Abstract:
PURPOSE:Within five years after presentation 50-60% of patients with chronic limb-threatening ischemia (CLI) have died or had an amputation. We assessed the predictive value of lower extremity arterial calcification on computed tomography (CT) characteristics on both 7-years amputation-free survival and 10-years all-cause mortality in patients with CLI. METHOD:Included were 89 CLI patients (mean age 73.1 ± 11.6 years) who underwent a CT angiography of the lower extremities. In the femoropopliteal and crural arteries based on a CT score the following calcification characteristics were assessed: severity, annularity, thickness and continuity. The predictive value of different arterial calcification characteristics was analysed by age- and sex-adjusted multivariate Cox regression analysis. RESULTS:Complete annular calcifications were common (femoropopliteal 43.7%, n = 38; crural, 63.2%, n = 55). Mean survival was 278.4 weeks (95% CI 238.77-318.0 weeks). Patients with complete annular calcifications had a higher all-cause 10-year mortality (femoropopliteal unadjusted HR 1.64, p = 0.04 and adjusted for age and sex HR 1.68, p = 0.04; crural unadjusted HR 1.92, p = 0.02, adjusted for age and sex HR 2.29, p = 0.006) than patients with other calcification characteristics. CONCLUSIONS:Annularity of calcification of both femoropopliteal and crural arteries is a predictor for 10-year all-cause survival, its hazard being even higher than the traditional prognostic risk factors for CLI and therefore could be involved in the poor survival of these patients.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Konijn LCD,Takx RAP,de Jong PA,Spreen MI,Veger HTC,Mali WPTM,van Overhagen Hdoi
10.1016/j.ejrad.2020.109305subject
Has Abstractpub_date
2020-11-01 00:00:00pages
109305eissn
0720-048Xissn
1872-7727pii
S0720-048X(20)30494-0journal_volume
132pub_type
杂志文章abstract::There are many potential challenges to developing a high quality, efficient CT colonography service. Some are clear and predictable, for example creating CT capacity and securing financial resources, but some are less obvious, such as harnessing local support or changing referral practice amongst clinical colleagues. ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2012.03.018
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journal_title:European journal of radiology
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abstract:PURPOSE:To evaluate the awareness of radiation protection issues and the knowledge of dose levels of imaging procedures among medical students, radiology residents, and radiography students at an academic hospital. MATERIAL AND METHODS:A total of 159 young doctors and students (including 60 radiology residents, 56 med...
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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journal_title:European journal of radiology
pub_type: 杂志文章
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journal_title:European journal of radiology
pub_type: 杂志文章
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journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(99)00100-x
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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更新日期:1984-08-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.04.008
更新日期:2009-07-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2016.02.018
更新日期:2016-05-01 00:00:00
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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更新日期:2017-10-01 00:00:00
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更新日期:2018-09-01 00:00:00
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更新日期:2015-12-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2013-01-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:2013-09-01 00:00:00