当前位置： SCI文献检索 > ATHEROSCLEROSIS期刊下所有文献 > Analysis of the T cell receptor V beta repertoire in human aortic aneurysms.

Analysis of the T cell receptor V beta repertoire in human aortic aneurysms.

Abstract：

:Human aortic aneurysm is commonly characterized by the presence of advanced atherosclerosis associated with variable chronic adventitial inflammation. Histological examination of human aortic aneurysmal specimens revealed the presence of plasma cells and lymphoid aggregates in media and adventitia of the vessels. Immunostaining further demonstrated that CD3-positive T lymphocytes are present in follicles. Using a highly sensitive reverse transcription-polymerase chain reaction amplification method, the T cell receptor (TCR) V beta gene expression in aortic aneurysms was shown to be polyclonal. Furthermore. there was no preferential expression of any TCR V beta gene in the aortic tissue as compared with that in peripheral blood in aneurysmal patients. These results indicate that the TCR repertoire in aortic aneurysm is not restricted.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Yen HC,Lee FY,Chau LY

doi

10.1016/s0021-9150(97)00138-x

subject

Has Abstract

pub_date

1997-11-01 00:00:00

pages

29-36

issue

1

eissn

0021-9150

issn

1879-1484

pii

S0021-9150(97)00138-X

journal_volume

135

pub_type

杂志文章

相关文献

ATHEROSCLEROSIS文献大全
  • LncRNA HOXA-AS2 represses endothelium inflammation by regulating the activity of NF-κB signaling.

    abstract：BACKGROUND AND AIMS:Endothelium inflammation, which can lead to endothelial activation and dysfunction, is widely accepted as the major event in multiple vascular disorders. The lncRNA HOXA-AS2 was previously reported to be involved in multiple inflammation-linked cancers. However, the role of HOXA-AS2 in endothelium i...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2018.12.012

    authors： Zhu X,Liu Y,Yu J,Du J,Guo R,Feng Y,Zhong G,Jiang Y,Lin J

    更新日期：2019-02-01 00:00:00

  • Effect of bezafibrate during 4.5 years of treatment of hyperlipoproteinaemia.

    abstract：:Bezafibrate in a dosage of 200 mg 3 times daily was given to 24 patients with type II A (n = 8), II B (n = 1) and IV (n = 15) hyperlipoproteinaemia for 4.5 years. In type II A the content of total cholesterol and that of low density lipoprotein in serum decreased by 10-23 and 11-34 percent over the years compared to p...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(85)90098-x

    authors： Olsson AG,Lang PD,Vollmar J

    更新日期：1985-05-01 00:00:00

  • Effect of chronic renal failure and methylprednisolone treatment on the uptake of labelled plasma cholesterol into the aorta of normocholesterolemic rabbits.

    abstract：:The effects of chronic renal failure (CRF) and corticosteroid treatment on the aortic uptake of labelled free and esterified cholesterol (FC and EC) were investigated in normocholesterolemic rabbits. Methylprednisolone, 0.4 mg/day, or placebo was administered for 14 weeks to rabbits with normal renal function and with...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(83)90155-7

    authors： Tvedegaard E,Szpirt W,Nielsen M

    更新日期：1983-05-01 00:00:00

  • Postprandial regulation of blood lipids and adipose tissue lipoprotein lipase in type 2 diabetes patients and healthy control subjects.

    abstract：BACKGROUND/AIM:In type 2 diabetes and other insulin-resistant conditions, postprandial hypertriglyceridaemia is an important metabolic perturbation. To further elucidate alterations in the clearance of triglyceride-rich lipoproteins in type 2 diabetes we focused on the nutritional regulation of adipose tissue lipoprote...

    journal_title：Atherosclerosis

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0021-9150(02)00366-0

    authors： Eriksson JW,Burén J,Svensson M,Olivecrona T,Olivecrona G

    更新日期：2003-02-01 00:00:00

  • Smoking is associated with lower amounts of arterial type I collagen and decorin.

    abstract：BACKGROUND:Smoking affects the arterial wall and increases the risk of cardiovascular disease. It also affects the extracellular matrix in skin, causing impaired wound healing. However, little is known about putative molecular changes in the arterial wall. Our aim was to investigate the possible correlation between ext...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2016.02.022

    authors： Faarvang AS,Rørdam Preil SA,Nielsen PS,Beck HC,Kristensen LP,Rasmussen LM

    更新日期：2016-04-01 00:00:00

  • Hypolipidemic effects in dogs of ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

    abstract：:ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase, significantly reduced both serum cholesterol and phospholipid levels in dogs, when used at a dosage higher than 10 mg/kg per day. Triglyceride levels were not consistently changed, but beta- and pre-beta-lipoproteins were preferentially redu...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(79)90174-6

    authors： Tsujita Y,Kuroda M,Tanzawa K,Kitano N,Endo A

    更新日期：1979-03-01 00:00:00

  • Global vasomotor dysfunction and accelerated vascular aging in beta-thalassemia major.

    abstract：BACKGROUND:Patients with beta-thalassemia major (beta-TM) demonstrate an increased incidence of vascular complications, which are thought to result from a procoagulant/proinflammatory environment. We investigated the arterial vasorelaxing capacity and sought for early carotid atherosclerosis and underlying pathophysiol...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2007.09.030

    authors： Hahalis G,Kremastinos DT,Terzis G,Kalogeropoulos AP,Chrysanthopoulou A,Karakantza M,Kourakli A,Adamopoulos S,Tselepis AD,Grapsas N,Siablis D,Zoumbos NC,Alexopoulos D

    更新日期：2008-06-01 00:00:00

  • Different expression of modified low density lipoprotein receptors in rabbit peritoneal macrophages and Kupffer cells.

    abstract：:We have previously reported that mouse peritoneal macrophages have three types of modified low density lipoprotein (LDL) receptors. One is specific for acetylated LDL (Ac-LDL), the second is for oxidized LDL (Ox-LDL), and the third recognizes both (Arai, H. et al. (1989) Biochem. Biophys. Res. Commun. 159, 1375-1382)....

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(93)90098-f

    authors： Ueda Y,Arai H,Kawashima A,Nagano Y,Cho M,Tanaka M,Kita T

    更新日期：1993-06-01 00:00:00

  • Aortic response to relaxing agents in Watanabe heritable hyperlipidemic (WHHL) rabbits of different age.

    abstract：:Serum and aortic tissue cholesterol levels in parallel with aortic relaxation to endothelium-dependent and independent drugs were determined in Watanabe heritable hyperlipidemic (WHHL) rabbits in comparison with New Zealand (N.Z.) normocholesterolemic rabbits, aged 4-14 months. Serum cholesterol was elevated (626 +/- ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(91)90063-9

    authors： Chinellato A,Banchieri N,Pandolfo L,Ragazzi E,Froldi G,Norido F,Caparrotta L,Fassina G

    更新日期：1991-08-01 00:00:00

  • Effects of dietary saturated, monounsaturated and n-3 fatty acids on fasting lipoproteins, LDL size and post-prandial lipid metabolism in healthy subjects.

    abstract：BACKGROUND:The influence of the quality of dietary fat on some aspects of lipid metabolism-i.e. lipoprotein concentrations, post-prandial lipids and LDL size-is not completely understood, especially in healthy individuals. OBJECTIVES:Aim of this study was to evaluate the effects of different types of dietary fat (mono...

    journal_title：Atherosclerosis

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0021-9150(02)00424-0

    authors： Rivellese AA,Maffettone A,Vessby B,Uusitupa M,Hermansen K,Berglund L,Louheranta A,Meyer BJ,Riccardi G

    更新日期：2003-03-01 00:00:00

  • A point mutation in ABC1 gene in a patient with severe premature coronary heart disease and mild clinical phenotype of Tangier disease.

    abstract：:The proband is a 50 year-old woman born from a consanguineous marriage. She has been suffering from angina pectoris since the age of 38 and underwent coronary bypass surgery for three-vessel disease at 48. The presence of low plasma levels of total cholesterol and high density lipoprotein (HDL) cholesterol (2.4 and 0....

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(00)00587-6

    authors： Bertolini S,Pisciotta L,Seri M,Cusano R,Cantafora A,Calabresi L,Franceschini G,Ravazzolo R,Calandra S

    更新日期：2001-02-15 00:00:00

  • Cardiorespiratory fitness and coronary artery calcification in young adults: The CARDIA Study.

    abstract：:Whether cardiorespiratory fitness relates to early subclinical atherosclerotic vascular disease remains unknown. We investigated the relation of cardiorespiratory fitness to coronary artery calcification (CAC) in 2373 African-American and White young adults from the Coronary Artery Risk Development in Young Adults (CA...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2008.06.012

    authors： Lee CD,Jacobs DR Jr,Hankinson A,Iribarren C,Sidney S

    更新日期：2009-03-01 00:00:00

  • Reduced systemic inflammatory response to implantation of sirolimus-eluting stents in patients with stable coronary artery disease.

    abstract：:Stent implantation causes significant injury to the vascular wall, resulting in inflammatory activation. Although sirolimus-eluting stents (SES) have anti-inflammatory properties, their effect on periprocedural systemic inflammatory response has not been sufficiently investigated. Eighty-one patients with stable coron...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.atherosclerosis.2006.08.029

    authors： Kochiadakis GE,Marketou ME,Arfanakis DA,Sfiridaki K,Skalidis EI,Igoumenidis NE,Hamilos MI,Kolyvaki S,Chlouverakis G,Kantidaki E,Castanas E,Vardas PE

    更新日期：2007-10-01 00:00:00

  • Thoracic aortic atherosclerosis in patients with aortic regurgitation.

    abstract：OBJECTIVE:Hemodynamic forces are potential determinants of aortic atherosclerosis. Aortic regurgitation (AR) alters the flow pattern in the aorta. However, the association between AR and aortic atherosclerosis is not well known. METHODS:We assessed the presence, extent and distribution of atherosclerotic lesions in th...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2011.05.026

    authors： Shimoni S,Zilberman L,Edri O,Bar I,Goland S,Gendelman G,Swissa M,Livshitz S,Paz O,Ayzenberg O,George J

    更新日期：2011-09-01 00:00:00

  • Complement proteins and arterial calcification in middle aged women: Cross-sectional effect of cardiovascular fat. The SWAN Cardiovascular Fat Ancillary Study.

    abstract：BACKGROUND:CVD risk increases in women after menopause. Recent data suggest higher levels of complement protein C3 and cardiovascular fat (CF) in postmenopausal women. Whether complement proteins are associated with early markers of atherosclerosis in healthy midlife women has never been evaluated. Additionally, the po...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.atherosclerosis.2015.10.095

    authors： Nagaraj N,Matthews KA,Shields KJ,Barinas-Mitchell E,Budoff MJ,El Khoudary SR

    更新日期：2015-12-01 00:00:00

  • An age-matched computed tomography angiographic study of coronary atherosclerotic plaques in patients with familial hypercholesterolaemia.

    abstract：BACKGROUND AND AIMS:Familial hypercholesterolaemia (FH) is characterised by a high, but variable risk of premature coronary artery disease (CAD). Cardiac computed tomography angiography (CCTA) can be employed to assess subclinical coronary atherosclerosis. We investigated the features and distribution of coronary arter...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2020.03.001

    authors： Pang J,Abraham A,Vargas-García C,Bates TR,Chan DC,Hooper AJ,Bell DA,Burnett JR,Schultz CJ,Watts GF

    更新日期：2020-04-01 00:00:00

  • Rebound inflammatory response during the acute phase of myocardial infarction after simvastatin withdrawal.

    abstract：OBJECTIVE:The present study aimed to verify the existence of a rebound inflammatory effect after statin withdrawal in the acute phase of myocardial infarction (MI). METHODS:In a prospective observational cohort, changes in C-reactive protein (CRP) between the first and the fifth day after MI were evaluated in 249 cons...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2009.04.008

    authors： Sposito AC,Carvalho LS,Cintra RM,Araújo AL,Ono AH,Andrade JM,Coelho OR,Quinaglia e Silva JC,Brasilia Heart Study Group.

    更新日期：2009-11-01 00:00:00

  • Homozygous familial hypercholesterolemic patients in China.

    abstract：:Five homozygous patients with familial hypercholesterolemia (FH) are described. Their serum cholesterol levels were between 603 and 907 mg/dl, with an average of 714 mg/dl. The mean value of serum cholesterol levels of the obligate heterozygous parents was 270 mg/dl. In the patient group, 87% of the serum cholesterol ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(85)90042-5

    authors： Cai HJ,Fan LM,Huang MG,Chen XY,Liu GQ,Chen Q

    更新日期：1985-11-01 00:00:00

  • Aortic size and aortic calcification. A necropsy Study.

    abstract：:Measurements of aortic length and circumference in 336 post-mortem specimens confirm earlier, neglected observations on the progressive increase in aortic size which occurs with advancing years. The increase is not related to atherosclerosis , or to hypertension and seems to be part of a true ageing process. The value...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(77)90162-9

    authors： Mitchell JR,Adams JH

    更新日期：1977-08-01 00:00:00

  • Absence of association between genetic variation in the promoter of the microsomal triglyceride transfer protein gene and plasma lipoproteins in the Framingham Offspring Study.

    abstract：:Microsomal triglyceride transfer protein (MTP) is a lipid transfer protein that is required for the assembly and secretion of very low density lipoproteins (VLDL) by the liver and chylomicrons by the intestine. The common G-493T polymorphism of the MTP promoter has been shown to be associated with decreased plasma LDL...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(99)00281-6

    authors： Couture P,Otvos JD,Cupples LA,Wilson PW,Schaefer EJ,Ordovas JM

    更新日期：2000-02-01 00:00:00

  • One-year clinical outcome after provisional T-stenting for bifurcation lesions with the endothelial progenitor cell capturing stent compared with the bare-metal stent.

    abstract：OBJECTIVE:Currently no data exists regarding the outcomes after the novel endothelial progenitor cell capturing stent (EPCcS) placement in bifurcation lesions using a provisional T-stenting. This study evaluates the 1-year clinical outcome in patients treated with the EPCcS for a bifurcation lesion using a provisional ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2010.09.023

    authors： Beijk MA,Klomp M,Koch KT,Henriques JP,Vis MM,Baan J Jr,Tijssen JG,Piek JJ,de Winter RJ

    更新日期：2010-12-01 00:00:00

  • Expression of long pentraxin PTX3 in human adipose tissue and its relation with cardiovascular risk factors.

    abstract：UNLABELLED:Pentraxin 3 (PTX3) is an acute phase protein strongly expressed by advanced atherosclerotic lesions. We investigated (a) PTX3 expression and secretion in subcutaneous adipose tissue (SAT) and omental visceral adipose tissue (VAT) obtained from 21 obese (37.4+/-8.15 yr) and 10 normal weight subjects (43.7+/-1...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2008.05.015

    authors： Alberti L,Gilardini L,Zulian A,Micheletto G,Peri G,Doni A,Mantovani A,Invitti C

    更新日期：2009-02-01 00:00:00

  • Maximal exercise stress testing in normal and hyperlipidemic children.

    abstract：:Electrocardiographic and cardiovascular responses during maximal exercise were evaluated in 103 normal children and in 82 children with familial hyperlipoproteinemia. The normal and hyperlipidemic children were comparable in regards to age, weight--height index, resting and exercise blood pressures, and maximal workin...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(76)90050-2

    authors： James FW,Glueck CJ,Fallat RW,Millett F,Kaplan S

    更新日期：1976-10-01 00:00:00

  • Carotid and femoral plaque burden is inversely associated with the α-linolenic acid proportion of serum phospholipids in Spanish subjects with primary dyslipidemia.

    abstract：OBJECTIVE:α-Linolenic acid (ALA), the vegetable n-3 fatty acid, appears to have antiatherosclerotic properties akin to those of marine n-3 fatty acids. A prior study in a US population with low fish intake showed an inverse association between ALA intake and carotid plaque. We examined the association between the ALA s...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2010.10.026

    authors： Sala-Vila A,Cofán M,Núñez I,Gilabert R,Junyent M,Ros E

    更新日期：2011-01-01 00:00:00

  • Effects of fenofibrate on lipoproteins, vasomotor function, and serological markers of inflammation, plaque stabilization, and hemostasis.

    abstract：:We investigated the effects of fenofibrate, peroxisome proliferator-activated receptors (PPARs) agonist, on endothelial function in patients with hypertriglyceridemia. We administered placebo or fenofibrate 200 mg daily to 25 patients with hypertriglyceridemia for 8 weeks. This study was randomized, double-blind, plac...

    journal_title：Atherosclerosis

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.atherosclerosis.2004.01.033

    authors： Kon Koh K,Yeal Ahn J,Hwan Han S,Kyu Jin D,Sik Kim H,Cheon Lee K,Kyun Shin E,Sakuma I

    更新日期：2004-06-01 00:00:00

  • Coronary artery calcium and cardiovascular risk in diabetes.

    abstract：:Measurement of coronary artery calcium score (CACS) by electron beam tomography has been shown to a powerful predictor of coronary heart disease events in asymptomatic non-diabetic subjects. In type 2 diabetes, measurement of CACS was found to be a powerful predictor of cardiovascular events which could enhance predic...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,评审

    doi：10.1016/j.atherosclerosis.2009.11.026

    authors： Elkeles RS

    更新日期：2010-06-01 00:00:00

  • Angiopoietins, abdominal aortic aneurysm and atherosclerosis.

    abstract：:Abdominal aortic aneurysm (AAA) and atherosclerosis are common causes of mortality and morbidity in an aging population. Angiogenesis is believed to contribute to the development and progression of these diseases. Angiopoietins (angpts) are known to be important regulators of angiogenesis. Angpts can also influence in...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,评审

    doi：10.1016/j.atherosclerosis.2010.08.051

    authors： Trollope AF,Golledge J

    更新日期：2011-02-01 00:00:00

  • Associations of non-invasive measures of arterial structure and function, and traditional indicators of cardiovascular risk in adults with cerebral palsy.

    abstract：BACKGROUND:Persons with cerebral palsy (CP) have mobility limitations and may be at increased risk for cardiovascular disease (CVD). AIMS:To determine the feasibility of assessing novel CVD risk indicators and to identify predictors of CVD risk in a clinic-based group of adults with CP. METHODS:In an observational st...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2015.09.035

    authors： McPhee PG,Gorter JW,Cotie LM,Timmons BW,Bentley T,MacDonald MJ

    更新日期：2015-12-01 00:00:00

  • Effects of pravastatin on serum adiponectin levels in female patients with type 2 diabetes mellitus.

    abstract：OBJECTIVE:Pravastatin has been reported to elevate circulating adiponectin levels in patients with various insulin resistant state, hypertension, coronary artery disease, and hypercholesterolemia. This study aimed to evaluate whether pravastatin increase serum total and high molecular weight adiponectin levels and impr...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.atherosclerosis.2013.01.045

    authors： Kim JH,Lee MR,Shin JA,Lee SS,Lee JM,You SJ,Yoon KH,Chang SA

    更新日期：2013-04-01 00:00:00

  • Augmented levels of CD44 in macrophages from atherosclerotic subjects: a possible IL-6-CD44 feedback loop?

    abstract：:The cell-adhesion molecule CD44 likely participates in atherosclerosis development. We have shown previously that pro-inflammatory cytokines affect CD44 expression. Therefore, this work examined the role of elevated CD44 levels in human macrophages. Macrophages from human atherosclerotic subjects (n=15) showed elevate...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2006.03.020

    authors： Hägg D,Sjöberg S,Hultén LM,Fagerberg B,Wiklund O,Rosengren A,Carlsson LM,Borén J,Svensson PA,Krettek A

    更新日期：2007-02-01 00:00:00