Effect of chronic chloroquine treatment on prostaglandin and human chorionic gonadotropin (hCG) stimulation of testosterone secretion by the rat testis.

abstract：:Corpus cavernosum smooth muscle cells (CCSMCs) are important functional cells for penile erection. We evaluated the effect of transforming growth factor β1 (TGFβ1) and hepatocyte growth factor (HGF) on the viability and apoptosis of CCSMCs in vitro. CCSMCs from healthy male Sprague Dawley rats were randomly divided in...

journal_title：Andrologia

authors： Liu T,Peng YF,Jia C,Yang BH,Tao X,Fang X,Zhong W

更新日期：2015-11-01 00:00:00

abstract：:In a prospective study, the polymorphism of oestrogen receptor β gene was investigated in nonobstructive azoospermia patients. Ninety infertile patients with nonobstructive azoospermia diagnosed after two semen analysis, 2 weeks apart and negative testicular sperm extraction during intracytoplasmic sperm injection, an...

journal_title：Andrologia

authors： Younes AH,Hamed HB,Mohamed EM,Makki MA,Gaber N,Mohamed HM

更新日期：2016-12-01 00:00:00

abstract：:Leydig cell function, as judged from testosterone concentrations in plasma and in testicular tissue after LH stimulation, was tested in adult rat testes 4 days after brief exposure of the scrotum to 33 degrees and 43 degrees C, respectively. There was no significant difference in basal plasma testosterone concentratio...

journal_title：Andrologia

authors： Damber JE,Bergh A,Janson PO

更新日期：1980-01-01 00:00:00

abstract：:Azoospermia factor (AZF) genes on the long arm of the human Y chromosome are involved in spermatogenesis, and microdeletions in the AZF region have been recognised to be the second major genetic cause of spermatogenetic failure resulting in male infertility. While screening for these microdeletions can avoid unnecessa...

journal_title：Andrologia

authors： Zhu XB,Gong YH,He J,Guo AL,Zhi EL,Yao JE,Zhu BS,Zhang AJ,Li Z

更新日期：2017-06-01 00:00:00

abstract：:Searching for further characteristics of sperm in the diagnosis of male infertility it was examined if ejaculates with "normo-, oligo-, astheno-, terato-" and "azoospermia" showed typical modifications in their triglyceride- and phospholipid contents. The examination was conveyed in spermatozoa and seminal plasma. In ...

journal_title：Andrologia

authors： Kulka P,Nissen HP,Kreysel HW

更新日期：1984-01-01 00:00:00

abstract：:Several drugs have been used to stimulate human sperm motility, including 3-deoxy-adenosine, caffeine, and pentoxifylline. Pentoxifylline is an inhibitor of the phosphodiesterase and may stimulate sperm motility by increasing the intracellular levels of cAMP. In this study we have evaluated the effect of pentoxifyllin...

journal_title：Andrologia

authors： Morales P,Llanos M,Yovich JL,Cummins JM,Vigil P

更新日期：1993-11-01 00:00:00

abstract：:This investigation was carried out to study the correlation of sperm quality parameters with antioxidant and oxidant status of buffalo bull semen during various stages of cryopreservation. Semen samples were evaluated for sperm parameters (mass motility [MM], concentration [CON], progressive motility [PM], viability [...

journal_title：Andrologia

authors： Lone SA,Prasad JK,Ghosh SK,Das GK,Balamurugan B,Verma MR

更新日期：2018-02-11 00:00:00

abstract：:Sperm investigations of 35 epileptics being treated with hydantoin for a period of more than three years have shown that by a large dispersion of evaluations only 52% of the sperm cells were intact (teratozoospermia; compared with a normal limit of 60% p = 5%, of 70% p = 1%). The mobility of the sperm cells was 49% (a...

journal_title：Andrologia

authors： Schramm P,Seyfeddinipur N

更新日期：1980-01-01 00:00:00

abstract：:Subnormal levels of testosterone are associated with significant negative health consequences, with higher risks of all-cause and cardiovascular mortality. The numbers of studies reporting on the benefits of normalisation of testosterone is increasing but longer-term data on (elderly) men receiving testosterone treatm...

journal_title：Andrologia

authors： Yassin AA,Nettleship J,Almehmadi Y,Salman M,Saad F

更新日期：2016-09-01 00:00:00

abstract：:Elevated platelet levels have been postulated to be associated with cardiovascular diseases, conditions closely linked to erectile dysfunction (ED). The current systematic review and meta-analysis was performed to assess the platelet indices, which including platelet count (PLT), mean platelet volume (MPV) and platele...

journal_title：Andrologia

authors： Yang G,Muzepper M

更新日期：2019-06-01 00:00:00

abstract：:The levels of eight enzymes have been measured in the semen of 15 azoospermic subjects. The results indicate that the values of the enzymes Creatine kinase, and Alanine aminotransferase, just as the Aspartate aminotransferase/Alanine aminotransferase ratio are significantly different between excretory and secretory az...

journal_title：Andrologia

authors： Gonzalez Buitrago JM,Garcia Diez LC

更新日期：1982-01-01 00:00:00

abstract：:The objective of this study was to evaluate pubertal onset and characteristics in Egyptian boys. Examination of schoolboys (9-18 years) included height (cm), penile length (cm) and testicular volume (ml). Pubertal onset was considered at gonadal (G) stage 2 (G2 indicated testicular volume from 4-8 ml). Out of 1,078 bo...

journal_title：Andrologia

authors： Saleh R,Abu El-Hamd M,Abdel-Karim M,Abdelrahman H

更新日期：2019-03-01 00:00:00

abstract：:Between 1994 and 2010, a total of 123 patients with obstructive azoospermia due to aplasia of vas deferens (CAVD) were surgically treated. In 110 patients, the condition was bilateral (CBAVD), 13 men had unilateral aplasia (CUAVD), and 10 patients additionally had aplasia of one kidney. All patients underwent CFTR gen...

journal_title：Andrologia

authors： Schwarzer JU,Schwarz M

更新日期：2012-10-01 00:00:00

abstract：:The pre-operative treatment of three adult male transsexuals with the anti-androgen and progestogenic compound cyproterone acetate is reported. When used in combination with cyproterone acetate, only a very small dose of oestrogen is needed to induce feminisation. The effect of this treatment on both testicular and ep...

journal_title：Andrologia

authors： Jequier AM,Bullimore NJ,Bishop MJ

更新日期：1989-09-01 00:00:00

abstract：:The acrosome reaction of human spermatozoa was induced by changes of temperature. Spermatozoa were collected from fertile donors and a patient group, and selected by the "swim-up" method. The spermatozoa were treated in two different ways: Protocol I: 24 hours at room temperature followed by additional incubation at 3...

journal_title：Andrologia

authors： Sanchez R,Toepfer-Petersen E,Aitken RJ,Schill WB

更新日期：1991-05-01 00:00:00

abstract：:Insulin-like factor 3 (INSL3) has an important role in the human reproductive system; however, its detailed function is still mysterious. We aimed to investigate the possibility of expression of RXFP2 receptor on human spermatozoa and to determine the anti-apoptotic and antioxidant mechanism derived the binding of INS...

journal_title：Andrologia

authors： Shokri S,Tavalaee M,Ebrahimi SM,Ziaeipour S,Nasr-Esfahani MH,Nejatbakhsh R

更新日期：2020-10-01 00:00:00

abstract：:In order to elucidate the ultrastructural characteristics of the precursor cell of Leydig cells and its subsequent differentiation, testicular biopsies from two patients with hypogonadotropic hypogonadism, obtained prior to and after treatment with HCG and HMG, were studied in comparison with those of prepubertal, pub...

journal_title：Andrologia

authors： Nistal M,Paniagua R

更新日期：1979-05-01 00:00:00

abstract：:Carnitine represents the secretion which is added to human seminal fluid by the epididymis. More than 94% of the free carnitine originates from the epididymis. The frequency distribution of carnitine concentration is investigated with patients showing a normal spermiogram and with those suffering from azoospermia. Cor...

journal_title：Andrologia

authors： Wetterauer U,Heite HJ

更新日期：1978-05-01 00:00:00

abstract：:The events occurring at the maternal-foetal interface define a successful pregnancy but the current paradigm has shifted towards assessing the contribution of spermatozoa for embryogenesis. Spermatozoa with defective DNA integrity may fertilise the oocyte but affect subsequent embryonic development. The present case-c...

journal_title：Andrologia

authors： Dhawan V,Kumar M,Deka D,Malhotra N,Singh N,Dadhwal V,Dada R

更新日期：2019-02-01 00:00:00

abstract：:This short review summarizes some recent findings on arylhydrocarbon (dioxin) receptor expression during early pregnancy in mammals. The arylhydrocarbon receptor is a ligand-activated transcription factor and was originally described as a mediator of the toxic effects of dioxins and other chlorinated hydrocarbons such...

journal_title：Andrologia

authors： Fischer B

更新日期：2000-09-01 00:00:00

abstract：:Two groups of 5 rabbits were actively immunized with porcine relaxin or sham immunized. Serial analysis of sperm motion characteristics using the computer assisted Hamilton-Thorn Motility Analyzer over a period of 22 weeks did not reveal any significant antibody titers in serum and seminal plasma. In consideration of ...

journal_title：Andrologia

authors： Jockenhövel F,Altensell A,Nieschlag E

更新日期：1990-03-01 00:00:00

abstract：:The aim of this study was to analyse the effect of pirfenidone against ischaemia-reperfusion injury occurring after detorsion in rats with induced testicular torsion model. Group 1 was assigned as the control group. Group 2 first had testis torsion performed, and then, testicular detorsion was performed. Group 3 had s...

journal_title：Andrologia

authors： Kölükçü E,Firat F,Deresoy FA,Katar M,Atılgan D

更新日期：2020-11-26 00:00:00

abstract：:Previous studies have shown that alpha1-adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This study was designed to investigate the effects of terazosin on the catalase expression in the seminal vesicles and the lipid peroxidation of the seminal fluid in normal...

journal_title：Andrologia

authors： Mitropoulos D,Patris E,Deliconstantinos G,Kyroudi-Voulgari A,Anastasiou I,Perea D

更新日期：2013-04-01 00:00:00

abstract：:The objective was to determine effects of gallic acid (GA) and carnosic acid (CA), present in carob pods and rosemary extract respectively, on frozen-thawed ram spermatozoa. Thirty ejaculates were collected from five Merino rams, pooled, diluted in Tris-based extender and divided into five equal portions containing: 0...

journal_title：Andrologia

authors： Gungor S,Inanc ME,Ozturk C,Korkmaz F,Bastan I,Cil B,Kastelic JP

更新日期：2019-11-01 00:00:00

abstract：:In cases of azoospermia especially after vasectomy the investigation of the seminal sediment investigation is necessary. Exclusive on this way it is possible to find some side dispersed spermatozoa. The described case deals with a pregnancy about 48 days following vasectomy. Postoperative the sperm sediment investigat...

journal_title：Andrologia

authors： Schirren C

更新日期：1984-07-01 00:00:00

abstract：:In a controlled double blind trial the effectiveness and tolerability of Kallikrein in patients suffering from astheno-oligozoospermia was examined in comparison to placebo. 30 patients with astheno-oligozoospermia of idiopathic origin entered the study; they were subdivided into two homogeneous groups of 15 patients ...

journal_title：Andrologia

authors： Izzo PL,Canale D,Bianchi B,Meschini P,Esposito G,Menchini Fabris GF,Fasani R,Ohnmeiss H

更新日期：1984-03-01 00:00:00

abstract：:When washed human sperm were incubated in a modified Krebs-Ringer buffer solution in the absence of exogenous metabolizable substrates at 30 degrees C they maintained progressive motility for at least six hours. Under these conditions the spermatozoa apparently utilize endogenous substrates but addition of exogenous s...

journal_title：Andrologia

authors： Shalev DP,Soffer Y,Lewin LM

更新日期：1986-07-01 00:00:00

abstract：:Two monoclonal antibodies (MAbs) directed against human protamine P1 were realized. Anti-P1 specificity was assessed by western-blot and confirmed by ELISA. Monoclonal antibody 97-3 was selected. Protamine P1 was specifically demonstrated in human testis by immunoelectron microscopy, using 97-3 MAb and an indirect pos...

journal_title：Andrologia

authors： Lescoat D,Blanchard Y,Lavault MT,Quernée D,Le Lannou D

更新日期：1993-03-01 00:00:00

abstract：:Leydig cell tumours (LCTs) of the testis are rare. Their origin is still unknown. This case report describes a potential relationship between LCT and prolonged exposure to Finasteride. ...

journal_title：Andrologia

authors： Berthold D,Lhermitte B,Uffer M,Doerfler A

更新日期：2012-05-01 00:00:00

abstract：:There is growing concern that abnormalities in male reproductive health are becoming more frequent. The most fundamental change has been the striking decline in sperm counts and semen quality. The effect of maternal exposure of rats to the oestrogenic environmental substance p-nonylphenol (p-NP) was determined in this...

journal_title：Andrologia

authors： de Jager C,Bornman MS,Oosthuizen JM

更新日期：1999-03-01 00:00:00