Motion of the residual femur within the socket during gait is associated with patient-reported problems in transfemoral amputees.

Abstract:

:The purpose of this study was to provide a quantitative description of residual femur motion within the socket during gait and to explore the relationship between residual femur motion and patient-reported comfort and function. It was hypothesized that increased residual bone movement would correlate to worse patient-reported comfort and function. The secondary goals were to assess within-subject step-to-step variability and between-subject variability in residual femur motion within the socket during gait. Dynamic biplane radiography, combined with conventional motion capture, was used to measure residual femur motion within the socket during treadmill walking for 10 unilateral transfemoral amputees. The questionnaire for persons with a transfemoral amputation (Q-TFA) was administered to assess prosthetic use, mobility, health problems, and global health. Increased femur pistoning (proximal-distal translation relative to the socket) correlated with worsening Q-TFA problem and global scores (ρ = 0.741, p = 0.04 and ρ = -0.783, p = 0.02, respectively). Average residual femur rotation ROMs were 7.3°±3.7°, 10.8°±4.4°, and 7.7°±4.8° for anterior tilt, internal-external rotation, and varus-valgus, respectively. Average residual femur translation ROMs were 8.6 mm ± 3.0 mm, 28.4 mm ± 13.9 mm, and 20.4 mm ± 7.2 mm for medial-lateral, pistoning, and anterior-posterior directions, respectively. Within-subject rotational and translational variability during gait averaged 2.8° and 2.0 mm or less, whereas the between-subject variability was up to 9.4° and 18.6 mm, which demonstrates residual femur motion relative to the socket is repeatable within subjects, but inconsistent across subjects during gait. The results suggest residual bone motion within the socket is a potential mechanism behind patient-reported problems and suggests a target for intervention aimed at improving transfemoral amputee quality of life.

journal_name

J Biomech

journal_title

Journal of biomechanics

authors

Gale T,Yang S,McGough R,Fiedler G,Anderst W

doi

10.1016/j.jbiomech.2020.110050

subject

Has Abstract

pub_date

2020-11-09 00:00:00

pages

110050

eissn

0021-9290

issn

1873-2380

pii

S0021-9290(20)30474-7

journal_volume

112

pub_type

杂志文章
  • The three-dimensional determination of internal loads in the lower extremity.

    abstract::A three-dimensional model of the lower limb containing 47 muscles was developed to study the differences between a two- and three-dimensional approach for determining internal loads, the role of the dynamic joint representation, and the behavior of different load-bearing criteria in walking and running. The problem of...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(97)00089-4

    authors: Glitsch U,Baumann W

    更新日期:1997-11-01 00:00:00

  • Expedited patient-specific assessment of contact stress exposure in the ankle joint following definitive articular fracture reduction.

    abstract::Acute injury severity, altered joint kinematics, and joint incongruity are three important mechanical factors linked to post-traumatic osteoarthritis (PTOA). Finite element analysis (FEA) was previously used to assess the influence of increased contact stress due to joint incongruity on PTOA development. While promisi...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.05.030

    authors: Kern AM,Anderson DD

    更新日期:2015-09-18 00:00:00

  • Micro-CT and micro-FE analysis of pedicle screw fixation under different loading conditions.

    abstract::Anchorage of pedicle screw instrumentation in the elderly spine with poor bone quality remains challenging. In this study, micro finite element (µFE) models were used to assess the specific influence of screw design and the relative contribution of local bone density to fixation mechanics. These were created from micr...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2017.12.023

    authors: Chevalier Y,Matsuura M,Krüger S,Fleege C,Rickert M,Rauschmann M,Schilling C

    更新日期:2018-03-21 00:00:00

  • Numerical simulation of unsteady laminar flow through a tilting disk heart valve: prediction of vortex shedding.

    abstract::Heart valves induce flow disturbances which play a role in blood cell activation and damage, but questions of the magnitude and spatial distribution of fluid stresses (wall shear stress and turbulent stress) cannot be readily addressed with current experimental techniques. Therefore, a numerical simulation procedure f...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(94)90015-9

    authors: Huang ZJ,Merkle CL,Abdallah S,Tarbell JM

    更新日期:1994-04-01 00:00:00

  • Effect of cracks on the local deformations of articular cartilage.

    abstract::Despite significant evidence regarding the increased risk of cartilage degeneration due to traumatic injuries to joints, there is still a lack of understanding of the mechanisms underlying osteoarthritis development following a joint injury. Injuries in knee cartilage are often characterized by lesions or tears. In ad...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2020.109970

    authors: Komeili A,Luqman S,Federico S,Herzog W

    更新日期:2020-09-18 00:00:00

  • Fluid pressures at the shoe-floor-contaminant interface during slips: effects of tread and implications on slip severity.

    abstract::Previous research on slip and fall accidents has suggested that pressurized fluid between the shoe and floor is responsible for initiating slips yet this effect has not been verified experimentally. This study aimed to (1) measure hydrodynamic pressures during slipping for treaded and untreaded conditions; (2) determi...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jbiomech.2013.10.046

    authors: Beschorner KE,Albert DL,Chambers AJ,Redfern MS

    更新日期:2014-01-22 00:00:00

  • An activatable molecular spring reduces muscle tearing during extreme stretching.

    abstract::The purpose of this study was to determine failure stresses and failure lengths of actively and passively stretched myofibrils. As expected, myofibrils failed at average sarcomere lengths (about 6-7μm) that vastly exceeded sarcomere lengths at which actin-myosin filament overlap ceases to exist (4μm) and thus actin-my...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2010.07.016

    authors: Leonard TR,Joumaa V,Herzog W

    更新日期:2010-11-16 00:00:00

  • Orofacial and thumb-index finger ramp-and-hold isometric force dynamics in young neurotypical adults.

    abstract::The relation among several parameters of the ramp-and-hold isometric force contraction (peak force and dF/dtmax during the initial phase of force recruitment, and the proportion of hold-phase at target) was quantified for the right and left thumb-index finger pinch, and lower lip midline compression in 40 neurotypical...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2018.02.031

    authors: Barlow SM,Hozan M,Lee J,Greenwood J,Custead R,Wardyn B,Tippin K

    更新日期:2018-04-27 00:00:00

  • Skewness angle of interfibrillar proteoglycans increases with applied load on mitral valve chordae tendineae.

    abstract::In highly aligned connective tissues, such as tendon, collagen fibrils are linked together by proteoglycans (PGs). Recent mechanical and theoretical studies on tendon micromechanics have implied that PGs mediate mechanical interactions between adjacent collagen fibrils. We used transmission electron microscopy to obse...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2005.12.011

    authors: Liao J,Vesely I

    更新日期:2007-01-01 00:00:00

  • Immobilization of the rabbit tibialis anterior muscle in a lengthened position causes addition of sarcomeres in series and extra-cellular matrix proliferation.

    abstract::Rabbits were immobilized for 3 weeks with the ankle in plantar flexion, midrange position or dorsal extension (n=15). The left leg was used as control. Sarcomere lengths were measured by laser diffraction in vivo in the tibialis anterior (TA) muscle. Legs immobilized in the midrange position showed coherent diffractio...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2008.03.006

    authors: Pontén E,Fridén J

    更新日期:2008-01-01 00:00:00

  • Blood and interstitial flow in the hierarchical pore space architecture of bone tissue.

    abstract::There are two main types of fluid in bone tissue, blood and interstitial fluid. The chemical composition of these fluids varies with time and location in bone. Blood arrives through the arterial system containing oxygen and other nutrients and the blood components depart via the venous system containing less oxygen an...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2014.12.013

    authors: Cowin SC,Cardoso L

    更新日期:2015-03-18 00:00:00

  • Evaluation of left ventricular function based on simulated systolic flow dynamics computed from regional wall motion.

    abstract::Left ventricular (LV) chamber flow is undoubtedly influenced by the time-dependent regional motion of the LV wall. In an attempt to obtain diagnostic parameters based on LV chamber flow, we computed the LV chamber, two-dimensional systolic velocity and pressure distribution for two right anterior oblique (RAO) ventric...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(94)90201-1

    authors: Schoephoerster RT,Silva CL,Ray G

    更新日期:1994-02-01 00:00:00

  • Stress deprivation from the patellar tendon induces apoptosis of fibroblasts in vivo with activation of mitogen-activated protein kinases.

    abstract::The effect of stress deprivation on the tendon tissue has been an important focus in the field of biomechanics. However, less is known about the in vivo effect of stress deprivation on fibroblast apoptosis as of yet. This study was conducted to test a hypothesis that complete stress deprivation of the patellar tendon ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2009.07.027

    authors: Kawabata H,Katsura T,Kondo E,Kitamura N,Miyatake S,Tanabe Y,Setoguchi T,Komiya S,Yasuda K

    更新日期:2009-11-13 00:00:00

  • Effect of wedging on the flow characteristics past tilting disc aortic valve prosthesis.

    abstract::To evaluate the efficacy of implanting a tilting disc aortic valve prosthesis in an angulated (wedged) supra-annular position, an in vitro experimental study was performed. The aortic valve prosthesis was mounted in an axi-symmetric valve chamber in a wedged position and incorporated in a mock circulatory system. Meas...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(86)90150-8

    authors: Chandran KB,Fatemi R,Hiratzka LF,Harris C

    更新日期:1986-01-01 00:00:00

  • Computational reverse shoulder prosthesis model: Experimental data and verification.

    abstract::The reverse shoulder prosthesis aims to restore the stability and function of pathological shoulders, but the biomechanical aspects of the geometrical changes induced by the implant are yet to be fully understood. Considering a large-scale musculoskeletal model of the upper limb, the aim of this study is to evaluate h...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.06.031

    authors: Martins A,Quental C,Folgado J,Ambrósio J,Monteiro J,Sarmento M

    更新日期:2015-09-18 00:00:00

  • Uncertainty quantification of wall shear stress in intracranial aneurysms using a data-driven statistical model of systemic blood flow variability.

    abstract::Adverse wall shear stress (WSS) patterns are known to play a key role in the localisation, formation, and progression of intracranial aneurysms (IAs). Complex region-specific and time-varying aneurysmal WSS patterns depend both on vascular morphology as well as on variable systemic flow conditions. Computational fluid...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2016.10.005

    authors: Sarrami-Foroushani A,Lassila T,Gooya A,Geers AJ,Frangi AF

    更新日期:2016-12-08 00:00:00

  • Microcrack growth parameters for compact bone deduced from stiffness variations.

    abstract::This paper shows how information on the fatigue behaviour of microcracks can be obtained by the analysis of stiffness changes measured during cyclic loading. Relationships between crack length, growth rate and cyclic stress intensity were deduced, and compared with previous empirical equations. Results show that the c...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(98)00050-5

    authors: Taylor D

    更新日期:1998-07-01 00:00:00

  • Estimation of musculotendon parameters for scaled and subject specific musculoskeletal models using an optimization technique.

    abstract::A challenging aspect of subject specific musculoskeletal modeling is the estimation of muscle parameters, especially optimal fiber length and tendon slack length. In this study, the method for scaling musculotendon parameters published by Winby et al. (2008), J. Biomech. 41, 1682-1688, has been reformulated, generaliz...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.11.006

    authors: Modenese L,Ceseracciu E,Reggiani M,Lloyd DG

    更新日期:2016-01-25 00:00:00

  • Velocities and stress levels of axisymmetric, azimuthal flow within the toroidal rotary seal of the IBM 2997 continuous flow cell separator and the implications.

    abstract::Continuous flow blood fraction separators are used to facilitate the removal of specific blood components for donation or for certain medical procedures. Problems with one such device, the IBM 2997 Blood Processor, have been noted in a number of independent investigations. A key feature of this particular unit is a ce...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(86)90163-6

    authors: Harvey CB,O'Rear EA

    更新日期:1986-01-01 00:00:00

  • Three-dimensional tissue deformation in subcutaneous tissues overlying bony prominences may help to explain external load transfer to the interstitium.

    abstract::Anesthetized, carefully positioned, female, weanling, white-haired pigs were used to test the hypothesis that (1) interface pressure, the pressure between the skin and an external load, can be used to predict the interstitial fluid pressure over the wings of ilia and the last dorsal spinous process and (2) three-dimen...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(91)90322-e

    authors: Dodd KT,Gross DR

    更新日期:1991-01-01 00:00:00

  • A force plate study of avian gait.

    abstract:OBJECTIVE:To test the force plate as a gait analysis system for broilers and to determine how the ground reaction force (GRF) patterns change in these birds with growth and administration of analgesia. MATERIALS AND METHODS:Thirty-three male Ross 308 chicks were raised on either an ad libitum or restricted-feeding reg...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2006.09.014

    authors: Corr SA,McCorquodale C,McDonald J,Gentle M,McGovern R

    更新日期:2007-01-01 00:00:00

  • The influence of ligament modelling strategies on the predictive capability of finite element models of the human knee joint.

    abstract::In finite element (FE) models knee ligaments can represented either by a group of one-dimensional springs, or by three-dimensional continuum elements based on segmentations. Continuum models closer approximate the anatomy, and facilitate ligament wrapping, while spring models are computationally less expensive. The me...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2017.08.030

    authors: Naghibi Beidokhti H,Janssen D,van de Groes S,Hazrati J,Van den Boogaard T,Verdonschot N

    更新日期:2017-12-08 00:00:00

  • Directional dependence of hydroxyapatite-collagen interactions on mechanics of collagen.

    abstract::Bone is a biological nanocomposite composed primarily of collagen and hydroxyapatite. The collagen molecules self-assemble to from a structure known as a fibril that comprises of about 85-95% of the total bone protein. In a fibril, the molecular level interactions at the interface between molecular collagen and hydrox...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2010.02.027

    authors: Katti DR,Pradhan SM,Katti KS

    更新日期:2010-06-18 00:00:00

  • Shoe midsole hardness, sex and age effects on lower extremity kinematics during running.

    abstract::Previous studies investigating the effects of shoe midsole hardness on running kinematics have often used male subjects from within a narrow age range. It is unknown whether shoe midsole hardness has the same kinematic effect on male and female runners as well as runners from different age categories. As sex and age h...

    journal_title:Journal of biomechanics

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jbiomech.2012.03.027

    authors: Nigg BM,Baltich J,Maurer C,Federolf P

    更新日期:2012-06-01 00:00:00

  • Influence of muscle anatomical cross-sectional area on the moment arm length of the triceps brachii muscle at the elbow joint.

    abstract::The purpose of this study was to test the hypothesis that the musculotendon moment arm length is affected by the muscle anatomical cross-sectional area. The moment arm length of the triceps brachii (TB) muscle at 30°, 50°, 70°, 90°, 110° elbow flexion positions was measured in sagittal magnetic resonance images (MRI) ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2010.06.013

    authors: Sugisaki N,Wakahara T,Miyamoto N,Murata K,Kanehisa H,Kawakami Y,Fukunaga T

    更新日期:2010-10-19 00:00:00

  • Effect of high altitude exposure on the hemodynamics of the bidirectional Glenn physiology: modeling incremented pulmonary vascular resistance and heart rate.

    abstract::The considerable blood mixing in the bidirectional Glenn (BDG) physiology further limits the capacity of the single working ventricle to pump enough oxygenated blood to the circulatory system. This condition is exacerbated under severe conditions such as physical activity or high altitude. In this study, the effect of...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2014.03.021

    authors: Vallecilla C,Khiabani RH,Sandoval N,Fogel M,Briceño JC,Yoganathan AP

    更新日期:2014-06-03 00:00:00

  • Physical properties of resistance vessel wall in peripheral blood flow regulation--I. Mathematical model.

    abstract::A mathematical model is introduced to investigate the influence of the physical properties of the resistance vessel wall on the metabolic and myogenic mechanisms. The resistance vessel wall is assumed to have an elastic property and the elastic modulus to be a function of pressure (myogenic) and flow (metabolic). Bloo...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(89)90033-x

    authors: Iida N

    更新日期:1989-01-01 00:00:00

  • Adversarial autoencoder for visualization and classification of human activity: Application to a low-cost commercial force plate.

    abstract::The ability to visualize and interpret high dimensional time-series data will be critical as wearable and other sensors are adopted in rehabilitation protocols. This study proposes a latent space representation of high dimensional time-series data for data visualization. For that purpose, a deep learning model called ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2020.109684

    authors: Hernandez V,Kulić D,Venture G

    更新日期:2020-04-16 00:00:00

  • A constitutive model for vascular tissue that integrates fibril, fiber and continuum levels with application to the isotropic and passive properties of the infrarenal aorta.

    abstract::A fundamental understanding of the mechanical properties of the extracellular matrix (ECM) is critically important to quantify the amount of macroscopic stress and/or strain transmitted to the cellular level of vascular tissue. Structural constitutive models integrate histological and mechanical information, and hence...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2011.07.015

    authors: Martufi G,Gasser TC

    更新日期:2011-09-23 00:00:00

  • Effect of scaffold material, construct length and mechanical stimulation on the in vitro stiffness of the engineered tendon construct.

    abstract::Introducing mesenchymal stem cell (MSC)-seeded collagen constructs into load-protected wound sites in the rabbit patellar and Achilles tendons significantly improves their repair outcome compared to natural healing of the unfilled defect. However, these constructs would not be acceptable alternatives for repairing com...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2007.11.009

    authors: Nirmalanandhan VS,Rao M,Shearn JT,Juncosa-Melvin N,Gooch C,Butler DL

    更新日期:2008-01-01 00:00:00