Frontline Clinician Knowledge of Antimicrobial Prescribing in an Academic Tertiary Children's Hospital: A Point Prevalence Study.

abstract：:We performed a seroepidemiologic study of sera from children in Brooklyn, New York, before and after the implementation of prenatal chlamydial screening almost 20% of children aged ≤10 years in the prescreening group had anti-Chlamydia trachomatis immunoglobulin G compared with none in the postscreening group. ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Banniettis N,Wisecup K,Boland L,Watanabe I,Hammerschlag MR,Kohlhoff S

更新日期：2020-01-20 00:00:00

abstract：OF KEY POINTS:Although relatively rare, invasive meningococcal disease continues to be a health concern, especially in young children. This systematic review clearly delineates both the near- and long-term morbidities that can occur after, and persist beyond, the period of acute illness. BACKGROUND:Although rare, inva...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Strifler L,Morris SK,Dang V,Tu HA,Minhas RS,Jamieson FB,Deeks SL,Crowcroft NS,Sander B

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:P1093 is an ongoing phase I/II multicenter open-label study of dolutegravir plus an optimized background regimen in age-defined pediatric cohorts; here we report the long-term safety and virologic efficacy outcomes for the oldest cohort. METHODS:The study enrolled human immunodeficiency virus type 1 (HIV-1)...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Viani RM,Ruel T,Alvero C,Fenton T,Acosta EP,Hazra R,Townley E,Palumbo P,Buchanan AM,Vavro C,Singh R,Graham B,Anthony P,George K,Wiznia A,P1093 Study Team .

更新日期：2020-04-30 00:00:00

abstract：BACKGROUND:The 2017-2018 influenza season was of high severity. Circulating influenza strains change periodically, making it important to determine vaccine effectiveness on an annual basis, especially for susceptible populations. The primary aim of our study was to estimate the effectiveness of the influenza vaccine am...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Powell LN,Bégué RE

更新日期：2020-09-17 00:00:00

abstract：Background:Evaluation for neonatal sepsis routinely includes performing both aerobic and anaerobic blood cultures despite our lack of knowledge of the true incidence of anaerobic bacteremia in this age group and the consequences of not performing these paired cultures. Methods:We performed a retrospective review of al...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Messbarger N,Neemann K

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:Previous studies of cerebrospinal fluid (CSF) shunt infection treatment have been limited in size and unable to compare patient and treatment characteristics by infecting organism. Our objective was to describe variation in patient and treatment characteristics for children with first CSF shunt infection, st...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Simon TD,Kronman MP,Whitlock KB,Browd SR,Holubkov R,Kestle JRW,Kulkarni AV,Langley M,Limbrick DD,Luerssen TG,Oakes J,Riva-Cambrin J,Rozzelle C,Shannon CN,Tamber M,Wellons Iii JC,Whitehead WE,Mayer-Hamblett N,Hydroceph

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:A moderate to severe (M/S) influenza clinical endpoint has been proposed in children, defined as fever >39°C, otitis media, lower respiratory tract infection, or serious extrapulmonary manifestations. The objective of the study was to evaluate the M/S measure against clinically relevant outcomes including ho...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Rao S,Yanni E,Moss A,Lamb MM,Schuind A,Bekkat-Berkani R,Innis BL,Cotter J,Mistry RD,Asturias EJ

更新日期：2020-09-17 00:00:00

abstract：BACKGROUND:In theory, active surveillance of methicillin-resistant Staphylococcus aureus (MRSA) reduces MRSA spread by identifying all MRSA-colonized patients and placing them under contact precautions. In October 2007, Illinois mandated active MRSA surveillance in all intensive care units, including neonatal intensive...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Lyles RD,Trick WE,Hayden MK,Lolans K,Fogg L,Logan LK,Shulman ST,Weinstein RA,Lin MY,Centers for Disease Control and Prevention, Prevention Epicenters Program.

更新日期：2016-12-01 00:00:00

abstract：:We report a case of disseminated tularemia in a previously healthy 8-month-old male. This case highlights an atypical presentation of tularemia with multisystem organ involvement. The diagnosis was complicated by concurrent primary cytomegalovirus infection. Bronchoalveolar lavage culture confirmed the diagnosis. The ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Stringham S,Green Hines A,Attebery J,Darwin L,Wachholtz A,Deschamp A,Choudhry O,Neemann K

更新日期：2020-06-14 00:00:00

abstract：BACKGROUND:Cartridge-based nucleic acid amplification test (CB-NAAT) has been recommended for diagnosis of tuberculosis (TB) in children, but its wide use is limited by high cost and the need for well-equipped laboratories. This study was conducted in children with pulmonary TB to compare the diagnostic yield of TB-LAM...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Dayal R,Yadav A,Agarwal D,Kumar M,Kamal R,Singh D,Bhatnagar S

更新日期：2020-03-10 00:00:00

abstract：:We conducted a survey of pediatric members of the Emerging Infections Network regarding outpatient parenteral antimicrobial therapy (OPAT) practices and clinical decision making about OPAT initiation. We identified substantial variation in characteristics and resources of pediatric OPAT practices. Opportunities to imp...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Banerjee R,Beekmann SE,Doby EH,Polgreen PM,Rathore MH,Hersh AL

更新日期：2014-03-01 00:00:00

abstract：:Coronaviruses contribute to the burden of respiratory diseases in children, frequently manifesting in upper respiratory symptoms considered to be part of the "common cold." Recent epidemics of novel coronaviruses recognized in the 21st century have highlighted issues of zoonotic origins of transmissible respiratory vi...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Ogimi C,Kim YJ,Martin ET,Huh HJ,Chiu CH,Englund JA

更新日期：2020-04-30 00:00:00

abstract：BACKGROUND:In November 2020, the US Food and Drug Administration (FDA) provided Emergency Use Authorizations (EUA) for two novel virus-neutralizing monoclonal antibody therapies, bamlanivimab, and REGN-COV2 (casirivimab plus imdevimab), for the treatment of mild to moderate COVID-19 in adolescents and adults in specifi...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wolf J,Abzug MJ,Wattier RL,Sue PK,Vora SB,Zachariah P,Dulek DE,Waghmare A,Olivero R,Downes KJ,James SH,Pinninti SG,Yarbrough A,Aldrich ML,MacBrayne CE,Soma VL,Grapentine SP,Oliveira CR,Hayes M,Kimberlin DW,Jones S

更新日期：2021-01-03 00:00:00

abstract：BACKGROUND:Invasive mold infections (IMIs) are a leading cause of mortality in immunocompromised children, yet there has never been an international epidemiologic investigation of pediatric IMIs. METHODS:This international, prospective cohort study was performed to characterize the epidemiology, antifungal therapy, an...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wattier RL,Dvorak CC,Hoffman JA,Brozovich AA,Bin-Hussain I,Groll AH,Castagnola E,Knapp KM,Zaoutis TE,Gustafsson B,Sung L,Berman D,Halasa NB,Abzug MJ,Velegraki A,Sharma TS,Fisher BT,Steinbach WJ

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Despite a high burden of staphylococcal skin disease in children and high incidence of Staphylococcus aureus bacteremia in adult Indigenous populations in northern Australia, there are few studies describing incidence or clinical information of invasive S aureus (ISA) infections in children. METHODS:We cond...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Engelman D,Hofer A,Davis JS,Carapetis JR,Baird RW,Giffard PM,Holt DC,Tong SY

更新日期：2014-12-01 00:00:00

abstract：Introduction:Antimicrobial use is decreasing across freestanding children's hospitals, predominantly in institutions with antimicrobial stewardship programs (ASPs) in place. A highly effective ASP should effect a greater decrease in use than predicted by existing trends. Antimicrobial stewardship programs depend on cli...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Willis ZI,Gillon J,Xu M,Slaughter JC,Di Pentima MC

更新日期：2017-11-24 00:00:00

abstract：:We examined the uptake of rotavirus vaccine and compared trends in acute gastroenteritis (AGE)-associated hospitalizations and outpatient visits among American Indian and Alaska Native (AI/AN) children aged <5 years before and after introduction of the rotavirus vaccine. The rates of AGE-associated hospitalization and...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Grytdal SP,Haberling DL,Kennedy JL,McCollum JT,Parashar UD

更新日期：2018-05-15 00:00:00

abstract：BACKGROUND:Prevention strategies for cytomegalovirus (CMV) in pediatric transplant recipients are sparsely reported. A hybrid strategy that combines prophylaxis with preemptive therapy using serial CMV viral load monitoring is an emerging option. We report our clinical outcomes with a hybrid strategy in pediatric heart...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Lin A,Worley S,Brubaker J,Boyle G,Nasman C,Sabella C,Danziger-Isakov LA

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Scrub typhus, caused by Orientia tsutsugamushi, is a major cause of acute febrile illness in children in the rural tropics. METHODS:We recruited 60 febrile pediatric patients with a positive scrub typhus rapid diagnostic test result and 40 healthy controls from Chiang Rai Province in northern Thailand. Diag...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wangrangsimakul T,Greer RC,Chanta C,Nedsuwan S,Blacksell SD,Day NPJ,Paris DH

更新日期：2020-04-30 00:00:00

abstract：:Chronic granulomatous disease (CGD) is a congenital disorder characterized by recurrent life-threatening bacterial and fungal infections and development of severe inflammation secondary to a congenital defect in 1 of the 5 phagocyte oxidase (phox) subunits of the nicotinamide adenine dinucleotide phosphate (NADPH) oxi...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Connelly JA,Marsh R,Parikh S,Talano JA

更新日期：2018-05-09 00:00:00

abstract：:E-consults replace "curbside" interactions, facilitate provider-specialist communication, document within the medical record, and track relative value units (RVUs). Pediatric infectious diseases (PID) E-consults commonly relate to vaccines, exposures, diagnoses, and treatments. The documented RVU effort of 197 consecu...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Gonzalez BE,Sabella C,Esper FP,Daniels HL,Saracusa C,Boutros J,Foster CB

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Endothelial activation may contribute to development of severe disease from Plasmodium falciparum infection, but optimal markers of endothelial activation in severe malaria, the extent of endothelial activation in asymptomatic infection, and the effect of blood group O on endothelial activation have not been...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Park GS,Ireland KF,Opoka RO,John CC

更新日期：2012-03-01 00:00:00

abstract：:We report here 18 cases of pediatric group A streptococcal toxic shock syndrome, associated clinical findings, and bacterial molecular genetic characteristics discovered through whole-genome sequencing. This comparative whole-genome sequencing revealed unique gene content (speK) and polymorphisms (dpiB) in emm87 group...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Deniskin R,Shah B,Muñoz FM,Flores AR

更新日期：2019-07-01 00:00:00

abstract：:Children presenting to an emergency department following an animal bite were found to be at risk for infection if they had puncture wounds, crush wounds, or were bitten by a cat. Of the infected wounds that were cultured, methicillin-resistant Staphylococcus aureus was not isolated as a pathogen. ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Ogden RK Jr,Hedican EB,Stach LM,Herigon JC,Jackson MA,Newland JG

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Parainfluenza virus (PIV), a common pediatric pathogen, is associated with significant morbidity in immunocompromised (IC) hosts. DAS181, a novel sialidase fusion protein inhibitor, seems to be effective against PIV in vitro and in vivo; its use in IC children has not been evaluated. METHODS:Patients were d...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Waghmare A,Wagner T,Andrews R,Smith S,Kuypers J,Boeckh M,Moss R,Englund JA

更新日期：2015-06-01 00:00:00

abstract：Background:Data on long-term toxicity of antiretroviral therapy (ART) in HIV-infected children are sparse. PENPACT-1 was an open-label trial in which HIV-infected children were assigned randomly to receive protease inhibitor (PI)- or nonnucleoside reverse-transcriptase inhibitor (NNRTI)-based ART. Methods:We examined ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Melvin AJ,Warshaw M,Compagnucci A,Saidi Y,Harrison L,Turkova A,Tudor-Williams G,PENPACT-1 (PENTA 9\/PACTG 390\/ANRS 103) Study Team.

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Enteroviruses (EVs) occur frequently worldwide and are known to be associated with a broad spectrum of clinical manifestations from mild syndromes to neurological disease. To understand the epidemiology of EV in Korea, we characterized EV-infected cases during 2012-2019 based on national surveillance. METHO...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Kang HJ,Yoon Y,Lee YP,Kim HJ,Lee DY,Lee JW,Hyeon JY,Yoo JS,Lee S,Kang C,Choi W,Han MG

更新日期：2020-11-05 00:00:00

abstract：:Actinomycetes are Gram-positive bacteria that can be part of the normal human flora of the gastrointestinal, pulmonary, and genital tract. Infections are rare, slowly progressing and most commonly affect the cervicofacial region. Actinomyces israelii is the most frequently isolated species but a number of other specie...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Walther K,Bruder E,Goldenberger D,Mayr J,Schaad UB,Ritz N

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Parechovirus A (PeV-A) is an important cause of sepsis and meningoencephalitis in neonates and young infants. Thus, identifying the source of PeV-A is essential for prevention; however, little is known regarding the spread of PeV-A among family members of PeV-A-infected neonates and young infants. METHODS:I...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Izumita R,Deuchi K,Aizawa Y,Habuka R,Watanabe K,Otsuka T,Saitoh A

更新日期：2019-12-27 00:00:00

abstract：:Although cryptococcal meningitis is uncommon in children and rare in neonates, it does occur. We highlight circumstances in which the diagnosis should be considered and methods required to confirm the diagnosis in young patients. ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Soni ZJ,Reubenson G,De Maayer T,Coovadia A,Lazarus EM

更新日期：2012-09-01 00:00:00