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Flordipine, a calcium channel blocker, which does not influence lipidemia or atherosclerosis in cholesterol-fed rabbits.

Abstract：

:Data relating to the effects of calcium channel blockers on experimental atherosclerosis in rabbits are inconsistent with most studies finding no effect on either serum lipids or atherosclerosis. We have administered flordipine (5, 15 or 45 mg/kg/day) for 10 weeks to rabbits fed 1% cholesterol and 4% corn oil. At no level of treatment was there an effect on serum or liver lipids or on aortic sudanophilia.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Kritchevsky D,Tepper SA,Klurfeld DM

doi

10.1016/0021-9150(88)90292-4

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

89-92

issue

1

eissn

0021-9150

issn

1879-1484

pii

0021-9150(88)90292-4

journal_volume

69

pub_type

杂志文章

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