,Knox KK

更新日期：1986-12-01 00:00:00

abstract：:Nonimmune binding of immunoglobulin to whole bacteria was quantitated for North American isolates of Haemophilus somnus recovered from cattle with pneumonia, reproductive failure (abortion), or thromboembolic meningoencephalitis or from the vagina or prepuce of carrier cattle. Quantitative binding activity covered a w...

journal_title：Infection and immunity

authors： Widders PR,Dorrance LA,Yarnall M,Corbeil LB

更新日期：1989-02-01 00:00:00

abstract：:The ScpC protease of Streptococcus pyogenes degrades interleukin-8 (IL-8), a chemokine that mediates neutrophil transmigration and activation. The ability to degrade IL-8 differs dramatically among clinical isolates of S. pyogenes. Bacteria expressing ScpC overcome immune clearance by preventing the recruitment of neu...

journal_title：Infection and immunity

authors： Sjölinder H,Lövkvist L,Plant L,Eriksson J,Aro H,Jones A,Jonsson AB

更新日期：2008-09-01 00:00:00

abstract：:Of 202 captive hares studied, many of which had lesions on their external genital organs or testicular atrophy or both, 27% had positive serological tests for syphilis although dark-field examination of extracts of atrophic testes was negative. A total of 12 hares that were nonreactive for the serological test for syp...

journal_title：Infection and immunity

authors： Horvath I,Kemenes F,Molnar L,Szeky A,Racz I

更新日期：1980-01-01 00:00:00

abstract：:The purpose of this investigation was to examine gamma interferon potentiation of lipopolysaccharide (LPS) responses in human monocytes by using phenol-water-extracted (unfractionated) and highly purified LPS preparations isolated from Bacteroides intermedius and Salmonella typhimurium. Phenol-water-extracted LPS prep...

journal_title：Infection and immunity

authors： Nichols FC,Peluso JF,Tempro PJ,Garrison SW,Payne JB

更新日期：1991-01-01 00:00:00

abstract：:Genetically based natural resistance to brucellosis in cattle provides for novel strategies to control zoonotic diseases. Bovine NRAMP1, the homologue of a murine gene (Bcg), has been identified as a major candidate for controlling the in vivo resistant phenotype. We developed an in vitro model for expression of resis...

journal_title：Infection and immunity

authors： Barthel R,Feng J,Piedrahita JA,McMurray DN,Templeton JW,Adams LG

更新日期：2001-05-01 00:00:00

abstract：:We describe here a Sprague-Dawley rat model for chronic osteomyelitis. Staphylococcus aureus and sodium morrhuate were implanted by either microdrilling or direct needle injection into the tibiae of rats. Of 107 rats, 87 (81%) developed osteomyelitis when a high-speed drill was used for implantation, and 27 (51%) of 5...

journal_title：Infection and immunity

authors： Rissing JP,Buxton TB,Weinstein RS,Shockley RK

更新日期：1985-03-01 00:00:00

abstract：:Ehrlichia chaffeensis, a tick-transmitted obligate intracellular rickettsial agent, causes human monocytic ehrlichiosis. In recent reports, we described substantial advances in developing random and targeted gene disruption methods to investigate the functions of E. chaffeensis genes. We reported earlier that the Hima...

journal_title：Infection and immunity

authors： Wang Y,Nair ADS,Alhassan A,Jaworski DC,Liu H,Trinkl K,Hove P,Ganta CK,Burkhardt N,Munderloh UG,Ganta RR

更新日期：2020-09-18 00:00:00

abstract：:The opportunistic pathogen Pseudomonas aeruginosa is a major cause of sepsis in severely burned patients. If it is not eradicated from the wound, it translocates to the bloodstream, causing sepsis, multiorgan failure, and death. We recently described the P. aeruginosa heparinase-encoding gene, hepP, whose expression w...

journal_title：Infection and immunity

authors： Dzvova N,Colmer-Hamood JA,Griswold JA,Hamood AN

更新日期：2017-12-19 00:00:00

abstract：:A modified version of the Bacteroides fragilis transposon Tn4400, designated Tn4400', enabling rapid isolation and analysis of B. fragilis mutants has been constructed. To identify potential virulence factors, Tn4400'-generated mutants were screened by a new method; this resulted in the isolation of 21 mutant strains ...

journal_title：Infection and immunity

authors： Tang YP,Malamy MH

更新日期：2000-01-01 00:00:00

abstract：:Vibrio cholerae accessory colonization factor genes (acfA, B, C, and D) are required for efficient intestinal colonization. Expression of acf genes is under the control of a regulatory cascade that also directs the synthesis of cholera toxin and proteins involved in the biogenesis of the toxin-coregulated pilus. The g...

journal_title：Infection and immunity

authors： Everiss KD,Hughes KJ,Kovach ME,Peterson KM

更新日期：1994-08-01 00:00:00

abstract：:Controversy persists over the role that the capsular polysaccharide plays in the pathogenesis of Staphylococcus aureus infections. To address this issue, we compared the mouse virulence of S. aureus Reynolds and capsule-defective mutant strains cultivated under conditions of high or low capsule expression. Strain Reyn...

journal_title：Infection and immunity

authors： Thakker M,Park JS,Carey V,Lee JC

更新日期：1998-11-01 00:00:00

abstract：:The type III secretion system (T3SS) encoded by the Salmonella pathogenicity island 2 (SPI2) has a central role in systemic infections by Salmonella enterica and for the intracellular phenotype. Intracellular S. enterica uses the SPI2-encoded T3SS to translocate a set of effector proteins into the host cell, which mod...

journal_title：Infection and immunity

authors： Hansen-Wester I,Chakravortty D,Hensel M

更新日期：2004-05-01 00:00:00

abstract：:It was demonstrated that complement-coated sheep erythrocytes bind to Candida albicans cells grown in serum-free RPMI 1640 medium. Testing of purified complement components proved that iC3b and C3d were responsible for the reaction, whereas C3b and C3b-H reacted only slightly if at all. Binding occurred only to C. alb...

journal_title：Infection and immunity

authors： Heidenreich F,Dierich MP

更新日期：1985-11-01 00:00:00

abstract：:The inhibition by Mycoplasma dispar of ciliary activity of organ cultures of bovine fetal trachea was found to be dependent on the presence of serum in the maintenance medium. Inhibitory activity was unaffected by catalase and no toxic substance was demonstrated in organ culture supernatant fluid. ...

journal_title：Infection and immunity

authors： Howard CJ,Thomas LH

更新日期：1974-08-01 00:00:00

abstract：:Apical membrane antigen 1 (AMA-1) is an invasion-related Plasmodium antigen that is expressed during both intracellular and extracellular asexual stages of the parasite's life cycle, making it an ideal target for induction of humoral and cellular immune responses that can protect against malaria. We show here that whe...

journal_title：Infection and immunity

authors： Bouillet LÉ,Dias MO,Dorigo NA,Moura AD,Russell B,Nosten F,Renia L,Braga EM,Gazzinelli RT,Rodrigues MM,Soares IS,Bruna-Romero O

更新日期：2011-09-01 00:00:00

abstract：:Salmonella enterica serovar Enteritidis is a major cause of food-borne diseases associated with consumption of shell eggs. Clinical isolates of S. enterica serovar Enteritidis exhibit a wide spectrum of virulence in mice. A highly virulent isolate (SE2472) was previously shown to be more resistant in vitro than other ...

journal_title：Infection and immunity

authors： Lu S,Killoran PB,Fang FC,Riley LW

更新日期：2002-02-01 00:00:00

abstract：:Mycoplasma genitalium is a sexually transmitted pathogen associated with several acute and chronic reproductive tract disease syndromes in men and women. To evaluate the suitability of a pig-tailed macaque model of M. genitalium infection, we inoculated a pilot animal with M. genitalium strain G37 in the uterine cervi...

journal_title：Infection and immunity

authors： Wood GE,Iverson-Cabral SL,Patton DL,Cummings PK,Cosgrove Sweeney YT,Totten PA

更新日期：2013-08-01 00:00:00

abstract：:We have previously shown that infection by Trypanosoma cruzi, a parasitic protozoan, is reduced by injection of CD40 ligand (CD40L)-transfected 3T3 fibroblasts (D. Chaussabel, F. Jacobs, J. de Jonge, M. de Veerman, Y. Carlier, K. Thielemans, M. Goldman, and B. Vray, Infect. Immun. 67:1929-1934, 1999). This prompted us...

journal_title：Infection and immunity

authors： Chamekh M,Vercruysse V,Habib M,Lorent M,Goldman M,Allaoui A,Vray B

更新日期：2005-10-01 00:00:00

abstract：:Actinobacillus pleuropneumoniae serotype 7 strains are shown to spontaneously lose cytolytic activity with a frequency of approximately 10(-4). The phenotypic change is associated with the loss of approximately 8.5 kbp of chromosomal DNA. A genomic fragment encoding the cytolysin and its flanking sequences was cloned ...

journal_title：Infection and immunity

authors： Anderson C,Potter AA,Gerlach GF

更新日期：1991-11-01 00:00:00