Impact of Comorbidities and Smoking on the Outcome in Aneurysmal Subarachnoid Hemorrhage.

abstract：:We developed a simple, scalable and high-throughput method for fabrication of large-area three-dimensional rose-like microflowers with controlled size, shape and density on graphene films by femtosecond laser micromachining. The novel biomimetic microflower that composed of numerous turnup graphene nanoflakes can be f...

journal_title：Scientific reports

authors： Shi X,Li X,Jiang L,Qu L,Zhao Y,Ran P,Wang Q,Cao Q,Ma T,Lu Y

更新日期：2015-11-30 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is a disease marked by the development of skeletal muscle weakness and wasting. DMD results from mutations in the gene for the cytoskeletal protein dystrophin. The loss of dystrophin expression is not limited to muscle weakness but has multiple systemic consequences. Managing the nutr...

journal_title：Scientific reports

authors： Strakova J,Kamdar F,Kulhanek D,Razzoli M,Garry DJ,Ervasti JM,Bartolomucci A,Townsend D

更新日期：2018-09-11 00:00:00

abstract：:In bacteria, selective promoter recognition by RNA polymerase is achieved by its association with σ factors, accessory subunits able to direct RNA polymerase "core enzyme" (E) to different promoter sequences. Using Chromatin Immunoprecipitation-sequencing (ChIP-seq), we searched for promoters bound by the σ(S)-associa...

journal_title：Scientific reports

authors： Peano C,Wolf J,Demol J,Rossi E,Petiti L,De Bellis G,Geiselmann J,Egli T,Lacour S,Landini P

更新日期：2015-05-28 00:00:00

abstract：:In this work layered copper films with smooth surface were successfully fabricated onto ITO substrate by electrochemical deposition (ECD) and the thickness of the films was nearly 60 nm. The resulting films were characterized by SEM, TEM, AFM, XPS, and XRD. We have investigated the effects of potential and the concent...

journal_title：Scientific reports

authors： Wei C,Wu G,Yang S,Liu Q

更新日期：2016-10-13 00:00:00

abstract：:Ammonia physiology is important to numerous disease states including urea cycle disorders and hepatic encephalopathy. However, many unknowns persist regarding the ammonia response to common and potentially significant physiologic influences, such as food. Our aim was to evaluate the dynamic range of ammonia in respons...

journal_title：Scientific reports

authors： Spacek LA,Strzepka A,Saha S,Kotula J,Gelb J,Guilmain S,Risby T,Solga SF

更新日期：2018-02-07 00:00:00

abstract：:Because of the scanty pipeline of antibiotics newly obtained from nature, chemical modification of established drugs is one of the major streams of current antibacterial research. Intuitive and easy-to-use assays are critical for identifying drug candidates with novel modes of action. In this study, we demonstrated th...

journal_title：Scientific reports

authors： Sugimoto A,Maeda A,Itto K,Arimoto H

更新日期：2017-04-25 00:00:00

abstract：:Daily life stress is an omnipresent phenomenon in modern society. Research has linked prolonged activation of the hypothalamic-pituitary-adrenal axis to psychiatric and somatic diseases. Everyday stressors substantially contribute to these health risks. Despite the notion that the physiological stress response is high...

journal_title：Scientific reports

authors： Linz R,Singer T,Engert V

更新日期：2018-10-18 00:00:00

abstract：:Sea-surface temperature (SST) warming events, which are projected to increase in frequency and intensity with climate change, represent major threats to coral reefs. How these events impact reef carbonate budgets, and thus the capacity of reefs to sustain vertical growth under rising sea levels, remains poorly quantif...

journal_title：Scientific reports

authors： Perry CT,Morgan KM

更新日期：2017-01-13 00:00:00

abstract：:Circular RNA (circRNA) is a newly discovered non-coding RNA, which play significant roles in the function and transcriptional regulation of microRNA. To date, in Chinese cabbage, the functional characteristic of circRNAs in response to calcium deficiency-induced tip-burn have not been reported. In this study, 730 circ...

journal_title：Scientific reports

authors： Wang W,Wang J,Wei Q,Li B,Zhong X,Hu T,Hu H,Bao C

更新日期：2019-10-10 00:00:00

abstract：:Metal-insulator transition is observed in the La0.8Sr0.2MnO3 thin films with thickness larger than 5 unit cells. Insulating phase at lower temperature appeared in the ultrathin films with thickness ranging from 6 unit cells to 10 unit cells and it is found that the Mott variable range hopping conduction dominates in t...

journal_title：Scientific reports

authors： Feng Y,Jin KJ,Gu L,He X,Ge C,Zhang QH,He M,Guo QL,Wan Q,He M,Lu HB,Yang G

更新日期：2016-03-01 00:00:00

abstract：:Evolutionary processes, speciation in woody bamboos are presently little understood. Here we used Dendrocalamus sinicus Chia & J.L. Sun as a model species to investigate dispersal or vicariance speciation in woody bamboos. Variation in three chloroplast DNA (cpDNA) fragments and eight simple sequence repeat markers (S...

journal_title：Scientific reports

authors： Yang JB,Dong YR,Wong KM,Gu ZJ,Yang HQ,Li Z

更新日期：2018-11-16 00:00:00

abstract：:Evidence suggest that overexpression of hypoxia-inducible factor-1α (HIF-1α) is linked to multidrug resistance of epilepsy. Here we explored whether aberrant expression of HIF-1α is regulated by miRNAs. Genome-wide microRNA expression profiling was performed on temporal cortex resected from mesial temporal lobe epilep...

journal_title：Scientific reports

authors： Li Y,Huang C,Feng P,Jiang Y,Wang W,Zhou D,Chen L

更新日期：2016-08-24 00:00:00

abstract：:Peptides derived from the N-terminal heptad repeat (NHR) of HIV-1 gp41 can be potent inhibitors against viral entry when presented in a nonaggregating trimeric coiled-coil conformation via the introduction of exogenous trimerization motifs and intermolecular disulfide bonds. We recently discovered that crosslinking is...

journal_title：Scientific reports

authors： Wang C,Li X,Yu F,Lu L,Jiang X,Xu X,Wang H,Lai W,Zhang T,Zhang Z,Ye L,Jiang S,Liu K

更新日期：2016-08-26 00:00:00

abstract：:The parasitic salmon louse, and its resistance to chemical delousing agents, represents one of the largest challenges to the salmon aquaculture industry. We genotyped lice sampled from wild salmon and sea trout throughout Norway with the recently identified Phe362Tyr mutation that conveys resistance to organophosphate...

journal_title：Scientific reports

authors： Fjørtoft HB,Besnier F,Stene A,Nilsen F,Bjørn PA,Tveten AK,Finstad B,Aspehaug V,Glover KA

更新日期：2017-10-27 00:00:00

abstract：:MicroRNAs play critical role in the development and progression of various diseases. Predicting potential miRNA-disease associations from vast amount of biological data is an important problem in the biomedical research. Considering the limitations in previous methods, we developed Regularized Least Squares for MiRNA-...

journal_title：Scientific reports

authors： Chen X,Yan GY

更新日期：2014-06-30 00:00:00

abstract：:Despite the detailed characterization of the inflammatory and endothelial changes observed in Sickle Cell Disease (SCD), the hierarchical relationship between elements involved in the pathogenesis of this complex disease is yet to be described. Meta-analyses of gene expression studies from public repositories represen...

journal_title：Scientific reports

authors： Hounkpe BW,Fiusa MM,Colella MP,da Costa LN,Benatti Rde O,Saad ST,Costa FF,dos Santos MN,De Paula EV

更新日期：2015-12-09 00:00:00

abstract：:The majority of colorectal cancer (CRC) arises from precursor lesions known as polyps. The molecular determinants that distinguish benign from malignant polyps remain unclear. To molecularly characterize polyps, we utilized Cancer Adjacent Polyp (CAP) and Cancer Free Polyp (CFP) patients. CAPs had tissues from the res...

journal_title：Scientific reports

authors： Druliner BR,Wang P,Bae T,Baheti S,Slettedahl S,Mahoney D,Vasmatzis N,Xu H,Kim M,Bockol M,O'Brien D,Grill D,Warner N,Munoz-Gomez M,Kossick K,Johnson R,Mouchli M,Felmlee-Devine D,Washechek-Aletto J,Smyrk T,Oberg A,

更新日期：2018-02-16 00:00:00

abstract：:Zircon of crustal origin found in mantle-derived rocks is of great interest because of the information it may provide about crust recycling and mantle dynamics. Consideration of this requires understanding of how mantle temperatures, notably higher than zircon crystallization temperatures, affected the recycled zircon...

journal_title：Scientific reports

authors： Bea F,Montero P,Palma JFM

更新日期：2018-08-27 00:00:00

abstract：:Wooden shipwrecks are a significant part of the underwater cultural heritage. In 2007, the Nanhai No. 1 shipwreck was salvaged from the seabed and moved into the Marine Silk Road Museum, where it is still stored in a water tank. We analysed the microbial communities colonizing the hull surface of the Nanhai No. 1 ship...

journal_title：Scientific reports

authors： Liu Z,Fu T,Hu C,Shen D,Macchioni N,Sozzi L,Chen Y,Liu J,Tian X,Ge Q,Feng Z,Liu H,Zhang Z,Pan J

更新日期：2018-05-08 00:00:00

abstract：:At the center of a collapsing hole lies a singularity, a point of infinite curvature where the governing equations break down. It is a topic of fundamental physical interest to clarify the dynamics of fluids approaching such singularities. Here, we use scaling arguments supported by high-fidelity simulations to analyz...

journal_title：Scientific reports

authors： Lu J,Corvalan CM

更新日期：2019-10-10 00:00:00

abstract：:Many human introns carry out a function, in the sense that they are critical to maintain normal cellular activity. Their identification is fundamental to understanding cellular processes and disease. However, being noncoding elements, such functional introns are poorly predicted based on traditional approaches of sequ...

journal_title：Scientific reports

authors： Chorev M,Joseph Bekker A,Goldberger J,Carmel L

更新日期：2017-06-23 00:00:00

abstract：:In specific cases, chromatin clearly forms long-range loops that place distant regulatory elements in close proximity to transcription start sites, but we have limited understanding of many loops identified by Chromosome Conformation Capture (such as Hi-C) analyses. In efforts to elucidate their characteristics and fu...

journal_title：Scientific reports

authors： Sobhy H,Kumar R,Lewerentz J,Lizana L,Stenberg P

更新日期：2019-03-14 00:00:00

abstract：:The success of mesenchymal stem cell transplantation is highly dependent on their survival and controlled fate regulation. This study demonstrates that dual-delivery of connective tissue growth factor (CTGF) and fibroblast growth factor 2 (FGF-2) from a core-shell fiber of Silk Fibroin/poly(L-lactic acid-co-ε-caprolac...

journal_title：Scientific reports

authors： Xu R,Zhao H,Muhammad H,Dong M,Besenbacher F,Chen M

更新日期：2017-08-17 00:00:00

abstract：:The combustion of candles exhibits a variety of dynamical behaviors. Binding several candles together will result in flickering of candle flames, which is generally described as a nonlinear oscillator. The impact on the frequency of the flame by several factors, such as the arrangement, the number and the asymmetry of...

journal_title：Scientific reports

authors： Chen T,Guo X,Jia J,Xiao J

更新日期：2019-01-23 00:00:00

abstract：:Ocean warming with climate change is forcing marine organisms to shift their distributions polewards and phenology. In warm tropical seas, evolutionary adaptation by local species to warming will be crucial to avoid predicted desertification and reduction in diversity. However, little is known about the adaptation of ...

journal_title：Scientific reports

authors： Jin P,Agustí S

更新日期：2018-12-11 00:00:00

abstract：:A series of novel dioxin-containing pyrazoline derivatives with thiourea skeleton have been designed, synthesized and evaluated for their EGFR/HER-2 inhibitory and anti-proliferation activities. A majority of them displayed selective HER-2 inhibitory activity against EGFR inhibitory activity. Compound C20 displayed th...

journal_title：Scientific reports

authors： Yang B,Yang YS,Yang N,Li G,Zhu HL

更新日期：2016-06-08 00:00:00

abstract：:An in-depth focused study of specific cases of patients with recurrent thrombosis may help to identify novel circumstances, genetic and acquired factors contributing to the development of this disorder. The aim of this study was to carry out a detailed and sequential analysis of samples from a patient suffering from e...

journal_title：Scientific reports

authors： Revilla N,de la Morena-Barrio ME,Miñano A,López-Gálvez R,Toderici M,Padilla J,García-Avello Á,Lozano ML,Lefeber DJ,Corral J,Vicente V

更新日期：2017-03-17 00:00:00

abstract：:A novel flexible electret membrane, exhibiting persistent electrostatic effect, distinctive temperature stability and outstanding capability of resistance to harsh environment and fatigue, is demonstrated by experiment. Its excellent electret performance is correlated to the synergy of three factors, which are space c...

journal_title：Scientific reports

authors： Huiming X,Gangjin C,Xumin C,Zhi C

更新日期：2017-08-16 00:00:00

abstract：:In eye movement perimetry (EMP), the saccadic reaction time (SRT) to 'seen' visual stimuli are delayed in glaucoma. Evaluating SRT behaviour in hemi-field sectors could refine its clinical implication. The development phase included 60 controls retrospectively and for the test cohort in evaluation phase, another 30 he...

journal_title：Scientific reports

authors： Mazumdar D,Meethal NSK,George R,Pel JJM

更新日期：2021-01-29 00:00:00

abstract：:The brown alga Fucus vesiculosus is a keystone marine species, which is subject to heavy surface colonisation. This study was designed to analyse the surface epibiome of F. vesiculosus in conjunction with the composition and spatial distribution of its surface metabolome. The amplicon sequencing, SEM and CARD-FISH ima...

journal_title：Scientific reports

authors： Parrot D,Blümel M,Utermann C,Chianese G,Krause S,Kovalev A,Gorb SN,Tasdemir D

更新日期：2019-01-31 00:00:00