Bacteroides fragilis is a silent pathogen in acute appendicitis.

Abstract:

:The role of Bacteroides fragilis in the pathogenesis of acute appendicitis was studied in 135 patients in four patient groups: normal (17); phlegmonous appendicitis (17); gangrenous appendicitis (75); and septic complications of appendicitis (26). Aerobic and anaerobic bacteria were isolated from all groups and members of the 'B. fragilis group' were the most common anaerobic isolates. The rate of isolation of B. fragilis was similar from normal and inflamed appendices but was significantly higher from those with septic complications (p less than 0.01). Antibodies against B. fragilis were demonstrated in patients of all groups and occurred with similar frequencies in patients with normal and inflamed appendices but at a significantly higher rate in those with septic complications (p less than 0.01). Whereas patients in this latter group showed IgM-antibody responses to B. fragilis only, those with acute appendicitis had IgM antibodies against a wide range of organisms of the 'B. fragilis group' which suggests that B. fragilis does not play a significant role in acute appendicitis but may be a major cause of its septic complications.

journal_name

J Med Microbiol

authors

Elhag KM,Alwan MH,Al-Adnani MS,Sherif RA

doi

10.1099/00222615-21-3-245

subject

Has Abstract

pub_date

1986-05-01 00:00:00

pages

245-9

issue

3

eissn

0022-2615

issn

1473-5644

journal_volume

21

pub_type

杂志文章
  • Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cells.

    abstract::The fungal pathogen Cryptococcus neoformans has a predilection for the central nervous system (CNS), resulting in devastating meningoencephalitis. At present, it is unclear how C. neoformans traverses the blood-brain barrier (BBB) and causes CNS infection. The present study has examined and characterized the interacti...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.05230-0

    authors: Chen SHM,Stins MF,Huang SH,Chen YH,Kwon-Chung KJ,Chang Y,Kim KS,Suzuki K,Jong AY

    更新日期:2003-11-01 00:00:00

  • Evaluation of a recombinant antigen ELISA for the diagnosis of acute toxoplasmosis and comparison with traditional antigen ELISAs.

    abstract::An evaluation of five ELISA methods for the diagnosis of acute toxoplasmosis was undertaken by comparing a laboratory-produced ELISA employing two recombinant Toxoplasma gondii polypeptides as antigen with a laboratory-produced ELISA and three commercially available ELISAs employing traditional parasite antigen prepar...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-37-6-404

    authors: Johnson AM,Roberts H,Tenter AM

    更新日期:1992-12-01 00:00:00

  • Effects of sub-MIC concentrations of antibiotics on growth of and toxin production by Clostridium difficile.

    abstract::Effects on growth and toxin A production of sub-MIC concentrations of six different antibiotics were investigated in three strains of Clostridium difficile: reference strain NCTC 11223, a fully sequenced strain (630) and a locally endemic isolate (strain 338a). The antibiotics chosen for investigation were the agents ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.05387-0

    authors: Drummond LJ,Smith DGE,Poxton IR

    更新日期:2003-12-01 00:00:00

  • Application of terminal RFLP analysis to characterize oral bacterial flora in saliva of healthy subjects and patients with periodontitis.

    abstract::Terminal restriction fragment-length polymorphism (T-RFLP) analysis was applied to characterize oral bacterial flora in saliva from 18 healthy subjects and 18 patients with periodontitis. The 16S rRNA genes (rDNAs) of oral bacteria and spirochaetes in saliva were amplified by PCR with a 6'carboxy-fluorescein (6-FAM)-l...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.04991-0

    authors: Sakamoto M,Takeuchi Y,Umeda M,Ishikawa I,Benno Y

    更新日期:2003-01-01 00:00:00

  • A collaborative evaluation of a rapid, semi-automated identification system for gram-negative bacilli: the Quantum II BID.

    abstract::The recently-introduced semi-automated bacterial identification system, the Quantum II BID, is designed to identify fermentative and non-fermentative gram-negative bacilli in 4-5 h. The system was evaluated independently by the two participating laboratories. Inter-laboratory reproducibility was determined by testing ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-21-2-145

    authors: Stevens M,Henrichsen C,Smith M

    更新日期:1986-03-01 00:00:00

  • Molecular analysis and species diversity of Nocardia in the hospital environment in a developing country, a potential health hazard.

    abstract:PURPOSE:Despite hundreds of reports on the isolation of Nocardia from clinical samples, the presence and diversity of Nocardia species that are capable of survival in a harsh and adverse condition, such as a hospital environment, have not been comprehensively studied. The aim of this study was to assess Nocardia specie...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.000436

    authors: Rahdar HA,Azadi D,Shojaei H,Daei-Naser A

    更新日期:2017-03-01 00:00:00

  • Laboratory challenges in the diagnosis of hepatitis E virus.

    abstract::Hepatitis E virus (HEV) is an RNA virus that is an important cause of both acute and chronic hepatitis worldwide. To date, there are eight HEV genotypes that can infect mammals. HEV-1 and HEV-2 infect exclusively humans, while HEV-3 and HEV-4 infect humans and various animals, mainly pigs and deer. Additionally, two n...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.1099/jmm.0.000706

    authors: Al-Sadeq DW,Majdalawieh AF,Mesleh AG,Abdalla OM,Nasrallah GK

    更新日期:2018-04-01 00:00:00

  • Mechanism of persistent infection associated with peritoneal implants.

    abstract::The ability of rabbits to clear an intraperitoneal injection of Pseudomonas aeruginosa in the presence or absence of a surgically implanted peritoneal device was investigated. Sham-operated rabbits without an implant eliminated a P. aeruginosa challenge of 5 x 10(6) cfu/ml; lavage fluid and peritoneal tissues became c...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-36-6-406

    authors: Ward KH,Olson ME,Lam K,Costerton JW

    更新日期:1992-06-01 00:00:00

  • Engineering of an Iranian Bordetella pertussis strain producing inactive pertussis toxin.

    abstract::Introduction. Differences between the genomic and virulence profile of Bordetella pertussis circulating strains and vaccine strains are considered as one of the important reasons for the resurgence of whooping cough (pertussis) in the world. Genetically inactivated B. pertussis is one of the new strategies to generate...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.001114

    authors: Nikbin VS,Keramati M,Noofeli M,Tayebzadeh F,Kahali B,Shahcheraghi F

    更新日期:2020-01-01 00:00:00

  • Rapid molecular differentiation and genotypic heterogeneity among Candida parapsilosis and Candida orthopsilosis strains isolated from clinical specimens in Kuwait.

    abstract::Recent molecular studies have led to the recognition of three distinct species within the Candida parapsilosis complex, namely Candida parapsilosis, Candida orthopsilosis and Candida metapsilosis. As currently available yeast identification systems fail to differentiate these species, there is a paucity of information...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.008235-0

    authors: Asadzadeh M,Ahmad S,Al-Sweih N,Khan ZU

    更新日期:2009-06-01 00:00:00

  • Paradoxically high resistance of natural killer T (NKT) cell-deficient mice to Legionella pneumophila: another aspect of NKT cells for modulation of host responses.

    abstract::In the present study, we examined the roles of natural killer T (NKT) cells in host defence against Legionella pneumophila in a mouse model. The survival rate of NKT cell-deficient Jalpha281 knock-out (KO) mice was significantly higher than that of wild-type mice. There was no bacterial overgrowth in the lungs, but Ja...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.47747-0

    authors: Hayakawa K,Tateda K,Fuse ET,Matsumoto T,Akasaka Y,Ishii T,Nakayama T,Taniguchi M,Kaku M,Standiford TJ,Yamaguchi K

    更新日期:2008-11-01 00:00:00

  • Differential susceptibility of airway and ocular surface cell lines to FlhDC-mediated virulence factors PhlA and ShlA from Serratia marcescens.

    abstract::Introduction.Serratia marcescens is a bacterial pathogen that causes ventilator-associated pneumonia and ocular infections. The FlhD and FlhC proteins complex to form a heteromeric transcription factor whose regulon, in S. marcescens, regulates genes for the production of flagellum, phospholipase A and the cytolysin S...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.001292

    authors: Stella NA,Brothers KM,Shanks RMQ

    更新日期:2020-12-10 00:00:00

  • Experimental aerogenic Burkholderia mallei (glanders) infection in the BALB/c mouse.

    abstract::The object of this study was to develop and characterize experimental Burkholderia mallei aerosol infection in BALB/c mice. Sixty-five mice were infected with 5000 [approx. 2.5 median lethal doses (MLD)] B. mallei strain ATCC 23344(T) bacteria by the aerosol route. Bacterial counts within lung, liver, spleen, brain, k...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.05180-0

    authors: Lever MS,Nelson M,Ireland PI,Stagg AJ,Beedham RJ,Hall GA,Knight G,Titball RW

    更新日期:2003-12-01 00:00:00

  • Immunological characterisation of rubella virion polypeptides.

    abstract::Antibodies specific for rubella virion polypeptide, VPI, secreted by clones of hybridoma cells or produced in rabbits in response to specific antigenic stimulation, located determinants for haemagglutination inhibiting (HI) and neutralising (Nt) antibodies on this envelope component. ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-17-1-105

    authors: Ho-Terry L,Cohen A,Tedder RS

    更新日期:1984-02-01 00:00:00

  • Sensitivity of Pseudomonas aeruginosa to sulphonamides and trimethoprim and the activity of the combination trimethoprim: sulphamethoxazole.

    abstract::The activities of three sulphonamides and trimethoprim against strains of Pseudomonas aeruginosa have been studied. Sulphadiazine had most activity, sulphadimidine had little, and the activity of sulphamethoxazole was intermediate. According to their sensitivity to sulphamethoxazole, strains were divided into two grou...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-10-3-273

    authors: Grey D,Hamilton-Miller JM

    更新日期:1977-08-01 00:00:00

  • Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy.

    abstract::A novel combination of culturing and DNA-based terminal restriction fragment length polymorphism (TRFLP) analysis was used to investigate the effect of probiotics on antibiotic-induced gut microbiota alterations to determine if a probiotic preparation containing bifidobacteria and lactobacilli, taken during and after ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.47615-0

    authors: Engelbrektson A,Korzenik JR,Pittler A,Sanders ME,Klaenhammer TR,Leyer G,Kitts CL

    更新日期:2009-05-01 00:00:00

  • In vitro ceftaroline combinations against meticillin-resistant Staphylococcus aureus.

    abstract::We studied in vitro ceftaroline combinations against 61 meticillin-resistant Staphylococcus aureus isolates; 18 of them were also resistant to linezolid, using overlapping E-test method. Daptomycin-ceftaroline combination obtained lower fractional inhibitory concentration values, in comparison with those including van...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.000341

    authors: García AB,Candel FJ,López L,Chiarella F,Viñuela-Prieto JM

    更新日期:2016-10-01 00:00:00

  • Inhibition of quorum-sensing-controlled virulence factors of Pseudomonas aeruginosa by Murraya koenigii essential oil: a study in a Caenorhabditis elegans infectious model.

    abstract::The global emergence of antibiotic-resistant strains of Pseudomonas aeruginosa poses a major threat in both hospital environments and the community. P. aeruginosa is an opportunistic human pathogen, and it also infects a wide range of model organisms including the nematode Caenorhabditis elegans. Quorum sensing (QS) m...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.000385

    authors: Ganesh PS,Rai RV

    更新日期:2016-12-01 00:00:00

  • The effects of iclaprim on exotoxin production in methicillin-resistant and vancomycin-intermediate Staphylococcus aureus.

    abstract:PURPOSE:Extracellular protein toxins contribute to the pathogenesis of Staphylococcus aureus infections. The present study compared the effects of iclaprim and trimethoprim - two folic acid synthesis inhibitors - with nafcillin and vancomycin on production of Panton-Valentine leukocidin (PVL), alpha haemolysin (AH) and...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.000929

    authors: Bryant AE,Gomi S,Katahira E,Huang DB,Stevens DL

    更新日期:2019-03-01 00:00:00

  • Pleuritis due to Brevundimonas diminuta in a previously healthy man.

    abstract::Brevundimonas diminuta is rarely associated with invasive infections. We report the case of a previously healthy young man with pleural effusion, in which B. diminuta was recovered but incorrectly identified as Kingella kingae when it was freshly isolated. Consequently, the misidentification resulted in initial treatm...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.045013-0

    authors: Lu B,Shi Y,Zhu F,Xu X

    更新日期:2013-03-01 00:00:00

  • Effect of clearance of bacteria from the blood on the development of systemic bacteraemia in mice.

    abstract::Clearance of various bacteria isolated from portal and systemic blood of mice was evaluated and compared. All portal blood strains, including Escherichia coli and enterococci were eliminated more rapidly from the circulation than were strains isolated from systemic blood, including Pseudomonas aeruginosa. With mannose...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-38-5-337

    authors: Hirakata Y,Kaku M,Furuya N,Matsumoto T,Tateda K,Tomono K,Yamaguchi K

    更新日期:1993-05-01 00:00:00

  • Enhanced active efflux, repression of porin synthesis and development of Mar phenotype by diazepam in two enterobacteria strains.

    abstract::The aim of this work was to determine whether diazepam could induce the multiple antibiotic resistance (Mar) phenotype in Klebsiella pneumoniae and Escherichia coli strains. The Mar phenotype is characterized by decreased susceptibility to multiple antibiotics due to the loss of porins and/or increased expression of a...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.45613-0

    authors: Tavío MM,Vila J,Perilli M,Casañas LT,Maciá L,Amicosante G,Jiménez de Anta MT

    更新日期:2004-11-01 00:00:00

  • Drug response and genetic properties of Vibrio cholerae associated with endemic cholera in north-eastern Thailand, 2003-2011.

    abstract::Cholera, caused by Vibrio cholerae, results in significant morbidity and mortality worldwide, including Thailand. Representative V. cholerae strains associated with endemic cholera (n = 32), including strains (n = 3) from surface water sources, in Khon Kaen, Thailand (2003-2011), were subjected to microbiological, mol...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.053801-0

    authors: Chomvarin C,Johura FT,Mannan SB,Jumroenjit W,Kanoktippornchai B,Tangkanakul W,Tantisuwichwong N,Huttayananont S,Watanabe H,Hasan NA,Huq A,Cravioto A,Colwell RR,Alam M

    更新日期:2013-04-01 00:00:00

  • Exceptionally high titres in atypical presentation of occult epididymo-orchitis due to brucellosis.

    abstract::A male patient of 32 years was referred for surgical drainage and orchidectomy of the right testis following a cycling injury. A Venereal Disease Research Laboratory (VDRL) test was requested by the surgery department to rule out secondary syphilis. Although serum samples gave a negative result in the VDRL test, quali...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.034892-0

    authors: Purwar S,Metgud SC,Gokale SK

    更新日期:2012-03-01 00:00:00

  • In vitro activities of vancomycin and linezolid against biofilm-producing methicillin-resistant staphylococci species isolated from catheter-related bloodstream infections from an Egyptian tertiary hospital.

    abstract:PURPOSE:Catheter-related bloodstream infections (CRBSIs) are among the most common hospital-acquired infections. We aimed to survey methicillin resistance, biofilm production and susceptibility to vancomycin, linezolid and other antibiotics for staphylococci isolated from CRBSIs. METHODOLOGY:Fifty-eight isolates [20 S...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.000490

    authors: Hashem AA,Abd El Fadeal NM,Shehata AS

    更新日期:2017-06-01 00:00:00

  • Characterisation of the external surfaces of Pseudomonas aeruginosa isolated from human blood and respiratory tract.

    abstract::The surface structures of the cell envelopes of 16 clinical isolates of Pseudomonas aeruginosa were examined by electronmicroscopy with the new fixation technique of freeze-substitution. Two types of structures were observed among the organisms. In one group of strains, mostly isolated from blood, a dense fibrous laye...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-40-4-282

    authors: Misumi H,Umeda A,Eguchi K,Okada K,Sawae Y,Niho Y,Amako K

    更新日期:1994-04-01 00:00:00

  • Intra-individual diversity and similarity of salivary and faecal microbiota.

    abstract::In the present study, polyphasic analysis [cultivation, combined with the fingerprinting of individual isolates, and denaturing gradient gel electrophoresis (DGGE)] was applied to study whether similar features concerning the diversity and temporal stability of selected bacterial groups could be detected intra-individ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.47352-0

    authors: Maukonen J,Mättö J,Suihko ML,Saarela M

    更新日期:2008-12-01 00:00:00

  • The rectal mucosa-associated microflora in patients with ulcerative colitis.

    abstract::The rectal mucosa-associated flora (MAF) of patients with ulcerative colitis has been studied in 25 patients with newly diagnosed disease, 20 with relapse of existing disease, and 44 who were in remission. Patients with active disease were re-examined twice during treatment. The MAF was simpler and less dense than the...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-36-2-96

    authors: Hartley MG,Hudson MJ,Swarbrick ET,Hill MJ,Gent AE,Hellier MD,Grace RH

    更新日期:1992-02-01 00:00:00

  • Pyrolysis mass spectrometry in epidemiological and population genetic studies of Haemophilus influenzae.

    abstract::Haemophilus influenzae serotype b (Hib) vaccines have reduced the amount of invasive Hib disease in immunised infants. However, Hib disease remains in unvaccinated infants and adults and non-capsulate H. influenzae (NCHi) still causes infections, including outbreaks of respiratory disease. Characterisation of strains ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-46-3-204

    authors: Leaves NI,Sisson PR,Freeman R,Jordens JZ

    更新日期:1997-03-01 00:00:00

  • Zinc enhances the phototoxic effect of blue light against malodour-producing bacteria in an experimental oral biofilm.

    abstract::Oral malodour is thought to be caused mainly by the production of volatile sulfide compounds (VSCs) by anaerobic Gram-negative oral bacteria. Previous studies have shown that these bacteria are susceptible to blue light (400-500 nm wavelength). In the present study, we tested the effect of blue light in the presence o...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.075044-0

    authors: Sterer N,Jeffet U,Dadoun A,Greenstein RB,Kohavi D

    更新日期:2014-08-01 00:00:00