Outpatient Fluoroquinolone Use in Children, 2000-2018.

abstract：:Pneumonia, most often caused by a respiratory virus, is common in childhood. Mycoplasma pneumoniae also is detected frequently, particularly in older children in the era of pneumococcal conjugate vaccination. Despite recommendations for β-lactam antibiotics, macrolide antibiotics, including erythromycin, clarithromyci...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Blyth CC,Gerber JS

更新日期：2018-02-19 00:00:00

abstract：Background:Trichosporonosis is an emerging and often fatal opportunistic fungal infection in immunocompromised patients, particularly those with hematologic malignancy, but data in children are lacking. Methods:We report here 3 cases of invasive infection caused by Trichosporon asahii in pediatric patients with acute ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Foster CE,Edwards MS,Brackett J,Schady DA,Healy CM,Baker CJ

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:Previous studies of cerebrospinal fluid (CSF) shunt infection treatment have been limited in size and unable to compare patient and treatment characteristics by infecting organism. Our objective was to describe variation in patient and treatment characteristics for children with first CSF shunt infection, st...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Simon TD,Kronman MP,Whitlock KB,Browd SR,Holubkov R,Kestle JRW,Kulkarni AV,Langley M,Limbrick DD,Luerssen TG,Oakes J,Riva-Cambrin J,Rozzelle C,Shannon CN,Tamber M,Wellons Iii JC,Whitehead WE,Mayer-Hamblett N,Hydroceph

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Invasive mold infections (IMIs) are a leading cause of mortality in immunocompromised children, yet there has never been an international epidemiologic investigation of pediatric IMIs. METHODS:This international, prospective cohort study was performed to characterize the epidemiology, antifungal therapy, an...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wattier RL,Dvorak CC,Hoffman JA,Brozovich AA,Bin-Hussain I,Groll AH,Castagnola E,Knapp KM,Zaoutis TE,Gustafsson B,Sung L,Berman D,Halasa NB,Abzug MJ,Velegraki A,Sharma TS,Fisher BT,Steinbach WJ

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Data on human immunodeficiency virus (HIV) and hepatitis B virus (HBV) and hepatitis C virus (HCV) coinfection among children in Africa are limited. We evaluated the seroprevalence of both viruses among healthy, HIV-uninfected children and HIV-infected children in the Kilimanjaro region of northern Tanzania....

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Muro FJ,Fiorillo SP,Sakasaka P,Odhiambo C,Reddy EA,Cunningham CK,Buchanan AM

更新日期：2013-12-01 00:00:00

abstract：:The Advisory Committee on Immunization Practices (ACIP) consists of medical and public health experts who develop recommendations on vaccine use in the United States. The ACIP meets 3 times per year, and members and Centers for Disease Control (CDC) staff present findings and discuss vaccine research, vaccine effectiv...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Schuster JE,O'Leary S,Kimberlin DW

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Cartridge-based nucleic acid amplification test (CB-NAAT) has been recommended for diagnosis of tuberculosis (TB) in children, but its wide use is limited by high cost and the need for well-equipped laboratories. This study was conducted in children with pulmonary TB to compare the diagnostic yield of TB-LAM...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Dayal R,Yadav A,Agarwal D,Kumar M,Kamal R,Singh D,Bhatnagar S

更新日期：2020-03-10 00:00:00

abstract：:Across 12 consecutive influenza seasons in Utah, medically-attended visits for laboratory-confirmed influenza infection peaked first among older children (12-18 years). Peak activity in older children preceded that of children 0-4 years by more than 2 days and that of peak activity among adults ≥65 years by more than ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Stockmann C,Pavia AT,Hersh AL,Spigarelli MG,Castle B,Korgenski K,Byington CL,Ampofo K

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Enteroviruses (EVs) occur frequently worldwide and are known to be associated with a broad spectrum of clinical manifestations from mild syndromes to neurological disease. To understand the epidemiology of EV in Korea, we characterized EV-infected cases during 2012-2019 based on national surveillance. METHO...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Kang HJ,Yoon Y,Lee YP,Kim HJ,Lee DY,Lee JW,Hyeon JY,Yoo JS,Lee S,Kang C,Choi W,Han MG

更新日期：2020-11-05 00:00:00

abstract：BACKGROUND:The objective was to describe respiratory syncytial virus (RSV) hospitalizations in Alberta, Canada over a 13-year period with an emphasis on the incidence and risk factors for repeat hospitalizations attributable to new RSV infections. METHODS:This was a retrospective database analysis. The Alberta Health ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wong K,Robinson JL,Hawkes MT

更新日期：2020-07-24 00:00:00

abstract：BACKGROUND:Acute gastroenteritis (AGE) in hematopoietic cell transplant (HCT) patients causes significant morbidity and mortality. Data regarding the longitudinal assessment of infectious pathogens during symptomatic AGE and asymptomatic periods, particularly in children, are limited. We investigated the prevalence of ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Schuster JE,Johnston SH,Piya B,Dulek DE,Wikswo ME,McHenry R,Browne H,Gautam R,Bowen MD,Vinjé J,Payne DC,Azimi P,Selvarangan R,Halasa N,Englund JA

更新日期：2020-09-17 00:00:00

abstract：BACKGROUND:Endothelial activation may contribute to development of severe disease from Plasmodium falciparum infection, but optimal markers of endothelial activation in severe malaria, the extent of endothelial activation in asymptomatic infection, and the effect of blood group O on endothelial activation have not been...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Park GS,Ireland KF,Opoka RO,John CC

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Respiratory viruses cause significant morbidity and death in infants; 99% of such deaths occur in resource-limited settings. Risk factors for initial and repeated respiratory viral infections in young infants in resource-limited settings have not been well described. METHODS:From 2011 to 2014, a birth cohor...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Boonyaratanakornkit J,Englund JA,Magaret AS,Bu Y,Tielsch JM,Khatry SK,Katz J,Kuypers J,Shrestha L,LeClerq SC,Steinhoff MC,Chu HY

更新日期：2020-02-28 00:00:00

abstract：:The Clinical Trials Transformation Initiative convened with several groups in the pediatric antibacterial drug development community with the goal of identifying challenges and recommending ways to improve current practice. Attention to 5 major areas hold the promise of making new antibiotics available for use in chil...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Noel GJ,Nambiar S,Bradley J,Clinical Trials Transformation Initiative’s Pediatric Antibiotic Drug Development Program.

更新日期：2019-03-28 00:00:00

abstract：BACKGROUND:The 2017-2018 influenza season was of high severity. Circulating influenza strains change periodically, making it important to determine vaccine effectiveness on an annual basis, especially for susceptible populations. The primary aim of our study was to estimate the effectiveness of the influenza vaccine am...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Powell LN,Bégué RE

更新日期：2020-09-17 00:00:00

abstract：Background:Children undergoing CIC frequently have positive urine culture results and receive many antimicrobial agents. Subsequently, this population is at high risk for infections caused by antimicrobial-resistant bacteria. Resistant pathogens, such as vancomycin-resistant Enterococcus (VRE), carbapenem-resistant Ent...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Forster CS,Courter J,Jackson EC,Mortensen JE,Haslam DB

更新日期：2017-11-24 00:00:00

abstract：OF KEY POINTS:Although relatively rare, invasive meningococcal disease continues to be a health concern, especially in young children. This systematic review clearly delineates both the near- and long-term morbidities that can occur after, and persist beyond, the period of acute illness. BACKGROUND:Although rare, inva...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Strifler L,Morris SK,Dang V,Tu HA,Minhas RS,Jamieson FB,Deeks SL,Crowcroft NS,Sander B

更新日期：2016-12-01 00:00:00

abstract：:Children presenting to an emergency department following an animal bite were found to be at risk for infection if they had puncture wounds, crush wounds, or were bitten by a cat. Of the infected wounds that were cultured, methicillin-resistant Staphylococcus aureus was not isolated as a pathogen. ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Ogden RK Jr,Hedican EB,Stach LM,Herigon JC,Jackson MA,Newland JG

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Shiga toxin (Stx)-producing Escherichia coli (STECs) are the most common cause of acute renal failure in children. The present study evaluated a 10-year STEC polymerase chain reaction screening regimen in children. METHODS:All routine stool culture specimens from patients below 10 years of age (n = 10 342) ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Matussek A,Einemo IM,Jogenfors A,Löfdahl S,Löfgren S

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The transmission of human immunodeficiency virus (HIV) among youth through high-risk behaviors continues to increase. Retention in Care is associated with positive clinical outcomes and a decrease in HIV transmission risk behaviors. We evaluated the clinical and demographic characteristics of non-perinatally...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Farmer C,Yehia BR,Fleishman JA,Rutstein R,Mathews WC,Nijhawan A,Moore RD,Gebo KA,Agwu AL,HIV Research Network.

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Septic arthritis is a serious infection, but the results of blood and joint fluid cultures are often negative in children. We describe here the clinical features and management of culture-negative septic arthritis in children at our hospital and their outcomes. METHODS:We performed a retrospective review of...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Spyridakis E,Gerber JS,Schriver E,Grundmeier RW,Porsch EA,St Geme JW,Downes KJ

更新日期：2019-07-01 00:00:00

abstract：:Although cryptococcal meningitis is uncommon in children and rare in neonates, it does occur. We highlight circumstances in which the diagnosis should be considered and methods required to confirm the diagnosis in young patients. ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Soni ZJ,Reubenson G,De Maayer T,Coovadia A,Lazarus EM

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Egypt has the highest prevalence of hepatitis C virus (HCV) infection. Anti-HCV antibodies were detectable in 3% of children in Upper Egypt. Our aim was to evaluate the efficacy of ledipasvir/sofosbuvir for chronic HCV genotype 4 in adolescents with/without hematological disorders and to determine the effect...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Makhlouf NA,Abdelmalek MO,Ibrahim ME,Abu-Faddan NH,Kheila AE,Mahmoud AA

更新日期：2020-02-15 00:00:00

abstract：BACKGROUND:In November 2020, the US Food and Drug Administration (FDA) provided Emergency Use Authorizations (EUA) for two novel virus-neutralizing monoclonal antibody therapies, bamlanivimab, and REGN-COV2 (casirivimab plus imdevimab), for the treatment of mild to moderate COVID-19 in adolescents and adults in specifi...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wolf J,Abzug MJ,Wattier RL,Sue PK,Vora SB,Zachariah P,Dulek DE,Waghmare A,Olivero R,Downes KJ,James SH,Pinninti SG,Yarbrough A,Aldrich ML,MacBrayne CE,Soma VL,Grapentine SP,Oliveira CR,Hayes M,Kimberlin DW,Jones S

更新日期：2021-01-03 00:00:00

abstract：BACKGROUND:Shigella is a leading cause of childhood diarrhea mortality in sub-Saharan Africa. Current World Health Organization guidelines recommend antibiotics for children in non cholera-endemic areas only in the presence of dysentery, a proxy for suspected Shigella infection. METHODS:To assess the sensitivity and s...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Pavlinac PB,Denno DM,John-Stewart GC,Onchiri FM,Naulikha JM,Odundo EA,Hulseberg CE,Singa BO,Manhart LE,Walson JL

更新日期：2016-12-01 00:00:00

abstract：Background:Solid organ transplant (SOT) recipients are at risk for invasive fungal disease (IFD). Data on IFD burden in pediatric patients are limited. We aimed to determine the incidence and outcome of IFD in a large cohort of pediatric patients who underwent SOT. Methods:A single-center cohort of pediatric patients ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Saxena S,Gee J,Klieger S,Kajon A,Petersen H,Zaoutis T,Fisher B

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:Prevention strategies for cytomegalovirus (CMV) in pediatric transplant recipients are sparsely reported. A hybrid strategy that combines prophylaxis with preemptive therapy using serial CMV viral load monitoring is an emerging option. We report our clinical outcomes with a hybrid strategy in pediatric heart...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Lin A,Worley S,Brubaker J,Boyle G,Nasman C,Sabella C,Danziger-Isakov LA

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Despite a high burden of staphylococcal skin disease in children and high incidence of Staphylococcus aureus bacteremia in adult Indigenous populations in northern Australia, there are few studies describing incidence or clinical information of invasive S aureus (ISA) infections in children. METHODS:We cond...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Engelman D,Hofer A,Davis JS,Carapetis JR,Baird RW,Giffard PM,Holt DC,Tong SY

更新日期：2014-12-01 00:00:00

abstract：:Considerable progress has been made in the prevention, diagnosis, and management of pediatric patients with invasive fungal disease (IFD). The reported decreasing trend in the incidence of invasive candidiasis (IC) over the past 15 years in both neonates and children has been encouraging. Nevertheless, due to the grow...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Pana ZD,Roilides E,Warris A,Groll AH,Zaoutis T

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:P1093 is an ongoing phase I/II multicenter open-label study of dolutegravir plus an optimized background regimen in age-defined pediatric cohorts; here we report the long-term safety and virologic efficacy outcomes for the oldest cohort. METHODS:The study enrolled human immunodeficiency virus type 1 (HIV-1)...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Viani RM,Ruel T,Alvero C,Fenton T,Acosta EP,Hazra R,Townley E,Palumbo P,Buchanan AM,Vavro C,Singh R,Graham B,Anthony P,George K,Wiznia A,P1093 Study Team .

更新日期：2020-04-30 00:00:00