Abstract:
:In this paper, a method for apnea bradycardia detection in preterm infants is presented based on coupled hidden semi Markov model (CHSMM). CHSMM is a generalization of hidden Markov models (HMM) used for modeling mutual interactions among different observations of a stochastic process through using finite number of hidden states with corresponding resting time. We introduce a new set of equations for CHSMM to be integrated in a detection algorithm. The detection algorithm was evaluated on a simulated data to detect a specific dynamic and on a clinical dataset of electrocardiogram signals collected from preterm infants for early detection of apnea bradycardia episodes. For simulated data, the proposed algorithm was able to detect the desired dynamic with sensitivity of 96.67% and specificity of 98.98%. Furthermore, the method detected the apnea bradycardia episodes with 94.87% sensitivity and 96.52% specificity with mean time delay of 0.73 s. The results show that the algorithm based on CHSMM is a robust tool for monitoring of preterm infants in detecting apnea bradycardia episodes. Graphical Abstract Apnea Bradycardia detection using Coupled hidden semi Markov Model from electrocardiography. In this model, a sequence of hidden states is assigned to each observation based on the effects of previous states of all observations.
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Montazeri Ghahjaverestan N,Shamsollahi MB,Ge D,Beuchée A,Hernández AIdoi
10.1007/s11517-020-02277-8subject
Has Abstractpub_date
2021-01-01 00:00:00pages
1-11issue
1eissn
0140-0118issn
1741-0444pii
10.1007/s11517-020-02277-8journal_volume
59pub_type
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