Coronary micro-computed tomography angiography in mice.

abstract：:YidC, a bacterial member of the YidC/Alb3/Oxa1 insertase family, mediates membrane protein assembly and insertion. Cytoplasmic loops are known to have functional significance in membrane proteins such as YidC. Employing microsecond-level molecular dynamics (MD) simulations, we show that the crystallographically unreso...

journal_title：Scientific reports

authors： Harkey T,Govind Kumar V,Hettige J,Tabari SH,Immadisetty K,Moradi M

更新日期：2019-10-08 00:00:00

abstract：:Activation of the inflammasome is involved in the progression of retinal degenerative diseases, in particular, in the pathogenesis of Age-Related Macular Degeneration (AMD), with NLRP3 activation the focus of many investigations. In this study, we used genetic and pharmacological approaches to explore the role of the ...

journal_title：Scientific reports

authors： Wooff Y,Fernando N,Wong JHC,Dietrich C,Aggio-Bruce R,Chu-Tan JA,Robertson AAB,Doyle SL,Man SM,Natoli R

更新日期：2020-02-10 00:00:00

abstract：:Continuous, as opposed to pulsatile, delivery of hypothalamic gonadotropin-releasing hormone (GnRH) leads to a marked decrease in secretion of pituitary gonadotropins LH and FSH and impairment of reproductive function. Here we studied the expression profile of gonadotropin subunit and GnRH receptor genes in rat pituit...

journal_title：Scientific reports

authors： Janjic MM,Prévide RM,Fletcher PA,Sherman A,Smiljanic K,Abebe D,Bjelobaba I,Stojilkovic SS

更新日期：2019-12-27 00:00:00

abstract：:Because of ubiquity of thioesters, thioesterases play a critical role in metabolism, membrane biosynthesis, signal transduction, and gene regulation. In many bacteria, YbgC is such an enzyme, whose coding gene mostly resides in the tol-pal cluster. Although all other proteins encoded in the tol-pal cluster are clearly...

journal_title：Scientific reports

authors： Gao T,Meng Q,Gao H

更新日期：2017-06-21 00:00:00

abstract：:As an analytic pipeline for quantitative imaging feature extraction and analysis, radiomics has grown rapidly in the past decade. On the other hand, recent advances in deep learning and transfer learning have shown significant potential in the quantitative medical imaging field, raising the research question of whethe...

journal_title：Scientific reports

authors： Zhang Y,Lobo-Mueller EM,Karanicolas P,Gallinger S,Haider MA,Khalvati F

更新日期：2021-01-14 00:00:00

abstract：:The mechanisms underlying bladder contractile disorders such as overactive bladder are not fully understood, and there is limited understanding of the receptor systems modulating spontaneous bladder contractions. We investigated the potential for histamine to have a role in mediating contractility of the urothelium wi...

journal_title：Scientific reports

authors： Stromberga Z,Chess-Williams R,Moro C

更新日期：2019-03-07 00:00:00

abstract：:The arrival of Neolithic culture in North Africa, especially domestic animals has been essentially documented from archaeological records. As the data relative to sheep are scarce, we studied the genetic relationship between Moroccan sheep breeds and Mediterranean ones using the sequencing of 628 bp of the mitochondri...

journal_title：Scientific reports

authors： Kandoussi A,Boujenane I,Auger C,Serranito B,Germot A,Piro M,Maftah A,Badaoui B,Petit D

更新日期：2020-06-23 00:00:00

abstract：:A pancreatic β-cell line MIN6 was previously established in our lab from an insulinoma developed in an IT6 transgenic mouse expressing the SV40 T antigen in β-cells. This cell line has been widely used for in vitro analysis of β-cell function, but tends to lose the mature β-cell features, including glucose-stimulated ...

journal_title：Scientific reports

authors： Miyazaki S,Tashiro F,Tsuchiya T,Sasaki K,Miyazaki JI

更新日期：2021-01-12 00:00:00

abstract：:Diffraction gratings are an essential optical component of high-power, short-pulse lasers. The maximum output of high-power pulsed lasers is always determined by laser resistance of gratings and this resistance is strongly dependent on the local near electric field intensity in the grating structure. We presented a no...

journal_title：Scientific reports

authors： Chen J,Huang H,Zhang Y,Wang Y,Kong F,Wang Y,Jin Y,Chen P,Xu J,Shao J

更新日期：2018-03-27 00:00:00

abstract：:The present study reports the use of one-dimensional carbon wrapped VO2(M) nanofiber (VO2(M)/C) as a cost-effective counter electrode for dye-sensitized solar cells (DSSCs); where M denotes monoclinic crystal system. Uniform short length nanofiber was synthesised by a sol-gel based simple and versatile electrospinning...

journal_title：Scientific reports

authors： Gnanasekar S,Kollu P,Jeong SK,Grace AN

更新日期：2019-03-26 00:00:00

abstract：:Bile acid (BA) signatures are altered in many disease states. BA metabolism is an important microbial function to assist gut colonization and persistence, as well as microbial survival during gastro intestinal (GI) transit and it is an important criteria for potential probiotic bacteria. Microbes that express bile sal...

journal_title：Scientific reports

authors： Prete R,Long SL,Gallardo AL,Gahan CG,Corsetti A,Joyce SA

更新日期：2020-01-24 00:00:00

abstract：:The maternal environment can influence the intensity of seed dormancy and thus seasonal germination timing and post-germination life history traits. We tested the hypotheses that germination season influences phenotypic expression of post-germination life history traits in the cold desert annual Isatis violascens and ...

journal_title：Scientific reports

authors： Lu JJ,Tan DY,Baskin CC,Baskin JM

更新日期：2016-04-27 00:00:00

abstract：:This manuscript presents a detailed characterization of active control of bow shock waves via leading edge injection, including subsonic coolant ejection and the appearance of Coanda effects. The flow phenomena occurring at steady and pulsating flow injection regimes were analyzed using steady and unsteady two-dimensi...

journal_title：Scientific reports

authors： Lozano F,Paniagua G

更新日期：2020-12-14 00:00:00

abstract：:Recently, CuZr-based bulk metallic glass (BMG) composites reinforced by the TRIP (transformation-induced plasticity) effect have been explored in attempt to accomplish an optimal of trade-off between strength and ductility. However, the design of such BMG composites with advanced mechanical properties still remains a ...

journal_title：Scientific reports

authors： Qin YS,Han XL,Song KK,Tian YH,Peng CX,Wang L,Sun BA,Wang G,Kaban I,Eckert J

更新日期：2017-02-13 00:00:00

abstract：:The exovesicles (EVs) are involved in pathologic host-parasite immune associations and have been recently used as biomarkers for diagnosis of infectious diseases. The release of EVs by Trypanosoma cruzi, the causative agent of Chagas disease, has recently been described, with different protein cargoes including the MA...

journal_title：Scientific reports

authors： Díaz Lozano IM,De Pablos LM,Longhi SA,Zago MP,Schijman AG,Osuna A

更新日期：2017-03-15 00:00:00

abstract：:When we feel sad or depressed, our face invariably "drops". Conversely, when we try to cheer someone up, we might tell them "keep your smile up", so presupposing that modifying the configuration of their facial muscles will enhance their mood. A crucial assumption that underpins this hypothesis is that mental states a...

journal_title：Scientific reports

authors： Bulnes LC,Mariën P,Vandekerckhove M,Cleeremans A

更新日期：2019-08-13 00:00:00

abstract：:Overproduction and purification of membrane proteins are generally challenging and time-consuming procedures due to low expression levels, misfolding, and low stability once extracted from the membrane. Reducing processing steps and shortening the timespan for purification represent attractive approaches to overcome s...

journal_title：Scientific reports

authors： Hering J,Missel JW,Zhang L,Gunnarsson A,Castaldo M,Pedersen PA,Ek M,Gourdon P,Snijder HJ

更新日期：2020-09-30 00:00:00

abstract：:Alterations in the gut microbiome have been reported in liver cirrhosis, and probiotic interventions are considered a potential treatment strategy. This study aimed to evaluate the effects and mechanisms of Lactobacillus salivarius LI01, Pediococcus pentosaceus LI05, Lactobacillus rhamnosus GG, Clostridium butyricum M...

journal_title：Scientific reports

authors： Shi D,Lv L,Fang D,Wu W,Hu C,Xu L,Chen Y,Guo J,Hu X,Li A,Guo F,Ye J,Li Y,Andayani D,Li L

更新日期：2017-07-31 00:00:00

abstract：:MicroRNAs (miRNAs) have been reported to be involved in DNA damage response induced by ionizing radiation (IR). c-Myc is reduced when cells treated with IR or other DNA damaging agents. It is unknown whether miRNAs participate in c-Myc downregulation in response to IR. In the present study, we found that miR-449a enha...

journal_title：Scientific reports

authors： Mao A,Zhao Q,Zhou X,Sun C,Si J,Zhou R,Gan L,Zhang H

更新日期：2016-06-02 00:00:00

abstract：:Blowflies and houseflies are mechanical vectors inhabiting synanthropic environments around the world. They feed and breed in fecal and decaying organic matter, but the microbiome they harbour and transport is largely uncharacterized. We sampled 116 individual houseflies and blowflies from varying habitats on three co...

journal_title：Scientific reports

authors： Junqueira ACM,Ratan A,Acerbi E,Drautz-Moses DI,Premkrishnan BNV,Costea PI,Linz B,Purbojati RW,Paulo DF,Gaultier NE,Subramanian P,Hasan NA,Colwell RR,Bork P,Azeredo-Espin AML,Bryant DA,Schuster SC

更新日期：2017-11-24 00:00:00

abstract：:Genetic polymorphisms in drug metabolizing enzymes and drug transporters may affect irinotecan toxicity. Although genetic polymorphisms have been shown to influence the irinotecan toxicity, data are limited in Thai population. Thus, the aim of this study was to assess the allele and genotype frequencies and the relati...

journal_title：Scientific reports

authors： Atasilp C,Chansriwong P,Sirachainan E,Reungwetwattana T,Sirilerttrakul S,Chamnanphon M,Puangpetch A,Sukasem C

更新日期：2020-08-10 00:00:00

abstract：:Deubiquitinase MYSM1 has been shown to play a critical role in hematopoietic cell differentiation and hematopoietic stem cell (HSC) maintenance. Mesenchymal stem cells (MSCs) are multipotent stromal cells within the bone marrow. MSCs are progenitors to osteoblasts, chondrocytes, adipocytes, and myocytes. Although, MSC...

journal_title：Scientific reports

authors： Li P,Yang YM,Sanchez S,Cui DC,Dang RJ,Wang XY,Lin QX,Wang Y,Wang C,Chen DF,Chen SY,Jiang XX,Wen N

更新日期：2016-02-26 00:00:00

abstract：:LiYF4:Eu nanophosphors with a single tetragonal phase are synthesized, and various strategies to enhance the Eu(3+) emission from the nanophosphors are investigated. The optimized Eu(3+) concentration is 35 mol%, and the red emission peaks due to the (5)D0 →(7)FJ (J = 1 and 2) transitions of Eu(3+) ions are further en...

journal_title：Scientific reports

authors： Kim SY,Won YH,Jang HS

更新日期：2015-01-19 00:00:00

abstract：:Combining chemotherapy and targeted therapies has resulted in an enhanced survival in metastatic colorectal cancer (mCRC) patients. However, the result of this palliative treatment in patients with metachronous peritoneal carcinomatosis (PC) remains unknown. The current population-based study aims to investigate the u...

journal_title：Scientific reports

authors： van Oudheusden TR,Razenberg LG,van Gestel YR,Creemers GJ,Lemmens VE,de Hingh IH

更新日期：2015-12-21 00:00:00

abstract：:Glucokinase (GK), the hexokinase involved in glucosensing in pancreatic β-cells, is also expressed in arcuate nucleus (AN) neurons and hypothalamic tanycytes, the cells that surround the basal third ventricle (3V). Several lines of evidence suggest that tanycytes may be involved in the regulation of energy homeostasis...

journal_title：Scientific reports

authors： Uranga RM,Millán C,Barahona MJ,Recabal A,Salgado M,Martinez F,Ordenes P,Elizondo-Vega R,Sepúlveda F,Uribe E,García-Robles MLÁ

更新日期：2017-06-16 00:00:00

abstract：:Gliomas are highly invasive brain tumours characterised by poor prognosis and limited response to therapy. There is an ongoing debate on the therapeutic potential of vaso-modulatory interventions against glioma invasion. Prominent vasculature-targeting therapies involve tumour blood vessel deterioration and normalisat...

journal_title：Scientific reports

authors： Alfonso JC,Köhn-Luque A,Stylianopoulos T,Feuerhake F,Deutsch A,Hatzikirou H

更新日期：2016-11-23 00:00:00

abstract：:Endonuclease V (EndoV) is a ubiquitous protein present in all three kingdoms of life, responsible for the specific cleavages at the second phosphodiester bond 3' to inosine. E. coli EndoV (EcEndoV) is the first member discovered in the EndoV family. It is a small protein with a compact gene organization, yet with a wi...

journal_title：Scientific reports

authors： Zhang Z,Jia Q,Zhou C,Xie W

更新日期：2015-08-05 00:00:00

abstract：:Changes in climate extremes pose far-reaching consequences to ecological processes and hydrologic cycles in alpine ecosystems of the arid mountain regions. Therefore, regional assessments in various climates and mountain regions are needed for understanding the uncertainties of the change trends for extreme climate ev...

journal_title：Scientific reports

authors： Lin P,He Z,Du J,Chen L,Zhu X,Li J

更新日期：2017-05-22 00:00:00

abstract：:With the continuous urbanization and industrialization in the world, energy saving and greenhouse gas (GHG) emission reduction have been serious issues to be addressed, for which heat recovery from traditional energy-intensive industries makes up a significant strategy. Here we report a novel approach to extract the w...

journal_title：Scientific reports

authors： Sun Y,Sridhar S,Liu L,Wang X,Zhang Z

更新日期：2015-11-12 00:00:00

abstract：:Developing an alternative method for fabricating microscale graphene patterns that overcomes the obstacles of organic contamination, linewidth resolution, and substrate damaging is paramount for applications in optoelectronics. Here we propose to pattern chemical vapor deposition grown graphene film through a stencil ...

journal_title：Scientific reports

authors： Wu Y,Tao H,Su S,Yue H,Li H,Zhang Z,Ni Z,Chen X

更新日期：2017-04-19 00:00:00