Abstract:
:Previous research implicates an endogenous central pain inhibitory mechanism in opiate analgesia, analgesia produced by focal electrical stimulation of the brain, and acupuncture analgesia. This investigation evaluates the possibility that analgesia produced by hypnosis is also mediated by such a mechanism. Results suggest that hypnotic analgesia is unlikely to involve this central pain inhibitory mechanism since hypnotic analgesia is not altered by naloxone hydrochloride, a specific narcotic antagonist. Results further demonstrate that the hypnotic procedure used produces an unusually effective and reliable increase in pain threshold. This finding generalizes to the control of clinical dental pain, and suggests that hypnotic pain control is a more widespread phenomenon in the population than has been thought.
journal_name
Painjournal_title
Painauthors
Barber J,Mayer Ddoi
10.1016/0304-3959(77)90085-9subject
Has Abstractpub_date
1977-10-01 00:00:00pages
41-48issue
1eissn
0304-3959issn
1872-6623pii
00006396-197710001-00003journal_volume
4pub_type
临床试验,杂志文章相关文献
PAIN文献大全abstract::In recent years, oxytocin has been implicated in a wide diversity of functions. The role of oxytocin in analgesia and pain modulation represents an important new function of an endogenous system controlling sensorial information. The paraventricular (PV) nucleus of the hypothalamus is one of the most important sources...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2006.01.029
更新日期:2006-05-01 00:00:00
abstract::Extraterritorial spread of sensory symptoms is frequent in carpal tunnel syndrome (CTS). Animal models suggest that this phenomenon may depend on central sensitization. We sought to obtain psychophysical evidence of sensitization in CTS with extraterritorial symptoms spread. We recruited 100 unilateral CTS patients. A...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2009.10.025
更新日期:2010-02-01 00:00:00
abstract::The perception of pain is determined by a combination of genetic, neurobiological, cultural, and emotional factors. Recent studies have demonstrated an association between specific genotypes and pain perception. Particular focus has been given to the triallelic polymorphism in the promoter region of the serotonin tran...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2013.05.011
更新日期:2013-08-01 00:00:00
abstract::The experiments determined the ventilatory effects of epidurally injected morphine and sufentanil in rats in the absence and in the presence of chlordiazepoxide, a drug that may alleviate the effects of stress. Soon after administration of morphine as well as of sufentanil, ventilation was more profoundly depressed wh...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(89)90159-0
更新日期:1989-04-01 00:00:00
abstract::Neuropathic pain may be produced, at least in part, by the increased activity of primary afferent neurons. Studies have suggested that an accumulation of voltage-gated sodium channels at the site of peripheral nerve injury is a primary precursory event for subsequent afferent hyperexcitability. In this study, a human ...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/S0304-3959(98)00120-1
更新日期:1998-11-01 00:00:00
abstract::Acute microinjection of mu-, delta-, or kappa-opioid receptor (MOPr, DOPr, KOPr) agonists into the rostral ventromedial medulla (RVM) produces antinociception. Thermal antinociception produced by MOPr and DOPr agonists is potentiated during inflammation [Hurley RW, Hammond DL. The analgesic effects of supraspinal mu a...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2007.07.010
更新日期:2008-06-01 00:00:00
abstract::microRNAs (miRNAs) are small noncoding RNAs that have been linked to a number of disease-related signal transduction pathways. Several studies indicate that they are also involved in nociception. It is not clear, however, which miRNAs are important and which genes are modulated by miRNA-associated mechanisms. This stu...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2012.11.010
更新日期:2013-03-01 00:00:00
abstract::Postherpetic neuralgia (PHN) is a debilitating chronic pain condition, yet there is a lack of knowledge regarding underlying brain activity. Here we identify brain regions involved in spontaneous pain of PHN (n=11) and determine its modulation with Lidoderm therapy (patches of 5% lidocaine applied to the PHN affected ...
journal_title:Pain
pub_type: 临床试验,杂志文章
doi:10.1016/j.pain.2006.09.014
更新日期:2007-03-01 00:00:00
abstract::The neurochemical effects of adenosine signaling in small-fiber neuropathy leading to neuropathic pain are yet to be explored in a direct manner. This study examined this system at the level of ligand (through the ectonucleotidase activity of prostatic acid phosphatase [PAP]) and adenosine A1 receptors (A1Rs) in resin...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001246
更新日期:2018-08-01 00:00:00
abstract::This paper presents the results of a detailed study of the pain epidemiology and health related quality of life (HRQL) in 150 chronic non-malignant pain patients consecutively referred to a Danish multidisciplinary pain center. Mean pain severity was 71.6 (SD = 18.5) on the VAS scale. Forty-two percent reported poor q...
journal_title:Pain
pub_type: 临床试验,杂志文章
doi:10.1016/S0304-3959(97)00126-7
更新日期:1997-12-01 00:00:00
abstract::Biopsychosocial models of chronic pain that recognize psychological and environmental factors as important aspects of adjustment to pain have been proposed for understanding chronic pain and related suffering in persons with multiple sclerosis (MS), but such models have not been empirically tested. The objective of th...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2006.07.017
更新日期:2007-01-01 00:00:00
abstract::Patients with chronic low back pain (LBP) frequently demonstrate high scores for fear-avoidance beliefs and distress. We need better knowledge about fear-avoidance beliefs and distress in early stages of LBP. The objectives of this study were to compare the level of fear-avoidance beliefs and distress in patients with...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2004.09.020
更新日期:2004-12-01 00:00:00
abstract::The characteristics and impact of pain were evaluated in a prospective cross-sectional survey of 438 ambulatory AIDS patients recruited from health care facilities in New York City. More than 60% of the patients reported 'frequent or persistent pain' during the 2 wks preceding the study. Patients with pain reported an...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/s0304-3959(96)03215-0
更新日期:1996-12-01 00:00:00
abstract::Tolerance to the antinociceptive (analgesic) effect of morphine, a mu-opioid agonist, was developed in male CD-1 mice as assessed by a shift to the right of the analgesic (tail-flick) dose-response curves and an increase in the ED50 values. Administration of dextromethorphan at 30 mg/kg s.c., but not saline, 30 min pr...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(94)90022-1
更新日期:1994-12-01 00:00:00
abstract::This study determined whether opiates alter vascular components of inflammation (hyperthermia, edema and plasma extravasation) in addition to the suppression of hyperalgesia. Rats were administered carrageenan into one hind paw and saline into the other hind paw, followed by i.p. injection of morphine (0.2-5.0 mg/kg) ...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(90)90054-H
更新日期:1990-10-01 00:00:00
abstract::To estimate the prevalence of orofacial pain (OFP) by specific diagnostic subgroups in the general population. Cross-sectional population study. General medical practice in South East Cheshire, UK. Participants of baseline investigation who completed the full postal questionnaire (1510, adjusted study participation ra...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2004.07.002
更新日期:2004-10-01 00:00:00
abstract::Cognitive factors are thought to play an important mediational role between pain and consequent levels of suffering, yet there has been little investigation of these issues in older chronic pain patients. The present study sought to examine the reliability and validity of the Pain Locus of Control (PLOC) scale when us...
journal_title:Pain
pub_type: 临床试验,杂志文章
doi:10.1016/S0304-3959(99)00284-5
更新日期:2000-04-01 00:00:00
abstract::Medical case management has improved in the past few decades, changing the dynamic interaction between depression and prevalent medical diseases. It is relevant to describe the comorbidity between depression and medical diseases to further improve the effectiveness of case management. We analyzed the data of adults ag...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000000826
更新日期:2017-04-01 00:00:00
abstract::Electron microscopy was used to study normal human extracted teeth in order to define the junctions between sensory nerve endings and other cells in external pulp and inner dentin at the crown tip. Two sets of associated cells were found: (1) Connective tissue cells. The pulpal fibroblast newtork made occasional desmo...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(82)90012-4
更新日期:1982-07-01 00:00:00
abstract::Sensitization of purinergic P2X3 receptors (P2X3Rs) is a major mechanism contributing to injury-induced exaggerated pain responses. We showed in a previous study that cyclic adenosine monophosphate (cAMP)-dependent guanine nucleotide exchange factor 1 (Epac1) in rat sensory dorsal root ganglia (DRGs) is upregulated af...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000000547
更新日期:2016-07-01 00:00:00
abstract::Primary burning mouth syndrome (BMS) is defined as an "intraoral burning or dysaesthetic sensation, recurring daily… more than 3 months, without clinically evident causative lesions" (IHS 2013). In addition to pain, taste alterations are frequent (dysgeusia, xerostomia). Although lacking clinical signs of neuropathy, ...
journal_title:Pain
pub_type: 杂志文章,评审
doi:10.1097/j.pain.0000000000001090
更新日期:2018-03-01 00:00:00
abstract::In rats anaesthetised with Saffan (Glaxovet), inhibition of the tail flick reflex evoked by electrical stimulation in the dorsal periaqueductal grey matter (PAG) was accompanied by an increase in blood pressure, tachycardia, vasodilatation in hind limb muscle, an increase in respiration, pupillodilatation and widening...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(85)90088-0
更新日期:1985-03-01 00:00:00
abstract::Chronic pain is currently considered a public health problem with high costs to the individual and society. To improve prevention and treatment of chronic pain, epidemiologic studies are mandatory for assessing chronic pain. The aims of this study were to estimate the prevalence of chronic pain in the adult Danish pop...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2012.07.023
更新日期:2012-12-01 00:00:00
abstract::In inflammatory neuropathy, immune activation near intact peripheral nerves induces mechanical allodynia. The identity of the peripheral immune product(s) that lead to these changes in pain behavior is unknown. The present series of studies utilized the sciatic inflammatory neuropathy (SIN) model to examine this quest...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2004.04.008
更新日期:2004-07-01 00:00:00
abstract::A preliminary report of clinical study revealed that chronic discogenic low back pain could be treated by intradiscal methylene blue (MB) injection. We investigated the effect of intradiscal MB injection for the treatment of chronic discogenic low back pain in a randomized placebo-controlled trial. We recruited 136 pa...
journal_title:Pain
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.pain.2010.01.021
更新日期:2010-04-01 00:00:00
abstract::The aim of this study was to test the capacity of the Fear Avoidance Model to explain the relationship between pain and disability in patients with whiplash-associated disorders. Using the method of Baron and Kenny, we assessed the mediating effect of fear of movement on the cross-sectional and longitudinal relationsh...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2011.09.023
更新日期:2012-01-01 00:00:00
abstract::The role of 5-hydroxytryptamine (5-HT)(4), 5-HT(6), and 5-HT(7) receptors in formalin-induced secondary allodynia and hyperalgesia in rats was assessed. Formalin produced acute nociceptive behaviors (flinching and licking/lifting) followed by long-term secondary mechanical allodynia and hyperalgesia. Pretreatment (-10...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2010.12.020
更新日期:2011-03-01 00:00:00
abstract::We evaluated the construct validity (including responsiveness), reliability, and feasibility of the Pain Squad multidimensional smartphone-based pain assessment application (app) in children and adolescents with cancer, using 2 descriptive studies with repeated measures. Participants (8-18 years) undergoing cancer tre...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000000385
更新日期:2015-12-01 00:00:00
abstract::The social determinants of health (SDH) are known to differentially impact outcomes from many noncommunicable diseases; however, their potential role in low back pain (LBP) is poorly defined. This review endeavours to comprehensively inform the field of their relevance. Our research question was: "How do the broad ran...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001944
更新日期:2020-11-01 00:00:00
abstract::Intense stress and fear have long been known to give rise to a suppression of pain termed "stress-induced analgesia", mediated by brainstem pain-modulating circuitry, including pain-inhibiting neurons of the rostral ventromedial medulla. However, stress does not invariably suppress pain, and indeed, may exacerbate it....
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2009.01.011
更新日期:2009-04-01 00:00:00