当前位置： SCI文献检索 > Scientific Reports期刊下所有文献 > Development and external validation of a novel multihematoma fuzzy sign on computed tomography for predicting traumatic intraparenchymal hematoma expansion.

Development and external validation of a novel multihematoma fuzzy sign on computed tomography for predicting traumatic intraparenchymal hematoma expansion.

Abstract：

:Acute traumatic intraparenchymal hematoma (tICH) expansion is a devastating neurological complication that is associated with poor outcome after cerebral contusion. This study aimed to develop and validate a novel noncontrast computed tomography (CT) (NCCT) multihematoma fuzzy sign to predict acute tICH expansion. In this multicenter, prospective cohort study, multihematoma fuzzy signs on baseline CT were found in 212 (43.89%) of total 482 patients. Patients with the multihematoma fuzzy sign had a higher frequency of tICH expansion than those without (90.79% (138) vs. 46.71% (71)). The presence of multihematoma fuzzy sign was associated with increased risk for acute tICH expansion in entire cohort (odds ratio [OR]: 16.15; 95% confidence interval (CI) 8.85-29.47; P < 0.001) and in the cohort after propensity-score matching (OR: 9.37; 95% CI 4.52-19.43; P < 0.001). Receiver operating characteristic analysis indicated a better discriminative ability of the presence of multihematoma fuzzy sign for acute tICH expansion (AUC = 0.79; 95% CI 0.76-0.83), as was also observed in an external validation cohort (AUC = 0.76; 95% CI 0.67-0.84). The novel NCCT marker of multihematoma fuzzy sign could be easily identified on baseline CT and is an easy-to-use predictive tool for tICH expansion in the early stage of cerebral contusion.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Sheng J,Yang J,Cai S,Zhuang D,Li T,Chen X,Wang G,Dai J,Ding F,Tian L,Zheng F,Tian F,Huang M,Li K,Chen W

doi

10.1038/s41598-021-81685-8

subject

Has Abstract

pub_date

2021-01-21 00:00:00

pages

2042

issue

1

issn

2045-2322

pii

10.1038/s41598-021-81685-8

journal_volume

11

pub_type

杂志文章

相关文献

Scientific Reports文献大全
  • Climatic and environmental aspects of the Mongol withdrawal from Hungary in 1242 CE.

    abstract：:The Mongol invasion of Eastern Europe, and especially its sudden withdrawal from Hungary in 1242 CE, has generated much speculation and an array of controversial theories. None of them, however, considered multifaceted environmental drivers and the coupled analysis of historical reports and natural archives. Here we i...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep25606

    authors： Büntgen U,Di Cosmo N

    更新日期：2016-05-26 00:00:00

  • Topology of chromosome centromeres in human sperm nuclei with high levels of DNA damage.

    abstract：:Several studies have shown that the 'poor' sperm DNA quality appears to be an important factor affecting male reproductive ability. In the case of sperm cells from males with the correct somatic karyotype but with deficient spermatogenesis, resulting in a high degree of sperm DNA fragmentation, we observed changes in ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep31614

    authors： Wiland E,Fraczek M,Olszewska M,Kurpisz M

    更新日期：2016-08-25 00:00:00

  • Effects of mechanical stress on chondrocyte phenotype and chondrocyte extracellular matrix expression.

    abstract：:Mechanical factors play a key role in regulating the development of cartilage degradation in osteoarthritis. This study aimed to identify the influence of mechanical stress in cartilage and chondrocytes. To explore the effects of mechanical stress on cartilage morphology, we observed cartilages in different regions by...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep37268

    authors： Liu Q,Hu X,Zhang X,Duan X,Yang P,Zhao F,Ao Y

    更新日期：2016-11-17 00:00:00

  • Rising temperatures may drive fishing-induced selection of low-performance phenotypes.

    abstract：:Climate warming is likely to interact with other stressors to challenge the physiological capacities and survival of phenotypes within populations. This may be especially true for the billions of fishes per year that undergo vigorous exercise prior to escaping or being intentionally released from fishing gear. Using a...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep40571

    authors： Clark TD,Messmer V,Tobin AJ,Hoey AS,Pratchett MS

    更新日期：2017-01-17 00:00:00

  • Topological phase transition without gap closing.

    abstract：:Topological phase transition is accompanied with a change of topological numbers. According to the bulk-edge correspondence, the gap closing and the breakdown of the adiabaticity are necessary at the phase transition point to make the topological number ill-defined. However, the gap closing is not always needed. In th...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep02790

    authors： Ezawa M,Tanaka Y,Nagaosa N

    更新日期：2013-09-27 00:00:00

  • X-ray diffraction reveals the intrinsic difference in the physical properties of membrane and soluble proteins.

    abstract：:Membrane proteins are distinguished from soluble proteins by their insertion into biological membranes. This insertion is achieved via a noticeable arrangement of hydrophobic amino acids that are exposed at the surface of the protein, and renders the interaction with the aliphatic tails of lipids more energetically fa...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-17216-1

    authors： Robert X,Kassis-Sahyoun J,Ceres N,Martin J,Sawaya MR,Read RJ,Gouet P,Falson P,Chaptal V

    更新日期：2017-12-05 00:00:00

  • A Semi-Continuous Process For Polyphenols Extraction From Sea Buckthorn Leaves.

    abstract：:Sea buckthorn (Hippophae Rhamnoides L.) is an important source of bioactive compounds such as: antioxidants, vitamins, fatty acids, amino acids, and minerals. Sea buckthorn leaves extracts have been proved to have anti-microbial, antioxidant, anti-inflammatory, and anti-viral properties. In this paper, the extraction ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-48610-6

    authors： Asofiei I,Calinescu I,Trifan A,Gavrila AI

    更新日期：2019-08-19 00:00:00

  • Focused Ultrasound-enabled Brain Tumor Liquid Biopsy.

    abstract：:Although blood-based liquid biopsies have emerged as a promising non-invasive method to detect biomarkers in various cancers, limited progress has been made for brain tumors. One major obstacle is the blood-brain barrier (BBB), which hinders efficient passage of tumor biomarkers into the peripheral circulation. The ob...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-24516-7

    authors： Zhu L,Cheng G,Ye D,Nazeri A,Yue Y,Liu W,Wang X,Dunn GP,Petti AA,Leuthardt EC,Chen H

    更新日期：2018-04-26 00:00:00

  • Role of phosphatase of regenerating liver 1 (PRL1) in spermatogenesis.

    abstract：:The PRL phosphatases are oncogenic when overexpressed but their in vivo biological function is less well understood. Previous gene deletion study revealed a role for PRL2 in spermatogenesis. We report here the first knockout mice lacking PRL1, the most related homolog of PRL2. We found that loss of PRL1 does not affec...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep34211

    authors： Bai Y,Zhou HM,Zhang L,Dong Y,Zeng Q,Shou W,Zhang ZY

    更新日期：2016-09-26 00:00:00

  • Kaempferol stimulates gene expression of low-density lipoprotein receptor through activation of Sp1 in cultured hepatocytes.

    abstract：:A high level of plasma low-density lipoprotein (LDL) cholesterol is considered a risk factor for atherosclerosis. Because the hepatic LDL receptor (LDLR) is essential for clearing plasma LDL cholesterol, activation of LDLR is a promising therapeutic target for patients with atherosclerotic disease. Here we demonstrate...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep24940

    authors： Ochiai A,Miyata S,Iwase M,Shimizu M,Inoue J,Sato R

    更新日期：2016-04-25 00:00:00

  • Usefulness and limitations of sample pooling for environmental DNA metabarcoding of freshwater fish communities.

    abstract：:Environmental DNA (eDNA) metabarcoding has been used increasingly to assess biodiversity of aquatic vertebrates. However, there still remains to be developed a sampling design of eDNA metabarcoding that can ensure high detection rates of species with minimum total survey effort, especially for large-scale surveys of a...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-14978-6

    authors： Sato H,Sogo Y,Doi H,Yamanaka H

    更新日期：2017-11-01 00:00:00

  • Near-infrared roll-off-free electroluminescence from highly stable diketopyrrolopyrrole light emitting diodes.

    abstract：:Organic light emitting diodes (OLEDs) operating in the near-infrared spectral region are gaining growing relevance for emerging photonic technologies, such as lab-on-chip platforms for medical diagnostics, flexible self-medicated pads for photodynamic therapy, night vision and plastic-based telecommunications. The ach...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep34096

    authors： Sassi M,Buccheri N,Rooney M,Botta C,Bruni F,Giovanella U,Brovelli S,Beverina L

    更新日期：2016-09-28 00:00:00

  • Differential Inhibition of Human and Trypanosome Ubiquitin E1S by TAK-243 Offers Possibilities for Parasite Selective Inhibitors.

    abstract：:Novel strategies to target Trypanosoma brucei, Trypanosoma cruzi and Leishmania are urgently needed to generate better and safer drugs against Human African Trypanosomiasis, Chagas disease and Leishmaniasis, respectively. Here, we investigated the feasibility of selectively targeting in trypanosomatids the ubiquitin E...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-52618-3

    authors： Boer DR,Bijlmakers MJ

    更新日期：2019-11-07 00:00:00

  • Identification and characterisation of the novel endogenous promoter HASP1 and its signal peptide from Phaeodactylum tricornutum.

    abstract：:Although diatoms have been extensively studied as bioreactors, only a limited number of efficient gene promoters are available. Therefore, the development of new endogenous promoters is important for the heterologous production of a variety of recombinant proteins. Herein, we identified the most abundant secreted prot...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-45786-9

    authors： Erdene-Ochir E,Shin BK,Kwon B,Jung C,Pan CH

    更新日期：2019-07-09 00:00:00

  • Temperature-dependent changes in neuronal dynamics in a patient with an SCN1A mutation and hyperthermia induced seizures.

    abstract：:Dravet syndrome is the prototype of SCN1A-mutation associated epilepsies. It is characterised by prolonged seizures, typically provoked by fever. We describe the evaluation of an SCN1A mutation in a child with early-onset temperature-sensitive seizures. The patient carries a heterozygous missense variant (c3818C > T; ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep31879

    authors： Peters C,Rosch RE,Hughes E,Ruben PC

    更新日期：2016-09-01 00:00:00

  • Sporadic colon cancer murine models demonstrate the value of autoantibody detection for preclinical cancer diagnosis.

    abstract：:Although autoantibody detection has been proposed for diagnosis of colorectal cancer, little is known about their initial production and development correlation with cancer progression. Azoxymethane/dextran sodium sulfate (AOM/DSS)-treated mice developed colon adenocarcinoma in the distal colon similar to human sporad...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep02938

    authors： Barderas R,Villar-Vázquez R,Fernández-Aceñero MJ,Babel I,Peláez-García A,Torres S,Casal JI

    更新日期：2013-10-15 00:00:00

  • Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease.

    abstract：:Studies have assessed individual components of a western diet, but no study has assessed the long-term, cumulative effects of a western diet on aging and Alzheimer's disease (AD). Therefore, we have formulated the first western-style diet that mimics the fat, carbohydrate, protein, vitamin and mineral levels of wester...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep21568

    authors： Graham LC,Harder JM,Soto I,de Vries WN,John SW,Howell GR

    更新日期：2016-02-18 00:00:00

  • Neurite regrowth stimulation by a red-light spot focused on the neuronal cell soma following blue light-induced retraction.

    abstract：:The interaction of light with biological tissues has been considered for various therapeutic applications. Light-induced neurite growth has the potential to be a clinically useful technique for neuron repair. However, most previous studies used either a large illumination area to accelerate overall neurite growth or e...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-54687-w

    authors： Kao YC,Liao YC,Cheng PL,Lee CH

    更新日期：2019-12-03 00:00:00

  • Estimation of elevated intracranial pressure in infants with hydroce-phalus by using transcranial Doppler velocimetry with fontanel compression.

    abstract：:For infants with acute progressive hydrocephalus, invasive drainage of cerebrospinal fluid (CSF) is performed until a ventriculo-peritoneal shunt can be inserted. Surrogate markers of intracranial pressure (ICP) may help optimise the timing of invasive procedures. To assess whether RI with/without fontanel compression...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-30274-3

    authors： Yoshizuka T,Kinoshita M,Iwata S,Tsuda K,Kato T,Saikusa M,Shindou R,Hara N,Harada E,Takashima S,Takeshige N,Saitoh S,Yamashita Y,Iwata O

    更新日期：2018-08-07 00:00:00

  • Molecularly imprinted polymer decorated nanoporous gold for highly selective and sensitive electrochemical sensors.

    abstract：:Electrochemical nanosensors based on nanoporous gold leaf (NPGL) and molecularly imprinted polymer (MIP) are developed for pharmaceutical analysis by using metronidazole (MNZ) as a model analyte. NPGL, serving as the loading platform for MIP immobilization, possesses large accessible surface area with superb electric ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep07699

    authors： Li Y,Liu Y,Liu J,Liu J,Tang H,Cao C,Zhao D,Ding Y

    更新日期：2015-01-09 00:00:00

  • Mechanism of splenic cell death and host mortality in a Plasmodium yoelii malaria model.

    abstract：:Malaria is a fatal disease that displays a spectrum of symptoms and severity, which are determined by complex host-parasite interactions. It has been difficult to study the effects of parasite strains on disease severity in human infections, but the mechanisms leading to specific disease phenotypes can be investigated...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-10776-2

    authors： Lacerda-Queiroz N,Riteau N,Eastman RT,Bock KW,Orandle MS,Moore IN,Sher A,Long CA,Jankovic D,Su XZ

    更新日期：2017-09-05 00:00:00

  • Enhancement of Colonic Absorptive Function after the Massive Resection of the Small Intestine Based on the Creation of an Artificial Colonic Valve.

    abstract：:The colon can have an absorptive function similar to that of the small intestine after the massive resection of the small bowel. To improve colonic absorptive function, we created a valve in the colon (artificial colonic valve, ACV). ACVs were created in 20 rats that had 80 percent of their small intestine resected, w...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-57865-3

    authors： Deng G,Deng Z

    更新日期：2020-01-21 00:00:00

  • Local entrainment of oscillatory activity induced by direct brain stimulation in humans.

    abstract：:In a quest for direct evidence of oscillation entrainment, we analyzed intracerebral electroencephalographic recordings obtained during intracranial electrical stimulation in a cohort of three medication-resistant epilepsy patients tested pre-surgically. Spectral analyses of non-epileptogenic cerebral sites stimulated...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep41908

    authors： Amengual JL,Vernet M,Adam C,Valero-Cabré A

    更新日期：2017-03-03 00:00:00

  • Relationship Between Homodimeric Glucocorticoid Receptor and Transcriptional Regulation Assessed via an In Vitro Fluorescence Correlation Spectroscopy-Microwell System.

    abstract：:Glucocorticoid receptor (GR) is a hormone-activated transcription regulatory protein involved in metabolism as well as adrenocortical responses to psychosocial stress. Ligand-activated GR localizes to the nucleus, where GR homodimers regulate gene transcription via direct binding to glucocorticoid response elements (G...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-25393-w

    authors： Oasa S,Mikuni S,Yamamoto J,Kurosaki T,Yamashita D,Kinjo M

    更新日期：2018-05-10 00:00:00

  • Deep structural brain lesions associated with consciousness impairment early after hemorrhagic stroke.

    abstract：:The purpose of this study was to determine the significance of deep structural lesions for impairment of consciousness following hemorrhagic stroke and recovery at ICU discharge. Our study focused on deep lesions that previously were implicated in studies of disorders of consciousness. We analyzed MRI measures obtaine...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-41042-2

    authors： Rohaut B,Doyle KW,Reynolds AS,Igwe K,Couch C,Matory A,Rizvi B,Roh D,Velazquez A,Megjhani M,Park S,Agarwal S,Mauro CM,Li G,Eliseyev A,Perlbarg V,Connolly S,Brickman AM,Claassen J

    更新日期：2019-03-12 00:00:00

  • Nutrient allocation strategies of woody plants: an approach from the scaling of nitrogen and phosphorus between twig stems and leaves.

    abstract：:Allocation of limited nutrients, such as nitrogen (N) and phosphorus (P), among plant organs reflects the influences of evolutionary and ecological processes on functional traits of plants, and thus is related to functional groups and environmental conditions. In this study, we tested this hypothesis by exploring the ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep20099

    authors： Yan Z,Li P,Chen Y,Han W,Fang J

    更新日期：2016-02-05 00:00:00

  • Hair organ regeneration via the bioengineered hair follicular unit transplantation.

    abstract：:Organ regenerative therapy aims to reproduce fully functional organs to replace organs that have been lost or damaged as a result of disease, injury, or aging. For the fully functional regeneration of ectodermal organs, a concept has been proposed in which a bioengineered organ is developed by reproducing the embryoni...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep00424

    authors： Asakawa K,Toyoshima KE,Ishibashi N,Tobe H,Iwadate A,Kanayama T,Hasegawa T,Nakao K,Toki H,Noguchi S,Ogawa M,Sato A,Tsuji T

    更新日期：2012-01-01 00:00:00

  • 3D hindlimb joint mobility of the stem-archosaur Euparkeria capensis with implications for postural evolution within Archosauria.

    abstract：:Triassic archosaurs and stem-archosaurs show a remarkable disparity in their ankle and pelvis morphologies. However, the implications of these different morphologies for specific functions are still poorly understood. Here, we present the first quantitative analysis into the locomotor abilities of a stem-archosaur app...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-70175-y

    authors： Demuth OE,Rayfield EJ,Hutchinson JR

    更新日期：2020-09-21 00:00:00

  • Engineering of soybean mosaic virus as a versatile tool for studying protein-protein interactions in soybean.

    abstract：:Transient gene expression approaches are valuable tools for rapid introduction of genes of interest and characterization of their functions in plants. Although agroinfiltration is the most effectively and routinely used method for transient expression of multiple genes in various plant species, this approach has been ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep22436

    authors： Seo JK,Choi HS,Kim KH

    更新日期：2016-02-29 00:00:00

  • New Immunosuppressive Sphingoid Base and Ceramide Analogues in Wild Cordyceps.

    abstract：:A comprehensive identification of sphingoid bases and ceramides in wild Cordyceps was performed by integrating a sequential chromatographic enrichment procedure and an UHPLC-ultrahigh definition-Q-TOF-MS based sphingolipidomic approach. A total of 43 sphingoid bases and 303 ceramides were identified from wild Cordycep...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep38641

    authors： Mi JN,Han Y,Xu Y,Kou J,Wang JR,Jiang ZH

    更新日期：2016-12-14 00:00:00