Abstract:
:DNAs from fourteen fibrosarcomas induced by 3-methylcholanthrene (MCA) in BALB/c mice were analyzed for the presence of transforming oncogenes following transfection on NIH3T3 cells. Six transfection-positive DNAs contained an activated ras gene: four c-K-ras and two c-N-ras. These results demonstrate that c-K-ras is not the only oncogene of the ras family activated in MCA-induced murine fibrosarcomas as was previously indicated.
journal_name
Carcinogenesisjournal_title
Carcinogenesisauthors
Borrello MG,Carbone G,Pierotti MA,Molla A,Della Porta Gdoi
10.1093/carcin/9.8.1517subject
Has Abstractpub_date
1988-08-01 00:00:00pages
1517-9issue
8eissn
0143-3334issn
1460-2180journal_volume
9pub_type
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