Update From the Advisory Committee on Immunization Practices.

abstract：:We studied the effect of azithromycin (AZM) on macrophage responses to pneumococci. We found that exposure of pneumococci to AZM led to reduced tumor necrosis factor (TNF) secretion by macrophages; this effect was observed in response to both AZM-susceptible and AZM-resistant (AZM-R) pneumococci. ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Ingram K,Marker M,Meals E,Talati AJ,Spentzas T,English BK

更新日期：2014-06-01 00:00:00

abstract：Background:Pertussis is an important cause of hospitalization and death in infants too young to be vaccinated (aged <2 months). Limited data on infant pertussis have been reported from Central America. The aim of this study was to characterize acute respiratory illnesses (ARIs) attributable to Bordetella pertussis amon...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Phadke VK,McCracken JP,Kriss JL,Lopez MR,Lindblade KA,Bryan JP,Garcia ME,Funes CE,Omer SB

更新日期：2018-12-03 00:00:00

abstract：BACKGROUND:Parechovirus A (PeV-A) is an important cause of sepsis and meningoencephalitis in neonates and young infants. Thus, identifying the source of PeV-A is essential for prevention; however, little is known regarding the spread of PeV-A among family members of PeV-A-infected neonates and young infants. METHODS:I...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Izumita R,Deuchi K,Aizawa Y,Habuka R,Watanabe K,Otsuka T,Saitoh A

更新日期：2019-12-27 00:00:00

abstract：:Children with healthcare-associated Clostridium difficile infection were identified. The incidence increased from 3.2/10,000 patient days in 2007 to 5.2/10,000 patient days in 2011 (p < 0.001). Of 169 isolates, the most common North American Pulsed-Field (NAP) types were NAP4 (n = 43; (25.4%), and NAP1 (n = 25;14.8%) ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Le Saux N,Gravel D,Mulvey M,Moore D,Langley JM,Richardson S,Quach C,Choi KB,Miller M,Katz K,Canadian Nosocomial Infection Surveillance Program.

更新日期：2015-12-01 00:00:00

abstract：Background:Data on long-term toxicity of antiretroviral therapy (ART) in HIV-infected children are sparse. PENPACT-1 was an open-label trial in which HIV-infected children were assigned randomly to receive protease inhibitor (PI)- or nonnucleoside reverse-transcriptase inhibitor (NNRTI)-based ART. Methods:We examined ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Melvin AJ,Warshaw M,Compagnucci A,Saidi Y,Harrison L,Turkova A,Tudor-Williams G,PENPACT-1 (PENTA 9\/PACTG 390\/ANRS 103) Study Team.

更新日期：2017-09-01 00:00:00

abstract：Introduction:Antimicrobial use is decreasing across freestanding children's hospitals, predominantly in institutions with antimicrobial stewardship programs (ASPs) in place. A highly effective ASP should effect a greater decrease in use than predicted by existing trends. Antimicrobial stewardship programs depend on cli...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Willis ZI,Gillon J,Xu M,Slaughter JC,Di Pentima MC

更新日期：2017-11-24 00:00:00

abstract：:Coronaviruses contribute to the burden of respiratory diseases in children, frequently manifesting in upper respiratory symptoms considered to be part of the "common cold." Recent epidemics of novel coronaviruses recognized in the 21st century have highlighted issues of zoonotic origins of transmissible respiratory vi...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Ogimi C,Kim YJ,Martin ET,Huh HJ,Chiu CH,Englund JA

更新日期：2020-04-30 00:00:00

abstract：:Recent guidelines recommend empiric vancomycin dosing of 60 mg/kg per day and consideration of higher trough concentrations (15-20 mcg/mL) in children with invasive infections. In this study, we report a retrospective review evaluating the dose/trough relationship and predicted area under the curve in pediatric patien...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Chhim RF,Arnold SR,Lee KR

更新日期：2013-09-01 00:00:00

abstract：Background:Evaluation for neonatal sepsis routinely includes performing both aerobic and anaerobic blood cultures despite our lack of knowledge of the true incidence of anaerobic bacteremia in this age group and the consequences of not performing these paired cultures. Methods:We performed a retrospective review of al...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Messbarger N,Neemann K

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:The 2017-2018 influenza season was of high severity. Circulating influenza strains change periodically, making it important to determine vaccine effectiveness on an annual basis, especially for susceptible populations. The primary aim of our study was to estimate the effectiveness of the influenza vaccine am...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Powell LN,Bégué RE

更新日期：2020-09-17 00:00:00

abstract：Background:Children undergoing CIC frequently have positive urine culture results and receive many antimicrobial agents. Subsequently, this population is at high risk for infections caused by antimicrobial-resistant bacteria. Resistant pathogens, such as vancomycin-resistant Enterococcus (VRE), carbapenem-resistant Ent...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Forster CS,Courter J,Jackson EC,Mortensen JE,Haslam DB

更新日期：2017-11-24 00:00:00

abstract：:We conducted a survey of pediatric members of the Emerging Infections Network regarding outpatient parenteral antimicrobial therapy (OPAT) practices and clinical decision making about OPAT initiation. We identified substantial variation in characteristics and resources of pediatric OPAT practices. Opportunities to imp...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Banerjee R,Beekmann SE,Doby EH,Polgreen PM,Rathore MH,Hersh AL

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Data on human immunodeficiency virus (HIV) and hepatitis B virus (HBV) and hepatitis C virus (HCV) coinfection among children in Africa are limited. We evaluated the seroprevalence of both viruses among healthy, HIV-uninfected children and HIV-infected children in the Kilimanjaro region of northern Tanzania....

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Muro FJ,Fiorillo SP,Sakasaka P,Odhiambo C,Reddy EA,Cunningham CK,Buchanan AM

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The clinical and economic outcomes associated with pediatric antimicrobial stewardship programs (ASPs) and other supplemental antimicrobial stewardship (AS) interventions have not been well described or reviewed. METHODS:We performed a systematic review using PubMed to identify studies with any of the follo...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Smith MJ,Gerber JS,Hersh AL

更新日期：2015-12-01 00:00:00

abstract：:Frontline clinicians caring for hospitalized children typically knew the indication for antimicrobial therapy but less often knew the current day or planned duration of therapy or of plans for intravenous to oral conversion. Night shift clinicians were less likely to know day of therapy and duration of therapy than da...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Larru B,Sulieman SE,Localio R,Ross RK,Sharland M,Zaoutis TE,Gerber JS

更新日期：2016-12-01 00:00:00

abstract：:We report here 18 cases of pediatric group A streptococcal toxic shock syndrome, associated clinical findings, and bacterial molecular genetic characteristics discovered through whole-genome sequencing. This comparative whole-genome sequencing revealed unique gene content (speK) and polymorphisms (dpiB) in emm87 group...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Deniskin R,Shah B,Muñoz FM,Flores AR

更新日期：2019-07-01 00:00:00

abstract：:We examined the uptake of rotavirus vaccine and compared trends in acute gastroenteritis (AGE)-associated hospitalizations and outpatient visits among American Indian and Alaska Native (AI/AN) children aged <5 years before and after introduction of the rotavirus vaccine. The rates of AGE-associated hospitalization and...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Grytdal SP,Haberling DL,Kennedy JL,McCollum JT,Parashar UD

更新日期：2018-05-15 00:00:00

abstract：BACKGROUND:A moderate to severe (M/S) influenza clinical endpoint has been proposed in children, defined as fever >39°C, otitis media, lower respiratory tract infection, or serious extrapulmonary manifestations. The objective of the study was to evaluate the M/S measure against clinically relevant outcomes including ho...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Rao S,Yanni E,Moss A,Lamb MM,Schuind A,Bekkat-Berkani R,Innis BL,Cotter J,Mistry RD,Asturias EJ

更新日期：2020-09-17 00:00:00

abstract：Background:Lower procalcitonin (PCT) concentrations are associated with reduced risk of bacterial community-acquired pneumonia (CAP) in adults, but data in children are limited. Methods:We analyzed serum PCT concentrations from children hospitalized with radiographically confirmed CAP enrolled in the Centers for Disea...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Stockmann C,Ampofo K,Killpack J,Williams DJ,Edwards KM,Grijalva CG,Arnold SR,McCullers JA,Anderson EJ,Wunderink RG,Self WH,Bramley A,Jain S,Pavia AT,Blaschke AJ

更新日期：2018-02-19 00:00:00

abstract：BACKGROUND:Despite successes in lung transplantation, with infection as the leading cause of death in the first year following lung transplantation, there remains a lag in survival compared with other solid organ transplants. Infections that occur early after transplantation may impact short- and long-term outcomes in ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Onyearugbulem C,Coss-Bu J,Gazzaneo MC,Melicoff E,Das S,Lam F,Mallory GB,Munoz FM

更新日期：2020-06-13 00:00:00

abstract：Background:Solid organ transplant (SOT) recipients are at risk for invasive fungal disease (IFD). Data on IFD burden in pediatric patients are limited. We aimed to determine the incidence and outcome of IFD in a large cohort of pediatric patients who underwent SOT. Methods:A single-center cohort of pediatric patients ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Saxena S,Gee J,Klieger S,Kajon A,Petersen H,Zaoutis T,Fisher B

更新日期：2018-08-17 00:00:00

abstract：:Coronavirus disease (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Physicians in China reported what is believed to be the first adult case of a SARS-CoV-2 infection associated with acute Guillain-Barré syndrome (GBS), followed by 5 adult Italian patients and anoth...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Khalifa M,Zakaria F,Ragab Y,Saad A,Bamaga A,Emad Y,Rasker JJ

更新日期：2020-09-17 00:00:00

abstract：BACKGROUND:Endothelial activation may contribute to development of severe disease from Plasmodium falciparum infection, but optimal markers of endothelial activation in severe malaria, the extent of endothelial activation in asymptomatic infection, and the effect of blood group O on endothelial activation have not been...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Park GS,Ireland KF,Opoka RO,John CC

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The transmission of human immunodeficiency virus (HIV) among youth through high-risk behaviors continues to increase. Retention in Care is associated with positive clinical outcomes and a decrease in HIV transmission risk behaviors. We evaluated the clinical and demographic characteristics of non-perinatally...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Farmer C,Yehia BR,Fleishman JA,Rutstein R,Mathews WC,Nijhawan A,Moore RD,Gebo KA,Agwu AL,HIV Research Network.

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Although long treatment courses of outpatient antimicrobials are often used in pediatric patients, few data exist regarding the frequency of adverse events (AEs) associated with these medications. METHODS:We performed a retrospective cohort study of all patients seen in the Infectious Diseases clinic at a t...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Olson SC,Smith S,Weissman SJ,Kronman MP

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The objective was to describe respiratory syncytial virus (RSV) hospitalizations in Alberta, Canada over a 13-year period with an emphasis on the incidence and risk factors for repeat hospitalizations attributable to new RSV infections. METHODS:This was a retrospective database analysis. The Alberta Health ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wong K,Robinson JL,Hawkes MT

更新日期：2020-07-24 00:00:00

abstract：BACKGROUND:Parainfluenza virus (PIV), a common pediatric pathogen, is associated with significant morbidity in immunocompromised (IC) hosts. DAS181, a novel sialidase fusion protein inhibitor, seems to be effective against PIV in vitro and in vivo; its use in IC children has not been evaluated. METHODS:Patients were d...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Waghmare A,Wagner T,Andrews R,Smith S,Kuypers J,Boeckh M,Moss R,Englund JA

更新日期：2015-06-01 00:00:00

abstract：OF KEY POINTS:Although relatively rare, invasive meningococcal disease continues to be a health concern, especially in young children. This systematic review clearly delineates both the near- and long-term morbidities that can occur after, and persist beyond, the period of acute illness. BACKGROUND:Although rare, inva...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Strifler L,Morris SK,Dang V,Tu HA,Minhas RS,Jamieson FB,Deeks SL,Crowcroft NS,Sander B

更新日期：2016-12-01 00:00:00

abstract：:Actinomycetes are Gram-positive bacteria that can be part of the normal human flora of the gastrointestinal, pulmonary, and genital tract. Infections are rare, slowly progressing and most commonly affect the cervicofacial region. Actinomyces israelii is the most frequently isolated species but a number of other specie...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Walther K,Bruder E,Goldenberger D,Mayr J,Schaad UB,Ritz N

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:In November 2020, the US Food and Drug Administration (FDA) provided Emergency Use Authorizations (EUA) for two novel virus-neutralizing monoclonal antibody therapies, bamlanivimab, and REGN-COV2 (casirivimab plus imdevimab), for the treatment of mild to moderate COVID-19 in adolescents and adults in specifi...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wolf J,Abzug MJ,Wattier RL,Sue PK,Vora SB,Zachariah P,Dulek DE,Waghmare A,Olivero R,Downes KJ,James SH,Pinninti SG,Yarbrough A,Aldrich ML,MacBrayne CE,Soma VL,Grapentine SP,Oliveira CR,Hayes M,Kimberlin DW,Jones S

更新日期：2021-01-03 00:00:00