Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs.

abstract：:We present a test-retest dataset for evaluation of long-term reliability of measures from structural and resting-state functional magnetic resonance imaging (sMRI and rfMRI) scans. The repeated scan dataset was collected from 61 healthy adults in two sessions using highly similar imaging parameters at an interval of 1...

journal_title：Scientific data

authors： Huang L,Huang T,Zhen Z,Liu J

更新日期：2016-03-15 00:00:00

abstract：:The human HCC1806 cell line is frequently used as a preclinical model for triple negative breast cancer (TNBC). Given that dysregulated epigenetic mechanisms are involved in cancer pathogenesis, emerging therapeutic strategies target chromatin regulators, such as histone deacetylases. A comprehensive understanding of ...

journal_title：Scientific data

authors： Perreault AA,Sprunger DM,Venters BJ

更新日期：2019-03-05 00:00:00

abstract：:Between the 2011 and 2016 national censuses, the Australian Bureau of Statistics changed its anonymity policy compliance system for the distribution of census data. The new method has resulted in dramatic inconsistencies when comparing low-resolution data to aggregated high-resolution data. Hence, aggregated totals do...

journal_title：Scientific data

authors： Fair KM,Zachreson C,Prokopenko M

更新日期：2019-08-16 00:00:00

abstract：:Rett syndrome is an X-linked neurodevelopmental disorder caused by mutation in the methyl-CpG-binding protein 2 gene (MECP2) in the majority of cases. We describe an RNA sequencing dataset of postmortem brain tissue samples from four females clinically diagnosed with Rett syndrome and four age-matched female donors. T...

journal_title：Scientific data

authors： Aldinger KA,Timms AE,MacDonald JW,McNamara HK,Herstein JS,Bammler TK,Evgrafov OV,Knowles JA,Levitt P

更新日期：2020-06-19 00:00:00

abstract：:Lysosomes are the main degradative organelles of cells and involved in a variety of processes including the recycling of macromolecules, storage of compounds, and metabolic signaling. Despite an increasing interest in the proteomic analysis of lysosomes, no systematic study of sample preparation protocols for lysosome...

journal_title：Scientific data

authors： Ponnaiyan S,Akter F,Singh J,Winter D

更新日期：2020-02-26 00:00:00

abstract：:In the last few decades, data-driven methods have come to dominate many fields of scientific inquiry. Open data and open-source software have enabled the rapid implementation of novel methods to manage and analyze the growing flood of data. However, it has become apparent that many scientific fields exhibit distressin...

journal_title：Scientific data

authors： Pasquier T,Lau MK,Trisovic A,Boose ER,Couturier B,Crosas M,Ellison AM,Gibson V,Jones CR,Seltzer M

更新日期：2017-09-05 00:00:00

abstract：:Both poly(A) enrichment and ribosomal RNA depletion are commonly used for RNA sequencing. Either has its advantages and disadvantages that may lead to biases in the downstream analyses. To better access these effects, we carried out both ribosomal RNA-depleted and poly(A)-selected RNA-seq for CD4+ T naive cells isolat...

journal_title：Scientific data

authors： Chen L,Yang R,Kwan T,Tang C,Watt S,Zhang Y,Bourque G,Ge B,Downes K,Frontini M,Ouwehand WH,Lin JW,Soranzo N,Pastinen T,Chen L

更新日期：2020-11-09 00:00:00

abstract：:Functional trait databases are emerging as crucial tools for a wide range of ecological studies across the world. Here, we provide a database of functional traits for vascular plant species of the Mediterranean Basin. The database includes 25,764 individual records of 44 traits from 2,457 plant taxa distributed in 119...

journal_title：Scientific data

authors： Tavşanoğlu Ç,Pausas JG

更新日期：2018-07-10 00:00:00

abstract：:Olympia oysters are found along the west coast of North America and as the only native oyster species in the region, receive considerable attention with regard to restoration and conservation. Knowledge of genetic structure of this species is essential for resource managers. Here we provide genetic data for three dist...

journal_title：Scientific data

authors： White SJ,Vadopalas B,Silliman K,Roberts SB

更新日期：2017-09-12 00:00:00

abstract：:Many animal phyla have no representatives within the catalog of whole metazoan genome sequences. This dataset fills in one gap in the genome knowledge of animal phyla with a draft genome of Bugula neritina (phylum Bryozoa). Interest in this species spans ecology and biomedical sciences because B. neritina is the natur...

journal_title：Scientific data

authors： Rayko M,Komissarov A,Kwan JC,Lim-Fong G,Rhodes AC,Kliver S,Kuchur P,O'Brien SJ,Lopez JV

更新日期：2020-10-20 00:00:00

abstract：:In Eco-Metabolomics interactions are studied of non-model organisms in their natural environment and relations are made between biochemistry and ecological function. Current challenges when processing such metabolomics data involve complex experiment designs which are often carried out in large field campaigns involvi...

journal_title：Scientific data

authors： Peters K,Gorzolka K,Bruelheide H,Neumann S

更新日期：2018-08-28 00:00:00

abstract：:Transparent evaluations of FAIRness are increasingly required by a wide range of stakeholders, from scientists to publishers, funding agencies and policy makers. We propose a scalable, automatable framework to evaluate digital resources that encompasses measurable indicators, open source tools, and participation guide...

journal_title：Scientific data

authors： Wilkinson MD,Dumontier M,Sansone SA,Bonino da Silva Santos LO,Prieto M,Batista D,McQuilton P,Kuhn T,Rocca-Serra P,Crosas M,Schultes E

更新日期：2019-09-20 00:00:00

abstract：:This article presents data derived from a 36 year-long uninterrupted observational study of amphibian populations living in the city and vicinity of Yekaterinburg, Russia. This area is inhabited by six amphibian species. Based on a degree of anthropogenic transformation, the urban territory is divided into five highly...

journal_title：Scientific data

authors： Vershinin VL,Vershinina SD,Berzin DL,Zmeeva DV,Kinev AV

更新日期：2015-05-12 00:00:00

abstract：:Gene expression is a biological process regulated at different molecular levels, including chromatin accessibility, transcription, and RNA maturation and transport. In addition, these regulatory mechanisms have strong links with cellular metabolism. Here we present a multi-omics dataset that captures different aspects...

journal_title：Scientific data

authors： Nuño-Cabanes C,Ugidos M,Tarazona S,Martín-Expósito M,Ferrer A,Rodríguez-Navarro S,Conesa A

更新日期：2020-02-27 00:00:00

abstract：:Serial electron microscopy techniques have proven to be a powerful tool in biology. Unfortunately, the data sets they generate lack robust and accurate automated segmentation algorithms. In this data descriptor publication, we introduce a serial focused ion beam scanning electron microscopy (FIB-SEM) dataset consistin...

journal_title：Scientific data

authors： Ivanchenko MV,Cicconet M,Jandal HA,Wu X,Corey DP,Indzhykulian AA

更新日期：2020-06-17 00:00:00

abstract：:Metastatic colorectal cancer is a leading cause of cancer death. However, current therapy options are limited to chemotherapy, with the addition of anti-EGFR antibodies for patients with RAS wild-type tumours. Novel drug targets, or drug combinations that induce a synergistic response, would be of great benefit to pat...

journal_title：Scientific data

authors： Williams SP,Barthorpe AS,Lightfoot H,Garnett MJ,McDermott U

更新日期：2017-10-03 00:00:00

abstract：:Gene-gene (GXG) and gene-environment (GXE) interactions play important roles in pharmacogenetics study. Simultaneously incorporating multiple single nucleotide polymorphisms (SNPs) and clinical factors is needed to explore the association of their interactions with drug response and toxicity phenotypes. We genotyped 5...

journal_title：Scientific data

authors： Wang LY,Cui JJ,Liu JY,Guo AX,Zhao ZY,Liu YZ,Wu JC,Li M,Hu CP,Gao Y,Zhou HH,Yin JY

更新日期：2018-12-11 00:00:00

abstract：:Long-term exposure to air pollution is considered a major public health concern and has been related to overall mortality and various diseases such as respiratory and cardiovascular disease. Due to the spatial variability of air pollution concentrations, assessment of individual exposure to air pollution requires spat...

journal_title：Scientific data

authors： Schmitz O,Beelen R,Strak M,Hoek G,Soenario I,Brunekreef B,Vaartjes I,Dijst MJ,Grobbee DE,Karssenberg D

更新日期：2019-03-12 00:00:00

abstract：:In response to the COVID-19 pandemic, governments have implemented a wide range of non-pharmaceutical interventions (NPIs). Monitoring and documenting government strategies during the COVID-19 crisis is crucial to understand the progression of the epidemic. Following a content analysis strategy of existing public info...

journal_title：Scientific data

authors： Desvars-Larrive A,Dervic E,Haug N,Niederkrotenthaler T,Chen J,Di Natale A,Lasser J,Gliga DS,Roux A,Sorger J,Chakraborty A,Ten A,Dervic A,Pacheco A,Jurczak A,Cserjan D,Lederhilger D,Bulska D,Berishaj D,Tames EF,Álv

更新日期：2020-08-27 00:00:00

abstract：:Polyadenylation plays an important role in gene regulation, thus affecting a wide variety of biological processes. In the rice blast fungus Magnaporthe oryzae the cleavage factor I protein Rpb35 is required for pre-mRNA polyadenylation and fungal virulence. Here we present the bioinformatic approach and output data re...

journal_title：Scientific data

authors： Marconi M,Sesma A,Rodríguez-Romero JL,González MLR,Wilkinson MD

更新日期：2018-11-27 00:00:00

abstract：:In angiogenesis with concurrent inflammation, many pathways are activated, some linked to VEGF and others largely VEGF-independent. Pathways involving inflammatory mediators, chemokines, and micro-RNAs may play important roles in maintaining a pro-angiogenic environment or mediating angiogenic regression. Here, we des...

journal_title：Scientific data

authors： Mukwaya A,Lindvall JM,Xeroudaki M,Peebo B,Ali Z,Lennikov A,Jensen LD,Lagali N

更新日期：2016-11-22 00:00:00

abstract：:Long-term datasets of number and size of lakes over the Tibetan Plateau (TP) are among the most critical components for better understanding the interactions among the cryosphere, hydrosphere, and atmosphere at regional and global scales. Due to the harsh environment and the scarcity of data over the TP, data accumula...

journal_title：Scientific data

authors： Wan W,Long D,Hong Y,Ma Y,Yuan Y,Xiao P,Duan H,Han Z,Gu X

更新日期：2016-06-21 00:00:00

abstract：:Larval fishes are a useful metric of marine ecosystem state and change, as well as species-specific patterns in phenology. The high level of taxonomic expertise required to identify larval fishes to species level, and the considerable effort required to collect samples, make these data very valuable. Here we collate 3...

journal_title：Scientific data

authors： Smith JA,Miskiewicz AG,Beckley LE,Everett JD,Garcia V,Gray CA,Holliday D,Jordan AR,Keane J,Lara-Lopez A,Leis JM,Matis PA,Muhling BA,Neira FJ,Richardson AJ,Smith KA,Swadling KM,Syahailatua A,Taylor MD,van Ruth PD,W

更新日期：2018-10-16 00:00:00

abstract：:Eicosanoids comprise a class of bioactive lipids derived from a unique group of essential fatty acids that mediate a variety of important physiological functions. Owing to the structural diversity of these lipids, their analysis in biological samples is often a major challenge. Advancements in mass spectrometric have ...

journal_title：Scientific data

authors： Sorgi CA,Peti APF,Petta T,Meirelles AFG,Fontanari C,Moraes LAB,Faccioli LH

更新日期：2018-08-21 00:00:00

abstract：:The use of hydrogen (H2) as a substitute for fossil fuel, which accounts for the majority of the world's energy, is environmentally the most benign option for the reduction of CO2 emissions. This will require gigawatt-scale storage systems and as such, H2 storage in porous rocks in the subsurface will be required. Acc...

journal_title：Scientific data

authors： Hassanpouryouzband A,Joonaki E,Edlmann K,Heinemann N,Yang J

更新日期：2020-07-09 00:00:00

abstract：:Direct-infusion mass spectrometry (DIMS) metabolomics is an important approach for characterising molecular responses of organisms to disease, drugs and the environment. Increasingly large-scale metabolomics studies are being conducted, necessitating improvements in both bioanalytical and computational workflows to ma...

journal_title：Scientific data

authors： Kirwan JA,Weber RJ,Broadhurst DI,Viant MR

更新日期：2014-06-10 00:00:00

abstract：:Trait-based approaches advance ecological and evolutionary research because traits provide a strong link to an organism's function and fitness. Trait-based research might lead to a deeper understanding of the functions of, and services provided by, ecosystems, thereby improving management, which is vital in the curren...

journal_title：Scientific data

authors： Madin JS,Anderson KD,Andreasen MH,Bridge TC,Cairns SD,Connolly SR,Darling ES,Diaz M,Falster DS,Franklin EC,Gates RD,Harmer A,Hoogenboom MO,Huang D,Keith SA,Kosnik MA,Kuo CY,Lough JM,Lovelock CE,Luiz O,Martinelli J

更新日期：2016-03-29 00:00:00

abstract：:Outlier analyses are central to scientific data assessments. Conventional outlier identification methods do not work effectively for Protein Data Bank (PDB) data, which are characterized by heavy skewness and the presence of bounds and/or long tails. We have developed a data-driven nonparametric method to identify out...

journal_title：Scientific data

authors： Shao C,Liu Z,Yang H,Wang S,Burley SK

更新日期：2018-12-11 00:00:00

abstract：:Ticks carry pathogens that can cause disease in both animals and humans, and there is a need to monitor the distribution and abundance of ticks and the pathogens they carry to pinpoint potential high risk areas for tick-borne disease transmission. In a joint Scandinavian study, we measured Ixodes ricinus instar abunda...

journal_title：Scientific data

authors： Kjær LJ,Klitgaard K,Soleng A,Edgar KS,Lindstedt HEH,Paulsen KM,Andreassen ÅK,Korslund L,Kjelland V,Slettan A,Stuen S,Kjellander P,Christensson M,Teräväinen M,Baum A,Jensen LM,Bødker R

更新日期：2020-07-16 00:00:00

abstract：:We performed whole-genome sequencing for eight inbred rat strains commonly used in genetic mapping studies. They are the founders of the NIH heterogeneous stock (HS) outbred colony. We provide their sequences and variant calls to the rat genomics community. When analyzing the variant calls we identified regions with u...

journal_title：Scientific data

authors： Ramdas S,Ozel AB,Treutelaar MK,Holl K,Mandel M,Woods LCS,Li JZ

更新日期：2019-04-23 00:00:00