Ledipasvir/Sofosbuvir in Adolescents With Chronic Hepatitis C Genotype 4 With and Without Hematological Disorders: Virological Efficacy and Impact on Liver Stiffness.

abstract：BACKGROUND:The 2017-2018 influenza season was of high severity. Circulating influenza strains change periodically, making it important to determine vaccine effectiveness on an annual basis, especially for susceptible populations. The primary aim of our study was to estimate the effectiveness of the influenza vaccine am...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Powell LN,Bégué RE

更新日期：2020-09-17 00:00:00

abstract：:Perinatal screening for Trypanosoma cruzi in a cohort of 4000 predominantly Hispanic women in southern Texas revealed that Chagas disease occurs with sufficient frequency (0.25%) that targeted perinatal screening should be considered to identify infected mothers and infants at risk for congenital infection. ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Edwards MS,Rench MA,Todd CW,Czaicki N,Steurer FJ,Bern C,Montgomery SP

更新日期：2015-03-01 00:00:00

abstract：Background:Evaluation for neonatal sepsis routinely includes performing both aerobic and anaerobic blood cultures despite our lack of knowledge of the true incidence of anaerobic bacteremia in this age group and the consequences of not performing these paired cultures. Methods:We performed a retrospective review of al...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Messbarger N,Neemann K

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:Studies describing the activity of imipenem/relebactam against gram-negative bacilli (GNB) isolated from pediatric patients are lacking in the peer-reviewed literature. We address this deficiency by reporting on GNB tested against imipenem/relebactam as part of the Study for Monitoring Antimicrobial Resistan...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Karlowsky JA,Lob SH,Young K,Motyl MR,Sahm DF

更新日期：2020-06-14 00:00:00

abstract：Background:Pertussis is an important cause of hospitalization and death in infants too young to be vaccinated (aged <2 months). Limited data on infant pertussis have been reported from Central America. The aim of this study was to characterize acute respiratory illnesses (ARIs) attributable to Bordetella pertussis amon...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Phadke VK,McCracken JP,Kriss JL,Lopez MR,Lindblade KA,Bryan JP,Garcia ME,Funes CE,Omer SB

更新日期：2018-12-03 00:00:00

abstract：BACKGROUND:Despite a high burden of staphylococcal skin disease in children and high incidence of Staphylococcus aureus bacteremia in adult Indigenous populations in northern Australia, there are few studies describing incidence or clinical information of invasive S aureus (ISA) infections in children. METHODS:We cond...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Engelman D,Hofer A,Davis JS,Carapetis JR,Baird RW,Giffard PM,Holt DC,Tong SY

更新日期：2014-12-01 00:00:00

abstract：:Although cryptococcal meningitis is uncommon in children and rare in neonates, it does occur. We highlight circumstances in which the diagnosis should be considered and methods required to confirm the diagnosis in young patients. ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Soni ZJ,Reubenson G,De Maayer T,Coovadia A,Lazarus EM

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The objective was to describe respiratory syncytial virus (RSV) hospitalizations in Alberta, Canada over a 13-year period with an emphasis on the incidence and risk factors for repeat hospitalizations attributable to new RSV infections. METHODS:This was a retrospective database analysis. The Alberta Health ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wong K,Robinson JL,Hawkes MT

更新日期：2020-07-24 00:00:00

abstract：BACKGROUND:This study was designed to determine whether an automated hospital-based influenza vaccination screening program leveraging the electronic medical record (EMR) increases vaccination rates. METHODS:We performed a retrospective cohort study of all children ≥6 months old admitted to medical, surgical, rehabili...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Pollack AH,Kronman MP,Zhou C,Zerr DM

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Cartridge-based nucleic acid amplification test (CB-NAAT) has been recommended for diagnosis of tuberculosis (TB) in children, but its wide use is limited by high cost and the need for well-equipped laboratories. This study was conducted in children with pulmonary TB to compare the diagnostic yield of TB-LAM...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Dayal R,Yadav A,Agarwal D,Kumar M,Kamal R,Singh D,Bhatnagar S

更新日期：2020-03-10 00:00:00

abstract：BACKGROUND:Our goal was to characterize the epidemiology and clinical significance of congenital Zika virus (ZIKV) exposure by prospectively following a cohort of infants with possible congenital exposure through their first year of life. METHODS:We included infants born in New York City between 2016 and 2017 who had ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Lee EH,Cooper H,Iwamoto M,Lash M,Conners EE,Bloch D,Clark S,Hrusa G,Kubinson H,Paladini M,McGibbon E,Rakeman JL,Fine AD,Limberger RJ,Liu D,Slavinski S,New York City Department of Health and Mental Hygiene Zika Working Gro

更新日期：2020-07-13 00:00:00

abstract：Background:Solid organ transplant (SOT) recipients are at risk for invasive fungal disease (IFD). Data on IFD burden in pediatric patients are limited. We aimed to determine the incidence and outcome of IFD in a large cohort of pediatric patients who underwent SOT. Methods:A single-center cohort of pediatric patients ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Saxena S,Gee J,Klieger S,Kajon A,Petersen H,Zaoutis T,Fisher B

更新日期：2018-08-17 00:00:00

abstract：Background:Lower procalcitonin (PCT) concentrations are associated with reduced risk of bacterial community-acquired pneumonia (CAP) in adults, but data in children are limited. Methods:We analyzed serum PCT concentrations from children hospitalized with radiographically confirmed CAP enrolled in the Centers for Disea...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Stockmann C,Ampofo K,Killpack J,Williams DJ,Edwards KM,Grijalva CG,Arnold SR,McCullers JA,Anderson EJ,Wunderink RG,Self WH,Bramley A,Jain S,Pavia AT,Blaschke AJ

更新日期：2018-02-19 00:00:00

abstract：:We determined the rates of community-acquired pneumonia (CAP)-associated hospitalizations and complications in Athens, over a period covering 4 years before and 4 years after the implementation of the 7-valent pneumococcal vaccine (PCV7) in Greece. PCV7 had no impact on pediatric CAP rates, whereas there was an increa...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Lagousi T,Papadatou I,Kopsidas I,Critselis E,Theodoridou M,Spoulou V

更新日期：2015-09-01 00:00:00

abstract：:Children presenting to an emergency department following an animal bite were found to be at risk for infection if they had puncture wounds, crush wounds, or were bitten by a cat. Of the infected wounds that were cultured, methicillin-resistant Staphylococcus aureus was not isolated as a pathogen. ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Ogden RK Jr,Hedican EB,Stach LM,Herigon JC,Jackson MA,Newland JG

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Parechovirus A (PeV-A) is an important cause of sepsis and meningoencephalitis in neonates and young infants. Thus, identifying the source of PeV-A is essential for prevention; however, little is known regarding the spread of PeV-A among family members of PeV-A-infected neonates and young infants. METHODS:I...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Izumita R,Deuchi K,Aizawa Y,Habuka R,Watanabe K,Otsuka T,Saitoh A

更新日期：2019-12-27 00:00:00

abstract：BACKGROUND:Acute gastroenteritis (AGE) in hematopoietic cell transplant (HCT) patients causes significant morbidity and mortality. Data regarding the longitudinal assessment of infectious pathogens during symptomatic AGE and asymptomatic periods, particularly in children, are limited. We investigated the prevalence of ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Schuster JE,Johnston SH,Piya B,Dulek DE,Wikswo ME,McHenry R,Browne H,Gautam R,Bowen MD,Vinjé J,Payne DC,Azimi P,Selvarangan R,Halasa N,Englund JA

更新日期：2020-09-17 00:00:00

abstract：BACKGROUND:In November 2020, the US Food and Drug Administration (FDA) provided Emergency Use Authorizations (EUA) for two novel virus-neutralizing monoclonal antibody therapies, bamlanivimab, and REGN-COV2 (casirivimab plus imdevimab), for the treatment of mild to moderate COVID-19 in adolescents and adults in specifi...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wolf J,Abzug MJ,Wattier RL,Sue PK,Vora SB,Zachariah P,Dulek DE,Waghmare A,Olivero R,Downes KJ,James SH,Pinninti SG,Yarbrough A,Aldrich ML,MacBrayne CE,Soma VL,Grapentine SP,Oliveira CR,Hayes M,Kimberlin DW,Jones S

更新日期：2021-01-03 00:00:00

abstract：BACKGROUND:Single-nucleotide polymorphisms (SNPs) in the fucosyltransferase genes FUT2 and FUT3 have been associated with susceptibility to various infectious and inflammatory disorders. FUT variations influence the expression of human histo-blood group antigens (HBGAs) (H-type 1 and Lewis), which are highly expressed ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： King JR,Varadé J,Hammarström L

更新日期：2019-12-27 00:00:00

abstract：:We examined the uptake of rotavirus vaccine and compared trends in acute gastroenteritis (AGE)-associated hospitalizations and outpatient visits among American Indian and Alaska Native (AI/AN) children aged <5 years before and after introduction of the rotavirus vaccine. The rates of AGE-associated hospitalization and...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Grytdal SP,Haberling DL,Kennedy JL,McCollum JT,Parashar UD

更新日期：2018-05-15 00:00:00

abstract：BACKGROUND:Shiga toxin (Stx)-producing Escherichia coli (STECs) are the most common cause of acute renal failure in children. The present study evaluated a 10-year STEC polymerase chain reaction screening regimen in children. METHODS:All routine stool culture specimens from patients below 10 years of age (n = 10 342) ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Matussek A,Einemo IM,Jogenfors A,Löfdahl S,Löfgren S

更新日期：2016-06-01 00:00:00

abstract：:We conducted a retrospective study to evaluate suboptimal discharge antibiotic prescribing at a children's hospital and found that 27% of the prescriptions were suboptimal. Thirty-three percent of the patients who might have qualified for solid dosage forms received liquid dosages instead. Our findings suggest that op...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Olson J,Thorell EA,Hersh AL

更新日期：2019-12-27 00:00:00

abstract：BACKGROUND:The clinical and economic outcomes associated with pediatric antimicrobial stewardship programs (ASPs) and other supplemental antimicrobial stewardship (AS) interventions have not been well described or reviewed. METHODS:We performed a systematic review using PubMed to identify studies with any of the follo...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Smith MJ,Gerber JS,Hersh AL

更新日期：2015-12-01 00:00:00

abstract：:Achieving rapid and meaningful improvement in healthcare requires the dissemination of quality improvement project results via publication. Doing this well requires detailed descriptions of the complex interventions and of the context in which the improvement took place. This report builds on the first 2 articles in t...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Schondelmeyer AC,Brower LH,Statile AM,White CM,Brady PW

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:Rotavirus is the most common cause of infectious diarrhea in children worldwide. Recent studies have described changes in the burden of all-cause gastroenteritis; however, there are limited data on the clinical and economic impact of rotavirus vaccine on cases of laboratory-confirmed rotavirus disease. METH...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Guerra AH,Stockmann C,Pavia AT,Hersh AL,Thorell EA,Weng HY,Korgenski K,Byington CL,Ampofo K

更新日期：2012-12-01 00:00:00

abstract：Background:Trichosporonosis is an emerging and often fatal opportunistic fungal infection in immunocompromised patients, particularly those with hematologic malignancy, but data in children are lacking. Methods:We report here 3 cases of invasive infection caused by Trichosporon asahii in pediatric patients with acute ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Foster CE,Edwards MS,Brackett J,Schady DA,Healy CM,Baker CJ

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:Scrub typhus, caused by Orientia tsutsugamushi, is a major cause of acute febrile illness in children in the rural tropics. METHODS:We recruited 60 febrile pediatric patients with a positive scrub typhus rapid diagnostic test result and 40 healthy controls from Chiang Rai Province in northern Thailand. Diag...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wangrangsimakul T,Greer RC,Chanta C,Nedsuwan S,Blacksell SD,Day NPJ,Paris DH

更新日期：2020-04-30 00:00:00

abstract：BACKGROUND:Shigella is a leading cause of childhood diarrhea mortality in sub-Saharan Africa. Current World Health Organization guidelines recommend antibiotics for children in non cholera-endemic areas only in the presence of dysentery, a proxy for suspected Shigella infection. METHODS:To assess the sensitivity and s...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Pavlinac PB,Denno DM,John-Stewart GC,Onchiri FM,Naulikha JM,Odundo EA,Hulseberg CE,Singa BO,Manhart LE,Walson JL

更新日期：2016-12-01 00:00:00

abstract：:The reduction in human immunodeficiency virus (HIV) transmission through breastmilk with maternal combination antiretroviral therapy (cART) has led many pregnant women living with HIV and healthcare providers to question exclusive formula feeding in resource-rich settings. Here, we describe cART prophylaxis in 3 breas...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Nashid N,Khan S,Loutfy M,MacGillivray J,Yudin MH,Campbell DM,Barozzino T,Baqi M,Read SE,Bitnun A

更新日期：2020-04-30 00:00:00

abstract：BACKGROUND:In theory, active surveillance of methicillin-resistant Staphylococcus aureus (MRSA) reduces MRSA spread by identifying all MRSA-colonized patients and placing them under contact precautions. In October 2007, Illinois mandated active MRSA surveillance in all intensive care units, including neonatal intensive...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Lyles RD,Trick WE,Hayden MK,Lolans K,Fogg L,Logan LK,Shulman ST,Weinstein RA,Lin MY,Centers for Disease Control and Prevention, Prevention Epicenters Program.

更新日期：2016-12-01 00:00:00