Abstract:
:Biocomposites comprise highly stiff reinforcement elements connected by a compliant matrix material. While the interfacial elastic properties of these biocomposites play a key role in determining the mechanical properties of the entire biocomposite, these properties cannot be measured directly from standard nanomechanical experiments. Developing a method for extracting the interfacial elastic properties in biocomposites is, therefore, a major objective of cutting-edge biomaterials science. Here, using mechanical modeling and Finite-Element simulations, we analyze the interfacial force-depth relationships, stress distribution, and indentation modulus of standard nanoindentation testing in biocomposites, and we establish an analytical framework that connects these results to the elastic properties of the underlying matrix and reinforcement components. The resulting analytical framework is general and holds for a broad range of biocomposites, thus enabling a deeper understanding of the mechanical characteristics of functional interfaces in various biomaterials. Moreover, this framework can be adapted to account for synthetic, microscale, and nanoscale composite materials, and thereby promotes the development of advanced interfacial configurations with specialized mechanical capabilities.
journal_name
J Mech Behav Biomed Materauthors
Shelef Y,Bar-On Bdoi
10.1016/j.jmbbm.2020.104209subject
Has Abstractpub_date
2021-02-01 00:00:00pages
104209eissn
1751-6161issn
1878-0180pii
S1751-6161(20)30751-7journal_volume
114pub_type
杂志文章abstract::An assessment tool to evaluate the degradation of biodegradable materials in a more physiological environment is still needed. Macrophages are critical players in host response, remodeling and degradation. In this study, a cell culture model using monocyte-derived primary macrophages was established to study the degra...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2020.104077
更新日期:2020-12-01 00:00:00
abstract::An optimized thickness of a transplantable auricular silicone scaffold was researched. The original image data were acquired from CT scans, and reverse modeling technology was used to build a digital 3D model of an auricle. The transplant process was simulated in ANSYS Workbench by finite element analysis (FEA), solid...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2015.08.032
更新日期:2016-01-01 00:00:00
abstract::The effect of a dieless drawing process on commercial grade Nickel-Titanium rods, of 5 mm diameter, was investigated by varying the established critical process parameters of temperature, cooling rate, drawing velocity, and heating/cooling velocity. The rods were successfully dieless drawn with a maximum steady state ...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2011.12.013
更新日期:2012-04-01 00:00:00
abstract::Cell seeding of 3D scaffolds is a critical step in tissue engineering since the final tissue properties are related to the initial cell distribution and density within the scaffold unit. Perfusion systems can transport cells to the scaffold however; the fact that cells flow inside the scaffold pores does not guarantee...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2017.08.003
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:To compare the effects of four surface coating methods on resin to zirconia shear bond strength. MATERIAL AND METHODS:Eighty pre-sintered zirconia discs were prepared and randomly divided into five study groups according to the corresponding methods of surface treatments as follows: group C (control group, ...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2013.12.011
更新日期:2014-04-01 00:00:00
abstract::The mechanisms giving rise to vein tortuosity, which is often associated with varicosis, are poorly understood. Recent works suggest that significant biological changes in the wall of varicose veins may precede the mechanical aspects of the disease. To test the hypothesis of tortuosity being a consequence of these cha...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2013.05.006
更新日期:2013-10-01 00:00:00
abstract:STATEMENT OF PROBLEM:The surface hardness and roughness of different glaze materials for denture base acrylic resins have not been well reported. PURPOSE:The purpose of the study was to measure the surfaces hardness, elastic modulus and surface roughness of 5 different light-polymerized glaze materials for poly methyl...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2019.103601
更新日期:2020-03-01 00:00:00
abstract::Clinical meshes used in pelvic organ prolapse (POP) repair are predominantly manufactured from monofilament polypropylene (PP). Complications from the use of these meshes in transvaginal kits, including mesh exposure and pain, have prompted two public health notifications by the FDA. The aim of this study was to compa...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2013.04.002
更新日期:2013-07-01 00:00:00
abstract::This paper presents a constitutive law that predicts the changes in elastic moduli, Poisson's ratio and ultimate tensile strength of bioresorbable polymers due to biodegradation. During biodegradation, long polymer chains are cleaved by hydrolysis reaction. For semi-crystalline polymers, the chain scissions also lead ...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2016.02.026
更新日期:2016-06-01 00:00:00
abstract::Infection incidence for total hip and knee arthroplasty (THA and TKA, respectively) is between 0.2% and 5% and results in approximately 100,000 device failures per year in the United States. Treatment requires prolonged systemic antibiotic therapy with additional surgical revisions. As a prophylactic measure against i...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2018.06.033
更新日期:2018-11-01 00:00:00
abstract::Advances in adhesive technologies have increased indications for the use of inlays. Decrease in the bonded interface integrity due to wear has been cited as the main cause of its failure. However, this process of interface degradation and the influence of inlay material on damage mechanism appear to be poorly understo...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2019.103430
更新日期:2020-01-01 00:00:00
abstract::We report failure analysis of sternal wires in two cases in which a perichronal fixation technique was used to close the sternotomy. Various characteristics of the retrieved wires were compared to those of unused wires of the same grade and same manufacturer and with surgical wire specifications. In both cases, wire f...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2011.02.015
更新日期:2011-10-01 00:00:00
abstract::Oligo(ethylene glycol)-based (OEG) hydrogel samples of varying cross-link densities and degrees of swelling were characterized through dynamic nanoindentation testing. Experiments were performed using a non-standard nanoindentation method, which was validated on a standard polystyrene sample. This method maximizes the...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2015.02.009
更新日期:2015-06-01 00:00:00
abstract::Microinjection is a widely used technique to deliver foreign materials into biological cells. We propose a mathematical model to study the mechanical behavior of a cell in microinjection. Firstly, a cell is modeled by a hyperelastic membrane and interior cytoplasm. Then, based on the fact that the equilibrium configur...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2013.04.017
更新日期:2013-08-01 00:00:00
abstract::Polylactic acid (PLA), one of the most likely green and environmentally friendly materials, is an alternative to petroleum-based plastic. It still remains a challenge to increase the degradation rate and decrease the cost of PLA without compromised mechanical properties. Low cost PLA/wood flour (WF) composite was elab...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2018.08.016
更新日期:2018-12-01 00:00:00
abstract::Observations of the cuticle of the Boston Spiny Lobster using scanning electron microscope (SEM) show that it is a natural biocomposite consisting of chitin fibers and sclerotic-protein matrix with hierarchical and helicoidal structure. The SEM images also indicate that there is a hole-pin joining structure in the cut...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2014.09.001
更新日期:2014-12-01 00:00:00
abstract::Porous scaffolds of Ti-6Al-4V were produced by mixing of this alloy with different amount of magnesium (Mg) powders. The mixtures were compacted in steel die by applying uniaxial pressure of 500 MPa before sintering the compacts in sealed quartz tubes at 900 °C for 2 h. Employing Archimedes׳ principle and Image Tool s...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2015.04.015
更新日期:2015-08-01 00:00:00
abstract::Anterior cruciate ligament (ACL) is a key fibrous connective tissue that maintains the stability of a knee joint and it is the most commonly injured ligament of the knee. A synthetic prosthesis in the form of a braided structure can be an attractive alternative to biological grafts provided that the mechanical propert...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2015.09.018
更新日期:2016-02-01 00:00:00
abstract::Dentin restoration produces weak interfaces because of the effects of bacterial microflora, biofilms, and mechanical, thermal, and shrinkage stresses. This results in secondary caries. Therefore, hydrophobic elastic polyurethane (PU) containing different concentrations of triclosan derivatives was synthesized and appl...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2019.103471
更新日期:2020-02-01 00:00:00
abstract::Considering the interest of the research community in the fatigue behavior of all-ceramic restorations and the time consumed in low-frequency cyclic fatigue tests, this study aimed to investigate the influence of the loading frequency on the zirconia fatigue strength. The biaxial flexural fatigue strength of Y-TZP dis...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2016.01.008
更新日期:2016-08-01 00:00:00
abstract::In an attempt to study the mechanical behavior of bone under indentation, methods of analyses and experimental validations have been developed, with a selected test material. The test material chosen is from an equine cortical bone. Stress-strain relationships are first obtained from conventional mechanical property t...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2014.11.020
更新日期:2015-02-01 00:00:00
abstract::Even though bariatric surgery is one of the most effective treatment option of obesity, post-surgical weight loss is not always ensured, especially in the long term, when many patients experience weight regain. Bariatric procedures are largely based on surgeon's expertise and intra-operative decisions, while an integr...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2020.103883
更新日期:2020-10-01 00:00:00
abstract::The objective was to state zinc contribution in the effectiveness of novel zinc-doped dentin cements to achieve dentin remineralization, throughout a literature or narrative exploratory review. Literature search was conducted using electronic databases, such as PubMed, MEDLINE, DIMDI, Embase, Scopus and Web of Science...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章,评审
doi:10.1016/j.jmbbm.2020.104232
更新日期:2021-02-01 00:00:00
abstract::A limitation in the use of hydrophilic polymers as implantable devices is their inherently poor mechanical strength. Using interpenetrating polymer networks (IPNs) consisting of both hydrophilic and hydrophobic networks is an effective method of strengthening these polymers. In this work, a series of poly(dimethyl sil...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2009.01.002
更新日期:2009-10-01 00:00:00
abstract::Osteoporosis can lead to bone compressive fractures in the lower lumbar vertebrae. In order to assess the recovery of vertebral strength during drug treatment for osteoporosis, it is necessary not only to measure the bone mass but also to perform patient-specific mechanical analyses, since the strength of osteoporotic...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2009.03.001
更新日期:2010-01-01 00:00:00
abstract::It is generally accepted that calcium phosphate (CaP) is one of the most important biomaterials in implant coating applications mainly because of its excellent bioactivity. However, its relatively poor mechanical properties limits its application. This entails that a better understanding of the mechanical properties o...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2010.01.002
更新日期:2010-05-01 00:00:00
abstract::Enamel possesses a complex hierarchical structure, which bestows this tissue with unique mechanical properties. In this study, the mechanical behavior of single enamel rods was investigated under uniaxial compression. Numerical simulations were also performed using micromechanics models for individual enamel rods to i...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2014.10.014
更新日期:2015-02-01 00:00:00
abstract::Fibrin and hyaluronic acid are important components of the provisional wound matrix. Through interactions with fibroblasts, they provide biophysical cues that regulate the viscoelastic properties of the extracellular matrix. To understand the roles of fibrin and hyaluronic acid in a collagenous environment, we used fi...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2018.03.042
更新日期:2018-06-01 00:00:00
abstract::The current study is part of an ongoing research program to develop an advanced new carbon fiber/flax/epoxy (CF/flax/epoxy) hybrid composite with a “sandwich structure” as a substitute for metallic materials for orthopedic long bone fracture plate applications. The purpose of this study was to assess the fatigue prope...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:
更新日期:2014-07-01 00:00:00
abstract::Haversian remodeling is known to result in improved resistance to compressive fracture in healthy cortical bone. Here, we examine the individual roles of the mean porosity, structure of the network of pores and remodeled bone matrix properties in the fracture behavior of Haversian bone. The detailed structure of poros...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2018.04.013
更新日期:2018-07-01 00:00:00