当前位置： SCI文献检索 > MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING期刊下所有文献 > Theoretical study of the effect of local flow disturbances on the concentration of low-density lipoproteins at the luminal surface of end-to-end anastomosed vessels.

Theoretical study of the effect of local flow disturbances on the concentration of low-density lipoproteins at the luminal surface of end-to-end anastomosed vessels.

Abstract：

:To elucidate the mechanisms of localisation of intimal hyperplasia in anastomosed arteries, the effects of flow disturbances on the transport of low-density lipoproteins (LDLs) from the flowing blood to the wall of end-to-end anastomosed arteries, with and without a moderate stenosis, were studied theoretically by means of a computer simulation under the condition of steady flow. In an artery with moderate stenosis at the anastomotic junction and intimal thickening distal to it, we found that, owing to the water-permeable nature of the arterial wall, the surface concentration of LDL was elevated up to 20% higher than that of the bulk flow distal to the stenosis, where a recirculation zone was formed and wall shear stresses were low. In contrast to this, no significant elevation of surface concentration of LDLs occurred in another anastomosed vessel in which no stenosis was formed and no intimal thickening was observed. These results suggest that flow-dependent concentration polarisation of LDLs plays a causative role in the localisation of anastomotic intimal hyperplasia in the human arterial system by locally elevating the surface concentration of LDLs, thus augmenting their uptake by endothelial cells.

journal_name

Med Biol Eng Comput

journal_title

Medical & biological engineering & computing

authors

Wada S,Koujiya M,Karino T

doi

10.1007/BF02345458

keywords:

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

576-87

issue

5

eissn

0140-0118

issn

1741-0444

journal_volume

40

pub_type

杂志文章

相关文献

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING文献大全
  • Influence of ionic shifts during dialysis on volume estimations with multifrequency impedance analysis.

    abstract：:During dialysis the ion concentrations in many body fluids change significantly. The influence of these changes on the accuracy of volume measurements with bioimpedance spectroscopy is investigated by the following procedure: Plasma ion concentrations and impedance spectra (5-500 kHz) are measured during six standard ...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02534137

    authors： Scharfetter H,Wirnsberger GH,Holzer H,Hutten H

    更新日期：1997-03-01 00:00:00

  • Reliability of the mechanomyogram detected with an accelerometer during voluntary contractions.

    abstract：:The accelerometer is used for mechanomyogram (MMG) recordings of muscle contractions. Although the mechanical characteristics of other MMG transducers have been determined with reference to the accelerometer, mechanical aspects of the accelerometer itself, including the weight of the transducer, have not been verified...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02344888

    authors： Watakabe M,Mita K,Akataki K,Ito K

    更新日期：2003-03-01 00:00:00

  • Fluid flow and particle transport in mechanically ventilated airways. Part II: particle transport.

    abstract：:The flow mechanisms that play a role on aerosol deposition were identified and presented in a companion paper (Timothy et al. in Med Biol Eng Comput. doi: 10.1007/s11517-015-1407-3 , 2015). In the current paper, the effects of invasive conventional mechanical ventilation waveforms and endotracheal tube (ETT) on the ae...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-015-1408-2

    authors： Alzahrany M,Van Rhein T,Banerjee A,Salzman G

    更新日期：2016-07-01 00:00:00

  • Multiscale entropy-based approach to automated surface EMG classification of neuromuscular disorders.

    abstract：:We introduce a novel method for an automatic classification of subjects to those with or without neuromuscular disorders. This method is based on multiscale entropy of recorded surface electromyograms (sEMGs) and support vector classification. The method was evaluated on a single-channel experimental sEMGs recorded fr...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-010-0629-7

    authors： Istenic R,Kaplanis PA,Pattichis CS,Zazula D

    更新日期：2010-08-01 00:00:00

  • Biphasic model of the trabecular meshwork in the eye.

    abstract：:A biphasic continuum model for the flow of intraocular fluid, the aqueous humour, in the trabecular meshwork is proposed in the paper. The model considers the meshwork as a circular ring with uniform thickness of homogeneous, isotropic, viscoelastic material swollen with continuously percolating aqueous humour. The mo...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02446710

    authors： Tandon PN,Autar R

    更新日期：1991-05-01 00:00:00

  • On-line monitoring of solutes in dialysate using wavelength-dependent absorption of ultraviolet radiation.

    abstract：:The aim of the study was to assess the wavelength dependence of the UV absorbance during monitoring of different compounds in the dialysate. UV absorbance was determined by using a double-beam spectrophotometer on dialysate samples taken at pre-determined times during dialysis, over a wavelength range of 180-380 nm. C...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02348430

    authors： Fridolin I,Lindberg LG

    更新日期：2003-05-01 00:00:00

  • A convolutional neural network-based learning approach to acute lymphoblastic leukaemia detection with automated feature extraction.

    abstract：:Leukaemia is a type of blood cancer which mainly occurs when bone marrow produces excess white blood cells in our body. This disease not only affects adult but also is a common cancer type among children. Treatment of leukaemia depends on its type and how far the disease has spread in the body. Leukaemia is classified...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-020-02282-x

    authors： Anwar S,Alam A

    更新日期：2020-12-01 00:00:00

  • Urinary bladder volume tracking using a Kalman filter.

    abstract：:This study introduced the Kalman filter procedure for tracking urinary bladder filling from intermittent bladder volume measurements taken by an ultrasonic bladder volume monitor. The Kalman filter was based on a double integrator as a model for the bladder filling process between micturitions and included a procedure...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02345809

    authors： Kristiansen NK,Sjöström SO,Nygaard H

    更新日期：2005-05-01 00:00:00

  • Pulsatile blood flow in total cavopulmonary connection: a comparison between Y-shaped and T-shaped geometry.

    abstract：:Single-ventricle anomaly is a hereditary heart disease that is characterized by anatomical malformations. The main consequence of this malformation is desaturated blood flow, which without proper treatment increases the risk of death. The classical treatment is based on a three-stage palliative procedure which should ...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-016-1499-4

    authors： Rajabzadeh-Oghaz H,Firoozabadi B,Saidi MS,Monjezi M,Navabi Shirazi MA,Malakan Rad E

    更新日期：2017-02-01 00:00:00

  • Left-ventricular pressure gradients: a computer-model simulation.

    abstract：:Both invasive left-ventricular pressure measurements and non-invasive colour M-mode echographic measurements have shown the existence of intraventricular pressure gradients (IVPGs) during early filling. The mechanisms responsible for these IVPG cannot be completely explained by the experiments. Therefore a one-dimensi...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02513338

    authors： Verdonck P,Vierendeels J,Riemslagh K,Dick E

    更新日期：1999-07-01 00:00:00

  • Real time monitoring and analysis via the medical information bus, Part II.

    abstract：:The complexity of the monitored data available in modern intensive care units suggests that they may be best processed, for presentation to medical staff, by expert system techniques. However, standard expert system shells are ill-fitted to either the basic sequential monitoring tasks of data acquisition and storage, ...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02525536

    authors： Taboada JA,Arcay B,Arias JE

    更新日期：1997-09-01 00:00:00

  • Effect of flow direction on the morphological responses of cultured bovine aortic endothelial cells.

    abstract：:The effect of flow direction on the morphology of cultured bovine aortic endothelial cells is studied. Fully confluent endothelial cells cultured on glass were subjected to a fluid-imposed shear stress of 2 Pa for 20 min and 24 h using a parallel plate flow chamber. Experiments on shear flow exposure were performed fo...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02522869

    authors： Kataoka N,Ujita S,Sato M

    更新日期：1998-01-01 00:00:00

  • Visualisation method of spatial interictal discharges in temporal epilepsy patients using magneto-encephalogram.

    abstract：:The aim of the study was to develop a method for investigating how interictal epileptic discharges in temporal epilepsy patients are activated spatially. The activity was measured using magneto-encephalography (MEG). The MEG data were used to produce a current-arrow map that reflected the topographic distribution of t...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02344215

    authors： Kandori A,Oe H,Miyashita K,Date H,Yamada N,Naritomi H,Chiba Y,Murakami M,Miyashita T,Tsukada K

    更新日期：2002-05-01 00:00:00

  • Arterial reservoir-excess pressure and ventricular work.

    abstract：:This study is based on the hypothesis that the pressure within the arterial network can be usefully decomposed as the sum of a reservoir pressure and an excess pressure. The reservoir pressure waveform is defined to be the same in each vessel but delayed by the wave travel time from the root of the aorta. Using calcul...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-012-0872-1

    authors： Parker KH,Alastruey J,Stan GB

    更新日期：2012-04-01 00:00:00

  • Velocity distribution model for normal blood flow in the human ascending aorta.

    abstract：:During the study of velocities in the human ascending aorta it became necessary to establish a method for two-dimensional velocity profiles from discrete velocity data obtained from different heartbeats and with different techniques. A descriptive geometrical model was therefore developed and expanded to 16 elements e...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02442319

    authors： Segadal L

    更新日期：1991-09-01 00:00:00

  • Methods of dynamic spectral analysis by self-exciting autoregressive moving average models and their application to analysing biosignals.

    abstract：:Dynamic methods in the spectral domain are necessary to analyse biological signals because of the frequently nonstationary character of the signals. The paper presents an adaptive procedure of fitting time-dependent ARMA models to nonstationary signals, which is suitable for on-line calculations. The properties of the...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02510536

    authors： Schack B,Bareshova E,Grieszbach G,Witte H

    更新日期：1995-05-01 00:00:00

  • CT-3D rotational angiography automatic registration: a sensitivity analysis.

    abstract：:Preprocessing, binning and dataset subsampling are investigated with regard to simultaneous maximisation of the speed, accuracy and robustness of CT-3D rotational angiography (3DRA) registration. Clinical diagnosis and treatment can both take advantage of this integration, because 3DRA allows the shape of vessel struc...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02351041

    authors： Stancanello J,Cavedon C,Francescon P,Cerveri P,Ferrigno G,Causin F,Colombo F

    更新日期：2005-09-01 00:00:00

  • Synergistic effects of local temperature enhancements on cellular responses in the context of high-intensity, ultrashort electric pulses.

    abstract：:Results of self-consistent analyses of cells show the possibility of temperature increases at membranes in response to a single nanosecond, high-voltage pulse, at least over small sections of the membrane. Molecular Dynamics simulations indicate that such a temperature increase could facilitate poration, which is one ...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-011-0745-z

    authors： Song J,Joshi RP,Schoenbach KH

    更新日期：2011-06-01 00:00:00

  • Multiregional viscoelastic characterization of the corona radiata in the sagittal plane of the porcine brain.

    abstract：:Detailed finite element (FE) models are used as promising tools to investigate traumatic brain injuries, although their accuracy is strongly dependent on the characterization of the mechanical behaviors of the different anatomic structures in the brain. In some cases, when the FE models require finer spatial resolutio...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-018-1891-3

    authors： Pan C,Chen F,Zhou J,Li X,Zhao F,Zhang X

    更新日期：2019-03-01 00:00:00

  • An atlas-based multimodal registration method for 2D images with discrepancy structures.

    abstract：:An atlas-based multimodal registration method for 2-dimension images with discrepancy structures was proposed in this paper. Atlas was utilized for complementing the discrepancy structure information in multimodal medical images. The scheme includes three steps: floating image to atlas registration, atlas to reference...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-018-1808-1

    authors： Lv W,Chen H,Peng Y,Li Y,Li J

    更新日期：2018-11-01 00:00:00

  • Application of genetic algorithms to parameter estimation of bioprocesses.

    abstract：:The paper explains the application of a genetic algorithm (GA) to the problem of estimating parameters for a kinetic model of a biologically reacting system. It is demonstrated that the GA is a powerful tool for quantifying the kinetic parameters using kinetic data. As the operation of the GA does not depend on the fo...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02510391

    authors： Park LJ,Park CH,Park C,Lee T

    更新日期：1997-01-01 00:00:00

  • Comparison between human awake, meditation and drowsiness EEG activities based on directed transfer function and MVDR coherence methods.

    abstract：:This study examined the electroencephalogram functional connectivity (coherence) and effective connectivity (flow of information) of selected brain regions during three different attentive states: awake, meditation and drowsiness. For the estimation of functional connectivity (coherence), Welch and minimum variance di...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-015-1272-0

    authors： Dissanayaka C,Ben-Simon E,Gruberger M,Maron-Katz A,Sharon H,Hendler T,Cvetkovic D

    更新日期：2015-07-01 00:00:00

  • Fast GPU-based computation of spatial multigrid multiframe LMEM for PET.

    abstract：:Significant efforts were invested during the last decade to accelerate PET list-mode reconstructions, notably with GPU devices. However, the computation time per event is still relatively long, and the list-mode efficiency on the GPU is well below the histogram-mode efficiency. Since list-mode data are not arranged in...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-015-1284-9

    authors： Nassiri MA,Carrier JF,Després P

    更新日期：2015-09-01 00:00:00

  • Estimating germinability of Plasmopara viticola oospores by means of neural networks.

    abstract：:Neural networks are trained to estimate the germination percentages of Plasmopara viticola oospores, overwintered in natural conditions in two viticultural areas in northern Italy, by using climatic (temperature and rainfall) data, as well as the previous germination measurement, as input variables. The 288 available ...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02344698

    authors： Vercesi A,Sirtori C,Vavassori A,Setti E,Liberati D

    更新日期：2000-01-01 00:00:00

  • Single motor unit analysis from spatially filtered surface electromyogram signals. Part 2: conduction velocity estimation.

    abstract：:The aim of the study was to compare experimentally conduction velocity (CV) estimates obtained with different estimation methods based on surface electromyogram (EMG) signals detected using five spatial filters. The filters investigated were the longitudinal single and double differential, transverse single and double...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02348440

    authors： Schulte E,Farina D,Rau G,Merletti R,Disselhorst-Klug C

    更新日期：2003-05-01 00:00:00

  • Prediction of persistence of combined evidence-based cardiovascular medications in patients with acute coronary syndrome after hospital discharge using neural networks.

    abstract：:In the PREVENIR-5 study, artificial neural networks (NN) were applied to a large sample of patients with recent first acute coronary syndrome (ACS) to identify determinants of persistence of evidence-based cardiovascular medications (EBCM: antithrombotic + beta-blocker + statin + angiotensin converting enzyme inhibito...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-011-0785-4

    authors： Bourdès V,Ferrières J,Amar J,Amelineau E,Bonnevay S,Berlion M,Danchin N

    更新日期：2011-08-01 00:00:00

  • Assessment of heart rate variability by application of central tendency measure.

    abstract：:The heart rate variability (HRV) is an indicator of the subject homeostasis alterations. For a healthy individual, the HRV shows a nonlinear behavior, thus requiring a nonlinear approach to provide additional information about HRV dynamics. In this work, the nonlinear techniques, central tendency measure (CTM) and sec...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-015-1390-8

    authors： dos Santos L,Barroso JJ,Macau EE,de Godoy MF

    更新日期：2015-11-01 00:00:00

  • Analysis of the first heart sound using the matching pursuit method.

    abstract：:It is acknowledged that the first heart sound S1 consists of two major, high-frequency components M1 and T1, corresponding, respectively, to the vibrations of the mitral and tricuspid valves and their surrounding tissues following valve closure in early systole. In this study, the matching pursuit (MP) method was used...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02345436

    authors： Wang W,Guo Z,Yang J,Zhang Y,Durand LG,Loew M

    更新日期：2001-11-01 00:00:00

  • Modelling and numerical simulation of the in vivo mechanical response of the ascending aortic aneurysm in Marfan syndrome.

    abstract：:Marfan syndrome (MFS) is a genetic disorder that affects connective tissue, impairing cardiovascular structures and function, such as heart valves and aorta. Thus, patients with Marfan disease have a higher risk of developing circulatory problems associated with mitral and aortic valves prolapse, manifested as dilated...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-016-1524-7

    authors： García-Herrera CM,Celentano DJ,Herrera EA

    更新日期：2017-03-01 00:00:00

  • Prediction of O-glycosylation sites based on multi-scale composition of amino acids and feature selection.

    abstract：:Protein glycosylation is one of the most important and complex post-translational modification that provides greater proteomic diversity than any other post-translational modification. Fast and reliable computational methods to identify glycosylation sites are in great demand. Two key issues, feature encoding and feat...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-015-1268-9

    authors： Chen Y,Zhou W,Wang H,Yuan Z

    更新日期：2015-06-01 00:00:00