Gene-gene and gene-environment interaction data for platinum-based chemotherapy in non-small cell lung cancer.

abstract：:Neural microarchitecture is heterogeneous, varying both across and within brain regions. The consistent identification of regions of interest is one of the most critical aspects in examining neurocircuitry, as these structures serve as the vital landmarks with which to map brain pathways. Access to continuous, three-d...

journal_title：Scientific data

authors： Prasad JA,Balwani AH,Johnson EC,Miano JD,Sampathkumar V,De Andrade V,Fezzaa K,Du M,Vescovi R,Jacobsen C,Kording KP,Gürsoy D,Gray Roncal W,Kasthuri N,Dyer EL

更新日期：2020-10-20 00:00:00

abstract：:Advances in high-throughput sequencing are reshaping how we perceive microbial communities inhabiting the human body, with implications for therapeutic interventions. Several large-scale datasets derived from hundreds of human microbiome samples sourced from multiple studies are now publicly available. However, idiosy...

journal_title：Scientific data

authors： Hahn AS,Altman T,Konwar KM,Hanson NW,Kim D,Relman DA,Dill DL,Hallam SJ

更新日期：2017-04-11 00:00:00

abstract：:Populations in resource dependent economies gain well-being from the natural environment, in highly spatially and temporally variable patterns. To collect information on this, we designed and implemented a 1586-household quantitative survey in the southwest coastal zone of Bangladesh. Data were collected on material, ...

journal_title：Scientific data

authors： Adams H,Adger WN,Ahmad S,Ahmed A,Begum D,Lázár AN,Matthews Z,Rahman MM,Streatfield PK

更新日期：2016-11-08 00:00:00

abstract：:We performed whole-genome sequencing for eight inbred rat strains commonly used in genetic mapping studies. They are the founders of the NIH heterogeneous stock (HS) outbred colony. We provide their sequences and variant calls to the rat genomics community. When analyzing the variant calls we identified regions with u...

journal_title：Scientific data

authors： Ramdas S,Ozel AB,Treutelaar MK,Holl K,Mandel M,Woods LCS,Li JZ

更新日期：2019-04-23 00:00:00

abstract：:Human adenoviruses (HAdVs) are fatal to immuno-suppressed individuals, but no effective anti-HAdV therapy is available. Here, we present a novel image-based high-throughput screening (HTS) platform, which scores the full viral replication cycle from virus entry to dissemination of progeny and second-round infections. ...

journal_title：Scientific data

authors： Georgi F,Kuttler F,Murer L,Andriasyan V,Witte R,Yakimovich A,Turcatti G,Greber UF

更新日期：2020-08-12 00:00:00

abstract：:The COVID-19 pandemic has ignited interest in age-specific manifestations of infection but surprisingly little is known about relative severity of infectious disease between the extremes of age. In a systematic analysis we identified 142 datasets with information on severity of disease by age for 32 different infectio...

journal_title：Scientific data

authors： Glynn JR,Moss PAH

更新日期：2020-10-15 00:00:00

abstract：:Lysosomes are the main degradative organelles of cells and involved in a variety of processes including the recycling of macromolecules, storage of compounds, and metabolic signaling. Despite an increasing interest in the proteomic analysis of lysosomes, no systematic study of sample preparation protocols for lysosome...

journal_title：Scientific data

authors： Ponnaiyan S,Akter F,Singh J,Winter D

更新日期：2020-02-26 00:00:00

abstract：:In the last few decades, data-driven methods have come to dominate many fields of scientific inquiry. Open data and open-source software have enabled the rapid implementation of novel methods to manage and analyze the growing flood of data. However, it has become apparent that many scientific fields exhibit distressin...

journal_title：Scientific data

authors： Pasquier T,Lau MK,Trisovic A,Boose ER,Couturier B,Crosas M,Ellison AM,Gibson V,Jones CR,Seltzer M

更新日期：2017-09-05 00:00:00

abstract：:While tick-borne zoonoses, such as Lyme disease and tick-borne encephalitis, present an increasing global concern, knowledge of their vectors' distribution remains limited, especially for China. In this paper, we present the first comprehensive dataset of known tick species and their distributions in China, derived fr...

journal_title：Scientific data

authors： Zhang G,Zheng D,Tian Y,Li S

更新日期：2019-07-01 00:00:00

abstract：:We present The Odonate Phenotypic Database (OPD): an online data resource of dragonfly and damselfly phenotypes (Insecta: Odonata). Odonata is a relatively small insect order that currently consists of about 6400 species belonging to 32 families. The database consists of multiple morphological, life-history and behavi...

journal_title：Scientific data

authors： Waller JT,Willink B,Tschol M,Svensson EI

更新日期：2019-12-12 00:00:00

abstract：:This corrects the article DOI: 10.1038/sdata.2017.139. ...

journal_title：Scientific data

authors： Williams SP,Barthorpe AS,Lightfoot H,Garnett MJ,McDermott U

更新日期：2018-10-09 00:00:00

abstract：:Plants use surface receptors to perceive information about many aspects of their local environment. These receptors physically interact to form both steady state and signalling competent complexes. The signalling events downstream of receptor activation impact both plant developmental and immune responses. Here, we pr...

journal_title：Scientific data

authors： Mott GA,Smakowska-Luzan E,Pasha A,Parys K,Howton TC,Neuhold J,Lehner A,Grünwald K,Stolt-Bergner P,Provart NJ,Mukhtar MS,Desveaux D,Guttman DS,Belkhadir Y

更新日期：2019-02-26 00:00:00

abstract：:Human motion capture is commonly used in various fields, including sport, to analyze, understand, and synthesize kinematic and kinetic data. Specialized computer vision and marker-based optical motion capture techniques constitute the gold-standard for accurate and robust human motion capture. The dataset presented co...

journal_title：Scientific data

authors： Szczęsna A,Błaszczyszyn M,Pawlyta M

更新日期：2021-01-18 00:00:00

abstract：:Induced pluripotent stem cells (iPSCs) and human embryonic stem cells (hESCs) differentiated into hepatocyte-like cells (HLCs) provide a defined and renewable source of cells for drug screening, toxicology and regenerative medicine. We previously reprogrammed human fetal foreskin fibroblast cells (HFF1) into iPSCs emp...

journal_title：Scientific data

authors： Wruck W,Adjaye J

更新日期：2018-03-13 00:00:00

abstract：:Eicosanoids comprise a class of bioactive lipids derived from a unique group of essential fatty acids that mediate a variety of important physiological functions. Owing to the structural diversity of these lipids, their analysis in biological samples is often a major challenge. Advancements in mass spectrometric have ...

journal_title：Scientific data

authors： Sorgi CA,Peti APF,Petta T,Meirelles AFG,Fontanari C,Moraes LAB,Faccioli LH

更新日期：2018-08-21 00:00:00

abstract：:The behaviors of building occupants have continued to perplex scholars for years in our attempts to develop models for energy efficient housing. Building simulations, project delivery approaches, policies, and more have fell short of their optimistic goals due to the complexity of human behavior. As a part of a multip...

journal_title：Scientific data

authors： Paige F,Agee P,Jazizadeh F

更新日期：2019-11-26 00:00:00

abstract：:We have developed a new coastal database for the Mediterranean basin that is intended for coastal impact and adaptation assessment to sea-level rise and associated hazards on a regional scale. The data structure of the database relies on a linear representation of the coast with associated spatial assessment units. Us...

journal_title：Scientific data

authors： Wolff C,Vafeidis AT,Muis S,Lincke D,Satta A,Lionello P,Jimenez JA,Conte D,Hinkel J

更新日期：2018-03-27 00:00:00

abstract：:Although a key driver of Earth's climate system, global land-atmosphere energy fluxes are poorly constrained. Here we use machine learning to merge energy flux measurements from FLUXNET eddy covariance towers with remote sensing and meteorological data to estimate global gridded net radiation, latent and sensible heat...

journal_title：Scientific data

authors： Jung M,Koirala S,Weber U,Ichii K,Gans F,Camps-Valls G,Papale D,Schwalm C,Tramontana G,Reichstein M

更新日期：2019-05-27 00:00:00

abstract：:The Tropical Rainfall Measuring Mission (TRMM) Multisatellite Precipitation Analysis (TMPA) product provided over 17 years of gridded precipitation datasets. However, the accuracy and spatial resolution of TMPA limits the applicability in hydrometeorological applications. We present a dataset that enhances the accurac...

journal_title：Scientific data

authors： Hashemi H,Fayne J,Lakshmi V,Huffman GJ

更新日期：2020-03-03 00:00:00

abstract：:The big-headed turtle, Platysternon megacephalum, as the sole member of the monotypic family Platysternidae, has a number of distinct characteristics including an extra-large head, long tail, flat carapace, and a preference for low water temperature environments. We performed whole genome sequencing, assembly, and gen...

journal_title：Scientific data

authors： Cao D,Wang M,Ge Y,Gong S

更新日期：2019-05-16 00:00:00

abstract：:The Serengeti ecosystem spans an extensive network of protected areas in Tanzania, eastern Africa, and a UNESCO Wold Heritage Site. It is home to some of the largest animal migrations on the planet. Here, we describe a dataset consisting of the sample counts of three age classes (infant, juvenile and adult) of 13 ungu...

journal_title：Scientific data

authors： Rogy P,Sinclair ARE

更新日期：2020-10-21 00:00:00

abstract：:Structural studies of challenging targets such as G protein-coupled receptors (GPCRs) have accelerated during the last several years due to the development of new approaches, including small-wedge and serial crystallography. Here, we describe the deposition of seven datasets consisting of X-ray diffraction images acqu...

journal_title：Scientific data

authors： Marin E,Luginina A,Gusach A,Kovalev K,Bukhdruker S,Khorn P,Polovinkin V,Lyapina E,Rogachev A,Gordeliy V,Mishin A,Cherezov V,Borshchevskiy V

更新日期：2020-11-12 00:00:00

abstract：:The human HCC1806 cell line is frequently used as a preclinical model for triple negative breast cancer (TNBC). Given that dysregulated epigenetic mechanisms are involved in cancer pathogenesis, emerging therapeutic strategies target chromatin regulators, such as histone deacetylases. A comprehensive understanding of ...

journal_title：Scientific data

authors： Perreault AA,Sprunger DM,Venters BJ

更新日期：2019-03-05 00:00:00

abstract：:Mesenchymal stem/stromal cells (MSCs) were identified in most tissues of an adult organism. MSCs mediate physiological renewal, as well as regulation of tissue homeostasis, reparation and regeneration. Functions of MSCs are regulated by endocrine and neuronal signals, and noradrenaline is one of the most important MSC...

journal_title：Scientific data

authors： Tyurin-Kuzmin PA,Dyikanov DT,Fadeeva JI,Sysoeva VY,Kalinina NI

更新日期：2018-10-02 00:00:00

abstract：:The use of DNA metabarcoding to characterise the biodiversity of environmental and community samples has exploded in recent years. However, taxonomic inferences from these studies are contingent on the quality and completeness of the sequence reference database used to characterise sample species-composition. In respo...

journal_title：Scientific data

authors： Arranz V,Pearman WS,Aguirre JD,Liggins L

更新日期：2020-07-03 00:00:00

abstract：:Size-resolved aerosol samples were collected in Metro Manila between July 2018 and October 2019. Two Micro-Orifice Uniform Deposit Impactors (MOUDI) were deployed at Manila Observatory in Quezon City, Metro Manila with samples collected on a weekly basis for water-soluble speciation and mass quantification. Additional...

journal_title：Scientific data

authors： Stahl C,Cruz MT,Bañaga PA,Betito G,Braun RA,Aghdam MA,Cambaliza MO,Lorenzo GR,MacDonald AB,Pabroa PC,Yee JR,Simpas JB,Sorooshian A

更新日期：2020-04-29 00:00:00

abstract：:This paper presents a dataset obtained from fifty four laboratory experiments of the breaching of fluvial dikes due to flow overtopping. Data were collected on two complementary experimental setups, each consisting of a main channel representing the river, an erodible lateral dike and a floodplain. The dataset covers ...

journal_title：Scientific data

authors： Rifai I,El Kadi Abderrezzak K,Erpicum S,Archambeau P,Violeau D,Pirotton M,Dewals B

更新日期：2019-05-13 00:00:00

abstract：:One important use of genome-wide transcriptional profiles is to identify relationships between transcription levels and patient outcomes. These translational insights can guide the development of biomarkers for clinical application. Data from thousands of translational-biomarker studies have been deposited in public r...

journal_title：Scientific data

authors： Golightly NP,Bell A,Bischoff AI,Hollingsworth PD,Piccolo SR

更新日期：2018-04-17 00:00:00

abstract：:Confident identification of unknown chemicals in high resolution mass spectrometry (HRMS) screening studies requires cohesive workflows and complementary data, tools, and software. Chemistry databases, screening libraries, and chemical metadata have become fixtures in identification workflows. To increase confidence i...

journal_title：Scientific data

authors： McEachran AD,Balabin I,Cathey T,Transue TR,Al-Ghoul H,Grulke C,Sobus JR,Williams AJ

更新日期：2019-08-02 00:00:00

abstract：:Climate change has already influenced lake temperatures globally, but understanding future change is challenging. The response of lakes to changing climate drivers is complex due to the nature of lake-atmosphere coupling, ice cover, and stratification. To better understand the diversity of lake responses to climate ch...

journal_title：Scientific data

authors： Winslow LA,Hansen GJA,Read JS,Notaro M

更新日期：2017-04-25 00:00:00