Abstract:
:Although cryptococcal meningitis is uncommon in children and rare in neonates, it does occur. We highlight circumstances in which the diagnosis should be considered and methods required to confirm the diagnosis in young patients.
journal_name
J Pediatric Infect Dis Socjournal_title
Journal of the Pediatric Infectious Diseases Societyauthors
Soni ZJ,Reubenson G,De Maayer T,Coovadia A,Lazarus EMdoi
10.1093/jpids/pis037subject
Has Abstractpub_date
2012-09-01 00:00:00pages
250-3issue
3eissn
2048-7193issn
2048-7207pii
pis037journal_volume
1pub_type
杂志文章abstract::The Clinical Trials Transformation Initiative convened with several groups in the pediatric antibacterial drug development community with the goal of identifying challenges and recommending ways to improve current practice. Attention to 5 major areas hold the promise of making new antibiotics available for use in chil...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章,评审
doi:10.1093/jpids/piy001
更新日期:2019-03-28 00:00:00
abstract:BACKGROUND:The genetic makeup of circulating Staphylococcus aureus (SA) populations varies by region. The extent to which SA virulence determinants contribute to the severity of pediatric infections is poorly understood. The study objective was to describe the genetic population of invasive SA (ISA) isolates from child...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/pis087
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Septic arthritis is a serious infection, but the results of blood and joint fluid cultures are often negative in children. We describe here the clinical features and management of culture-negative septic arthritis in children at our hospital and their outcomes. METHODS:We performed a retrospective review of...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piy034
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Our goal was to characterize the epidemiology and clinical significance of congenital Zika virus (ZIKV) exposure by prospectively following a cohort of infants with possible congenital exposure through their first year of life. METHODS:We included infants born in New York City between 2016 and 2017 who had ...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piz027
更新日期:2020-07-13 00:00:00
abstract:BACKGROUND:Rotavirus is the most common cause of infectious diarrhea in children worldwide. Recent studies have described changes in the burden of all-cause gastroenteritis; however, there are limited data on the clinical and economic impact of rotavirus vaccine on cases of laboratory-confirmed rotavirus disease. METH...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/pis058
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Although long treatment courses of outpatient antimicrobials are often used in pediatric patients, few data exist regarding the frequency of adverse events (AEs) associated with these medications. METHODS:We performed a retrospective cohort study of all patients seen in the Infectious Diseases clinic at a t...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piu037
更新日期:2015-06-01 00:00:00
abstract:Background:Pseudomonas aeruginosa is a common cause of healthcare-associated infection. Multidrug-resistant (MDR) (>3 classes) and carbapenem-resistant (CR) P aeruginosa are significant threats globally. We used a large reference-laboratory database to study the epidemiology of P aeruginosa in children in the United St...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piw064
更新日期:2017-11-24 00:00:00
abstract::We conducted a survey of pediatric members of the Emerging Infections Network regarding outpatient parenteral antimicrobial therapy (OPAT) practices and clinical decision making about OPAT initiation. We identified substantial variation in characteristics and resources of pediatric OPAT practices. Opportunities to imp...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/pis137
更新日期:2014-03-01 00:00:00
abstract::Chronic granulomatous disease (CGD) is a congenital disorder characterized by recurrent life-threatening bacterial and fungal infections and development of severe inflammation secondary to a congenital defect in 1 of the 5 phagocyte oxidase (phox) subunits of the nicotinamide adenine dinucleotide phosphate (NADPH) oxi...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章,评审
doi:10.1093/jpids/piy015
更新日期:2018-05-09 00:00:00
abstract::Coronaviruses contribute to the burden of respiratory diseases in children, frequently manifesting in upper respiratory symptoms considered to be part of the "common cold." Recent epidemics of novel coronaviruses recognized in the 21st century have highlighted issues of zoonotic origins of transmissible respiratory vi...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章,评审
doi:10.1093/jpids/piaa037
更新日期:2020-04-30 00:00:00
abstract:BACKGROUND:Egypt has the highest prevalence of hepatitis C virus (HCV) infection. Anti-HCV antibodies were detectable in 3% of children in Upper Egypt. Our aim was to evaluate the efficacy of ledipasvir/sofosbuvir for chronic HCV genotype 4 in adolescents with/without hematological disorders and to determine the effect...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piaa006
更新日期:2020-02-15 00:00:00
abstract::Among 66 antiretroviral-naive children aged <3 years with human immunodeficiency virus (HIV) or coinfected with HIV and tuberculosis and initiating efavirenz-based antiretroviral therapy (ART), non-nucleoside reverse transcriptase inhibitor (NNRTI) resistance was detected before ART in 5 (7.6%). Virologic failure occu...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piz038
更新日期:2020-04-30 00:00:00
abstract:Introduction:Antimicrobial use is decreasing across freestanding children's hospitals, predominantly in institutions with antimicrobial stewardship programs (ASPs) in place. A highly effective ASP should effect a greater decrease in use than predicted by existing trends. Antimicrobial stewardship programs depend on cli...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piw054
更新日期:2017-11-24 00:00:00
abstract:BACKGROUND:Single-nucleotide polymorphisms (SNPs) in the fucosyltransferase genes FUT2 and FUT3 have been associated with susceptibility to various infectious and inflammatory disorders. FUT variations influence the expression of human histo-blood group antigens (HBGAs) (H-type 1 and Lewis), which are highly expressed ...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piy085
更新日期:2019-12-27 00:00:00
abstract::Children with healthcare-associated Clostridium difficile infection were identified. The incidence increased from 3.2/10,000 patient days in 2007 to 5.2/10,000 patient days in 2011 (p < 0.001). Of 169 isolates, the most common North American Pulsed-Field (NAP) types were NAP4 (n = 43; (25.4%), and NAP1 (n = 25;14.8%) ...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piv011
更新日期:2015-12-01 00:00:00
abstract:OF KEY POINTS:Although relatively rare, invasive meningococcal disease continues to be a health concern, especially in young children. This systematic review clearly delineates both the near- and long-term morbidities that can occur after, and persist beyond, the period of acute illness. BACKGROUND:Although rare, inva...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章,评审
doi:10.1093/jpids/piv065
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Shiga toxin (Stx)-producing Escherichia coli (STECs) are the most common cause of acute renal failure in children. The present study evaluated a 10-year STEC polymerase chain reaction screening regimen in children. METHODS:All routine stool culture specimens from patients below 10 years of age (n = 10 342) ...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piv003
更新日期:2016-06-01 00:00:00
abstract::We studied the effect of azithromycin (AZM) on macrophage responses to pneumococci. We found that exposure of pneumococci to AZM led to reduced tumor necrosis factor (TNF) secretion by macrophages; this effect was observed in response to both AZM-susceptible and AZM-resistant (AZM-R) pneumococci. ...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/pit014
更新日期:2014-06-01 00:00:00
abstract::Considerable progress has been made in the prevention, diagnosis, and management of pediatric patients with invasive fungal disease (IFD). The reported decreasing trend in the incidence of invasive candidiasis (IC) over the past 15 years in both neonates and children has been encouraging. Nevertheless, due to the grow...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章,评审
doi:10.1093/jpids/pix046
更新日期:2017-09-01 00:00:00
abstract::The reduction in human immunodeficiency virus (HIV) transmission through breastmilk with maternal combination antiretroviral therapy (cART) has led many pregnant women living with HIV and healthcare providers to question exclusive formula feeding in resource-rich settings. Here, we describe cART prophylaxis in 3 breas...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piz003
更新日期:2020-04-30 00:00:00
abstract:BACKGROUND:This study was designed to determine whether an automated hospital-based influenza vaccination screening program leveraging the electronic medical record (EMR) increases vaccination rates. METHODS:We performed a retrospective cohort study of all children ≥6 months old admitted to medical, surgical, rehabili...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/pit044
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:In November 2020, the US Food and Drug Administration (FDA) provided Emergency Use Authorizations (EUA) for two novel virus-neutralizing monoclonal antibody therapies, bamlanivimab, and REGN-COV2 (casirivimab plus imdevimab), for the treatment of mild to moderate COVID-19 in adolescents and adults in specifi...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piaa175
更新日期:2021-01-03 00:00:00
abstract::Little information on the efficacy and pharmacokinetics of letermovir among immunocompromised children is currently available. We describe here the use of letermovir in a 2-year-old immunocompromised child with ganciclovir-resistant cytomegalovirus disease who required extracorporeal membrane oxygenation. Detailed inf...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piz033
更新日期:2020-02-28 00:00:00
abstract:BACKGROUND:Enteroviruses (EVs) occur frequently worldwide and are known to be associated with a broad spectrum of clinical manifestations from mild syndromes to neurological disease. To understand the epidemiology of EV in Korea, we characterized EV-infected cases during 2012-2019 based on national surveillance. METHO...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piaa111
更新日期:2020-11-05 00:00:00
abstract::Frontline clinicians caring for hospitalized children typically knew the indication for antimicrobial therapy but less often knew the current day or planned duration of therapy or of plans for intravenous to oral conversion. Night shift clinicians were less likely to know day of therapy and duration of therapy than da...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piv026
更新日期:2016-12-01 00:00:00
abstract::Recent guidelines recommend empiric vancomycin dosing of 60 mg/kg per day and consideration of higher trough concentrations (15-20 mcg/mL) in children with invasive infections. In this study, we report a retrospective review evaluating the dose/trough relationship and predicted area under the curve in pediatric patien...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/pis083
更新日期:2013-09-01 00:00:00
abstract::Among newborns with congenital cytomegalovirus (CMV) infection from China, there was no difference in CMV viral load in saliva specimens dried and stored at room temperature compared with those kept wet and stored cold, even after longer storage time for the former than the later (74 vs 58 days, P = .02). ...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piy048
更新日期:2018-08-17 00:00:00
abstract:BACKGROUND:Previous studies of cerebrospinal fluid (CSF) shunt infection treatment have been limited in size and unable to compare patient and treatment characteristics by infecting organism. Our objective was to describe variation in patient and treatment characteristics for children with first CSF shunt infection, st...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piy035
更新日期:2019-07-01 00:00:00
abstract::Pythium insidiosum, also known as "swamp cancer," has been long known for its destructive effects on plants and animals. Infections with this fungus-like organism typically occur in temperate, tropical, and subtropical regions [ 1]. Human infection with P insidiosum, although exceedingly rare, is characterized by inva...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/piu015
更新日期:2015-03-01 00:00:00
abstract::We determined the rates of community-acquired pneumonia (CAP)-associated hospitalizations and complications in Athens, over a period covering 4 years before and 4 years after the implementation of the 7-valent pneumococcal vaccine (PCV7) in Greece. PCV7 had no impact on pediatric CAP rates, whereas there was an increa...
journal_title:Journal of the Pediatric Infectious Diseases Society
pub_type: 杂志文章
doi:10.1093/jpids/pit088
更新日期:2015-09-01 00:00:00