Clinical implications of intrinsic molecular subtypes of breast cancer for sentinel node status.

abstract：:Segmentation of the vertebrate hindbrain is an evolutionarily conserved process. Here, we identify the transcription factor early growth response 4 (egr4) as a novel regulator of posterior hindbrain development in Xenopus. egr4 is specifically and transiently expressed in rhombomeres 5 and 6 (r5/r6), and Egr4 knockdow...

journal_title：Scientific reports

authors： Bae CJ,Jeong J,Saint-Jeannet JP

更新日期：2015-01-13 00:00:00

abstract：:The abnormal wing discs (awd) gene encodes the Drosophila homolog of NME1/NME2 metastasis suppressor genes. Awd acts in multiple tissues where its function is critical in establishing and maintaining epithelial integrity. Here, we analysed awd gene function in Drosophila epithelial cells using transgene-mediated RNA i...

journal_title：Scientific reports

authors： Romani P,Duchi S,Gargiulo G,Cavaliere V

更新日期：2017-12-04 00:00:00

abstract：:The Sinorhizobium meliloti (S. meliloti) strain CCNWSX0020 displayed tolerance to high levels exposures of multiple metals and growth promotion of legume plants grown in metal-contaminated soil. However, the mechanism of metal-resistant strain remains unknown. We used five P1B-ATPases deletions by designating as ∆copA...

journal_title：Scientific reports

authors： Lu M,Li Z,Liang J,Wei Y,Rensing C,Wei G

更新日期：2016-07-05 00:00:00

abstract：:Musical performance requires extremely fast and dexterous limb movements. The underlying biological mechanisms have been an object of interest among scientists and non-scientists for centuries. Numerous studies of musicians and non-musicians have demonstrated that neuroplastic adaptations through early and deliberate ...

journal_title：Scientific reports

authors： Furuya S,Oku T,Miyazaki F,Kinoshita H

更新日期：2015-10-27 00:00:00

abstract：:Energy plants are the main source of bioenergy which will play an increasingly important role in future energy supplies. With limited cultivated land resources in China, the development of energy plants may primarily rely on the marginal land. In this study, based on the land use data from 1990 to 2010(every 5 years i...

journal_title：Scientific reports

authors： Jiang D,Hao M,Fu J,Zhuang D,Huang Y

更新日期：2014-07-24 00:00:00

abstract：:Structured Progressive Circuit Class Therapy (SPCCT) was developed based on task-oriented therapy, providing benefits to patients' motivation and motor function. Training with Motor Imagery (MI) alone can improve gait performance in stroke survivors, but a greater effect may be observed when combined with SPCCT. Healt...

journal_title：Scientific reports

authors： Bovonsunthonchai S,Aung N,Hiengkaew V,Tretriluxana J

更新日期：2020-04-24 00:00:00

abstract：:Although redox reactions are recognized to fractionate iron (Fe) isotopes, the dominant mechanisms controlling the Fe isotope fractionation and notably the role of organic matter (OM) are still debated. Here, we demonstrate how binding to organic ligands governs Fe isotope fractionation beyond that arising from redox ...

journal_title：Scientific reports

authors： Lotfi-Kalahroodi E,Pierson-Wickmann AC,Rouxel O,Marsac R,Bouhnik-Le Coz M,Hanna K,Davranche M

更新日期：2021-01-21 00:00:00

abstract：:Detection of nitroaromatic explosives with high sensitivity and selectivity is extremely important for civilian and military safety. Here, we report the synthesis and multimodal sensing applications of an emissive alanine based dansyl tagged copolymer P(MMA-co-Dansyl-Ala-HEMA) (DCP), synthesized by RAFT copolymerizati...

journal_title：Scientific reports

authors： Kumar V,Maiti B,Chini MK,De P,Satapathi S

更新日期：2019-05-13 00:00:00

abstract：:The variation in mortality-to-incidence ratios (MIRs) among countries reflects the clinical outcomes and the available interventions for colorectal cancer treatments. The association between MIR of prostate cancer and cancer care disparities among countries is an interesting issue that is rarely investigated. For the ...

journal_title：Scientific reports

authors： Chen SL,Wang SC,Ho CJ,Kao YL,Hsieh TY,Chen WJ,Chen CJ,Wu PR,Ko JL,Lee H,Sung WW

更新日期：2017-01-04 00:00:00

abstract：:The delineation of the molecular pathology underlying amyotrophic lateral sclerosis (ALS) is being hampered by the lack of suitable biomarkers. We have previously reported that bromocriptine upregulates the endogenous antioxidative factor, neuronal apoptosis inhibitory protein (NAIP), sustains motor function and slows...

journal_title：Scientific reports

authors： Kano O,Tanaka K,Kanno T,Iwasaki Y,Ikeda JE

更新日期：2018-01-08 00:00:00

abstract：:The lignite biodegradation procedure to produce water-soluble humic materials (WSHM) with a Penicillium stain was established by previous studies in our laboratory. This study researched the effects of WSHM on the growth of Bradyrhizobium liaoningense CCBAU05525 and its nodulation on soybean. Results showed that WSHM ...

journal_title：Scientific reports

authors： Guo Gao T,Yuan Xu Y,Jiang F,Zhen Li B,Shui Yang J,Tao Wang E,Li Yuan H

更新日期：2015-06-08 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Santarpia JL,Rivera DN,Herrera VL,Morwitzer MJ,Creager HM,Santarpia GW,Crown KK,Brett-Major DM,Schnaubelt ER,Broadhurst MJ,Lawler JV,Reid SP,Lowe JJ

更新日期：2020-08-12 00:00:00

abstract：:Hydrocarbons fuel our economy. Furthermore, intermediate goods and consumer products are often hydrocarbon-based. Beside all the progress they made possible, hydrogen-containing substances can have severe detrimental effects on materials exposed to them. Hydrogen-assisted failure of iron alloys has been recognised mor...

journal_title：Scientific reports

authors： Röhsler A,Sobol O,Hänninen H,Böllinghaus T

更新日期：2020-02-27 00:00:00

abstract：:Human mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME) has a dimer of dimers quaternary structure with two independent allosteric sites in each monomer. Here, we reveal the different effects of nucleotide ligands on the quaternary structure regulation and functional role of the human m-NAD(P)-ME exosite. In ...

journal_title：Scientific reports

authors： Hsieh JY,Shih WT,Kuo YH,Liu GY,Hung HC

更新日期：2019-06-24 00:00:00

abstract：:Long interspersed element-1 (LINE-1, L1) is a mobile genetic element comprising about 17% of the human genome. L1 utilizes an endonuclease to insert L1 cDNA into the target genomic DNA, which induces double-strand DNA breaks in the human genome and activates the DNA damage signaling pathway, resulting in the recruitme...

journal_title：Scientific reports

authors： Ariumi Y,Kawano K,Yasuda-Inoue M,Kuroki M,Fukuda H,Siddiqui R,Turelli P,Tateishi S

更新日期：2018-10-26 00:00:00

abstract：:Until now, the only kind of practical quantum private query (QPQ), quantum-key-distribution (QKD)-based QPQ, focuses on the retrieval of a single bit. In fact, meaningful message is generally composed of multiple adjacent bits (i.e., a multi-bit block). To obtain a message a1a2···al from database, the user Alice has t...

journal_title：Scientific reports

authors： Wei CY,Gao F,Wen QY,Wang TY

更新日期：2014-12-18 00:00:00

abstract：:This study presents a modular-based implementation of augmented reality to provide an immersive experience in learning or teaching the planning phase, control system, and machining parameters of a fully automated work cell. The architecture of the system consists of three code modules that can operate independently or...

journal_title：Scientific reports

authors： Pai YS,Yap HJ,Md Dawal SZ,Ramesh S,Phoon SY

更新日期：2016-06-07 00:00:00

abstract：:The aim of this study was to estimate the incidence of T2DM in three population groups: rural, rural-to-urban migrants and urban dwellers. Data from the PERU MIGRANT Study was analysed. The baseline assessment was conducted in 2007-2008 using a single-stage random sample and further follow-up was undertaken in 2015-16...

journal_title：Scientific reports

authors： Ruiz-Alejos A,Carrillo-Larco RM,Miranda JJ,Anderson CAM,Gilman RH,Smeeth L,Bernabé-Ortiz A

更新日期：2018-04-03 00:00:00

abstract：:We developed an optimal noninvasive index comprising routine laboratory parameters for predicting cirrhosis in chronic hepatitis B (CHB) and chronic hepatitis C (CHC) patients. This study included 992 CHB patients and 1,284 CHC patients who received liver biopsy. We developed the new index, named modified Fibrosis-4 (...

journal_title：Scientific reports

authors： Wang HW,Peng CY,Lai HC,Su WP,Lin CH,Chuang PH,Chen SH,Chen CH,Hsu WF,Huang GT

更新日期：2017-06-12 00:00:00

abstract：:MicroRNAs (MiRNAs) have been found to be dysregulated in lung cancer tissues compared to their matched paracancerous tissues. However, the roles of miRNAs in peripheral blood as potential biomarkers for early diagnosis of lung cancer remain poorly understood. Here we found that miR-33a-5p and miR-128-3p were down-regu...

journal_title：Scientific reports

authors： Pan J,Zhou C,Zhao X,He J,Tian H,Shen W,Han Y,Chen J,Fang S,Meng X,Jin X,Gong Z

更新日期：2018-11-12 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Lopeman RC,Harrison J,Rathbone DL,Desai M,Lambert PA,Cox JAG

更新日期：2020-03-06 00:00:00

abstract：:Several mosquito species have been described as vectors for the Zika virus (ZIKV), such as those in the Aedes, Anopheles, Mansonia and Culex genera. Our previous survey studies were found the ZIKV RNA positive in both male, female and larvae of Culex quinquefasciatus Say and Aedes aegypti (L.) mosquitoes collected fro...

journal_title：Scientific reports

authors： Phumee A,Chompoosri J,Intayot P,Boonserm R,Boonyasuppayakorn S,Buathong R,Thavara U,Tawatsin A,Joyjinda Y,Wacharapluesadee S,Siriyasatien P

更新日期：2019-03-27 00:00:00

abstract：:Neuropeptide Y Y1 receptors (Y1R) have been found to be overexpressed in a number of different tumours, such as breast, ovarian or renal cell cancer. In mammary carcinoma the high Y1R density together with its high incidence of 85% in primary human breast cancers and 100% in breast cancer derived lymph node metastases...

journal_title：Scientific reports

authors： Maschauer S,Ott JJ,Bernhardt G,Kuwert T,Keller M,Prante O

更新日期：2019-09-10 00:00:00

abstract：:The high density nucleation of α-Al2O3 nanocrystallites was observed by rapid heating of the aluminum formate hydroxide-based precursor powder at 1200 °C for 50 s. The nucleation of α-Al2O3 nanocrystallites with less 10 nm in size from high purity aluminum oxide matrix has not been observed to our knowledge. Based on ...

journal_title：Scientific reports

authors： Yoshida M,Kato Y,Oumi Y,Sakurada O,Tanaka M,Wada M,Kitaoka S

更新日期：2019-10-17 00:00:00

abstract：:Mixed fisheries are the dominant type of fishery worldwide. Overexploitation in mixed fisheries occurs when catches continue for available quota species while low quota species are discarded. As EU fisheries management moves to count all fish caught against quota (the "landing obligation"), the challenge is to catch a...

journal_title：Scientific reports

authors： Dolder PJ,Thorson JT,Minto C

更新日期：2018-09-17 00:00:00

abstract：:From mid-May to August 2011, extreme runoff in the Columbia River ranged from 14,000 to over 17,000 m(3)/s, more than two standard deviations above the mean for this period. The extreme runoff was the direct result of both melting of anomalously high snowpack and rainfall associated with the 2010-2011 La Niña. The eff...

journal_title：Scientific reports

authors： Mazzini PL,Risien CM,Barth JA,Pierce SD,Erofeev A,Dever EP,Kosro PM,Levine MD,Shearman RK,Vardaro MF

更新日期：2015-11-26 00:00:00

abstract：:We examined whether blood lead levels (BLLs) were associated with reproductive hormone levels in a cross-sectional study using data from the SPECT-China study. We selected 2286 men and 1571 postmenopausal women without hormone replacement therapy. BLLs, blood cadmium, total testosterone (TT), oestradiol (E2), luteiniz...

journal_title：Scientific reports

authors： Chen C,Wang N,Zhai H,Nie X,Sun H,Han B,Li Q,Chen Y,Cheng J,Xia F,Zhao L,Zheng Y,Shen Z,Lu Y

更新日期：2016-11-29 00:00:00

abstract：:Accurate repair of DNA damage is crucial to ensure genome stability and cell survival of all organisms. Bile functions as a defensive barrier against intestinal colonization by pathogenic microbes. Campylobacter jejuni, a leading bacterial cause of foodborne illness, possess strategies to mitigate the toxic components...

journal_title：Scientific reports

authors： Gourley CR,Negretti NM,Konkel ME

更新日期：2017-10-31 00:00:00

abstract：:The intention of this observational study is to show the significant impact of comorbidities and smoking on the outcome in aneurysmal subarachnoid hemorrhage (SAH). During this observational study 203 cases of treatment of ruptured intracranial aneurysms were analyzed. We examined and classified prospectively the 12 m...

journal_title：Scientific reports

authors： Hammer A,Steiner A,Ranaie G,Yakubov E,Erbguth F,Hammer CM,Killer-Oberpfalzer M,Steiner H,Janssen H

更新日期：2018-08-17 00:00:00

abstract：:During locomotion, the human ankle-foot system dynamically alters its gearing, or leverage of the ankle joint on the ground. Shifting ankle-foot gearing regulates speed of plantarflexor (i.e., calf muscle) contraction, which influences economy of force production. Here, we tested the hypothesis that manipulating ankle...

journal_title：Scientific reports

authors： Ray SF,Takahashi KZ

更新日期：2020-05-29 00:00:00