Molecular and cytological analysis of widely-used Gal4 driver lines for Drosophila neurobiology.

abstract：BACKGROUND:Koala (Koa) is a dominant mutation in mice causing bushy muzzle and pinna, and is associated with a chromosomal inversion on the distal half of chromosome 15. To identify the gene responsible for the Koa phenotypes, we investigated phenotypes of Koa homozygous mice and determined the breakpoints of the inver...

journal_title：BMC genetics

authors： Katayama K,Miyamoto S,Furuno A,Akiyama K,Takahashi S,Suzuki H,Tsuji T,Kunieda T

更新日期：2009-09-22 00:00:00

abstract：BACKGROUND:Although harness racing is of high economic importance to the global equine industry, significant genomic resources have yet to be applied to mapping harness racing success. To identify genomic regions associated with harness racing success, the current study performs genome-wide association analyses with th...

journal_title：BMC genetics

authors： Velie BD,Fegraeus KJ,Solé M,Rosengren MK,Røed KH,Ihler CF,Strand E,Lindgren G

更新日期：2018-08-29 00:00:00

abstract：BACKGROUND:The spotted-wing Drosophila (Drosophila suzukii) is a widespread invasive pest that causes severe economic damage to fruit crops. The early development of D. suzukii is similar to that of other Drosophilids, but the roles of individual genes must be confirmed experimentally. Cellularization genes coordinate ...

journal_title：BMC genetics

authors： Yan Y,Jaffri SA,Schwirz J,Stein C,Schetelig MF

更新日期：2020-12-18 00:00:00

abstract：BACKGROUND:Genomic information can be used to predict not only continuous but also categorical (e.g. binomial) traits. Several traits of interest in human medicine and agriculture present a discrete distribution of phenotypes (e.g. disease status). Root vigor in sugar beet (B. vulgaris) is an example of binomial trait ...

journal_title：BMC genetics

authors： Biscarini F,Stevanato P,Broccanello C,Stella A,Saccomani M

更新日期：2014-07-22 00:00:00

abstract：BACKGROUND:Single-nucleotide polymorphisms (SNPs) in microRNAs (miRNAs) and their target binding sites affect miRNA function and are involved in biological processes and diseases, including bovine mastitis, a frequent inflammatory disease. Our previous study has shown that bta-miR-2899 is significantly upregulated in t...

journal_title：BMC genetics

authors： Jiang Q,Zhao H,Li R,Zhang Y,Liu Y,Wang J,Wang X,Ju Z,Liu W,Hou M,Huang J

更新日期：2019-05-16 00:00:00

abstract：BACKGROUND:Myanmar cattle populations predominantly consist of native cattle breeds (Pyer Sein and Shwe), characterized by their geographical location and coat color, and the Holstein-Friesian crossbreed, which is highly adapted to the harsh tropical climates of this region. Here, we analyzed the diversity and genetic ...

journal_title：BMC genetics

authors： Giovambattista G,Moe KK,Polat M,Borjigin L,Hein ST,Moe HH,Takeshima SN,Aida Y

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Acipenseriformes is a basal lineage of ray-finned fishes and comprise 27 extant species of sturgeons and paddlefishes. They are characterized by several specific genomic features as broad ploidy variation, high chromosome numbers, presence of numerous microchromosomes and propensity to interspecific hybridiz...

journal_title：BMC genetics

authors： Symonová R,Havelka M,Amemiya CT,Howell WM,Kořínková T,Flajšhans M,Gela D,Ráb P

更新日期：2017-03-02 00:00:00

abstract：BACKGROUND:Genetic maps based on single-nucleotide polymorphisms (SNP) are increasingly being used as an alternative to microsatellite maps. This study compares linkage results for both types of maps for a neurophysiology phenotype and for an alcohol dependence phenotype. Our analysis used two SNP maps on the Illumina ...

journal_title：BMC genetics

authors： Dunn G,Hinrichs AL,Bertelsen S,Jin CH,Kauwe JS,Suarez BK,Bierut LJ

更新日期：2005-12-30 00:00:00

abstract：BACKGROUND:Spotted wilt caused by tomato spotted wilt virus (TSWV) is one of the major peanut (Arachis hypogaea L.) diseases in the southeastern United States. Occurrence, severity, and symptoms of spotted wilt disease are highly variable from season to season, making it difficult to efficiently evaluate breeding popul...

journal_title：BMC genetics

authors： Tseng YC,Tillman BL,Peng Z,Wang J

更新日期：2016-09-06 00:00:00

abstract：BACKGROUND:Genome-wide association studies involve detecting association between millions of genetic variants and a trait, which typically use univariate regression to test association between each single variant and the phenotype. Alternatively, Lasso penalized regression allows one to jointly model the relationship b...

journal_title：BMC genetics

authors： Arbet J,McGue M,Chatterjee S,Basu S

更新日期：2017-07-24 00:00:00

abstract：BACKGROUND:Non-invasive sampling has opened avenues for the genetic study of elusive species, which has contributed significantly to their conservation. Where field based identity of non-invasive sample is ambiguous (e.g. carnivore scats), it is essential to establish identity of the species through molecular approache...

journal_title：BMC genetics

authors： Maroju PA,Yadav S,Kolipakam V,Singh S,Qureshi Q,Jhala Y

更新日期：2016-02-09 00:00:00

abstract：BACKGROUND:There are at least 25 human selenoproteins, each characterized by the incorporation of selenium into the primary sequence as the amino acid selenocysteine. Since many selenoproteins have antioxidant properties, it is plausible that inter-individual differences in selenoprotein expression or activity could in...

journal_title：BMC genetics

authors： Foster CB,Aswath K,Chanock SJ,McKay HF,Peters U

更新日期：2006-12-11 00:00:00

abstract：BACKGROUND:Despite several thousands of years of close contacts, there are genetic differences between the neighbouring countries of Finland and Sweden. Within Finland, signs of an east-west duality have been observed, whereas the population structure within Sweden has been suggested to be more subtle. With a fine-scal...

journal_title：BMC genetics

authors： Hannelius U,Salmela E,Lappalainen T,Guillot G,Lindgren CM,von Döbeln U,Lahermo P,Kere J

更新日期：2008-08-19 00:00:00

abstract：BACKGROUND:Selection for grain yield under drought is an efficient criterion for improving the drought tolerance of rice. Recently, some drought-tolerant rice varieties have been developed using this selection criterion and successfully released for cultivation in drought-prone target environments. The process can be m...

journal_title：BMC genetics

authors： Mishra KK,Vikram P,Yadaw RB,Swamy BP,Dixit S,Cruz MT,Maturan P,Marker S,Kumar A

更新日期：2013-02-26 00:00:00

abstract：BACKGROUND:MUC4 is a type of membrane anchored glycoprotein and serves as the major constituent of mucus that covers epithelial surfaces of many tissues such as trachea, colon and cervix. MUC4 plays important roles in the lubrication and protection of the surface epithelium, cell proliferation and differentiation, immu...

journal_title：BMC genetics

authors： Yang M,Yang B,Yan X,Ouyang J,Zeng W,Ai H,Ren J,Huang L

更新日期：2012-07-13 00:00:00

abstract：BACKGROUND:Hu sheep, a unique Chinese breed with high reproductive performance, are also well known for their rare white lambskin in China. The quality of lambskin is affected by hair follicles, and dermal papilla cells are an important component of hair follicles that plays a key role in hair follicle growth and devel...

journal_title：BMC genetics

authors： Lv X,Gao W,Jin C,Wang L,Wang Y,Chen W,Zou S,Huang S,Li Z,Wang J,Sun W

更新日期：2019-08-27 00:00:00

abstract：BACKGROUND:Epidemiological studies have indicated that obesity and low high-density lipoprotein (HDL) levels are strong cardiovascular risk factors, and that these traits are inversely correlated. Despite the belief that these traits are correlated in part due to pleiotropy, knowledge on specific genes commonly affecti...

journal_title：BMC genetics

authors： Arya R,Lehman D,Hunt KJ,Schneider J,Almasy L,Blangero J,Stern MP,Duggirala R,Framingham Heart Study.

更新日期：2003-12-31 00:00:00

abstract：BACKGROUND:Monogenic diabetes is a genetic disease often caused by mutations in genes involved in beta-cell function. Correct sub-categorization of the disease is a prerequisite for appropriate treatment and genetic counseling. Target-region capture sequencing is a combination of genomic region enrichment and next gene...

journal_title：BMC genetics

authors： Gao R,Liu Y,Gjesing AP,Hollensted M,Wan X,He S,Pedersen O,Yi X,Wang J,Hansen T

更新日期：2014-01-29 00:00:00

abstract：BACKGROUND:We previously conducted a genome-wide association study (GWAS) strategy for milk fatty acids in Chinese Holstein, and identified 83 genome-wide significant single nucleotide polymorphisms (SNPs) and 314 suggestive significant SNPs. Among them, two SNPs, BTB-01077939 and BTA-11275-no-rs associated with C10:0,...

journal_title：BMC genetics

authors： Shi L,Lv X,Liu L,Yang Y,Ma Z,Han B,Sun D

更新日期：2019-07-03 00:00:00

abstract：BACKGROUND:DNA methylation is an epigenetic modification that mainly repress expression of genes essential during embryogenesis and development. There are key ATPase-dependent enzymes that read or write DNA methylation to remodel chromatin and regulate gene expression. Structural maintenance of chromosome hinge domain ...

journal_title：BMC genetics

authors： Massah S,Jubene J,Lee FJS,Beischlag TV,Prefontaine GG

更新日期：2020-01-15 00:00:00

abstract：BACKGROUND:Genetic maps characterizing the inheritance patterns of traits and markers have been developed for a wide range of species and used to study questions in biomedicine, agriculture, ecology and evolutionary biology. The status of rainbow trout genetic maps has progressed significantly over the last decade due ...

journal_title：BMC genetics

authors： Rexroad CE 3rd,Palti Y,Gahr SA,Vallejo RL

更新日期：2008-11-19 00:00:00

abstract：BACKGROUND:DGAT2 is a promising candidate gene for obesity because of its function as a key enzyme in fat metabolism and because of its localization on chromosome 11q13, a linkage region for extreme early onset obesity detected in our sample. We performed a mutation screen in 93 extremely obese children and adolescents...

journal_title：BMC genetics

authors： Friedel S,Reichwald K,Scherag A,Brumm H,Wermter AK,Fries HR,Koberwitz K,Wabitsch M,Meitinger T,Platzer M,Biebermann H,Hinney A,Hebebrand J

更新日期：2007-05-03 00:00:00

abstract：BACKGROUND:Somatolactin alpha (SLa) is a fish-specific peptide hormone secreted from the pituitary. In medaka, SLa functions to darken the skin color and lack of SLa makes it pale. Transcription of SLa is enhanced or suppressed when fish are kept in dark or bright conditions, respectively, indicating SLa's important ro...

journal_title：BMC genetics

authors： Sasano Y,Yoshimura A,Fukamachi S

更新日期：2012-07-24 00:00:00

abstract：BACKGROUND:In this article, I propose a model-selection-free method to map multiple quantitative trait loci (QTL) in variance component model, which is useful in outbred populations. The new method can estimate the variance of zero-effect QTL infinitely to zero, but nearly unbiased for non-zero-effect QTL. It is analog...

journal_title：BMC genetics

authors： Fang M

更新日期：2010-04-29 00:00:00

abstract：BACKGROUND:Relationships between individuals and inbreeding coefficients are commonly used for breeding decisions, but may be affected by the type of data used for their estimation. The proportion of variants with low Minor Allele Frequency (MAF) is larger in whole genome sequence (WGS) data compared to Single Nucleoti...

journal_title：BMC genetics

authors： Eynard SE,Windig JJ,Leroy G,van Binsbergen R,Calus MP

更新日期：2015-03-12 00:00:00

abstract：BACKGROUND:The establishment of the bisexual fertile fish hybrid lineage including the allodiploid and allotetraploid hybrids, from interspecific hybridization of red crucian carp (Carassius auratus red var. 2n = 100, 2n = AA) (♀) × common carp (Cyprinus carpio L. 2n = 100, 2n = BB) (♂), provided a good platform to inv...

journal_title：BMC genetics

authors： Zhang C,Ye L,Chen Y,Xiao J,Wu Y,Tao M,Xiao Y,Liu S

更新日期：2015-12-03 00:00:00

abstract：BACKGROUND:Reniform nematode (Rotylenchulus reniformis) has emerged as one of the most destructive root pathogens of upland cotton (Gossypium hirsutum) in the United States. Management of R. reniformis has been hindered by the lack of resistant G. hirsutum cultivars; however, resistance has been frequently identified i...

journal_title：BMC genetics

authors： Li R,Erpelding JE,Stetina SR

更新日期：2018-08-03 00:00:00

abstract：BACKGROUND:Tumor suppressor gene p53 plays an important role in the maintenance of the genomic integrity, and mutation in the gene may alter an individual's susceptibility to various carcinomas. P53 Arg72Pro or codon 72 polymorphism has been indicated to increase the risk of developing certain cancers such as bladder c...

journal_title：BMC genetics

authors： Hou J,Gu Y,Hou W,Wu S,Lou Y,Yang W,Zhu L,Hu Y,Sun M,Xue H

更新日期：2015-06-30 00:00:00

abstract：BACKGROUND:Drought is one of the most important abiotic stresses causing drastic reductions in yield in rainfed rice environments. The suitability of grain yield (GY) under drought as a selection criterion has been reported in the past few years. Most of the quantitative trait loci (QTLs) for GY under drought in rice r...

journal_title：BMC genetics

authors： Vikram P,Swamy BP,Dixit S,Ahmed HU,Teresa Sta Cruz M,Singh AK,Kumar A

更新日期：2011-10-18 00:00:00

abstract：BACKGROUND:Hip dysplasia remains one of the most serious hereditary diseases occurring in dogs despite long-standing evaluation schemes designed to aid selection for healthy joints. Many researchers have recommended the use of estimated breeding values (EBV) to improve the rate of genetic progress from selection agains...

journal_title：BMC genetics

authors： Lewis TW,Blott SC,Woolliams JA

更新日期：2013-03-02 00:00:00