Intrafamilial Transmission of Parechovirus A and Enteroviruses in Neonates and Young Infants.

abstract：BACKGROUND:Prevention strategies for cytomegalovirus (CMV) in pediatric transplant recipients are sparsely reported. A hybrid strategy that combines prophylaxis with preemptive therapy using serial CMV viral load monitoring is an emerging option. We report our clinical outcomes with a hybrid strategy in pediatric heart...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Lin A,Worley S,Brubaker J,Boyle G,Nasman C,Sabella C,Danziger-Isakov LA

更新日期：2012-12-01 00:00:00

abstract：Background:Evaluation for neonatal sepsis routinely includes performing both aerobic and anaerobic blood cultures despite our lack of knowledge of the true incidence of anaerobic bacteremia in this age group and the consequences of not performing these paired cultures. Methods:We performed a retrospective review of al...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Messbarger N,Neemann K

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:P1093 is an ongoing phase I/II multicenter open-label study of dolutegravir plus an optimized background regimen in age-defined pediatric cohorts; here we report the long-term safety and virologic efficacy outcomes for the oldest cohort. METHODS:The study enrolled human immunodeficiency virus type 1 (HIV-1)...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Viani RM,Ruel T,Alvero C,Fenton T,Acosta EP,Hazra R,Townley E,Palumbo P,Buchanan AM,Vavro C,Singh R,Graham B,Anthony P,George K,Wiznia A,P1093 Study Team .

更新日期：2020-04-30 00:00:00

abstract：:Although cryptococcal meningitis is uncommon in children and rare in neonates, it does occur. We highlight circumstances in which the diagnosis should be considered and methods required to confirm the diagnosis in young patients. ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Soni ZJ,Reubenson G,De Maayer T,Coovadia A,Lazarus EM

更新日期：2012-09-01 00:00:00

abstract：:We examined the uptake of rotavirus vaccine and compared trends in acute gastroenteritis (AGE)-associated hospitalizations and outpatient visits among American Indian and Alaska Native (AI/AN) children aged <5 years before and after introduction of the rotavirus vaccine. The rates of AGE-associated hospitalization and...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Grytdal SP,Haberling DL,Kennedy JL,McCollum JT,Parashar UD

更新日期：2018-05-15 00:00:00

abstract：:Across 12 consecutive influenza seasons in Utah, medically-attended visits for laboratory-confirmed influenza infection peaked first among older children (12-18 years). Peak activity in older children preceded that of children 0-4 years by more than 2 days and that of peak activity among adults ≥65 years by more than ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Stockmann C,Pavia AT,Hersh AL,Spigarelli MG,Castle B,Korgenski K,Byington CL,Ampofo K

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Septic arthritis is a serious infection, but the results of blood and joint fluid cultures are often negative in children. We describe here the clinical features and management of culture-negative septic arthritis in children at our hospital and their outcomes. METHODS:We performed a retrospective review of...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Spyridakis E,Gerber JS,Schriver E,Grundmeier RW,Porsch EA,St Geme JW,Downes KJ

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Scrub typhus, caused by Orientia tsutsugamushi, is a major cause of acute febrile illness in children in the rural tropics. METHODS:We recruited 60 febrile pediatric patients with a positive scrub typhus rapid diagnostic test result and 40 healthy controls from Chiang Rai Province in northern Thailand. Diag...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wangrangsimakul T,Greer RC,Chanta C,Nedsuwan S,Blacksell SD,Day NPJ,Paris DH

更新日期：2020-04-30 00:00:00

abstract：:Coronaviruses contribute to the burden of respiratory diseases in children, frequently manifesting in upper respiratory symptoms considered to be part of the "common cold." Recent epidemics of novel coronaviruses recognized in the 21st century have highlighted issues of zoonotic origins of transmissible respiratory vi...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Ogimi C,Kim YJ,Martin ET,Huh HJ,Chiu CH,Englund JA

更新日期：2020-04-30 00:00:00

abstract：:Little information on the efficacy and pharmacokinetics of letermovir among immunocompromised children is currently available. We describe here the use of letermovir in a 2-year-old immunocompromised child with ganciclovir-resistant cytomegalovirus disease who required extracorporeal membrane oxygenation. Detailed inf...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Pérez Marín M,Decosterd LA,Andre P,Buclin T,Mercier T,Murray K,Rizzi M,Meylan P,Jaton-Ogay K,Opota O,Gengler C,Perez MH,Natterer J,Asner SA

更新日期：2020-02-28 00:00:00

abstract：BACKGROUND:Respiratory viruses cause significant morbidity and death in infants; 99% of such deaths occur in resource-limited settings. Risk factors for initial and repeated respiratory viral infections in young infants in resource-limited settings have not been well described. METHODS:From 2011 to 2014, a birth cohor...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Boonyaratanakornkit J,Englund JA,Magaret AS,Bu Y,Tielsch JM,Khatry SK,Katz J,Kuypers J,Shrestha L,LeClerq SC,Steinhoff MC,Chu HY

更新日期：2020-02-28 00:00:00

abstract：BACKGROUND:Our goal was to characterize the epidemiology and clinical significance of congenital Zika virus (ZIKV) exposure by prospectively following a cohort of infants with possible congenital exposure through their first year of life. METHODS:We included infants born in New York City between 2016 and 2017 who had ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Lee EH,Cooper H,Iwamoto M,Lash M,Conners EE,Bloch D,Clark S,Hrusa G,Kubinson H,Paladini M,McGibbon E,Rakeman JL,Fine AD,Limberger RJ,Liu D,Slavinski S,New York City Department of Health and Mental Hygiene Zika Working Gro

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:As antiretroviral therapy (ART) allows the world's 2.3 million human immunodeficiency virus (HIV)-infected children to grow and thrive, these children need to be informed of their HIV status. Neither the prevalence of disclosure to children nor its impact has been evaluated in most resource-limited settings....

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Turissini ML,Nyandiko WM,Ayaya SO,Marete I,Mwangi A,Chemboi V,Warui L,Vreeman RC

更新日期：2013-06-01 00:00:00

abstract：Background:Trichosporonosis is an emerging and often fatal opportunistic fungal infection in immunocompromised patients, particularly those with hematologic malignancy, but data in children are lacking. Methods:We report here 3 cases of invasive infection caused by Trichosporon asahii in pediatric patients with acute ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Foster CE,Edwards MS,Brackett J,Schady DA,Healy CM,Baker CJ

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:Previous studies of cerebrospinal fluid (CSF) shunt infection treatment have been limited in size and unable to compare patient and treatment characteristics by infecting organism. Our objective was to describe variation in patient and treatment characteristics for children with first CSF shunt infection, st...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Simon TD,Kronman MP,Whitlock KB,Browd SR,Holubkov R,Kestle JRW,Kulkarni AV,Langley M,Limbrick DD,Luerssen TG,Oakes J,Riva-Cambrin J,Rozzelle C,Shannon CN,Tamber M,Wellons Iii JC,Whitehead WE,Mayer-Hamblett N,Hydroceph

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:In theory, active surveillance of methicillin-resistant Staphylococcus aureus (MRSA) reduces MRSA spread by identifying all MRSA-colonized patients and placing them under contact precautions. In October 2007, Illinois mandated active MRSA surveillance in all intensive care units, including neonatal intensive...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Lyles RD,Trick WE,Hayden MK,Lolans K,Fogg L,Logan LK,Shulman ST,Weinstein RA,Lin MY,Centers for Disease Control and Prevention, Prevention Epicenters Program.

更新日期：2016-12-01 00:00:00

abstract：:Among 66 antiretroviral-naive children aged <3 years with human immunodeficiency virus (HIV) or coinfected with HIV and tuberculosis and initiating efavirenz-based antiretroviral therapy (ART), non-nucleoside reverse transcriptase inhibitor (NNRTI) resistance was detected before ART in 5 (7.6%). Virologic failure occu...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Higa N,Pelz A,Birch D,Beck IA,Sils T,Samson P,Bwakura-Dangarembizi M,Bolton-Moore C,Capparelli E,Chadwick E,Frenkel LM

更新日期：2020-04-30 00:00:00

abstract：Background:Children undergoing CIC frequently have positive urine culture results and receive many antimicrobial agents. Subsequently, this population is at high risk for infections caused by antimicrobial-resistant bacteria. Resistant pathogens, such as vancomycin-resistant Enterococcus (VRE), carbapenem-resistant Ent...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Forster CS,Courter J,Jackson EC,Mortensen JE,Haslam DB

更新日期：2017-11-24 00:00:00

abstract：Background:Data on long-term toxicity of antiretroviral therapy (ART) in HIV-infected children are sparse. PENPACT-1 was an open-label trial in which HIV-infected children were assigned randomly to receive protease inhibitor (PI)- or nonnucleoside reverse-transcriptase inhibitor (NNRTI)-based ART. Methods:We examined ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Melvin AJ,Warshaw M,Compagnucci A,Saidi Y,Harrison L,Turkova A,Tudor-Williams G,PENPACT-1 (PENTA 9\/PACTG 390\/ANRS 103) Study Team.

更新日期：2017-09-01 00:00:00

abstract：:Children with healthcare-associated Clostridium difficile infection were identified. The incidence increased from 3.2/10,000 patient days in 2007 to 5.2/10,000 patient days in 2011 (p < 0.001). Of 169 isolates, the most common North American Pulsed-Field (NAP) types were NAP4 (n = 43; (25.4%), and NAP1 (n = 25;14.8%) ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Le Saux N,Gravel D,Mulvey M,Moore D,Langley JM,Richardson S,Quach C,Choi KB,Miller M,Katz K,Canadian Nosocomial Infection Surveillance Program.

更新日期：2015-12-01 00:00:00

abstract：:We report here 18 cases of pediatric group A streptococcal toxic shock syndrome, associated clinical findings, and bacterial molecular genetic characteristics discovered through whole-genome sequencing. This comparative whole-genome sequencing revealed unique gene content (speK) and polymorphisms (dpiB) in emm87 group...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Deniskin R,Shah B,Muñoz FM,Flores AR

更新日期：2019-07-01 00:00:00

abstract：:The Advisory Committee on Immunization Practices (ACIP) consists of medical and public health experts who develop recommendations on vaccine use in the United States. The ACIP meets 3 times per year, and members and Centers for Disease Control (CDC) staff present findings and discuss vaccine research, vaccine effectiv...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Schuster JE,O'Leary S,Kimberlin DW

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Endothelial activation may contribute to development of severe disease from Plasmodium falciparum infection, but optimal markers of endothelial activation in severe malaria, the extent of endothelial activation in asymptomatic infection, and the effect of blood group O on endothelial activation have not been...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Park GS,Ireland KF,Opoka RO,John CC

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Invasive mold infections (IMIs) are a leading cause of mortality in immunocompromised children, yet there has never been an international epidemiologic investigation of pediatric IMIs. METHODS:This international, prospective cohort study was performed to characterize the epidemiology, antifungal therapy, an...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wattier RL,Dvorak CC,Hoffman JA,Brozovich AA,Bin-Hussain I,Groll AH,Castagnola E,Knapp KM,Zaoutis TE,Gustafsson B,Sung L,Berman D,Halasa NB,Abzug MJ,Velegraki A,Sharma TS,Fisher BT,Steinbach WJ

更新日期：2015-12-01 00:00:00

abstract：:Recent guidelines recommend empiric vancomycin dosing of 60 mg/kg per day and consideration of higher trough concentrations (15-20 mcg/mL) in children with invasive infections. In this study, we report a retrospective review evaluating the dose/trough relationship and predicted area under the curve in pediatric patien...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Chhim RF,Arnold SR,Lee KR

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Studies describing the activity of imipenem/relebactam against gram-negative bacilli (GNB) isolated from pediatric patients are lacking in the peer-reviewed literature. We address this deficiency by reporting on GNB tested against imipenem/relebactam as part of the Study for Monitoring Antimicrobial Resistan...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Karlowsky JA,Lob SH,Young K,Motyl MR,Sahm DF

更新日期：2020-06-14 00:00:00

abstract：:Pneumonia, most often caused by a respiratory virus, is common in childhood. Mycoplasma pneumoniae also is detected frequently, particularly in older children in the era of pneumococcal conjugate vaccination. Despite recommendations for β-lactam antibiotics, macrolide antibiotics, including erythromycin, clarithromyci...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Blyth CC,Gerber JS

更新日期：2018-02-19 00:00:00

abstract：BACKGROUND:Single-nucleotide polymorphisms (SNPs) in the fucosyltransferase genes FUT2 and FUT3 have been associated with susceptibility to various infectious and inflammatory disorders. FUT variations influence the expression of human histo-blood group antigens (HBGAs) (H-type 1 and Lewis), which are highly expressed ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： King JR,Varadé J,Hammarström L

更新日期：2019-12-27 00:00:00

abstract：BACKGROUND:Data on human immunodeficiency virus (HIV) and hepatitis B virus (HBV) and hepatitis C virus (HCV) coinfection among children in Africa are limited. We evaluated the seroprevalence of both viruses among healthy, HIV-uninfected children and HIV-infected children in the Kilimanjaro region of northern Tanzania....

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Muro FJ,Fiorillo SP,Sakasaka P,Odhiambo C,Reddy EA,Cunningham CK,Buchanan AM

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Shiga toxin (Stx)-producing Escherichia coli (STECs) are the most common cause of acute renal failure in children. The present study evaluated a 10-year STEC polymerase chain reaction screening regimen in children. METHODS:All routine stool culture specimens from patients below 10 years of age (n = 10 342) ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Matussek A,Einemo IM,Jogenfors A,Löfdahl S,Löfgren S

更新日期：2016-06-01 00:00:00