Abstract：
:Multiple Myeloma (MM) is a neoplastic disorder derived from the malignant proliferation of monoclonal plasma cells. It is characterized by the overproduction of immunoglobulins (Ig). We report a rare case in which bulbar palsy was the initial manifestation of IgG-MM. A 66-year-old woman initially presented with progressive dysphagia and dysarthria for half a year. Physical examination demonstrated a deviation of the uvula, difficulty in protruding tongue, and bilateral tongue atrophy. Laboratory assessments revealed anemia and prominent monoclonal elevation of IgG levels both in serum and cerebrospinal fluid (CSF). The diagnosis of IgG-MM was confirmed by the identification of plasmacytosis in bone marrow aspiration and biopsy and elevation of γ-M protein in serum protein electrophoresis (SPEP). Therefore, the patient began to receive the chemotherapy with PAD (bortezomib-doxorubicin-dexamethasone) regimen. Her condition had been under control. MM as a hematological malignancy can affect cranial nerves and present as chronic progressive bulbar palsy.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Li S,Gao F,Cheng W,Wang Sdoi
10.1016/j.jnma.2020.12.007subject
Has Abstractpub_date
2021-01-18 00:00:00eissn
0027-9684issn
1943-4693pii
S0027-9684(20)30460-0pub_type
abstract：:We examined associations of weight concerns and weight gain with adolescent tobacco cessation treatment and whether these effects differed by gender or ethnoracial group. Participants were 115 urban adolescents recruited for a randomized clinical trial of nicotine replacement therapy. Baseline weight gain concerns wer...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,随机对照试验
doi：10.1016/s0027-9684(15)31067-1
更新日期：2009-10-01 00:00:00
abstract：:Peritoneal lavage fluid for cytologic study was obtained in 73 patients undergoing primary surgery for stage I endometrial adenocarcinoma. Preoperative irradiation was not used. Malignant cells consistent with endometrial adenocarcinoma were present in eight (11 percent) cases. There was no significant difference in t...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1985-10-01 00:00:00
abstract：:Malaria continues to be a cause of high mortality and morbidity. Imported cases of malaria are increasing in New York City. Yet, New York physicians, when evaluating patients for fever, frequently missed the diagnosis of malaria. We evaluated the role of platelet count for predicting malarial infection. The study incl...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
abstract：:The psychosocial adjustment of patients who are experiencing physical disabilities is examined within the context of a family ecological approach. Historical and sociocultural characteristics of African-American families are delineated and explored in terms of their potentially positive impact on the adjustment proces...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1994-12-01 00:00:00
abstract：BACKGROUND/PURPOSE:With the urgency to create more equitable health care, increased research and early exposure to health interventions and clinical medicine are imperative. Health disparities continue to persist nationwide, particularly in underserved areas and among traditionally disadvantaged populations. In additio...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2019.12.003
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVE:To identify social, behavioral and epidemiologic factors associated with HIV infection among HIV-infected and HIV-uninfected black women residing in North Carolina. DESIGN:A case-control study conducted in August 2004 in North Carolina. METHODS:Cases were 18-40-year-old women with HIV infections diagnosed f...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
abstract：:Very low birthweight and preterm delivery explain two thirds of the excess deaths experienced by African-American infants. Although comprehensive, good quality services for all African-American women will help to reduce the twofold higher rate of infant mortality experienced by African-American infants compared with w...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1994-10-01 00:00:00
abstract：:From 1967 to 1977, 72 patients with small cell carcinoma of the lung were seen. Thirty-five of these patients had unilaterally localized lesions (limited disease) and were treated with cobalt 60 radiation therapy (6,000 rad in six weeks) followed by chemotherapy consisting of cyclophosphamide (Cytoxan), vincristine, m...
journal_title：Journal of the National Medical Association
pub_type： 临床试验,杂志文章
doi：
更新日期：1986-03-01 00:00:00
abstract：:Two women over the age of 50 years presented with ketoacidosis as the first manifestation of diabetes mellitus. The first patient failed to respond to a regimen of hourly intramuscular injections of regular insulin. She only improved when a continuous intravenous infusion of regular insulin was utilized. The second pa...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1986-02-01 00:00:00
abstract：:The psychosomatic disorder termed Munchausen's syndrome has gained official recognition in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, in which it is referred to as a "chronic factitious disorder with physical symptoms." Sporadic case reports have been published over t...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1983-02-01 00:00:00
abstract：:It is believed that perioperative hemorrhage, in the hepatoportal area, results from a coagulopathy. This study determined if this could be quantitated by a modified recalcification time (MRT) test developed in our laboratory. Unlike prothrombin (PT) and activated partial thromboplastin times (APTT), the MRT is perfor...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1996-05-01 00:00:00
abstract：:A case of leukopenia associated with cimetidine therapy is reported. The patient had sarcoid cirrhosis with portal hypertension. Cimetidine therapy was instituted for upper gastrointestinal bleeding due to gastritis, resulted in leukopenia, and was reversed on discontinuation of therapy. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1980-08-01 00:00:00
abstract：:The three leukotriene (LT) modifiers approved for use in the United States, zileuton, zafirlukast, and montelukast, are the first new class of therapeutic agents to be introduced in 20 years for the treatment of asthma. These agents are referred to as leukotriene modifiers and have clearly demonstrated the ability to ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1999-08-01 00:00:00
abstract：:Paradoxical deterioration during antituberculous therapy is defined as the clinical or radiological worsening of pre-existing tuberculous lesions or the development of new lesions in a patient who initially improves. Although it has frequently been reported for patients infected with human immunodeficiency virus (HIV)...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-06-01 00:00:00
abstract：:A review of the literature on sickle cell trait was completed by Sears in 1978. Since that time, several papers have been published concerning the possible health risks of sickle cell trait. Data presented from these studies show that there is no association with sickle cell trait and overall survival, overall mortali...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1982-08-01 00:00:00
abstract：:There has been considerable discussion about translating science into practical messages, especially among urban minority and "hard-to-reach" populations. Unfortunately, many research findings rarely make it back in useful format to the general public. Few innovative techniques have been established that provide resea...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：BACKGROUND:Physician diversity is linked to improved quality of care of diverse patient populations. The transition from medical school to residency is an opportunity to improve and increase workforce diversity in all specialties. However, there is limited published literature on the factors contributing to the ranking...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2019.09.002
更新日期：2019-12-01 00:00:00
abstract：:During 2005, a risk assessment tool based on the Gail model was used to calculate the five-year risk of developing breast cancer for 445 women who live in socioeconomically disadvantaged urban communities in western Pennsylvania and who attended health fairs and other community-sponsored activities. This tool allowed ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-07-01 00:00:00
abstract：:In addition to well known parameters used for measuring in vitro cellular radiosensitivity (mean lethal dose, extrapolation number, quasithreshold dose), there are other, less well known measures that may be more important. The authors recently surveyed the literature and found that mean activation dose (D) has been n...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1989-07-01 00:00:00
abstract：:Hypertension is the leading cause of renal failure in this dialysis and transplant center. When malignant hypertension is encountered, the symptom complex of cachexia and failure to thrive highlights its clinical presentation. The courses of 32 black renal hypertensive patients studied retrospectively demonstrated thi...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1980-05-01 00:00:00
abstract：:A 64-year-old man got trismus and trigeminal neuralgia under the diagnosis of colon cancer with mandibular metastasis after emergency appendectomy and elective hemicolectomy. The patient chose to forgo further surgery and was given only palliative chemotherapy and radiotherapy. He died six months after diagnosis. Meta...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)31353-5
更新日期：2008-06-01 00:00:00
abstract：:The purpose of this study was to identify attitudes associated with the willingness of African Americans to participate in prostate cancer screening. Subjects > or = 40 years were recruited from South Central Los Angeles. Fifty-six respondents were divided into low or middle socioeconomic groups based on education and...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：BACKGROUND:Although there have been studies examining HIV knowledge among college population, current study is the first providing comparable information on HIV knowledge in general and testing specifically via online surveys among black and white college students. METHODS:Blacks (N=222) were recruited from 15 histori...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)31377-8
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:This study presents black-white breast cancer statistics, tumor histology and receptor status, and treatment patterns for all ages and by age groups (< 40, 40-49, and > or = 50). METHODS:The study used data from the National Cancer Institute (NCI) Surveillance, Epidemiology and End Results (SEER) program fo...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)31294-3
更新日期：2008-05-01 00:00:00
abstract：:A metabolic imbalance technique was used to study the effects of zinc deficiency on immunoglobulin levels in mice infected with Trypanosoma musculi or immunized with parasite products. Zinc-deficient mice developed higher numbers of parasitemia earlier and exhibited prolonged infection. Irrespective of the diet, highe...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：:Autosomal dominant polycystic kidney disease is one of the most common hereditary diseases, and frequently has well defined extrarenal manifestations. Very few cases of aortic aneurysms associated with this disorder are described in literature. We report a 42-year-old male with autosomal dominant polycystic kidney dis...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：2001-07-01 00:00:00
abstract：:Despite the widespread availability of firearms, stab wounds to the abdomen, back, and flank continue to account for a significant number of injuries. The proper sequencing of diagnostic modalities in this patient group is constantly undergoing change. We report our experience with these injuries and present a new alg...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：:Forty-two patients with renal cell carcinoma were evaluated with computerized tomography (CT) followed by surgical exploration, extirpative surgery, or autopsy to determine the accuracy of the CT scan in assessing the extension of the disease. There was an overall accuracy of 95 percent (40/42 patients). The two stagi...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1986-06-01 00:00:00
abstract：PURPOSE:This study aimed to evaluate whether comprehensive multidisciplinary care (cMDC) for breast cancer patients affected time from diagnosis to treatment, compliance with appointments and to assess for racial disparities. METHODS:This institutional review board approved retrospective study included adult patients ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2020.03.010
更新日期：2020-06-01 00:00:00
abstract：:Four hundred ninety-nine nosocomial infections (with 657 isolates) in 288 Surgical Service patients were monitored from February 1986 to June 1987 (17 months) to determine the influence that pathogen or site of infection had on the length of hospital stay. Patients with upper respiratory and skin infections were more ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
