Abstract:
:The ade6-M26 mutation of Schizosaccharomyces pombe has previously been reported to stimulate ade6 intragenic meiotic recombination. We report here that the ade6-M26 mutation is a single G----T nucleotide change, that M26 stimulated recombination within ade6 but not at other distinct loci, and that M26 stimulated meiotic but not mitotic recombination. In addition, M26 stimulated recombination within ade6 when M26 is homozygous; this result demonstrates that a base-pair mismatch at the M26 site was not required for the stimulation. These results are consistent with the ade6-M26 mutation creating a meiotic recombination initiation site.
journal_name
Geneticsjournal_title
Geneticsauthors
Ponticelli AS,Sena EP,Smith GRsubject
Has Abstractpub_date
1988-07-01 00:00:00pages
491-7issue
3eissn
0016-6731issn
1943-2631journal_volume
119pub_type
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